scholarly journals Polymeric coating lubricates nanocontainers to escape macrophage uptake for bioreceptor recognition

2022 ◽  
Author(s):  
Yulong Sun ◽  
Yanxin Han ◽  
Yannong Dou ◽  
Xinqi Gong ◽  
Haimang Wang ◽  
...  
Keyword(s):  
Polymeric Coating ◽  
Macrophage Uptake

Mathematical and algorithmic support of a model of drying a band with polymeric coating.

2018 ◽  
Vol 6 (87) ◽  
pp. 19-27 ◽  
Author(s):  
V. M. Oskolkov ◽  
T. O. Petrova ◽  
I. A. Varfolomeyev ◽  
L. N. Vinogradova ◽  
E. V. Ershov
Keyword(s):  
Polymeric Coating ◽  
Algorithmic Support

Novel Electro Polymerization Method to Synthesized Anti-corrosion Coated Layer on Stainless Steel Surface from (N-Benzothiazolyl Maleamic Acid) and Study its Biological Activity

2018 ◽  
Vol 9 (3) ◽  
Author(s):  
Muna I Khalaf ◽  
Khulood A Saleh ◽  
Khalil S Khalil
Keyword(s):  
Stainless Steel ◽  
Chemical Structure ◽  
Inhibition Efficiency ◽  
Steel Plate ◽  
Polymeric Coating ◽  
Stainless Steel Surface ◽  
Plate Electrode ◽  
Before And After ◽  
Maleamic Acid ◽  
Polymerization Method

Electro polymerization of N-benzothiazolyl maleamic acid (NBM) was carried out on stainless steel plate electrode in a protic medium of monomer aqueous solution using electrochemical oxidation procedure in electrochemical cell.Spectroscopic characterization techniques were investigated to obtain information about the chemical structure of polymer. The anti-corrosion action of polymer was investigated on stainless steel by electrochemical polarization method. In addition, the effect of adding nanomaterial (TiO2, ZnO (bulk-nano)) to monomer solution on the corrosion behavior of stainless steel was investigated. The results obtained showed that the corrosion rate of S-steel increased with temperature increase from 293K to 323K and the values of inhibition efficiency by coating polymer increase with nanomaterial addition. Apparent energies of activation have been calculated for the corrosion process of S-steel in acidic medium before and after polymeric coating. Furthermore were studied the effect of the preparing polymer on some strain of bacteria.

Clickable Cellulosic Surfaces for Peptide-Based Bioassays

2019 ◽  
Author(s):  
Maria Teresa Odinolfi ◽  
Alessandro Romanato ◽  
Greta Bergamaschi ◽  
Alessandro Strada ◽  
Laura Sola ◽  
...  
Keyword(s):  
Target Recognition ◽  
Real Case ◽  
Polymeric Coating ◽  
Healthy Controls ◽  
Nonspecific Adsorption ◽  
Cellulosic Materials ◽  
Cellulose Substrates

The use of peptides in paper-based analytics is a highly appealing field, yet it suffers from severe limitations. This is mostly due to the loss of effective target recognition properties of this relatively small bioprobes upon nonspecific adsorption onto cellulose substrates. Here, we address this issue by introducing a simple polymer-based strategy to obtain clickable cellulosic surfaces, that we exploited for the chemoselective bioconjugation of peptide bioprobes. Our method largely outperformed standard adsorption-based immobilization strategy in a challenging, real-case immunoassay, namely the diagnostic discrimination of Zika+ individuals from healthy controls. Of note, the clickable polymeric coating not only allows efficient peptides bioconjugation, but it provides favorable anti-fouling properties to the cellulosic support. We envisage our strategy to broaden the repertoire of cellulosic materials manipulation and promote a renewed interest in peptide-based paper bioassays.

Clickable Cellulosic Surfaces for Peptide-Based Bioassays

2019 ◽  
Author(s):  
Maria Teresa Odinolfi ◽  
Alessandro Romanato ◽  
Greta Bergamaschi ◽  
Alessandro Strada ◽  
Laura Sola ◽  
...  
Keyword(s):  
Target Recognition ◽  
Real Case ◽  
Polymeric Coating ◽  
Healthy Controls ◽  
Nonspecific Adsorption ◽  
Cellulosic Materials ◽  
Cellulose Substrates

The use of peptides in paper-based analytics is a highly appealing field, yet it suffers from severe limitations. This is mostly due to the loss of effective target recognition properties of this relatively small bioprobes upon nonspecific adsorption onto cellulose substrates. Here, we address this issue by introducing a simple polymer-based strategy to obtain clickable cellulosic surfaces, that we exploited for the chemoselective bioconjugation of peptide bioprobes. Our method largely outperformed standard adsorption-based immobilization strategy in a challenging, real-case immunoassay, namely the diagnostic discrimination of Zika+ individuals from healthy controls. Of note, the clickable polymeric coating not only allows efficient peptides bioconjugation, but it provides favorable anti-fouling properties to the cellulosic support. We envisage our strategy to broaden the repertoire of cellulosic materials manipulation and promote a renewed interest in peptide-based paper bioassays.

Fabrication Technologies and Applications of Graphene-based co-polymeric Nano-composites: its challenges and Future works

2019 ◽  
Vol 09 ◽  
Author(s):  
Pratik Chhapia ◽  
Harshad Patel
Keyword(s):  
Review Paper ◽  
Polymeric Coating ◽  
Nano Composites ◽  
Future Prospects ◽  
Electrical And Optical Properties ◽  
In Situ Techniques ◽  
Surface Areas ◽  
Ink Jet ◽  
Enhanced Conductivity

: Graphene based co-polymeric Nano-composites explored and trending in various applications as ascribing to its enhanced conductivity and controlled modification with wide specific surface areas. With the number of advantages of co-polymeric coating on Graphene or Graphene sheets and their derivatives, Graphene based co-polymeric Nano-composites fabricated by various techniques (deposition, ink jet, electro spinning, spin coating, in-situ techniques, etc.) and different conducting co-polymers show its exceptional chemical, mechanical, electrical and optical properties. Therefore, in the today’s world with greater quantities of various properties of co-polymer with Graphene based Nano-composites with enhanced stability, selectivity and sensitivity have been formed. In this review paper, we have particularly focused on recent advancing in fabrication of different technologies with the help of Graphene based co-polymeric Nano-composites and its various trending and future applications. Finally, on the personal standpoint; the key challenges of Graphene based co-polymeric Nano-composites are mentioned in hope to shed a light on their potential future prospects.

scholarly journals Delivery of Cinnamic Aldehyde Antioxidant Response Activating nanoParticles (ARAPas) for Vascular Applications

Antioxidants ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 709
Author(s):  
Ana E. Cartaya ◽  
Halle Lutz ◽  
Sophie Maiocchi ◽  
Morgan Nalesnik ◽  
Edward M. Bahnson
Keyword(s):  
Ex Vivo ◽  
Antioxidant Response ◽  
Related Factor ◽  
Cinnamic Aldehyde ◽  
Vsmc Proliferation ◽  
Nrf2 Activation ◽  
Selective Delivery ◽  
And Migration ◽  
Inner Vessel ◽  
Macrophage Uptake

Selective delivery of nuclear factor erythroid 2-related factor 2 (Nrf2) activators to the injured vasculature at the time of vascular surgical intervention has the potential to attenuate oxidative stress and decrease vascular smooth muscle cell (VSMC) hyperproliferation and migration towards the inner vessel wall. To this end, we developed a nanoformulation of cinnamic aldehyde (CA), termed Antioxidant Response Activating nanoParticles (ARAPas), that can be readily loaded into macrophages ex vivo. The CA-ARAPas-macrophage system was used to study the effects of CA on VSMC in culture. CA was encapsulated into a pluronic micelle that was readily loaded into both murine and human macrophages. CA-ARAPas inhibits VSMC proliferation and migration, and activates Nrf2. Macrophage-mediated transfer of CA-ARAPas to VSMC is evident after 12 h, and Nrf2 activation is apparent after 24 h. This is the first report, to the best of our knowledge, of CA encapsulation in pluronic micelles for macrophage-mediated delivery studies. The results of this study highlight the feasibility of CA encapsulation and subsequent macrophage uptake for delivery of cargo into other pertinent cells, such as VSMC.

scholarly journals Enhanced macrophage uptake of synthetically glycosylated human placental beta-glucocerebrosidase.

1982 ◽  
Vol 257 (5) ◽  
pp. 2193-2199
Author(s):  
T W Doebber ◽  
M S Wu ◽  
R L Bugianesi ◽  
M M Ponpipom ◽  
F S Furbish ◽  
...  
Keyword(s):  
Macrophage Uptake

scholarly journals NIR-responsive MXene nanobelts for wound healing

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Lin Jin ◽  
Xiaoqing Guo ◽  
Di Gao ◽  
Cui Wu ◽  
Bin Hu ◽  
...  
Keyword(s):  
Wound Healing ◽  
Vitamin E ◽  
Surface Area ◽  
Near Infrared ◽  
Coating Layer ◽  
High Surface ◽  
High Surface Area ◽  
High Mass ◽  
Polymeric Coating ◽  
Mass Loading

AbstractEffectively achieving wound healing is a great challenge. Herein, we facilely prepared temperature-responsive MXene nanobelt fibers (T-RMFs) carrying vitamin E with a controllable release ability for wound healing. These T-RMFs were composed of MXene nanosheets spread along polyacrylonitrile and polyvinylpyrrolidone composite nanobelts together with a thermosensitive PAAV- coating layer. The high mass loading and high surface area of the MXene nanosheets endow the T-RMFs with excellent photothermal properties. The temperature could be easily controlled by near-infrared (NIR) irradiation exposure, and then the thermoresponsive polymeric coating layer relaxed the interface to dissolve vitamin E and promote vitamin E release. The T-RMFs demonstrated excellent biocompatibility and wound-healing functions in cellular and animal tests. The facile method, high mass loading, high surface area, excellent wound-healing functions, interesting nanosheet/nanobelt structure, mass production potential, and NIR responsive properties of these T-RMFs indicate the great potential of our nanobelts for wound healing, tissue engineering, and much broader application areas. This facile nanosheet/nanobelt preparation strategy paves a new way for nanomaterial fabrication and applications.

scholarly journals Long-lasting renewable antibacterial porous polymeric coatings enable titanium biomaterials to prevent and treat peri-implant infection

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Shuyi Wu ◽  
Jianmeng Xu ◽  
Leiyan Zou ◽  
Shulu Luo ◽  
Run Yao ◽  
...  
Keyword(s):  
Dental Implant ◽  
Pathogenic Bacteria ◽  
Titanium Surface ◽  
Polymeric Coating ◽  
Antibacterial Efficacy ◽  
Polymeric Coatings ◽  
Implant Infection ◽  
Titanium Surfaces

AbstractPeri-implant infection is one of the biggest threats to the success of dental implant. Existing coatings on titanium surfaces exhibit rapid decrease in antibacterial efficacy, which is difficult to promisingly prevent peri-implant infection. Herein, we report an N-halamine polymeric coating on titanium surface that simultaneously has long-lasting renewable antibacterial efficacy with good stability and biocompatibility. Our coating is powerfully biocidal against both main pathogenic bacteria of peri-implant infection and complex bacteria from peri-implantitis patients. More importantly, its antibacterial efficacy can persist for a long term (e.g., 12~16 weeks) in vitro, in animal model, and even in human oral cavity, which generally covers the whole formation process of osseointegrated interface. Furthermore, after consumption, it can regain its antibacterial ability by facile rechlorination, highlighting a valuable concept of renewable antibacterial coating in dental implant. These findings indicate an appealing application prospect for prevention and treatment of peri-implant infection.

Sign in / Sign up

Export Citation Format

Share Document