scholarly journals Parallel and Concurrent Infection of Dengue Virus and Plasmodium falciparum among Patients with Febrile Illnesses Attending Bingham University Health Centre, Karu, Nigeria

Author(s):  
Nanret Kyeswet Suchi ◽  
Haruna Isa Mohammed ◽  
Adegbite Olutunde Ademola ◽  
Pennap Grace Rinmecit

Aims: This study was conducted to determine the parallel and concurrent infection of dengue virus and Plasmodium falciparum among patients with febrile illnesses attending Bingham University Health Centre, Karu, Nigeria. Study Design: The study was a cross sectional study. Place and Duration of Study: Department of Medical Microbiology and Parasitology, Jos University Teaching Hospital, Jos, Department of Microbiology, Nasarawa State University, Keffi and 68 Nigerian Army Reference Hospital, Yaba-Lagos, between February and July 2017. Methodology: Blood samples were collected from 400 patients with febrile illnesses at the University Health Centre. The resulting sera was screened for dengue virus seromarkers (IgM, IgG and NS1) using Aria Dou dengue virus RDT kits (CTK Biotech, Inc, San Diego, USA) while malaria parasitemia was detected by Giemsa stained thick and thin film microscopy. Data collected were analysed using Smith’s Statistical Package (version 2.8, California, USA) and P value of ≤ 0.05 was considered statistically significant. Results: Of the 400 patients screened, 12(3.0%) were positive for dengue virus, 20(5.0%) for malaria parasite while 10(2.5%) for dengue/malaria co-infection. Infection with dengue virus and malaria parasite was found to be higher among female subjects aged ≤30 years. However, age and gender were not significantly associated with both infections in this study (P > 0.05). Conclusion: Our findings confirmed the presence of dengue virus infection in the study area which probably may have been misdiagnosed and mistreated. Hence, differential diagnosis of febrile illnesses should not only be limited to malaria and typhoid as is always the case in our health care centres.

Objective: This study was carried out to determine the prevalence of microdontia among patients undergoing orthodontic treatment. Materials and Methods: This was a cross-sectional study conducted at Sindh Institute of Oral Health Sciences, (JSMU) from January-2020 to May-2020. Pre-treatment casts were taken of 140 subjects. The mesiodistal dimension of each tooth was recorded through the vernier caliper. Frequency and percentage were calculated for the presence of microdontia. The test applied was Pearson’s Chi-square test to assess the relationship between microdontia and variables like age and gender. P-value <0.05 was taken as statistically significant. Data analysis was performed on SPSS version 22. Results: A total of 140 subjects were selected i.e. 105 (75%) females and 35 (25%) males aged range 13 -30 years with mean age 18.29 ± 3.88. Out of 42, single tooth microdontia was found in 3 (7.1%), more than one tooth microdontia, and generalized microdontia was present in 36 (85.7%) and 3 (7.1%) respectively. Microdontia was found to be more common in the maxilla (n=42, 100%) than the mandible (n=14, 33.3%). It was found more common in females (n=37, 35.2%) as compared to males (n=5, 14.3%). Statistically significant relationship was found among gender and prevalence of microdontia (p=0.019) with a statistically insignificant relationship between age and presence of microdontia (p=0.228). Conclusions: Microdontia was found to be a frequent dental anomaly, was more common in maxilla and females with a significant association with gender.


Author(s):  
Oluwaseun Oladapo Akinyemi ◽  
Babatunde Ayeni ◽  
Olayinka Stephen Ilesanmi ◽  
Oluwatomi Owopetu

Objective: The management of Diabetes Mellitus (DM) is long-term and can be expensive. This study aimed to describe access to anti-diabetic medicines among patients in tertiary health care facilities in Oyo State, Nigeria. Materials and Methods: This was a hospital-based cross-sectional study. The study sites were the University College Hospital (UCH), Ibadan, and Ladoke Akintola University Teaching Hospital, Ogbomosho. It was conducted among 366 diabetic patients who had been attending the endocrinology clinic of these two tertiary health institutions for at least one year. Data analysis was done with the Statistical Program for Social Sciences. Results: Female participants were 186 (50.8%) and 298 (85.6%) depended on close relatives to purchase their drugs. Those who had difficulties affording their anti-diabetic medications were 142 (38.8%) and 80 (56.3%) preferred buying a cheaper brand of anti-diabetic medication. Also, 136 (37.2%) respondents had missed their required drugs at some point due to insufficient funds. Males who were able to afford their anti-diabetic medication were 96 (53.3%) compared to 128 (68.8%) females (P-value= 0.002). Those with no formal education had the highest proportion of respondents who could not easily afford anti-diabetic drugs (60.9%), those with tertiary education had the highest proportion of respondents who could afford their medication (77.5%), (P-value=< 0.001). Among those in the 61-70 years age group, 78 (66.1%) achieved glycaemic control compared to 34 (42.5%) of those above 70 years (P-value=< 0.001). Conclusion: To improve affordability, subsidizing the cost of anti-diabetic medications and encouraging patients to enrol in the Health Insurance Scheme will be beneficial.


2021 ◽  
Vol 12 (2) ◽  
pp. 327
Author(s):  
Ikit Netra Wirakhmi ◽  
Iwan Purnawan

AbstrakLatar belakang: Sampai saat ini, hipertensi masih merupakan tantangan besar di Indonesia. Kepatuhan pasien dalam menggunakan obat berpengaruh terhadap keberhasilan terapi pengobatan. Adanya ketidakpatuhan pasien hipertensi dalam minum obat dapat memberikan efek negative yang sangat besar, seperti munculnya komplikasi. Tujuan: Mengetahui hubungan kepatuhan minum obat dengan tekanan darah pada penderita hipertensi di Puskesmas Karangjambu Kabupaten Purbalingga. Metode: Desain penelitian ini adalah cross sectional study. Responden dalam penelitian ini adalah pasien hipertensi di Puskesmas Karangjambu Kbupaten Purbalingga. Sampel diambil menggunakan teknik accidental sampling dengan jumlah 86 responden. Data dikumpulkan pada bulan Mei 2021 menggunakan kuesioner 8 – Item Morisky Medication Aderence Scale (MMAS – 8) dan pengukuran tekanan darah secara langsung. Hasil: Penelitian ini menunjukkan bahwa Sebagian besar responden adlaah perempuan (86%), sebgain besar berada pada kategori tingkat kepatuhan sedang (47%) dan pada kategori hipertensi tahap 2 (63%). Uji stastistik didapatkan nilai p value 0.901 menunjukkan bahwa tidak ada hubungan kepatuhan minum obat dengan tekanan darah pada penderita hipertensi. Kesimpulan: Tidak ada hubungan kepatuhan minum obat dengan tekanan darah pada penderita hipertensi AbstractBackground: In Indonesia, hypertension is still a major problem. Adherence to treatment is critical for hypertension patients' long-term health and well-being. Adherence are required for hypertension therapy to be effective, and altering these patients' behavior has the greatest potential for improving hypertensive control. Objectives: To explore the relationship between medication adherence and blood pressure in hypertension patients. Methods: We used the cross-sectional study. This research sample was hypertension patients at Karangjambu Health Centre Purbalingga Regency. We included 89 respondents by accidental sampling technique. We collected the data by questionnaire. The Gamma & Sommers’d test was performed to analyze the data. Results: This research showed that that the majority of respondents were women (86%), the moderate category had the highest level of adherence (47%) and the most respondents suffer from hypertension stage 2 (63%). The statistical test result of 0.910 suggested that there was no relationship between medication adherence and blood pressure in hypertensive patients. Conclusions: There was also no significant between medication adherence and blood pressure. 


2017 ◽  
Vol 15 (9) ◽  
pp. 637-643
Author(s):  
Manas KOTEPUI ◽  
Bhukdee PHUNPHUECH ◽  
Nuoil PHIWKLAM ◽  
Kwuntida UTHAISAR

Malaria caused by Plasmodium vivax has placed huge burdens on the health, longevity, and general prosperity of large sections of the human population. In this study, the clinical profiles of patients infected with P. vivax in western Thailand were analyzed. A retrospective cross-sectional study of malaria cases resulting in hospitalization between 2013 and 2015 was collected. Clinical characteristics, diagnoses, and parasitological results on admission, age, and gender were mined from medical records at the laboratory unit, Phop Phra Hospital, located in endemic areas of Tak Province, Thailand. The results revealed that patients infected with P. vivax (276 cases) showed high monocyte counts during the initial stage of infection and continuously lower counts during the later stage of infection (p = 0.021). Low basophil counts during the initial stage of infection and continuously higher counts during the later stage of infection were also found (p = 0.033). Patients with many stages of P. vivax showed lower lymphocyte and basophil counts (p value = 0.011, 0.01), respectively. In conclusion, this study indicated the hematological alteration of patients infected with P. vivax. Alterations of monocyte and basophil counts during different stages of P. vivax infection were frequently found. In addition, many stages of P. vivax in the blood of patients were associated with lower lymphocyte counts. This information contributes to a better understanding of the pathological characteristics of P. vivax infection.


2015 ◽  
Vol 22 (01) ◽  
pp. 072-075
Author(s):  
Sana Zulfiqar ◽  
Amin Fahim ◽  
Aneela Qureshi ◽  
Sadia Adnan ◽  
Shomail Saeed Siddiqui ◽  
...  

Objective: To find out the Modified Marsh type of celiac disease (CD)patients on histopathological examination of duodenal (D2) biopsies and to correlate it withtissue transglutaminase IgA levels. Study Design: Cross sectional study. Place of Study:Histopathology laboratory (Department of Pathology), Isra University Hospital and AsianInstitute of Medical Sciences (AIMS), Hyderabad. Duration of Study: July 2013 to December2013. Materials and Methods: 96 patients with a history of malabsorption or atypical symptomswith clinical suspicion of CD were subjected to endoscopy. Endoscopic duodenal (D2) biopsieswere taken regardless of age and gender. D2 biopsies were processed for histopathologicalexamination under light microscopy. Results: Out of 96 patients, 45 (46.9%) patients hadmoderate type of lamina propria inflammation along with highly significant p-value (0.0001).CDtype 3a was observed in 34 patients (35.4%). In this study the comparison of serological level oftissue Transglutaminase IgA (tTGA) and histological severity revealed significant correlation. AllModified Marsh types of CD with tTGA level seen in our study were highly significant (p-value0.001). Conclusion: In this study strong correlation was observed between the serologicaltTGA level and histological findings by Modified Marsh classification along with lamina propriainflammation of duodenal mucosa in CD patients.


Author(s):  
Jafer Siraj ◽  
Turi Abateka ◽  
Oliyad Kebede

Introduction: A number of medications have been demonstrated to lower blood glucose. However, current-day management has failed to achieve and maintain the optimal glycemic level for diabetic patients. Patients’ non-adherence is among the most contributing factors. Therefore, the aim of this study was to explore the prevalence of non-adherence to anti-diabetic medications and associated factors. Methods: A hospital based cross-sectional study was conducted from November 2020 to January 2021. A systematic random sampling technique was used. Data were collected by structured questionnaire adapted from different literatures. Then, data were entered into SPSS version 25 and analyzed. To determine the association of dependent and independent variables, multiple logistic regression was done. P-value <.05 was considered statistically significant. Results: A total of 275 study participants were interviewed with a response rate of 100%. From this 53.8% were females, 59.3% were in the age group of 41-60 years, 35.3% were college/university graduates and 79.3% were not using social drugs. One hundred eighty-seven (68%) of them were adherent to their anti-diabetic medication. Factors found to be significantly associated with anti-diabetic medication adherence were age >60 years (AOR = .276, 95% CI = .124-.611) attending higher education (AOR = 6.203, 95% CI = 1.775-21.93), retired (AOR = 7.771, 95% CI = 1.458-41.427), housewife (AOR = 7.023, 95% CI = 1.485-33.215), average monthly income 1001birr-2000 birr (AOR = .246, 95% CI = .067-.911) and social drug use (AOR = 3.695, 95% CI = 1.599-8.542). Forgetfulness, not affording, side effects, misunderstanding of instructions, and poly-pharmacy were identified reasons for non-adherence. Conclusions and Recommendations: Patients’ adherence to anti-diabetic medications in the current study is sub-optimal. Age, monthly income, level of education, occupational status, and social drug use were associated with adherence. Forgetfulness, not affording, and side effects were reasons identified to contribute to non-adherence. Therefore, adherence counseling, use of alarms, and the way to mitigate non-affordability, including anti-diabetic medications into a program drug should be considered.


Author(s):  
Tolulope O. Afolaranmi ◽  
Zuwaira I. Hassan ◽  
Joy L. Mbak ◽  
Davou W. Luka ◽  
Takzhir N. Audu ◽  
...  

Background: Compliance with prescribed treatment and retention in care are key components in the management of chronic diseases which is vital in averting the long term complications that could arise from such conditions. Failure to comply with treatment recommendations is often associated with poor retention in care. In view of this, this study was conducted to determine the level of treatment compliance and retention in care among patients with hypertension and diabetes in Jos University Teaching Hospital.Methods: This was a cross sectional study conducted among 290 eligible respondents between September and November 2017 using quantitative method of data collection. SPSS version 20 was used for data analysis with adjusted odds ratio and 95% confidence interval used as point and interval estimates while p-value of ≤0.05 was considered statistically significant.Results: The mean age of the respondents was 54.5±13.1 years with 43.8% of the respondents found to have satisfactorily complied with prescribed treatment while 117 (40.3%) were uninterruptedly retained in care within the last 6 months' clinic appointments  prior to the study.Conclusions: This study has demonstrated the levels of compliance with treatment and retention in care bringing to bear the need to provide structured interventions targeted at attaining improvement in compliance with treatment and retention in care among individuals on long term care.


2020 ◽  
Vol 1 (2) ◽  
pp. 30-41
Author(s):  
Maryam Moula Maryam Moula ◽  
Muhammad Akram Sharif ◽  
Faraz A. Wajidi

To determine employee autonomous motivation and find out the effect of age and Gender on autonomous motivation among employees working in public sector medical university, Karachi. A Cross-sectional study design was used to conduct this study among employees of public sector medical university. The duration of the study was three months. The sample size of the study was 384. The response rate was 78%, 300 out of 384 duly filled questionnaires were collected. A probability random sampling technique was used to collect data. SPSS software was applied to analyze the collected data. Mean ±SD and % & n were explored for Quantitative and Qualitative variables, respectively. T-Test and one-way ANOVA were applied to test hypotheses. P-Value <0.05 was considered significant. 59.3% (n=178) were males. 46% (n=138) were females in age between 25 to 31 years. 53.7 % (n=161) respondent reported their marital status as single. The mean age of the respondents was 30.16±7.03. Factors that motivate employees included salary (34%), positive feedback (26.3%), felt very proud when did well at work (52%), learnt new things (57.7%), , had a feeling of accomplishment (35.3%), Solving work issues made them feel important (26.7%), felt guilty if didn’t accomplish a job-related task (45.3%). The t-test and ANOVA revealed significant effect of gender; t (298) = -2.81, p-value = 0.005, CI [-3.77, -0.66] and age; F (5,294) =2.56, p-Value = 0.027 on employees’ autonomous motivation. It was observed proven that there was a significant effect of gender and age on employee’s autonomous motivation.


2021 ◽  
Vol 4 (2) ◽  
pp. 365-370
Author(s):  
Baseem Natheer Abdulhadi ◽  
Ali Ibrahim Shyaa ◽  
Laith ALTamimi

Background: Among the most popular methods employed to classify the depth of the olfactory fossa is Keros classification. This study aims to assess Keros classification of the ethmoid roof, any possible association between Keros types and gender, and the incidence of asymmetry between right and left sides among Iraqi patients.  Methods: A retrospective cross-sectional study was conducted at Al-Shaheed Gazi Al-Hariri Teaching Hospital, Medical City, Baghdad, Iraq. The archived reports and the CT scans images (nose and paranasal sinuses) of 126 patients who have undergone functional endoscopic sinus surgery between January 2019 and January 2020 were reviewed. Univariate and bivariate statistical analysis was performed using SPSS version 24. The statistically significant was considered at less than 0.05. Results: More than half of patients were females (54.0%) with a mean age of 31.52 ± 11.38 (SD) years (range: 10-57 years). Among the total patients, the mean depth of olfactory fossa (OF) was 3.58 ± 0.02 mm. Results showed that Keros type I was the most common type (71.0%), followed by type II (27.4%) and type III (1.6%) respectively. The difference in the olfactory fossa depth between the right and left sides was ≥ 1 mm in 16 (12.7%) patients and < 1 mm in 110 (87.3%) patients. Moreover, there was no significant relation between symmetry/asymmetry and gender ( p-value > 0.05). Conclusion: Keros type I was the most common type, which carries the lowest risk of inadvertent intracranial injury during endoscopic sinus surgery; besides the relatively low percentage of asymmetry in the depth of the two olfactory fossae among patients, surgeons should always be cautious during surgery to avoid iatrogenic injury concerning the thin lateral lamella of the cribriform plate.


2021 ◽  
Author(s):  
◽  
Elbagir Mustafa ◽  
Mohamed Abdulkarim ◽  
Khalid A. Awad ◽  
Alaa Osman Mohamed Koko

Abstract Background: Measurements of the normal portal venous dimension in a specified population is so crucial. portal vein can be measured by several methods for assessing different parameters, Computed topography (CT) and sonographic imaging are common examples. The diagnosis of portal hypertension depends on the transverse portal vein diameter (normal diameter from 6-15 mm). The aim of this study is to establish baseline value for the portal vein diameter and assess the correlation with age, gender, weight, height and BMI in Sudanese populations.Methodology: This was a descriptive cross-sectional study that included a sample of Sudanese adults who were requested to have routine abdominal sonographic scanning due to reasons not related to liver or portal vein problems. The study was carried out at the Radiology Department of Qatar Alnada Hospital, Umbadda, Khartoum, Sudan 2020.Results: In this study, 376 participants were included of which more than half were females (56.1%, n=211), while 165(43.9%) were males. The mean age of the participants was 38.12 + 15.57 years. The mean portal vein diameter was 10.79 + 1.27 millimeters. From this study the portal vein diameter varied with age (p value = 0.000), weight (p value = 0.002), height (p value = 0.000) and gender (p value = 0.000). It is not related to BMI (p value = 0.3).Conclusion: This study has revealed that the portal vein diameter has positive correlation with age, gender, height, and weight of the person and has no correlation with the BMI.


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