scholarly journals Sesquiterpene from Myanmar Medicinal Plant (Curcuma comosa)

2020 ◽  
Author(s):  
Khun Nay Win Tun ◽  
Nanik Siti Aminah ◽  
Alfinda Novi Kristanti ◽  
Hnin Thanda Aung ◽  
Yoshiaki Takaya

Curcuma comosa (Zingiberaceae) is widely grown in tropical and subtropical areas of Asia, like Thailand, Indonesia, Malaysia, and Myanmar. In Myanmar, the rhizome of Curcuma comosa is called Sa-nwin-ga, and local people had used it as a traditional medicine for stomach ache, diabetes mellitus, and hypertension. This species produces secondary metabolites of phenolic and nonphenolic groups. Phenolic groups like diarylheptanoids and flavonoids. While nonphenolics are terpenoids, especially sesqui- and monoterpenes. In this chapter, the group of sesquiterpene compounds from Curcuma comosa starts from the isolation technique, followed by the elucidation of the molecular structure, and their activity tests have been discussed.

2018 ◽  
Vol 10 (1) ◽  
pp. 53
Author(s):  
Arif Soeksmanto

Mahkota dewa (Phaleria macrocarpa [Scheff.] Boerl.) is an Indonesians traditional medicinal plant used to treat various diseases, such as diabetes mellitus, hemorrhoid, impotency and cancer. Almost all parts of the plants canbe used as traditional medicine, but if directly consumed, it can cause swollen, sprue, numb at tongue, fever, even unconsciousness. This research was carried out to find out recovery of liver tissue damage of mice administered intraperitoneally with subchronic dosage of butanol extract 170 mg/kg body weight. Observation on first week showed that there is light degeneration (vacuolization) which is getting better on second week and apparentlynormal on forth week.


Author(s):  
Arzumand Ara ◽  
Md. Moshfekus Saleh-E-In ◽  
Md. Abul Hashem ◽  
Mesbahuddin Ahmad ◽  
Choudhury Mahmood Hasan

Abstract Background Adenanthera pavonina L. is an important medicinal plant and its barks are used in traditional medicine for treating different diseases. Therefore, a phytochemical investigation was carried out to isolate and identify secondary metabolites from its barks. Results Seven compounds namely ethyl 3,3-dimethyl-13-hydroxytridecanoate (1), stigmasta-5,22-dien-3β-ol (2), tert.butyl tridecanoate (3), 6-α-hydroxy stigmast-20(21)-en-3-one (4) of dichloromethane extract and 18-(2′, 3′-dihydroxyphenyl)nonadec-17-en-2-ol (5), 1-(N-propyl amino)-2-henecosanone (6), and stigmast–5(6), 20(21)-diene-3-one (7) were isolated from the barks of Adenanthera pavonina Linn. Of these compounds, 1, 4, 5, 6, and 7 appear new. The structures of these compounds were elucidated by spectroscopic techniques, mainly by NMR. Conclusions Five new and two known compounds have been isolated and characterized from the bark of A. pavonina. The isolated compounds could be a potential template for the synthesis and development of new lead compounds with interesting pharmacological properties. Graphical abstract


2020 ◽  
Vol 8 (2) ◽  
pp. 153-163
Author(s):  
Meity Marviana Laut ◽  
Nemay Ndaong ◽  
Filphin Amalo ◽  
Larry Toha ◽  
Herlina Umbu Deta

Acalypha indica Linn is a tropical weed, grows annually in East Nusa Tenggara. The weed is member of Euphorbiaceae family, a largest plant family known as medicinal plant. The weed leaves were used by local people in NTT to treat wounds, diseases or myasis on their livestock. This study aim to investigate the secondary metabolites in A. indica L leaves as a scientific proven for its local use.  The extract preparation comprises of several steps, i.e collection of fresh leaves, dry and wet sortation. The clean leaves were air dried in a room temperature for about 2 weeks before grounded into powder and subjected to extraction. The extraction method was maceration with ethanol 96% as solvent. The dense extract was evaporated using rotary evaporator and subjected to phytochemical screening. The result shows that ethanol extract of A.indica leaves were tested positive for flavonoid and tannin. Alkaloid, saponins, triterpenes and steroid were tested negative on the extract.


2019 ◽  
Vol 3 (1) ◽  
pp. 26
Author(s):  
Marina Silalahi

<p><em>Orthosiphon stamineus</em> Benth., or <em>kumis kucing</em> is a the medicinal plants have been used as diuretic medicine. The utilization of medicinal plants associated to its secondary metabolite. This article aims to explain uses pf the <em>O. stamineus</em> and the its secondary metabolites. This article is based on literature offline and online media. Offline literature used the books, whereas online media used Web, Scopus, Pubmed, and scientific journals. <em>Orthosiphon stamineus</em> has two varieties called purple varieties (which have purple-colored flowers) and white varieties (which have white-colored flowers). Some of secondary metabolites in the <em>O. stamineus </em>are the terpenoids, phenols, isopimaran type ispenimoids, flavonoids, benzochromes, and organic acid derivatives. The traditional medicine of the <em>Orthosiphon stamineus</em> uses as the diuretic, hypertension, hepatitis, jaundice, and diabetes mellitus.</p><p> <em></em></p><p><strong>Keywords</strong>: <em>Orthosiphon stamineu</em><em>s</em><em>, diuretics, diterpenoids, hypertension</em></p><p> </p>


2021 ◽  
Author(s):  
Orou G. Gaoue ◽  
Kowiyou Yessoufou ◽  
Ledile Mankga ◽  
Fifanou Vodouhe

2011 ◽  
Vol 2011 ◽  
pp. 1-12 ◽  
Author(s):  
N. J. Yob ◽  
S. Mohd. Jofrry ◽  
M. M. R. Meor. Mohd. Affandi ◽  
L. K. Teh ◽  
M. Z. Salleh ◽  
...  

Zingiber zerumbetSm., locally known to the Malay as “Lempoyang,” is a perennial herb found in many tropical countries, including Malaysia. The rhizomes ofZ. zerumbet, particularly, have been regularly used as food flavouring and appetizer in various Malays' cuisines while the rhizomes extracts have been used in Malay traditional medicine to treat various types of ailments (e.g., inflammatory- and pain-mediated diseases, worm infestation and diarrhea). Research carried out using differentin vitroandin vivoassays of biological evaluation support most of these claims. The active pharmacological component ofZ. zerumbetrhizomes most widely studied is zerumbone. This paper presents the botany, traditional uses, chemistry, and pharmacology of this medicinal plant.


Author(s):  
Abdul Nasir ◽  
Atif Ali Khan Khalil ◽  
Muhammad Zeeshan Bhatti ◽  
Ashfaq Ur Rehman ◽  
Jiayi Li ◽  
...  

: Persicaria hydropiper (L.) Delarbre (family Polygonacea), commonly known as Polygonum hydropiper, is a popular medicinal plant used in traditional medicine. The plant is indigenous to the tropical northern hemisphere and temperate zone including China, Bangladesh, India, and Japan. The plant is used in folk medicine for numerous ailments such as hemorrhoids, antifertility, diarrhea, and dyspepsia. Its medicinal usage in Unani, Ayurveda, Siddha, and other traditional medicine is well-recognized. So far, a wide range of active phytochemicals of this plant has been identified, such as flavonoids, sulphated flavonoids, terpenoids, anthraquinones, steroids, coumarin, simple phenolics, and others. Pharmacological data reported in the literature suggest that various parts of P. hydropiper exhibit antimicrobial, antioxidant, hypoglycemic, antidepressant, cardioprotective, hepatoprotective, anticancer, and antifertility effects. The present review aim is to compile the coherently document research on the phytochemical, pharmacological, and biological activities of P. hydropiper from different parts of the globe.


2021 ◽  
pp. 50-59
Author(s):  
Karma Sherub ◽  
Bhagat Suberi ◽  
Purna Prasad Chapagai ◽  
. Penjor ◽  
Kelzang Jurmey ◽  
...  

Medicinal plants are one of the most affordable and accessible method available for the treatment of various ailments and diseases by the local people. In this regards, the study aimed to document the ethno-medicinal knowledge of plants used by the local people of Dagana district of Bhutan. Data were collected between June and November of 2020 using semi-structured interviews from the local people, following snowball sampling.  The study documented 74 medicinal plant species, used for treating 30 different body ailments and diseases. Maximum number of species (14) was used in treating cut/body wounds and commonly used plant parts was leaves (30 species). Current study area was found to be rich in ethno-medicinal knowledge, but equally threatened with declining practices and management of resources. Thus, appropriate conservation of resources and preservation of traditional knowledge is required.


Molecules ◽  
2021 ◽  
Vol 26 (20) ◽  
pp. 6311
Author(s):  
Paulina J. Cázares-Samaniego ◽  
Claudia G. Castillo ◽  
Miguel A. Ramos-López ◽  
Marco M. González-Chávez

Ulomoides dermestoides are used as a broad-spectrum medical insect in the alternative treatment of various diseases. Preliminary volatilome studies carried out to date have shown, as the main components, methyl-1,4-benzoquinone, ethyl-1,4-benzoquinone, 1-tridecene, 1-pentadecene, and limonene. This work focused on the production of metabolites and their metabolic variations in U. dermestoides under stress conditions to provide additional valuable information to help better understand the broad-spectrum medical uses. To this end, VOCs were characterized by HS-SPME with PEG and CAR/PDMS fibers, and the first reported insect essential oils were obtained. In HS-SMPE, we found 17 terpenes, six quinones, five alkenes, and four aromatic compounds; in the essential oils, 53 terpenes, 54 carboxylic acids and derivatives, three alkynes, 12 alkenes (1-Pentadecene, EOT1: 77.6% and EOT2: 57.9%), 28 alkanes, nine alkyl disulfides, three aromatic compounds, 19 alcohols, three quinones, and 12 aldehydes were identified. Between both study approaches, a total of 171 secondary metabolites were identified with no previous report for U. dermestoides. A considerable number of the identified metabolites showed previous studies of the activity of pharmacological interest. Therefore, considering the wide variety of activities reported for these metabolites, this work allows a broader vision of the therapeutic potential of U. dermestoides in traditional medicine.


2017 ◽  
Vol 1 (2) ◽  
pp. 85
Author(s):  
Muhammad Hamzah Solim ◽  
Y. S. Wulan Manuhara

Talinum paniculatum Gaertn. is one of traditional medicinal plant in Indonesia which has benefits such as for vitality and maintain blood circulation. The aim of this research is to obtain biomass production of root and shoot of T. paniculatum Gaertn. by liquid and solid MS medium with IBA. This research conducted to provide biomass as raw material for secondary metabolites test. Stems as explant were induced with four treatments (liquid MS, solid MS, liquid MS + 2 ppm IBA and solid MS + 2 ppm IBA) with five repetitions. Observation did for 28 days. The parameters are the percentage of explants which formed the root and shoot, morphology, fresh and dry biomass. Result shows that percentage of root and shoot have 100% in liquid and solid MS + 2 ppm IBA. Fresh and dry biomass of root and shoot in solid MS + 2 ppm IBA higher than the others. This research found callus in liquid and solid MS + 2 ppm IBA. Morphology of root in liquid MS has thin and friable, but thick in solid MS. Shoot in solid and liquid MS has thin, short and sturdy.


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