scholarly journals The Importance of Happy Hypoxemia in COVID-19

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Katayoun Haryalchi ◽  
Abtin Heidarzadeh ◽  
Mahmood Abedinzade ◽  
Sepehr Olangian Tehrani ◽  
Samaneh Ghazanfar Tehran

Background: Nowadays, the new coronavirus (SARS-CoV-2) and its complications are one of the main concerns of the world. One of the most severe complications of COVID-19 is hypoxemia. Objectives: This study aimed to assess the importance of happy hypoxemia in COVID-19. Methods: We systematically searched web of science, PubMed, and Google scholar databases to find articles related to COVID-19 and happy hypoxemia. Results: COVID-19 causes a type of hypoxemia named silent (happy) hypoxemia, which has an atypical clinical presentation. This type of hypoxemia has not been noted before in viral pneumonia, and there is no specific treatment for this serious complication. Patients with silent hypoxemia may develop severe hypoxemia without dyspnea and with near-normal lung compliance. These patients are awake, calm, and responsive. Although their lungs are not oxygenated efficiently, they are alert and cooperative. Their condition may be deteriorated rapidly without warning and causes death. Conclusions: According to the findings, paying attention to happy hypoxemia is important for improving the health status of COVID-19 patients.

2020 ◽  
Author(s):  
Jyotirmayee Turuk ◽  
Subrata Kumar Palo ◽  
Sonalika Rath ◽  
Jyotsnamayee Sabat ◽  
Subhra Subhadra ◽  
...  

Abstract Background: Dengue is a widespread disease affecting many countries and about two fifth of the world is at risk for this disease. In India, the dengue incidence has increased in recent past and emerged as an important health problem in many states including Odisha. Cases with dengue co-infection with other diseases usually have atypical clinical presentation.Methods: A facility based longitudinal study was carried out over a period of one year to determine the dengue co-infection and its outcome. The suspected cases were clinically assessed following a standard case report format and serological investigations including serotyping were carried out.Results: 33.6% samples were dengue positive of which 78.5% were positive for NS1 Ag, 26.6% positive for dengue IgM and 5.1% to both. Among the dengue positive cases, 60.9% were male and mean age was 31.52 (+/- 17.03) years. High occurrence of cases was during May to November with maximum in August. Among the 975 dengue positives, 57 (5.8%) were found to have co-infection. Chikungunya was the most common co-infection in 71.9%, followed by herpes simplex (HSV) (7%) and other diseases. Fever was the most common presenting symptom (98.2%), followed by myalgia (91.2%), pain abdomen (12.3%), Rash/lesion (8.8%), burning micturition (5.3%), Petechiae (1.7%) and Pruritus (1.7%) among the co-infected cases.While DEN-2 serotype was observed in majority (74.1%) more than two serotypes was found in 5.85% of dengue positives .Conclusions: All the four dengue serotypes were found to be circulating with DEN-2 as the most predominant one. About 5.8% of dengue cases have co-infection (mainly with chikungunya) and clinically present with atypical signs and symptoms.


2014 ◽  
Vol 50 (2) ◽  
pp. 130-135 ◽  
Author(s):  
Anya N. Gambino ◽  
Pamela J. Mouser ◽  
G. Diane Shelton ◽  
Nena J. Winand

This report describes a case of feline dystrophin-deficient muscular dystrophy (DDMD) with an atypical clinical presentation. A novel gene mutation is reported to be responsible for dystrophin-deficient hypertrophic muscular dystrophy. In an emergency setting, clinicians should be aware of muscular dystrophy in young cats and the importance of elevated creatine kinase (CK) activity. Muscular dystrophy is rare but can present both a diagnostic and therapeutic challenge in an emergency setting. Patients with muscular dystrophy have a progressive disease with no specific treatment and have an increased risk for death during their hospital stay.


Author(s):  
Lucía García-García ◽  
Guzmán Antonio Muñoz-Fernández ◽  
José Miguel Valverde-Roda ◽  
Antonio Menor-Campos

Flamenco is a living art that excites and awakens the senses of those who witness such a dance, singing and guitar show. It is a way of expressing feelings. Flamenco was considered a world intangible heritage of humanity by UNESCO and is a part of the identity and culture of Andalucía, place where it originated. Flamenco is a symbol of Spanish culture around the world. In addition, it has been discovered that there is a typology of flamenco tourists whose motivation is related to the search of experience and authenticity in the tourist destination. A search of published scientific articles on emotional tourism, motivation and flamenco has been conducted using three databases: Web of Science, Scopus and Google Scholar. Flamenco is an art that transmits passion in each of its three components: song, dance and music. Therefore, tourism management of the sites where flamenco is part of its identity must bet on its development and potential as a motivating factor to travel, bringing the emotion to the tourist, which consists not only in perceiving it, but also in experiencing it, living it. We conclude that Flamenco as a living art forms an essential part of Spain’s cultural heritage and becomes an important tourist factor to cover the experiential needs of tourists.


Author(s):  
Lucía García-García ◽  
Guzmán Antonio Muñoz-Fernández ◽  
José Miguel Valverde-Roda ◽  
Antonio Menor-Campos

Flamenco is a living art that excites and awakens the senses of those who witness such a dance, singing and guitar show. It is a way of expressing feelings. Flamenco was considered a world intangible heritage of humanity by UNESCO and is a part of the identity and culture of Andalucía, place where it originated. Flamenco is a symbol of Spanish culture around the world. In addition, it has been discovered that there is a typology of flamenco tourists whose motivation is related to the search of experience and authenticity in the tourist destination. A search of published scientific articles on emotional tourism, motivation and flamenco has been conducted using three databases: Web of Science, Scopus and Google Scholar. Flamenco is an art that transmits passion in each of its three components: song, dance and music. Therefore, tourism management of the sites where flamenco is part of its identity must bet on its development and potential as a motivating factor to travel, bringing the emotion to the tourist, which consists not only in perceiving it, but also in experiencing it, living it. We conclude that Flamenco as a living art forms an essential part of Spain’s cultural heritage and becomes an important tourist factor to cover the experiential needs of tourists.


2021 ◽  
pp. 3-8
Author(s):  
Б.В. Анисимов

Рассмотрены современные тенденции мирового рынка картофеля в связи с меняющейся ситуацией за последние десятилетия в сфере производства, структуры целевого использования и потребления картофеля и его роли в современных агропродовольственных системах разных стран и регионов мира. Анализ проведен на основе данных мировой статистики, материалов из различных баз данных и интернет-источников (Web of Science, Scopus, Google Scholar, РИНЦ и др.), а также авторских работ, опубликованных за последние годы в широко известных международных изданиях (Springer, Wageningen Academic Publishers и др.). По оценкам FAO, площадь возделывания картофеля в странах мира составляет 19 млн га, а общий объем мирового производства картофеля оценивается на уровне 378 млн т. На продовольственное потребление приходится примерно две трети урожая картофеля (64%), на корм для животных – 12%, на семенные и другие цели –21%. Начиная с 2005 года, общий объем производства картофеля в развивающихся странах впервые превысил сложившиеся показатели производства картофеля в странах развитых экономик. В Латинской Америке наиболее крупные производители картофеля – Перу (4,7 млн т) и Колумбия (2,8 млн т). В Северной Америке (США, Канада) общий объем производства картофеля составляет 24,4 млн т. США традиционно находятся в пятерке мировых лидеров по объему производства картофеля (20 млн т). В странах ЕС крупнейшими производителями картофеля традиционно остаются Германия, Франция, Нидерланды, Великобритания и Бельгия. Динамичное развитие европейской индустрии переработки картофеля во многом способствовало поддержанию высокого уровня производства картофеля в этом регионе. Среди стран Восточной Европы лидирующие позиции по объемам производства картофеля занимают Россия, Украина, Беларусь и Польша, где потребление на душу населения традиционно превышает 90-100 кг в год, в то время как в среднем по всему европейскому региону этот показатель составляет 83,4 кг в расчете на одного жителя. Ключевые слова: картофель, рынок, производство, потребление, целевое использование. The article considers the current trends of the world potato market in connection with the changing situation over the past decades in the field of production, the structure of the intended use and consumption of potatoes and its role in modern agro-food systems of different countries and regions of the world. The analysis was carried out on the basis of world statistics data, materials from various databases and Internet sources (Web of Science, Scopus, Google Scholar, RSCI, etc.), as well as author's works published in recent years in well-known international publications (Springer, Wageningen Academic Publishers, etc.) According to FAO estimates, the area of potato cultivation in the world is 19 million hectares, and the total world potato production is estimated at 378 million tons. Food consumption accounts for about two-thirds of the potato crop (64%), 12% for animal feed, 21% for seed and other purposes. Since 2005, the total volume of potato production in developing countries for the first time exceeded the established indicators of potato production in developed economies. In Latin America, the largest potato producers are Peru (4.7 million tons) and Colombia (2.8 million tons). In North America (USA, Canada), the total potato production is 24.4 million tons. The United States is traditionally among the top five world leaders in terms of potato production (20 million tons). In the EU countries, the largest potato producers are traditionally Germany, France, the Netherlands, the United Kingdom and Belgium. The dynamic development of the European potato processing industry has largely contributed to maintaining a high level of potato production in this region. Among the countries of Eastern Europe, the leading positions in terms of potato production are occupied by Russia, Ukraine, Belarus and Poland, where per capita consumption traditionally exceeds 90-100 kg per year, while the average for the entire European region is 83.4 kg per inhabitant.


Author(s):  
Tatiani De Azevedo Lobo ◽  
Marli M. Moraes Da Costa

Resumo: O presente ensaio busca apresentar e fomentar algumas questões pertinentes ao debate contemporâneo sobre a pobreza, demonstrando a importância do tema no cenário mundial. Para tanto, inicialmente discorre-se sobre a construção histórico-social da pobreza e suas características contemporâneas. Com efeito, aponta-se a limitação dos fatores tradicionalmente apresentados como causadores da pobreza, como cultura, genética, geografia etc. Além disso, apresentam-se as formas atuais de monitorar o fenômeno, como o coeficiente de Gini e o IDH. Posteriormente, aborda-se a distribuição mundial da pobreza. Nesse ponto, colaciona-se que a pobreza é um problema mundial. No entanto, é perceptível que o Sul ainda concentra maior número de indivíduos pobres do que o Norte. Na esteira dos últimos dados da pesquisa realizada pelas Nações Unidas, houve uma nítida ascensão do Sul, especialmente nos indicadores sociais ligados à educação. A seguir, trata-se do capital social e da Teoria das Capacidades, apresentando-se novas abordagens da pobreza. Assim, o capital social trata de uma ideia utilizada para verificar a rede de relacionamento dos indivíduos. Já a Teoria das Capacidades está ligada com a ideia de oportunidade da liberdade. Por fim, estuda-se as políticas públicas, bem como seu aspecto fragmentário. Conclui-se, assim, sobre a necessidade de implementação de políticas públicas elaboradas sob a égide de novos paradigmas, a fim de possibilitar o tratamento específico do fenômeno da pobreza, conforme as peculiaridades de cada local. Para tanto foi utilizado neste trabalho o método de abordagem hipotético-dedutivo, o método de procedimento monográfico e a técnica de pesquisa, operacionalizados por meio do emprego de vasta pesquisa bibliográfica. Abstract: This essay seeks to provide and foster some relevant to the contemporary debate on poverty issues, demonstrating the importance of the issue on the world stage. For this purpose, initially spoke about the historical and social construction of poverty and its contemporary features. Indeed, he pointed out the limitation of the factors traditionally presented as the cause of poverty, as a culture, genetics, geography, etc. Furthermore, we presented the current ways of monitoring the phenomenon, such as the Gini coefficient and the HDI. Subsequently addressed the global distribution of poverty. At this point, if collated that poverty is a worldwide problem. However, it is apparent that the South still more concentrated than the poor North individuals. In the wake of recent data from research conducted by the United Nations, there was a sharp rise in the South, especially in social indicators related to education. Next, we treated the capital and the Theory of Capabilities, presenting new approaches to poverty. Thus, social capital is an idea used to verify the relationship network of individuals. Already Capabilities Theory is linked with the idea of freedom of opportunity. Finally, we studied public policy, as well as its fragmentary appearance. Thus, it is concluded on the need to implement public policies prepared under the aegis of new paradigms to enable specific treatment of the phenomenon of poverty, according to the peculiarities of each site. For that was used in this work the method of hypothetical-deductive approach, the method of procedure and the monographic research technique, operationalized through the use of extensive academic research.


2021 ◽  
Vol 22 (14) ◽  
pp. 7463
Author(s):  
Ismat Majeed ◽  
Komal Rizwan ◽  
Ambreen Ashar ◽  
Tahir Rasheed ◽  
Ryszard Amarowicz ◽  
...  

The Mimosa genus belongs to the Fabaceae family of legumes and consists of about 400 species distributed all over the world. The growth forms of plants belonging to the Mimosa genus range from herbs to trees. Several species of this genus play important roles in folk medicine. In this review, we aimed to present the current knowledge of the ethnogeographical distribution, ethnotraditional uses, nutritional values, pharmaceutical potential, and toxicity of the genus Mimosa to facilitate the exploitation of its therapeutic potential for the treatment of human ailments. The present paper consists of a systematic overview of the scientific literature relating to the genus Mimosa published between 1931 and 2020, which was achieved by consulting various databases (Science Direct, Francis and Taylor, Scopus, Google Scholar, PubMed, SciELO, Web of Science, SciFinder, Wiley, Springer, Google, The Plant Database). More than 160 research articles were included in this review regarding the Mimosa genus. Mimosa species are nutritionally very important and several species are used as feed for different varieties of chickens. Studies regarding their biological potential have shown that species of the Mimosa genus have promising pharmacological properties, including antimicrobial, antioxidant, anticancer, antidiabetic, wound-healing, hypolipidemic, anti-inflammatory, hepatoprotective, antinociceptive, antiepileptic, neuropharmacological, toxicological, antiallergic, antihyperurisemic, larvicidal, antiparasitic, molluscicidal, antimutagenic, genotoxic, teratogenic, antispasmolytic, antiviral, and antivenom activities. The findings regarding the genus Mimosa suggest that this genus could be the future of the medicinal industry for the treatment of various diseases, although in the future more research should be carried out to explore its ethnopharmacological, toxicological, and nutritional attributes.


2021 ◽  
Vol 10 (11) ◽  
pp. 2439
Author(s):  
Jerome R. Lechien ◽  
Stéphane Hans ◽  
Francois Bobin ◽  
Christian Calvo-Henriquez ◽  
Sven Saussez ◽  
...  

Background: Laryngopharyngeal reflux (LPR) is a common disease in otolaryngology characterized by an inflammatory reaction of the mucosa of the upper aerodigestive tract caused by digestive refluxate enzymes. LPR has been identified as the etiological or favoring factor of laryngeal, oral, sinonasal, or otological diseases. In this case series, we reported the atypical clinical presentation of LPR in patients presenting in our clinic with reflux. Methods: A retrospective medical chart review of 351 patients with LPR treated in the European Reflux Clinic in Brussels, Poitiers and Paris was performed. In order to be included, patients had to report an atypical clinical presentation of LPR, consisting of symptoms or findings that are not described in the reflux symptom score and reflux sign assessment. The LPR diagnosis was confirmed with a 24 h hypopharyngeal-esophageal impedance pH study, and patients were treated with a combination of diet, proton pump inhibitors, and alginates. The atypical symptoms or findings had to be resolved from pre- to posttreatment. Results: From 2017 to 2021, 21 patients with atypical LPR were treated in our center. The clinical presentation consisted of recurrent aphthosis or burning mouth (N = 9), recurrent burps and abdominal disorders (N = 2), posterior nasal obstruction (N = 2), recurrent acute suppurative otitis media (N = 2), severe vocal fold dysplasia (N = 2), and recurrent acute rhinopharyngitis (N = 1), tearing (N = 1), aspirations (N = 1), or tracheobronchitis (N = 1). Abnormal upper aerodigestive tract reflux events were identified in all of these patients. Atypical clinical findings resolved and did not recur after an adequate antireflux treatment. Conclusion: LPR may present with various clinical presentations, including mouth, eye, tracheobronchial, nasal, or laryngeal findings, which may all regress with adequate treatment. Future studies are needed to better specify the relationship between LPR and these atypical findings through analyses identifying gastroduodenal enzymes in the inflamed tissue.


2021 ◽  
Vol 14 (3) ◽  
pp. 217
Author(s):  
Jiri Patocka ◽  
Kamil Kuca ◽  
Patrik Oleksak ◽  
Eugenie Nepovimova ◽  
Martin Valis ◽  
...  

Since December 2019, SARS-CoV-2 (COVID-19) has been a worldwide pandemic with enormous consequences for human health and the world economy. Remdesivir is the only drug in the world that has been approved for the treating of COVID-19. This drug, as well as vaccination, still has uncertain effectiveness. Drug repurposing could be a promising strategy how to find an appropriate molecule: rapamycin could be one of them. The authors performed a systematic literature review of available studies on the research describing rapamycin in association with COVID-19 infection. Only peer-reviewed English-written articles from the world’s acknowledged databases Web of Science, PubMed, Springer and Scopus were involved. Five articles were eventually included in the final analysis. The findings indicate that rapamycin seems to be a suitable candidate for drug repurposing. In addition, it may represent a better candidate for COVID-19 therapy than commonly tested antivirals. It is also likely that its efficiency will not be reduced by the high rate of viral RNA mutation.


Author(s):  
Endurance Uzobo ◽  
Aboluwaji D Ayinmoro

Background As it is common with the most devastating events in the world, women always seem to be at the most disadvantage position. This situation manifested during the period of COVID-19 lockdown throughout the world and Africa in particular. The purpose of this study is to explore Domestic Violence (DV) cases in African during the COVID-19 lockdown. Methods Data for this study were gleaned from an electronic literature search using various databases PubMed and BioMed Central, Web of Science, etc. Key search words were gender DV during and after COVID-19. A total of 68 records were identified during the search. However, only 46 of these sources met the inclusion criteria. Results From the review done in selected African countries which include Egypt, South Africa, Kenya, Nigeria, Ghana and Zimbabwe; it was discovered that COVID-19 lockdown across these countries worsens the already existing cases of DV. The study also noted that generally, the response of the government has been very poor in terms of dealing with DV cases in the period of COVID-19 lockdown. Conclusion The study concluded that despite the failures of government in tackling the DV pandemics, NGOs have been very active in championing the cause of those violated while also trying to provide succour to victims. Thus, the study recommended that countries in Africa need to join international initiatives in prioritising DV cases while trying to deal with the virus itself. Thus, one disease should not be traded for another.


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