scholarly journals The Potential Pharmacological and Medicinal Properties of Neem (Azadirachta indica A. Juss) in the Drug Development of Phytomedicine

2019 ◽  
pp. 1-18 ◽  
Author(s):  
E. A. Tembe-Fokunang ◽  
Fokunang Charles ◽  
Nubia Kaba ◽  
Gatsing Donatien ◽  
Agbor Michael ◽  
...  
Keyword(s):  
Azadirachta Indica ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Low Cost ◽  
Local Population ◽  
Herbal Product ◽  
Medicinal Uses ◽  
Active Chemical ◽  
Medicinal Properties ◽  
Insight Into

An understanding of the chemistry of the secondary metabolites of neem plant (Azadirachta indica A. Juss) is essential and important due to its medicinal properties. Several studies have been done on the biological and pharmacological activities with a considerable progress made with respect to its biological activity and medicinal uses. The neem safety is known from its long communal ethno-pharmacological uses as a category one herbal product. It is readily available with great access to the local population at low cost and environmentally friendly. This paper attempts to give an insight into the biological activities of some of the compounds isolated, pharmacological actions of the extract, clinical studies and medicinal applications along with their safety evaluations. Issues on the active chemical constituents of various formulations, commercially available neem products, are also mentioned along with their respective application.

A Review of Phytochemical and Pharmacological Studies of Inula Species

2020 ◽  
Vol 16 (5) ◽  
pp. 557-567
Author(s):  
Aparoop Das ◽  
Anshul Shakya ◽  
Surajit Kumar Ghosh ◽  
Udaya P. Singh ◽  
Hans R. Bhat
Keyword(s):  
Bacterial Infections ◽  
Chemical Constituents ◽  
Valuable Insight ◽  
Important Ingredient ◽  
Pharmacological Activities ◽  
Medicinal Uses ◽  
The Family ◽  
Pharmacological Studies ◽  
Perennial Herbs ◽  
Insight Into

Background: Plants of the genus Inula are perennial herbs of the family Asteraceae. This genus includes more than 100 species, widely distributed throughout Europe, Africa and Asia including India. Many of them are indicated in traditional medicine, e.g., in Ayurveda. This review explores chemical constituents, medicinal uses and pharmacological actions of Inula species. Methods: Major databases and research and review articles retrieved through Scopus, Web of Science, and Medline were consulted to obtain information on the pharmacological activities of the genus Inula published from 1994 to 2017. Results: Inula species are used either alone or as an important ingredient of various formulations to cure dysfunctions of the cardiovascular system, respiratory system, urinary system, central nervous system and digestive system, and for the treatment of asthma, diabetes, cancers, skin disorders, hepatic disease, fungal and bacterial infections. A range of phytochemicals including alkaloids, essential and volatile oils, flavonoids, terpenes, and lactones has been isolated from herbs of the genus Inula, which might possibly explain traditional uses of these plants. Conclusion: The present review is focused on chemical constituents, medicinal uses and pharmacological actions of Inula species and provides valuable insight into its medicinal potential.

scholarly journals The Physicochemical analysis and Phytochemical screening of some medicinal plants of Letang Municipality of Morang district, Nepal

BIBECHANA ◽  
2020 ◽  
Vol 17 ◽  
pp. 67-74
Author(s):  
Narendra Kumar Chaudhary ◽  
Rijan Ojha ◽  
Tilak Prasad Gautam
Keyword(s):  
Medicinal Plants ◽  
Chemical Constituents ◽  
Powdered Material ◽  
Physicochemical Analysis ◽  
New Drugs ◽  
Phytochemical Analysis ◽  
Plumbago Zeylanica ◽  
The People ◽  
Active Chemical ◽  
Medicinal Properties

Ethnobotany gives the basic idea about the medicinal properties of plants. Identification of active compounds of the medicinal plants and their standardization is essential for the production of new drugs. In the present work, different parts of the five medicinal plants (Curcuma caesia, Costus speciosus, Drymaria cordata, Leea macrophylla, Plumbago zeylanica) were washed, air dried and crushed. Three different extracts of each powdered material were prepared and standard phytochemical analysis procedure was followed for the analysis of physicochemical properties of plants and the identification of active chemical constituents. Among 5 plants, the highest moisture content (14.83%) was found in Plumbago zeylanica, higher total ash (9.22%) and acid insoluble ash (4.43%) were observed in Cucurma caesia. Phytochemical analysis revealed the presence of 12 varieties of bioactive chemicals in the 5 different plants. The plants of the area have great diversity of phytochemicals of numerous medicinal properties. In conclusions, these five important medicinal plants could be useful for the people of the locality to cure several diseases as well as to generate the source of income. BIBECHANA 17 (2020) 67-74

scholarly journals Apple Pomace as Potential Source of Natural Active Compounds

Planta Medica ◽  
2017 ◽  
Vol 83 (12/13) ◽  
pp. 994-1010 ◽  
Author(s):  
Katharina Waldbauer ◽  
Ruxandra McKinnon ◽  
Brigitte Kopp
Keyword(s):  
Manufacturing Industry ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Low Cost ◽  
Waste Product ◽  
Extraction Methods ◽  
Apple Pomace ◽  
Current Evidence ◽  
Apple Industry ◽  
Antiviral Effects

AbstractApple pomace is a waste product of the apple manufacturing industry that has been in the focus of life sciences as it represents a low-cost source of fruit-derived compounds. High fruit consumption is associated with beneficial health effects, and therefore, apple pomace and its constituents raise therapeutic interest. The present work reviews (i) the chemical constituents of apple pomace, (ii) optimized extraction methods of apple pomace compounds, and (iii) biological activities of apple pomace. Current evidence of apple pomace influence on digestion and metabolism, cholesterol and triglyceride homeostasis, diabetes, and sex hormones is summarized. Furthermore, studies regarding its antioxidative, anti-inflammatory, antiproliferative, antibacterial and antiviral effects are presented. The review concludes that apple pomace is an underutilized waste product of the apple industry with the potential of being processed for its nutritional and pharmaceutical value.

scholarly journals Gmelina arborea: chemical constituents, pharmacological activities and applications

2017 ◽  
Vol 9 (4) ◽  
pp. 528 ◽  
Author(s):  
Charu Arora ◽  
Vinita Tamrakar
Keyword(s):  
Biological Activities ◽  
Chemical Constituents ◽  
Iridoid Glycoside ◽  
Immunomodulatory Activity ◽  
Gmelina Arborea ◽  
Β Cells ◽  
Pharmacological Activities ◽  
Flavone Glycoside ◽  
Ancient Times ◽  
Medicinal Properties

<p><em>Gmelina arborea </em>(<em>G. arborea</em>) is a bio-prospective plant belonging to family verbenaceae. It is widely used for it’s medicinal properties from ancient times. The present paper comprehensively reviewed the traditional uses, medicinal properties and chemical constituents isolated from <em>G. arborea</em> based on literature reported as well as critical analysis of the research. The present article is aimed to provide information on recent advances and new foundations and direction for further exploring <em>G. arborea </em>for its applications. Pharmacological research reviewed that <em>G. arborea </em>possess various medicinal properties and biological  activities including antidiuretic, antidiarrhoeal, antipyretic, antianalgesic, antioxidant, antidiabetic, antihelmintic, antibacterial, antifungal, cardiopotective, insecticidal, antiulcer, gastro-protective, anticancer, antihyperlipidemic and immunomodulatory activity. It has been reported for its applications in treatment of bone fracture, hypertension and regeneration of β-cells. The main chemical constituents of <em>G. arborea</em> include lignans, iridoid glycoside, flavonoids, flavons, flavone glycoside and sterols. The present review provides all the references and beneficial directions to explore further application of <em>G. arborea.</em></p>

Review: Phytochemicals of the Seriphidium, Economically and Pharmaceutically Important Genus of Asteraceae Family

2020 ◽  
Vol 17 (2) ◽  
pp. 158-168
Author(s):  
Nusrat Shafiq ◽  
Sahrish Shafiq ◽  
Naila Rafiq ◽  
Shagufta Parveen ◽  
Irum Javed ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Local Communities ◽  
Review Article ◽  
Pyridine Derivatives ◽  
Biological Potential ◽  
Medicinal Properties ◽  
Phenolic Derivatives ◽  
Asteraceae Family

Seriphidium plants were reported to be utilized by local communities to cure their ailments in the form of paste, tincture, tea, nutraceuticals due to their medicinal properties. Most of the species are used as food, forage and ornamentals, etc. Due to the significant properties of the Seriphidium plants, the present article was designed to compile the data of major aspects and chemical constituents of genus Seriphidium responsible for their significant uses. This review article comprehensively covers the biological potential of different plants with their secondary metabolites and describes an overview of the biological activities of the different species belonging to genus Seriphidium. The main secondary metabolites isolated from different species of the genus Seriphidium are triterpenoid, sesquiterpenes, flavonoids, coumarins, chromones, anthraquinones, polyphenols and their glycosides, phenolic derivatives, balchanins, costunolides, Vulgarin, pyridine derivatives, ceramides, biphenyls, isoflavones. All these compounds are used in the drug industry.

Antimicrobial agent from Plants and Herbs: A systemic Review

2021 ◽  
pp. 179-181
Author(s):  
Sherekar P. P.
Keyword(s):  
Medicinal Plants ◽  
Chemical Constituents ◽  
Infectious Agent ◽  
Herbal Product ◽  
Systemic Review ◽  
Microbial Infection ◽  
Happy Life ◽  
Active Chemical ◽  
Wide Range ◽  
Crude Drugs

The whole worldwide, now a days use many herbal product for healthy and happy life. In ancient system there are Ayurveda Siddha, Unani and Homoeopathy systems of medicines includes various different herbs, crude drugs, medicinal plants. Many ayurvedic herbs are known for its important medicinal property. Medicinal plants are mostly used for wide range of constituent present in it. In Ayurveda system of medicine, antimicrobial herbs find to be used in many ayurvedic preparations. Various antimicrobial herbs have been used against different microbial infection like bacteria, virus, fungi protozoa, helminths etc. and many more different infectious agent of different diseases. The active chemical constituents present in herbs or crude drug or medicinal plants inhibits the growth of microorganisms. The present attempt has been made to review studied various antimicrobial herbs.

Qualitative and Quantitative Phytochemical Screening of Azadirachta indica Juss. Plant Parts

2021 ◽  
Vol 9 (2) ◽  
pp. 122-127
Author(s):  
Sujata Khanal
Keyword(s):  
Secondary Metabolites ◽  
Azadirachta Indica ◽  
Wide Spectrum ◽  
Chemical Constituents ◽  
Gravimetric Method ◽  
Stem Bark ◽  
Plant Parts ◽  
Synthetic Chemicals ◽  
Active Chemical ◽  
Quantitative Screening

Azadirachta indica which is commonly known as neem plant has one of the most promising medicinal properties having a wide spectrum of biological activity. Fresh matured leaves, stem-bark and seeds of A. indica (neem) were collected, air dried and aqueous-extract was used to screen for some active chemical constituents. Phytochemicals of neem plant parts were extracted and screened both qualitatively and quantitatively. The screening of A. indica was carried out at Institute of Agriculture and Animal Science, Paklihawa Campus, Rupandehi in a quest to evaluate the phytochemicals. Among the qualitative tests done for the presence of secondary metabolites; alkaloids, saponins, terpenoids, flavonoids were found to present in all of the tested parts whereas steroids, polyphenols and tannins were present only in leaves and stem-bark. Glycosides and coumarins are absent in all of the tested parts. Quantitative screening was also done by using gravimetric method. Alkaloids were found in all the parts of A. indica with the highest amount of alkaloids were obtained in stem-bark (12.8%) and lowest in leaves (10.67%). Highest flavonoids percentage was revealed in leaves (13.8%) and lowest flavonoids in stem-bark (12.8%). Similarly, seeds (2.53%) contained saponins % while it was lowest in stem-bark (2.50 %). Terpenoids % were similar in both i.e. leaves and stem-bark (13.13%), whereas lowest in seeds (12.77%). More research on secondary metabolites will be helpful to the chemical industries to produce plant-based chemicals and minimize the environment degradation from different synthetic chemicals. Int. J. Appl. Sci. Biotechnol. Vol 9(2): 122-127.  

Technological Aptitudes and Pharmaceutical Applications of Schinus terebinthifolius Raddi Leaf and Seed Oil and Fruit Powders of Ziziphus jujuba Mill

2018 ◽  
Vol 18 (5) ◽  
pp. 305-313 ◽  
Author(s):  
A. Benahmed Djilali ◽  
C. Besombes ◽  
K. Allaf ◽  
M. Nabiev
Keyword(s):  
Seed Oil ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Local Population ◽  
Industrial Applications ◽  
Bioactive Substances ◽  
Air Drying ◽  
Schinus Terebinthifolius ◽  
Ziziphus Jujuba ◽  
Physical And Chemical

This study is aimed at describing, controlling, and improving the technological aptitude and the traditional pharmacopeia of Schinus terebinthifolius Raddi conventionally used by the local population of Tizi-Ouzou (northern Algeria) and justifying the possible industrial applications of the plant. The study involved the drying of Schinus terebinthifolius Raddi leaves using two types of drying process (hot air drying and open air drying). In addition, the evaluation of certain properties (physical and chemical, rheological and biological) of the obtained powders was carried out. Various gels were prepared using the powders of air-dried Schinus terebinthifolius Raddi leaves, DIC (instant controlled pressure-drop) swell-dried Ziziphus jujuba Mill fruits, and seed oil of the same fruit. These plants have been used traditionally for treating gastric disorders, wounds, and rheumatic pains. Schinus terebinthifolius Raddi is also used as an antiseptic and antihelmintic agent. The results of the analysis of Schinus terebinthifolius Raddi powders have shown important chemical constituents (Na, Mg, Fe, and K), bioactive substances (polyphenols, tannins, and fatty acids), and very interesting biological activities. The obtained gels confer better physical and chemical (slightly acidic gels) properties, a higher availability of phenolic compounds, and better rheological (viscous gel) and organoleptic properties than their chemical counterparts.

scholarly journals Phytochemicals and Medicinal Properties of Indigenous Tropical Fruits with Potential for Commercial Development

2016 ◽  
Vol 2016 ◽  
pp. 1-20 ◽  
Author(s):  
Hock Eng Khoo ◽  
Azrina Azlan ◽  
Kin Weng Kong ◽  
Amin Ismail
Keyword(s):  
Biological Activities ◽  
Radical Scavenging ◽  
Limited Information ◽  
Tropical Fruits ◽  
Commercial Development ◽  
Medicinal Uses ◽  
Developmental Potential ◽  
Medicinal Properties

Hundreds of fruit-bearing trees are native to Southeast Asia, but many of them are considered as indigenous or underutilized. These species can be categorized as indigenous tropical fruits with potential for commercial development and those possible for commercial development. Many of these fruits are considered as underutilized unless the commercialization is being realized despite the fact that they have the developmental potential. This review discusses seven indigenous tropical fruits from 15 species that have been identified, in which their fruits are having potential for commercial development. As they are not as popular as the commercially available fruits, limited information is found. This paper is the first initiative to provide information on the phytochemicals and potential medicinal uses of these fruits. Phytochemicals detected in these fruits are mainly the phenolic compounds, carotenoids, and other terpenoids. Most of these phytochemicals are potent antioxidants and have corresponded to the free radical scavenging activities and other biological activities of the fruits. The scientific research that covered a broad range ofin vitrotoin vivostudies on the medicinal potentials of these fruits is also discussed in detail. The current review is an update for researchers to have a better understanding of the species, which simultaneously can provide awareness to enhance their commercial value and promote their utilization for better biodiversity conservation.

scholarly journals A Review of Common Medicinal Plants in Chin State, Myanmar

2018 ◽  
Vol 13 (11) ◽  
pp. 1934578X1801301
Author(s):  
Zaw Min Thu ◽  
Mya Mu Aye ◽  
Hnin Thanda Aung ◽  
Myint Myint Sein ◽  
Giovanni Vidari
Keyword(s):  
Medicinal Plants ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Therapeutic Effects ◽  
Medicinal Uses ◽  
The People ◽  
Natural Remedies ◽  
Phytochemical Constituents ◽  
Croton Oblongifolius ◽  
Myrica Nagi

Promising sources of novel bioactive compounds include plants growing in several third-world countries where the local flora is still largely uninvestigated. A paradigmatic example is represented by medicinal plants growing in Myanmar, especially in Chin State, in northwestern Myanmar. This is one of the least developed areas of the country where the people still use natural remedies derived from a rich biodiversity. This review mainly covers the investigations done on phytochemical constituents and biological activities of 20 medicinal plants, namely Alangium chinense, Anemone obtusiloba, Anneslea fragrans, Antidesma bunius, Croton oblongifolius, Embelia tsjeriam-cottam, Ficus heterophylla, Gaultheria fragrantissima, Hydnocarpus kurzii, Leea macrophylla, Leucas cephalotes, Millingtonia hortensis, Myrica nagi, Olax scandens, Pimpinella heyneana, Pterospermum semisagittatum, Ruellia tuberosa, Smilax zeylanica, Stemona burkillii, and Tadehagi triquetrum, that have long been used in the Chin State for curing various diseases. These plants have been selected on the basis of their medicinal uses not only in Myanmar but also in the related Ayurvedic healing system. Moreover, besides their medicinal importance, most of them grow in the Chin State more abundantly than in other regions of Myanmar. Although the efficacy of some of these plants have been verified scientifically, the chemical constituents and biological activities of most of them still need to be investigated to confirm the claimed therapeutic effects.

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