Letter to the Editor: The Continuing Challenge of Evaluating RSD Impairment and Disability

1998 ◽  
Vol 3 (5) ◽  
pp. 8-10
Author(s):  
Robert L. Knobler ◽  
Charles N. Brooks ◽  
Leon H. Ensalada ◽  
James B. Talmage ◽  
Christopher R. Brigham
Keyword(s):  
Disability Evaluation ◽  
Body Part ◽  
Loss Of Function ◽  
Regulatory Requirements ◽  
Major Cardiac Event ◽  
Clinical Scenarios ◽  
Impairment Score ◽  
Occupational Activities ◽  
The Difference

Abstract The author of the two-part article about evaluating reflex sympathetic dystrophy (RSD) responds to criticisms that a percentage impairment score may not adequately reflect the disability of an individual with RSD. The author highlights the importance of recognizing the difference between impairment and disability in the AMA Guides to the Evaluation of Permanent Impairment (AMA Guides): impairment is the loss, loss of use, or derangement of any body part, system, or function; disability is a decrease in or the loss or absence of the capacity to meet personal, social, or occupational demands or to meet statutory or regulatory requirements because of an impairment. The disparity between impairment and disability can be encountered in diverse clinical scenarios. For example, a person's ability to resume occupational activities following a major cardiac event depends on medical, social, and psychological factors, but nonmedical factors appear to present the greatest impediment and many persons do not resume work despite significant improvements in functional capacity. A key requirement according to the AMA Guides is objective documentation, and the author agrees that when physicians consider the disability evaluation of people, more issues than those relating to the percentage loss of function should be considered. More study of the relationships among impairment, disability, and quality of life in patients with RSD are required.

scholarly journals Tinjauan Kritis Neurosains Terhadap Konsep Qalb Menurut Al-Ghazali

2020 ◽  
Vol 4 (2) ◽  
pp. 70-87
Author(s):  
Muhammad Nasruddin ◽  
Abdul Muiz
Keyword(s):  
Human Brain ◽  
Human Body ◽  
Body Part ◽  
The Body ◽  
Spiritual Intelligence ◽  
Scientific Disciplines ◽  
Different Dimensions ◽  
The Difference ◽  
The Brain

The human body was created very special by God. inside there is a special body part in the form of the brain, and neuroscience is the science that discusses in full the brain from various scientific disciplines. In the study of Islam, qalb is the most important part in the good and bad quality of human faith which is studied in depth in Sufism to the purity of the soul. And Imam Al-Ghazali became one of the Sufi figures who explained in detail about the Qalb. That neuroscience views qalb in Islam as part of the human brain, on the functional basis between the brain and qalb both receive information, spiritual intelligence / qalbiah, spiritual, controlling / coordinating center of the body, and emotional. The brain and qalb, according to Al-Ghazali, both have similarities in the four elements namely controlling the body, knowledge, emotions, and spirituality. And the difference between the two, namely the two different dimensions between the scientific and divine dimensions, so the benchmarks of truth are very different.

Behavioral Factors Impact Impairment and Disability Evaluation

2011 ◽  
Vol 16 (5) ◽  
pp. 5-7
Author(s):  
Lee Ensalada
Keyword(s):  
Social History ◽  
Standardized Test ◽  
Somatoform Disorders ◽  
Disability Evaluation ◽  
Body Part ◽  
Emotional Reactions ◽  
Illness Behavior ◽  
Validity Testing ◽  
Symptom Validity Testing ◽  
Disease Pattern

Abstract Illness behavior refers to the ways in which symptoms are perceived, understood, acted upon, and communicated and include facial grimacing, holding or supporting the affected body part, limping, using a cane, and stooping while walking. Illness behavior can be unconscious or conscious: In the former, the person is unaware of the mental processes and content that are significant in determining behavior; conscious illness behavior may be voluntary and conscious (the two are not necessarily associated). The first broad category of inappropriate illness behavior is defensiveness, which is characterized by denial or minimization of symptoms. The second category includes somatoform disorders, factitious disorders, and malingering and is characterized by exaggerating, fabricating, or denying symptoms; minimizing capabilities or positive traits; or misattributing actual deficits to a false cause. Evaluators can detect the presence of inappropriate illness behaviors based on evidence of consistency in the history or examination; the likelihood that the reported symptoms make medical sense and fit a reasonable disease pattern; understanding of the patient's current situation, personal and social history, and emotional predispositions; emotional reactions to symptoms; evaluation of nonphysiological findings; results obtained using standardized test instruments; and tests of dissimulation, such as symptom validity testing. Unsupported and insupportable conclusions regarding inappropriate illness behavior represent substandard practice in view of the importance of these conclusions for the assessment of impairment or disability.

COMBINATORIAL POLYNOMIALLY COMPUTABLE CHARACTERISTICS OF SUBSTITUTIONS AND THEIR PROPERTIES

2020 ◽  
Vol 7 (2) ◽  
pp. 34-41
Author(s):  
VLADIMIR NIKONOV ◽  
◽  
ANTON ZOBOV ◽  
Keyword(s):  
Mathematical Expectation ◽  
Point Of View ◽  
Small Range ◽  
Computational Point ◽  
Wide Range ◽  
Bijective Function ◽  
The Difference ◽  
Element Base ◽  
Selection Of

The construction and selection of a suitable bijective function, that is, substitution, is now becoming an important applied task, particularly for building block encryption systems. Many articles have suggested using different approaches to determining the quality of substitution, but most of them are highly computationally complex. The solution of this problem will significantly expand the range of methods for constructing and analyzing scheme in information protection systems. The purpose of research is to find easily measurable characteristics of substitutions, allowing to evaluate their quality, and also measures of the proximity of a particular substitutions to a random one, or its distance from it. For this purpose, several characteristics were proposed in this work: difference and polynomial, and their mathematical expectation was found, as well as variance for the difference characteristic. This allows us to make a conclusion about its quality by comparing the result of calculating the characteristic for a particular substitution with the calculated mathematical expectation. From a computational point of view, the thesises of the article are of exceptional interest due to the simplicity of the algorithm for quantifying the quality of bijective function substitutions. By its nature, the operation of calculating the difference characteristic carries out a simple summation of integer terms in a fixed and small range. Such an operation, both in the modern and in the prospective element base, is embedded in the logic of a wide range of functional elements, especially when implementing computational actions in the optical range, or on other carriers related to the field of nanotechnology.

THE INFLUENCE OF TILLAGE SYSTEMS ON THE GROWTH, DEVELOPMENT AND YIELD OF LONG-FLAX

2020 ◽  
Author(s):  
V. Dumych ◽  
Keyword(s):  
Growth And Development ◽  
Field Experiments ◽  
Conservation Tillage ◽  
Mineral Fertilizers ◽  
Tillage Systems ◽  
Yield And Quality ◽  
Tillage System ◽  
The Difference ◽  
Flax Seeds

The purpose of research: to improve the technology of growing flax in the Western region of Ukraine on the basis of the introduction of systems for minimizing tillage, which will increase the yield of trusts and seeds. Research methods: field, laboratory, visual and comparative calculation method. Research results: Field experiments included the study of three tillage systems (traditional, canning and mulching) and determining their impact on growth and development and yields of trusts and flax seeds. The traditional tillage system included the following operations: plowing with a reversible plow to a depth of 27 cm, cultivation with simultaneous harrowing and pre-sowing tillage. The conservation system is based on deep shelfless loosening of the soil and provided for chiseling to a depth of 40 cm, disking to a depth of 15 cm, cultivation with simultaneous harrowing, pre-sowing tillage. During the implementation of the mulching system, disking to a depth of 15 cm, cultivation with simultaneous harrowing and pre-sowing tillage with a combined unit was carried out. Tillage implements and machines were used to perform tillage operations: disc harrow BDVP-3,6, reversible plow PON-5/4, chisel PCh-3, cultivator KPSP-4, pre-sowing tillage unit LK-4. The SZ-3,6 ASTPA grain seeder was used for sowing long flax of the Kamenyar variety. Simultaneously with the sowing of flax seeds, local application of mineral fertilizers (nitroammophoska 2 c/ha) was carried out. The application of conservation tillage allows to obtain the yield of flax trust at the level of 3,5 t/ha, which is 0,4 t/ha (12.9 %) more than from the area of traditional tillage and 0,7 t/ha (25 %) in comparison with mulching. In the area with canning treatment, the seed yield was the highest and amounted to 0,64 t/ha. The difference between this option and traditional and mulching tillage reaches 0,06 t/ha (10,3 %) and 0.10 t/ha (18.5 %), respectively. Conclusions. Preservation tillage, which is based on shelf-free tillage to a depth of 40 cm and disking to a depth of 15 cm has a positive effect on plant growth and development, yield and quality of flax.

Влияние экологического состояния водоисточника на режим работы водопроводных очистных сооружений

2020 ◽  
Author(s):  
P. Bykova ◽  
I. Egorova ◽  
A. Strelkov ◽  
L. Talovyria ◽  
O. Nesterenko ◽  
...  
Keyword(s):  
Water Quality ◽  
Water Reservoir ◽  
Water Source ◽  
Optimal Dose ◽  
Source Water ◽  
Regulatory Requirements ◽  
Water Quality Control ◽  
Water Abstraction ◽  
The City

При изучении качества воды источника водоснабжения г. Самары Саратовского водохранилища особое внимание было уделено основным показателям, влияющим на выбор реагентной обработки: мутность, перманганатная окисляемость и цветность. Сезонные изменения качества воды водохранилища требуют постоянной корректировки дозы реагентов с целью достижения нормативных требований к качеству очищенной воды. Приводятся результаты производственных исследований изменения качества воды Саратовского водохранилища в створе водозаборов г. Самары за 20172019 годы по мутности, перманганатной окисляемости и цветности. В связи с аномальными температурными перепадами и наступлением осеннего паводка (конец декабря 2019 г. и январь 2020 г.) резко изменилось качество воды водохранилища по цветности и перманганатной окисляемости. Отмечено, что увеличение указанных показателей потребовало повышения дозы реагентов при очистке исходной воды. Оптимальная доза реагентов постоянно коректируется в зависимости от состава исходной воды на флокуляторе Lovibond ЕТ-750 . Регулярное проведение пробного коагулирования позволило поддерживать качество очищенной воды в соответствии с нормативными требованиями СанПиН 2.1.4.1074-01 Питьевая вода. Контроль качества , кроме цветности и железа общего, так как превышение этих показателей наблюдалось в пределах погрешности методов измерения.While studying the water quality of the water source of the city of Samara the Saratov water reservoir, special attention was paid to the main indicators that influence the choice of chemical treatment: turbidity, permanganate index and color. Seasonal changes in the water quality of the water reservoir require constant adjustment of the chemical dose in order to meet the regulatory requirements to the quality of treated water. The results of the studies of changes in the water quality of the Saratov reservoir at the water abstraction points of the city of Samara for 20172019 by turbidity, permanganate index and color are presented. Due to the abnormal temperature differences and onset of autumn flood (end of December 2019 and January 2020), the water quality in the water reservoir dramatically changed in color and permanganate index. It was noted that an increase in these indicators required an increase in the dose of chemicals during the source water purification. The optimal dose of chemicals is selected with Lovibond ET-750 flocculator depending on the composition of the source water. Regular test coagulation allowed maintaining the quality of purified water in accordance with the regulatory requirements of SanPiN 2.1.4.1074-01 Drinking water. Quality control , except for color and total iron since the values of these indicators were increased within the measurement accuracy.

Pengaruh ovaprim, aromatase inhibitor, dan hipofisa terhadap kualitas telur ikan Lele Dumbo (Clarias gariepinus)

2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Erwin A. Aziz ◽  
Ockstan Kalesaran
Keyword(s):  
Survival Rate ◽  
Experimental Design ◽  
Aromatase Inhibitor ◽  
Fish Larvae ◽  
Clarias Gariepinus ◽  
Randomized Design ◽  
Completely Randomized Design ◽  
The Difference ◽  
Hatching Eggs

This study aimed to determine the effect of ovaprim hormone, aromatase inhibitor and pituitary on the quality of the catfish eggs (Clarias gariepinus). Experimental Design used was Completely Randomized Design (CRD) with four treatments, each with three replications. Treatment A: ovaprim; treatment B: Aromatase inhibitors, treatment C: hypophysis and treatment D: Control. The results showed that the difference in treatment gave highly significant effect on fertilization and hatching eggs but no significant effect on the survival rate of larvae. Aromatase inhibitor hormone was the best because it provided highly significant effect on fertilization (92.66%), hatchability of eggs (95%), and surviva rate (81.33%) of fish larvae.   Keywords : Clarias gariepinus. Ovaprim, Aromatase Inhibitor, Hypophysis, egg, larvae

Chronic Ischemic Monomelic Neuropathy after Arteriovenous Fistula Creation: A Unique Presentation of Vascular Steal

2020 ◽  
Vol 3 (2) ◽  
pp. 147-150
Author(s):  
Kaczynski RE ◽  
Asaad Y ◽  
Valentin-Capeles N ◽  
Battista J
Keyword(s):  
Arteriovenous Fistula ◽  
Complete Loss ◽  
Dialysis Access ◽  
Loss Of Function ◽  
Access Site ◽  
Surgical Ligation ◽  
Arteriovenous Access ◽  
Vascular Steal ◽  
Steal Syndrome

We discuss a case of a 58 year old male who presented for left upper extremity steal syndrome including ischemic monomelic neuropathy (IMN) 1.5 months after arteriovenous fistula creation. He presented after three surgical attempts to salvage his fistula with rest pain, complete loss of function with contracture of the 4th and 5th digits, and loss of sensation in the ulnar distribution for more than three weeks. At our institution, he underwent surgical ligation of the distal fistula and creation of a new fistula proximally, resulting in complete resolution of his vascular steal symptoms almost immediately despite the chronicity prior to surgical presentation. Our patient provides a unique perspective regarding dialysis access salvage versus patient quality of life. The patients’ functional status and pain levels should take precedence over salvage of an arteriovenous access site, and early ligation of the access should be completed prior to chronic IMN development. However, if a patient presents late along the IMN course, we recommend strong consideration of access ligation in order to attempt to regain the full neurovascular function of the extremity as we experienced in our patient.

Multivariate micropollutants analysis in marine waters

1995 ◽  
Vol 32 (9-10) ◽  
pp. 341-348
Author(s):  
V. Librando ◽  
G. Magazzù ◽  
A. Puglisi
Keyword(s):  
Multivariate Data Analysis ◽  
Partial Least Squares Regression ◽  
Environmental Chemistry ◽  
Sampling Site ◽  
Principal Component ◽  
Least Squares Regression ◽  
Organic Micropollutants ◽  
Suspended Material ◽  
The Difference

The monitoring of water quality today provides a great quantity of data consisting of the values of the parameters measured as a function of time. In the marine environment, and especially in the suspended material, increasing importance is being given to the presence of organic micropollutants, particularly since some are known to be carcinogenic. As the number of measured parameters increases examining the data and their consequent interpretation becomes more difficult. To overcome such difficulties, numerous chemometric techniques have been introduced in environmental chemistry, such as Multivariate Data Analysis (MVDA), Principal Component Analysis (PCA) and Partial Least Squares Regression (PLSR). The use of the first technique in this work has been applied to the interpretation of the quality of Augusta bay, by measuring the concentration of numerous organic micropollutants, together with the classical water pollution parameters, in different sites and at different times. The MVDA has highlighted the difference between various sampling sites whose data were initially thought to be similar. Furthermore, it has allowed a choice of more significant parameters for future monitoring and more suitable sampling site locations.

Non-steady variations of SOD and phosphate release rate due to changes in the quality of the overlying water

2000 ◽  
Vol 42 (3-4) ◽  
pp. 265-272 ◽  
Author(s):  
T. Inoue ◽  
Y. Nakamura ◽  
Y. Adachi
Keyword(s):  
Release Rate ◽  
Oxygen Demand ◽  
Phosphate Concentration ◽  
Sediment Oxygen Demand ◽  
Biochemical Reactions ◽  
Overlying Water ◽  
Phosphate Release ◽  
Do Concentration ◽  
The Difference

A dynamic model, which predicts non-steady variations in the sediment oxygen demand (SOD) and phosphate release rate, has been designed. This theoretical model consists of three diffusion equations with biochemical reactions for dissolved oxygen (DO), phosphate and ferrous iron. According to this model, step changes in the DO concentration and flow velocity produce drastic changes in the SOD and phosphate release rate within 10 minutes. The vigorous response of the SOD and phosphate release rate is caused by the difference in the time scale of diffusion in the water boundary layer and that of the biochemical reactions in the sediment. Secondly, a negative phosphate transfer from water to sediment can even occur under aerobic conditions. This is caused by the decrease in phosphate concentration in the aerobic layer due to adsorption.

Regulatory requirements and comparison in approval of new and generic drugs in United States of America and Japan:-Implication for Future strategies

2020 ◽  
Vol 07 ◽  
Author(s):  
Paramjeet Malik ◽  
Neelam Pawar ◽  
Kavita Bahmani
Keyword(s):  
Generic Drugs ◽  
Drug Product ◽  
Drug Approval ◽  
Approval Process ◽  
Regulatory Requirements ◽  
Team Members ◽  
Regulatory Authorities ◽  
Effective Manner ◽  
Review Team

: Safety, efficacy and quality of a therapeutic product is the major concern for the pharmaceutical companies. FDA and PMDA are the main regulatory authorities in USA & JAPAN respectively that ensures the maintenance of these required parameters by forming standard guidelines and process for drug approval. These regulatory authorities’ reviews each step of a pharmaceutical drug product from its discovery phase to marketed product. Dossier plays an important role during the approval process of a drug product, as it allows both applicant and review team members to evaluate the data in an effective manner. A dossier consists of five modules containing informative data of various stages of a drug product but in a brief pattern with folders and subfolders. In the present paper, the authors focus on in-depth review of approval process for new and generic drugs in USA and Japan.

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