scholarly journals Nutraceutical Properties of Legume Seeds: Phytochemical Compounds

2021 ◽  
Author(s):  
Hai Ha Pham Thi ◽  
Thanh Luan Nguyen
Keyword(s):  
Bioactive Compounds ◽  
Defense Mechanisms ◽  
Biological Activities ◽  
Antioxidant Properties ◽  
Antinutritional Factors ◽  
Negative Effects ◽  
Livestock Farming ◽  
Sustainable Food ◽  
Legume Seeds ◽  
Phytochemical Compounds

Legume seeds have an important role as nutraceuticals in human health (providing protein, carbohydrates, fiber, amino acids, and micronutrients) and act as sustainable food sources in livestock farming and aquaculture. Legume seeds contain a wide range of bioactive compounds that have significant health benefits, mainly classified under phenolic compounds, phytosterols, oligosaccharides, carbohydrates, and saponins. Some of these compounds play an important role in plant defense mechanisms against predators and environmental conditions. Heat-labile antinutritional factors (protease inhibitors and lectins) and heat-stable antinutritional factors (tannins and phytic acid) can be reduced by thermal treatment or postharvest to eliminate any potential negative effects from consumption. Substantial studies have demonstrated that these bioactive compounds possess multiple biological activities, including antioxidant properties, antibacterial, anticancer, anti-inflammatory, antidiabetic, cardiovascular protective. They also have various values for aquaculture, such as fishmeal alternative. In this review, the main bioactive compounds and important biological functions of legume seeds are summarized, and the mechanism of action is discussed.

scholarly journals Phytochemicals: Extraction and Preliminary Investigation of Bioactive Compounds from Rumex Vesicarius and Terminalia Catappa Plant

2019 ◽  
Vol 8 (3) ◽  
pp. 21-24
Author(s):  
Anandika Suryavanshi ◽  
Anand Murari Saxena
Keyword(s):  
Medicinal Plants ◽  
Bioactive Compounds ◽  
Metabolic Pathways ◽  
Biological Activities ◽  
Preliminary Investigation ◽  
Terminalia Catappa ◽  
Long Time ◽  
Soxhlet Method ◽  
Phytochemical Compounds

The present study was carried out for the determination of bioactive compounds from different extracts of Terminalia catappa and Rumex vesicarius. The plants are mines of several bioactive compounds also called as phytochemical compounds. These bioactive compounds are responsible for imparting such a potential medicinal property in the plants. The medicinal plant contains various types of bioactive compounds including phenols, alkaloids, terpenoids, tannins, glycosides, flavonoids etc. These bioactive compounds take part in various metabolic pathways and impart their effect. Terminalia catappa and Rumex vesicarius are such medicinal plants which are being used for medicinal purposes for long time. Both of them are rich source of potential bioactive compounds and hence carry out several biological activities effective for the treatment of various diseases. Hence the study focuses on determining the types of bioactive compounds they acquire. For this the leaves of T. catappa and dry stems of R. vesicarius were used for the extraction using different solvents with soxhlet method. The extract of different solvents was analyzed for the phytochemical test. The results obtained revealed that the type of solvents is crucial in determining the type of bioactive compounds to be present in extract. The results showed that ethanol and methanol are good solvent choice for extraction for these two plants. The results concludes that the presence of such potential and effective bioactive compounds in their extract makes them important medicinal plants and are hence employed for several researches and also used for treatment of various kinds of diseases.

scholarly journals Ethnomedicinal Use, Phytochemistry, Pharmacology, and Toxicology of Salvia verbenaca L. : A Review

2021 ◽  
Vol 12 (2) ◽  
pp. 1437-1469
Keyword(s):  
Essential Oils ◽  
Bioactive Compounds ◽  
Biological Activities ◽  
Traditional Use ◽  
Toxicological Effects ◽  
Stomach Pain ◽  
Toxicological Investigation ◽  
Phytochemical Compounds

Salvia verbenaca L. is a Mediterranean medicinal plant used traditionally to treat several diseases such as burns, ocular wounds, contusion, stomach pain, eye diseases, dermal inflammation. This review highlighted previous reports, including the botanical, taxonomical, geographical distribution, traditional use, phytochemical, biological, and toxicological effects of S. verbenaca. The data were gathered from scientific databases PubMed, Scopus, Web of Science, Google Scholar, ScienceDirect, SpringerLink. The presented data on S. verbenaca were organized according to ethnomedicinal use, bioactive compounds, pharmacology, and toxicological investigation. Ethnobotanical studies reported that many folk medicines use S. verbenaca, especially against wounds, burns, and cicatrization. The phytochemical compounds in different parts of S. verbenaca belonged to different classes of chemical compounds, including terpenoids, flavonoids, phenolic acids, phenolic diterpenoids, and fatty acids. The extracts and essential oils from S. verbenaca have a wide variety of in vitro and in vivo pharmacological activities, i.e., antioxidant, antifungal, antidiabetic, anti-inflammatory, antitumor, antihemolytic, antihypertensive, antileishmanial, and immunomodulatory activities. This research suggests that the biological activities of S. verbenaca prove its traditional uses. However, in-depth investigations are required, such as pharmacokinetic, pharmacodynamic, and toxicological experiments, to prove the efficacy and safety of S. verbenaca extracts and essential oils and their bioactive compounds.

scholarly journals Bioactive Compounds and Antioxidant Properties of Some Wild Plants with Potential Culinary Uses

2020 ◽  
Vol 71 (2) ◽  
pp. 179-184
Author(s):  
Gabriela Luta ◽  
Evelina Gherghina ◽  
Daniela Balan ◽  
Florentina Israel-Roming
Keyword(s):  
Bioactive Compounds ◽  
Neurological Diseases ◽  
Antioxidant Properties ◽  
Wild Plants ◽  
Potential Health ◽  
Diet Diversity ◽  
Edible Species ◽  
Phytochemical Compounds ◽  
Ancient Times ◽  
Culinary Uses

Since ancient times, wild plants have widely been traditionally consumed by different communities but today are gaining relevance due to their healthy properties. Vegetables, including wild edible species, constitute an important source of active natural products: micronutrients, especially vitamins and minerals and phytochemical compounds with antioxidant properties important in the prevention of various pathologies including degenerative, cardiovascular and neurological diseases. Some species of wild and cultivated edible plants were comparatively evaluated considering the content in bioactive compounds and the antioxidant capacity. Biochemical analysis of the fresh leaves indicated similar or even higher values of nutritive compounds (sugars, protids) and antioxidants (polyphenols, carotenoids, flavones, chlorophylls, ascorbic acid) in the species from spontaneous flora as dandelion (Taraxacum officinale), lesser celandine (Ficaria verna), wild garlic (Allium ursinum) than in the green lettuce and garden rocket commonly consumed around the world. Therefore, these wild plants could be recommended for consumers not only as new ingredients to improve their diet diversity but also for providing potential health benefits.

scholarly journals Amino acids, bioactive compounds and biological activities of ten species from family Commelinaceae in Thailand

2021 ◽  
Vol 49 (3) ◽  
pp. 12391
Author(s):  
Theeraphan CHUMROENPHAT ◽  
Surapon SAENSOUK
Keyword(s):  
Amino Acids ◽  
Vitamin C ◽  
Bioactive Compounds ◽  
Antioxidant Activities ◽  
Biological Activities ◽  
Antioxidant Properties ◽  
Total Flavonoid ◽  
Total Phenolic ◽  
Frap Assay ◽  
Few Data

Commelinaceae is used for ethnobotany. However, bioactive compounds information of this family is few data. The aim here was to determine the bioactive compounds and quantify the antioxidant activity from leaves 10 species.  Twenty amino acids were identified using LC/MS/MS. The antioxidant contents were evaluated by the total phenolic and total flavonoid content assays. The individual phenolic acids, flavonoids and vitamin c were identified by HPLC. The antioxidant activities detected were DPPH scavenging and FRAP assay. The total amino acids found in most samples studied ranging from 239 to 1012 µg/g DW. Vitamin C contents were in the range of 23 to 195 mg/100 g DW. Total phenolic and total flavonoid contents ranged from 11.3 to 35.7 mg GAE/g DW and 56.7 to 368.7 mg RE/100 g DW, respectively. All the species studied possessed strong antioxidant properties (DPPH and FRAP). This result can be applied for further development of functional foods or cosmetics.

scholarly journals GC-MS Analysis of Bioactive Compounds on Ethanolic Leaf Extract of Phyllodium pulchellum L. Desv.

2017 ◽  
Vol 9 (1) ◽  
Author(s):  
Velmurugan G. ◽  
Anand S. P.
Keyword(s):  
Gas Chromatography ◽  
Mass Spectrum ◽  
Bioactive Compounds ◽  
Leaf Extract ◽  
Biological Activities ◽  
Ms Analysis ◽  
Phytochemical Compounds ◽  
Minor Compounds ◽  
Therapeutic Activities ◽  
Ethanolic Leaf Extract

The present investigation was carried out to characterize the bioactive compounds present in leaf extract of Phyllodium pulchellum using Gas Chromatography-Mass Spectrum (GC-MS). The results of the GC-MS analysis provide different peaks determining the presence of 10 phytochemical compounds with different therapeutic activities. The major phytocompounds 9-Octadecenamide, (Z) (18.89), 9-Cyclohexylnonadecane (15.93), 2,2,2-trifluoroethyl 2- methyltetrahydro-5-oxo-3-furancarboxylate (10.47) and minor compounds were also present. From the results, it could be concluded that P.pulchellum contains various bioactive compounds have various biological activities. Therefore, it is recommended as a plant of phytopharmaceutical importance.

DYNAMICS OF BARLEY FLAVONOID AND PRODUCTIVITY UNDER UF-A RADIATION

1970 ◽  
pp. 14-18
Author(s):  
L. I. Goncharova ◽  
P. N. Tsygvintsev ◽  
О. А. Guseva
Keyword(s):  
Grain Yield ◽  
Defense Mechanisms ◽  
Antioxidant Defense ◽  
Malonic Dialdehyde ◽  
Growth Period ◽  
Negative Effects ◽  
Uv Spectrum ◽  
Quantum Energy ◽  
Dry Soil ◽  
Universal Mechanism

The effect of increased UV-A radiation during the ontogeny of barley plants of the Vladimir variety in the vegetation experiment was studied. Changes in the content of malonic dialdehyde, flavonoids and grain yield were revealed. UV-A radiation as compared to UV-B radiation, has lower quantum energy and can have both positive and negative effects on plant regulatory and photosynthetic processes. One of the most damaging effects of increased levels of UV-A radiation is oxidative stress, which causes lipid peroxidation of biological membranes. The existence of a plant cell in such conditions is possible only thanks to a system of antioxidant defense mechanisms. The accumulation of phenolic compounds under the action of UV radiation is a universal mechanism of protection against photodamage, which was formed in the early stages of the evolution of photoautotrophic organisms. Flavonoids are localized in the epidermis of plant tissues and act as an internal filter. The content of flavonoids is determined by the genotype and due to ontogenetic patterns. Plants were grown in a greenhouse, in vessels containing 4.5 kg of air-dry soil. The repetition is threefold (3 vessels in each variant). Sowing density - 13 plants in each vessel. As a source of UV-A radiation used lamps Black Light BLUE company Philips. Plants were irradiated for 5 hours a day from 10 to 15 hours at 13, 25, 34, 43 and 52 stages of organogenesis. The magnitude of the daily biologically effective dose of UV-A radiation was 60.7 kJ / m2. The solar part of the UV spectrum in the vegetation experiment was absent in the greenhouse. The nature of changes in the content of flavonoids under the action of UV-A irradiation during the growing season of plants with the dynamics of the oxidative process has been established. The first maximum was observed during the vegetative growth period, the second - at the earing stage. The data obtained indicate that flavonoids have ontogenetic conditionality and perform photoprotective functions. The increase in their content under the action of UV-A radiation is accompanied by an increase in resistance to photodamage, which is confirmed by the formation of grain yield.

Pharmacologically potentials of different substituted coumarin derivatives

2019 ◽  
Author(s):  
Chem Int
Keyword(s):  
Benzene Ring ◽  
Bioactive Compounds ◽  
Biological Activities ◽  
Pharmacological Properties ◽  
Coumarin Derivatives ◽  
Wide Range ◽  
Anti Oxidant ◽  
Anti Inflammatory ◽  
Coumarin Compounds

Coumarin and its derivatives are widely spread in nature. Coumarin goes to agroup as benzopyrones, which consists of a benzene ring connected to a pyronemoiety. Coumarins displayed a broad range of pharmacologically useful profile.Coumarins are considered as a promising group of bioactive compounds thatexhibited a wide range of biological activities like anti-microbial, anti-viral,antiparasitic, anti-helmintic, analgesic, anti-inflammatory, anti-diabetic, anticancer,anti-oxidant, anti-proliferative, anti-convulsant, and antihypertensiveactivities etc. The coumarin compounds have immense interest due to theirdiverse pharmacological properties. In particular, these biological activities makecoumarin compounds more attractive and testing as novel therapeuticcompounds.

The Impact of Plant Bioactive Compounds on Aging and Fertility of Diverse Organisms: A Review

2020 ◽  
Vol 20 (13) ◽  
pp. 1287-1299
Author(s):  
Muhammad Akram Mohd Noordin ◽  
Mahanem Mat Noor ◽  
Wan Mohd Aizat
Keyword(s):  
Clinical Trial ◽  
Bioactive Compounds ◽  
Defense Mechanisms ◽  
Healthy Aging ◽  
Antioxidant Defense ◽  
Senior Citizens ◽  
Aging Population ◽  
Human Clinical Trial ◽  
Fertility Reduction ◽  
The Impact

It is expected that in 2050, there will be more than 20% of senior citizens aged over 60 years worldwide. Such alarming statistics require immediate attention to improve the health of the aging population. Since aging is closely related to the loss of antioxidant defense mechanisms, this situation eventually leads to numerous health problems, including fertility reduction. Furthermore, plant extracts have been used in traditional medicine as potent antioxidant sources. Although many experiments had reported the impact of various bioactive compounds on aging or fertility, there is a lack of review papers that combine both subjects. In this review, we have collected and discussed various bioactive compounds from 26 different plant species known to affect both longevity and fertility. These compounds, including phenolics and terpenes, are mostly involved in the antioxidant defense mechanisms of diverse organisms such as rats, mites, fruit flies, roundworms, and even roosters. A human clinical trial should be considered in the future to measure the effects of these bioactive compounds on human health and longevity. Ultimately, these plant-derived compounds could be developed into health supplements or potential medical drugs to ensure a healthy aging population.

Flavones and Their Analogues as Bioactive Compounds – An Overview

2019 ◽  
Vol 16 (4) ◽  
pp. 377-391 ◽  
Author(s):  
B.S. Jayashree ◽  
H. Venkatachalam ◽  
Sanchari Basu Mallik
Keyword(s):  
Biological Activity ◽  
Free Radical ◽  
Bioactive Compounds ◽  
Antioxidant Properties ◽  
Radical Scavenging ◽  
Cost Effective ◽  
Free Radical Scavenging ◽  
Polyphenolic Compounds ◽  
Pharmacological Activities ◽  
Poor Solubility

Flavonoids constitute a large group of polyphenolic compounds that are known to have antioxidant properties, through their free radical scavenging abilities. They possess a chromone (γ- benzopyrone) moiety, responsible for eliciting many pharmacological activities. Even though, natural flavonoids are highly potent, owing to their poor solubility, they are less used. Therefore, attempts have been made to improve their stability, solubility, efficacy and kinetics by introducing various substituents on the flavone ring. For nearly the last two decades, flavones were synthesized in our laboratory by simple, convenient and cost-effective methods, with the knowledge of both synthetic and semi-synthetic chemistry. In this direction, it was considered worthwhile to present an overview on the synthesized flavonoids. This review creates a platform for highlighting various modifications done on the flavone system along with their biological activity.

scholarly journals Cyanobacteria—From the Oceans to the Potential Biotechnological and Biomedical Applications

Marine Drugs ◽  
2021 ◽  
Vol 19 (5) ◽  
pp. 241
Author(s):  
Shaden A. M. Khalifa ◽  
Eslam S. Shedid ◽  
Essa M. Saied ◽  
Amir Reza Jassbi ◽  
Fatemeh H. Jamebozorgi ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Biomedical Applications ◽  
Large Scale ◽  
Biological Activities ◽  
Scale Production ◽  
Pharmacological Activities ◽  
Large Scale Production ◽  
Marine Products ◽  
Hiv 1 ◽  
Successful Phase

Cyanobacteria are photosynthetic prokaryotic organisms which represent a significant source of novel, bioactive, secondary metabolites, and they are also considered an abundant source of bioactive compounds/drugs, such as dolastatin, cryptophycin 1, curacin toyocamycin, phytoalexin, cyanovirin-N and phycocyanin. Some of these compounds have displayed promising results in successful Phase I, II, III and IV clinical trials. Additionally, the cyanobacterial compounds applied to medical research have demonstrated an exciting future with great potential to be developed into new medicines. Most of these compounds have exhibited strong pharmacological activities, including neurotoxicity, cytotoxicity and antiviral activity against HCMV, HSV-1, HHV-6 and HIV-1, so these metabolites could be promising candidates for COVID-19 treatment. Therefore, the effective large-scale production of natural marine products through synthesis is important for resolving the existing issues associated with chemical isolation, including small yields, and may be necessary to better investigate their biological activities. Herein, we highlight the total synthesized and stereochemical determinations of the cyanobacterial bioactive compounds. Furthermore, this review primarily focuses on the biotechnological applications of cyanobacteria, including applications as cosmetics, food supplements, and the nanobiotechnological applications of cyanobacterial bioactive compounds in potential medicinal applications for various human diseases are discussed.

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