The formation and development of pediatrics and pediatric education in Primorye

The article presents historical information about the development of pediatrics and pediatric education in Primorsky Region. It started from the establishment of the pediatric faculty of the Vladivostok Medical Institute in 1969 to the present day. Main directions of scientific and pedagogical activities of pediatric profile departments are highlighted. The departments were reorganized in 2016 into the Institute of Pediatrics; departments of normal and pathological physiology, pathological anatomy, and foreign languages. The article also indicates those people who were at the origins of pediatrics and pediatric education in Primorye.

New aspects of pedagogical activity in the distant form of pathological physiology teaching to medical university students

Distance learning (DL) is a completely new and unique form of education, which got forced to switch to by the current pandemic of coronavirus disease. Note that until now, distance learning technologies have been used at the department of general and clinical pathological physiology and some other departments of the Odessa National Medical University (ONMedU). The aim of this analytical article is to analyze the efficacy of ONMedU General and Clinical Pathological Physiology Department staff during the one and a half year period of the coronavirus infection pandemic with an accent to psychological approach to students modified teaching. The urgent need of time and the primary desire to protect students and their own lives during 2020-2021 requires us to improve our own pedagogical approaches in the further on-line teaching of students. We see success in systematic methodological work with students, the implementation of which will make it possible to evoke and increase their motivation to study histology. The importance of this methodological technique, supported in the senior years of medical universities by the integration of teaching theoretical and clinical disciplines, the approximation of teaching to specific clinical cases will help optimize the assimilation of morphological knowledge by students at least and, undoubtedly, in the near future will lead to a better assimilation of clinical disciplines. In connection with the ideas of individualized and developmental learning, the use of psychological capabilities of learning tools in the virtual environment brings both pedagogy and psychology to a new level of understanding the mediation of mental, creative, communicative and executive learning and learning activities. The use of distance learning helps the students to acquire skills of independent work, creates comfortable conditions for creativity, increases the creative and intellectual potential of the student through self-organization, the ability to interact with computer technology and make responsible decisions, creates favorable conditions for individual creative expression in the process of learning, for the development of the student's personality. The authors are convinced that the optimization and improvement of the educational process in medical universities is to draw students' attention to the problems that the medical community is dealing with on a daily basis today.

Academician Andrei Dmitrievich Ado and the Kazan Scientific Research Institute of Epidemiology and Microbiology

The article was prepared for the 120th anniversary of the Kazan Scientific Research Institute of Epidemiology and Microbiology and the 110th anniversary of the birth of the academician, laureate of the USSR State Prize, the author of fundamental guidelines on allergology and pathological physiology, an honorary member of scientific societies of many countries Andrei Dmitrievich Ado who is a representative of the famous dynasty of scientists and doctors of Mislawski-Ado. The paper presents materials about the dynasty A.A. Mislavsky, N.A. Mislavsky, A.N. Mislavsky and others; information about the Kazan period of A.D. Ado between 1938 and 1952 during his work at Kazan Scientific Research Institute of Epidemiology and Microbiology (Kazan Institute of Epidemiology and Microbiology until 1942). The article was prepared using documents from the archives of Kazan Scientific Research Institute of Epidemiology, Microbiology, Kazan Medical University, memoirs of their colleagues.

Myocardial reperfusion syndrome. Pathogenesis, clinic, diagnosis

The basics of pathogenesis, clinic and diagnosis of myocardial reperfusion syndrome are considered. Myocardial reperfusion syndrome is defined. Its relevance as one of the most poorly studied and formidable complications of cardiac reperfusion in myocardial infarction with elevation of the S-T segment has been explained. A brief review of the historical review of this problem and such types of manifestations of myocardial reperfusion syndrome as: diastolic myocardial dysfunction, post-reperfusion disturbances of the heart rhythm, the phenomenon of no-reflow and irreversible damage to the myocardium are briefly reviewed. The modern views on the pathological physiology of diastolic myocardial dysfunction, post-reperfusion damage to the myocardium, and the no-reflow phenomenon are analyzed. A review of current views on the pathological physiology of the development of post-reperfusion disturbances in heart rhythm is carried out. The clinical picture and the effect on the hemodynamics of such a manifestation of myocardial reperfusion syndrome as diastolic myocardial dysfunction are described. A brief description of the clinical picture of irreversible post-reperfusion damage to the myocardium is given. The clinical picture and types of post-reperfusion rhythm disturbances are described. The diagnostics of the no-reflow phenomenon has been analyzed in detail, the coronary angiographic scales for assessing thrombolysis in myocardial infarction and for assessing myocardial perfusion are graphically shown. A description of the basics of diagnosing post-reperfusion disturbances in heart rhythm, diastolic myocardial dysfunction, and post-reperfusion irreversible damage to the myocardium is given. A brief description of the known in the world literature predictors of the development of myocardial reperfusion syndrome is presented.

CHARACTERISTICS OF THE TEACHING METHOD OF “PATHOLOGICAL PHYSIOLOGY” TO FOREIGN STUDENTS

One of the parts of “Pathological physiology” teaching taking into account the specifics of the training of foreign students, is development, creation and application of innovative teaching methods in the educational process with the maximum degree of schematization, systematization and visualization of educational material. This contributes not only to the transformation of educational information into students' knowledge and skills, but also to the intensification of the educational process, including cooperative learning methods, game methods with text; associative teaching methods.

Syntheses of Hydrazino-and Azo-Sphingosine Derivatives and Their Evaluation as SphK Inhibitors

Bioactive sphingolipids have been recognized to play important roles in both normal and pathological physiology related to the regulations of cell proliferation, differentiation, survival, trafficking, and cell death. [...]