scholarly journals Impact of one-rod levonorgestrel implant on the blood chemistry profile

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Eka R. Gunardi ◽  
Raymond Surya ◽  
Inayah Syafitri ◽  
Yogi Pasidri
Keyword(s):  
Lipid Profile ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Blood Chemistry ◽  
Rank Test ◽  
Bivariate Analysis ◽  
Normal Limits ◽  
Signed Rank ◽  
Signed Rank Test ◽  
Aspartate Transferase

AbstractThe aim of this study was to investigate the effect of a one-rod levonorgestrel implant on the blood chemistry profile, including random blood glucose (RBG), haemoglobin (Hb), alanine transferase (ALT), aspartate transferase (AST), and the lipid profile, including total cholesterol, high-density lipoprotein (HDL), low-density lipoprotein (LDL), and triglycerides. This prospective cohort study was conducted at Raden Saleh Clinic, Jakarta, from 2010 to 2012. The implants were inserted subdermally in 30 patients. The subjects were evaluated every 6 month up to 2 years. Bivariate analysis using t-test or Wilcoxon signed rank test was performed for all variables. p < 0.05 was considered a significant value. The Hb, RBG, AST, and lipid profile levels were significantly different before and 6 months after one-rod implant insertion (p < 0.05). However, for 24 months, all of the parameters were still within normal limits and did not differ clinically. One-rod levonorgestrel implant insertion has a minimal effect on all blood chemistry profiles.

Impact of One-Rod Levonorgestrel Implant on Blood Chemistry Profile

2021 ◽  
Author(s):  
Eka R. Gunardi ◽  
Raymond Surya ◽  
Inayah Syafitri ◽  
Yogi Pasidri
Keyword(s):  
Lipid Profile ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Blood Chemistry ◽  
Rank Test ◽  
Bivariate Analysis ◽  
Signed Rank ◽  
Before And After ◽  
Signed Rank Test ◽  
Aspartate Transferase

Abstract Objective: The aim of this study is to investigate the effect of one-rod levonorgestrel implant on the blood chemistry profile which include random blood glucose (RBG), hemoglobin (Hb), alanine transferase (ALT), aspartate transferase (AST), and lipid profile such as total cholesterol, High-density lipoprotein (HDL), Low-density lipoprotein (LDL), and triglycerideMethods: This prospective cohort study was conducted at Raden Saleh Clinic, Jakarta from 2010 to 2012. The implants were inserted subdermally in 30 patients. The subjects were evaluated for 6 months and the blood chemistry profile was followed up to 2 years. Bivariate analysis using t-test or Wilcoxon signed rank test was performed for all variables. The p <0.05 was considered as a significant value. Results: The level of Hb, RBG, AST, and lipid profile was different significantly before and after 6-months one-rod implant insertion (p<0.05). However, in 24 months, all of parameters were still on normal limit and not different clinically. Conclusion: One-rod levonorgestrel implant insertion shows minimal effect to all blood chemistry profiles.

Effect of 6 months intense Yoga practice on lipid profile, thyroxine medication and serum TSH level in women suffering from hypothyroidism: A pilot study

2016 ◽  
Vol 13 (2) ◽  
Author(s):  
Savitri Nilakanthan ◽  
Kashinath Metri ◽  
Nagaratna Raghuram ◽  
Nagendra Hongasandra
Keyword(s):  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Rank Test ◽  
Autonomous Nervous System ◽  
Signed Rank ◽  
Medication Score ◽  
Signed Rank Test ◽  
History Of ◽  
Artery Disease ◽  
Age Range

Abstract: A significant number of women in India are suffering from hypothyroidism. Hypothyroidism is characterized by elevated lipid profiles and thyroid stimulation hormone (TSH). It leads many comorbid conditions such as coronary artery disease, obesity, depression, osteoporosis, sleep apnea, and etc. Yoga is proven to be effective in reducing weight, dyslipidemia, depression and it brings the balance in autonomous nervous system. We aimed to study the effect of 6 months: Twenty-two household women suffering from hypothyroidism between the age range of 30 and 40 (mean±SD; 36.7±3.2) years, with average 4±1.12-year history of hypothyroidism were included in this study. Subjects with known cardiac issues, hypertension, history, recent surgery, slip disc and low back pain were excluded from this study. None of the subjects were on any other medication except thyroxine which was kept during the intervention phage (mean 65.78±22.74 mcg). All the subjects underwent 6 months of: The paired sample t-test showed significant reduction in total cholesterol (p=0.006; –8.99 %), low-density lipoprotein (LDL) (p=0.002; –9.81 %) and triglycerides (p=0.013; –7.6 %), and there was a significant improvement in high-density lipoprotein (HDL) (p=0.02; +9.65 %) along with nonsignificant reduction in TSH level (p=0.452; –9.72 %). Wilcoxon signed-rank test showed significant reduction in thyroxine medication score (p=0.029; –15.30 %) from.: 6 months practice of

scholarly journals Impact of 3 Common ABCA1 Gene Polymorphisms on Optimal vs Non-Optimal Lipid Profile in Greek Young Nurses

2014 ◽  
Vol 8 (1) ◽  
pp. 83-87 ◽  
Author(s):  
Apostolia Marvaki ◽  
Vana Kolovou ◽  
Niki Katsiki ◽  
Maria Boutsikou ◽  
Anastasia Kotanidou ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Gene Polymorphisms ◽  
Educational Institution ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Abca1 Gene ◽  
Normal Limits ◽  
Increased Risk ◽  
The University

Objective: This study is in line with two previous ones from our group. They evaluated the influence of ATP-binding cassette transporter A1 (ABCA1) gene polymorphisms [such as rs2230806 (R219K), rs2230808 (R1587K) and rs4149313 (I883M)] on the human lipid profile (defined as Optimal and Non-Optimal). Methods: The present study included 447 unrelated young women and men self-reported as being healthy and that attended the University of Nursing of Technological and Educational Institution. All subjects were genotyped and the ABCA1 polymorphisms (R219K, R1587K and I883M) were recorded. According to lipid profile [total cholesterol, triglyceride, high-density lipoprotein cholesterol and low-density lipoprotein cholesterol (LDL-C)] the subjects were separated into those with optimal lipid profile (Optimal Group, n=209) and Non-Optimal Group (n=238). Results: No statistical differences were observed in the distribution of R219K, R1587K and I883M polymorphisms according to the lipid profile (p>0.05 in all cases). No statistical differences were observed in the distribution of R219K, R1587K and I883M polymorphisms according to sex (p>0.05 in all cases). However, Logistic Regression revealed that subjects with RK (R1587K polymorphism) genotype had 69% increased risk on average of having LDL-C above normal limits as compared with those with RR genotype. Similarly, subjects with K allele (R1587K polymorphism) had 59% increased risk on average of having LDL-C above normal limits compared with those with R allele. Conclusion: These findings suggest that R1587K polymorphism of ABCA1 gene may influence the lipid profile. However, this needs to be confirmed by larger studies.

scholarly journals Improvement in Metabolic Co-Morbidities after Implantation of CardioMEMS in Patients with Heart Failure with Preserved Ejection Fraction Phenotype

2021 ◽  
Vol 10 (19) ◽  
pp. 4308
Author(s):  
Amit Alam ◽  
Johanna Van Zyl ◽  
Navdeep Nayyar ◽  
Shelley Hall ◽  
Rita Jermyn
Keyword(s):  
Heart Failure ◽  
Metabolic Syndrome ◽  
Ejection Fraction ◽  
Density Lipoprotein ◽  
Rank Test ◽  
Preserved Ejection Fraction ◽  
The Metabolic Syndrome ◽  
Signed Rank ◽  
Signed Rank Test ◽  
Blood Pressures

Background: Heart failure with preserved ejection fraction (HFpEF) patients often have other comorbidities, including obesity, dyslipidemia, hypertension, and diabetes, comprising the metabolic syndrome. The impacts of hemodynamic monitoring via CardioMEMS on these co-morbidities remain unknown. Methods: A retrospective analysis of 29 patients with HFpEF (EF 45% or greater) and CardioMEMS was performed at a single center. Weight, body mass index (BMI), systolic blood pressures (SBP), high-density lipoprotein (HDL), triglycerides (TGL), hemoglobin A1C (HbA1c), and pulmonary artery diastolic pressures (PADP) were assessed at baseline and six months post-implant. Paired t-tests and the Wilcoxon signed-rank test were used, as appropriate, to test differences between time points. Results: These patients were 69% female, with a mean age of 73 years, and 62% had non-ischaemic cardiomyopathies (NICM). At the time of CardioMEMS implantation, average PADP was 20.1 mmHg ± 5.7, weight was 102.6 kg ± 22.7, BMI was 38.0 kg/m2 ± 8.3, SBP was 135 mmHg ± 19, HDL was 42.4 mg/dL ± 11.3, and median TGL was 130 mg/dL (100, 180). At six months we witnessed a decrease by 20.9% in PADP to 15.9 mmHg ± 5.8, (p < 0.001). In addition, the following was noted: weight decreased by 2.5% to 100.0 kg ± 23.2, (p = 0.006), BMI reduced by 2.6% to 37.0 ± 8.2, (p = 0.002), SBP decreased by 6.7% to 126 mmHg ± 16 (p < 0.001), HDL increased by 10.8% to 47 mg/dL ± 11.9 (p < 0.001), and TGL decreased by 15.4% to 110 mg/dL (105, 135) (p = 0.001). 62% of patients were diabetic with no significant improvements in HbA1C values at the 6-month follow-up. Conclusion: The utilization of CardioMEMS to optimize PADP results in an improvement in the comorbidities associated with the metabolic syndrome. Further studies are warranted to validate these findings and delineate clinical significance.

scholarly journals Pengaruh Abdominal Stretching Exercise terhadap Penurunan Dysmenorrhea

2020 ◽  
Vol 7 (1) ◽  
pp. 58
Author(s):  
Yulita Elvira Silviani ◽  
Tita Rosnita ◽  
Buyung Keraman
Keyword(s):  
Sampling Technique ◽  
Rank Test ◽  
Bivariate Analysis ◽  
P Value ◽  
Test Analysis ◽  
Purposive Sampling ◽  
Signed Rank ◽  
Wilcoxon Signed Rank Test ◽  
Post Test ◽  
Signed Rank Test

ABSTRAK           Angka kejadian nyeri menstruasi (dysmenorrhea) di dunia sangat besar, rata-rata lebih dari 50% perempuan disetiap Negara mengalami dysmenorrhea. Menurut data dari WHO, 2010 didapatkan angka kejadian sebesar 1.769.425 jiwa (90%) wanita mengalami dysmenorrhea dengan 10-15% mengalami dysmenorrhea berat. Tujuan penelitian ini adalah untuk mengetahui pengaruh abdominal stretching exercise terhadap penurunan dysmenorrhea pada mahasiswa D III kebidanan STIKes Tri Mandiri Sakti . Metode penelitian yang digunakan adalah analitik kuantitatif metode praeksperimen dengan rancangan desain (one group pre test-post test) dalam satu kelompok dengan analisa uji Wilcoxon Signed Rank Test. Sampel pada penelitian ini sebanyak 19 responden diambil dengan teknik purposive sampling. Analisis penelitian ini menggunakan analisis univariat dan bivariat. Berdasarkan hasil penelitian didapatkan dari 19 responden yang mengalami dysmenorrhea, diperoleh rata-rata skala dysmenorrhea sebelum dilakukan senam 8,00 dan sesudah dilakukan senam diperoleh rata-rata 5,00  Berdasarkan hasil uji analisis terdapat signifikan nilai p-value =0,000 <α=0,05. Ada pengaruh abdominal stretching exercise terhadap penurunan dysmenorrhea pada mahasiswa D III kebidanan STIKES Tri Mandiri Sakti Bengkulu.Kata Kunci: dysmenorrhea; abdominal stretching exercise; remaja putri THE EFFECT OF ABDOMINAL STRETCHING EXERCISE ON DYSMENORRHEA REDUCTIONABSTRACTThe incidence of menstrual pain (dysmenorrheal) in the world is very large, on average more than 50% of women in each country experience dysmenorrheal. According to data from WHO, 2010 there was an incidence of 1,769,425 people (90%) of women having dysmenorrheal with 10-15% having severe dysmenorrheal. The purpose of this study was to determine the effect of abdominal stretching exercise gymnastics on the reduction of dysmenorrheal in students of Diploma of midwifery at STIKES Tri Mandiri Sakti students. The research method used in this quantitative analytical study was pre-experimental method with design design (one group pre-test post test) in one group. With paired simple T-test test analysis and Wilcoxon signed rank test to test the data with normal distribution. The samples in this study were 19 respondents and taken by purposive sampling technique. The analysis of this study used univariate and bivariate analysis with Wilcoxon Signed Rank Test. Based on the results of the study obtained from 19 respondents who experienced dysmenorrheal, obtained on average dysmenorrheal scale before doing 8.00 gymnastics and after doing gymnastics obtained an average of 5.00. Based on the results of the analysis there were significant P-value = 0,000 <α = 0 05 that there is an effect of abdominal stretching exercise on decreasing dysmenorrheal in Diploma midwifery students at level I and II at STIKES Tri MandiriSakti Bengkulu. The conclusion is that there is significant influence of abdominal Stretching to reduce dysmenorrheal pain in Diploma midwifery students of STIKES Tri Mandiri Sakti Bengkulu.Keywords: abdominal stretching exercise; decreasing; female students

scholarly journals PENGARUH PEMBERIAN ENDORPHIN MASSAGE TERHADAP SKALA NYERI IBU BERSALIN DI BPM LU’LUATUL MUBRIKOH, S.ST BANGKALAN

2019 ◽  
Vol 11 (2) ◽  
pp. 1-5
Author(s):  
Nailufar Firdaus
Keyword(s):  
Health Workers ◽  
Statistical Tests ◽  
Univariate Analysis ◽  
Massage Therapy ◽  
Labor Pain ◽  
Rank Test ◽  
Bivariate Analysis ◽  
Constant Pain ◽  
Signed Rank ◽  
Signed Rank Test

Labor is identical to the pain that will be experienced. Physiologically, pain occurs when the muscles of the uterus contract as an effort to open the cervix and push the baby's head towards the pelvis. Based on preliminary studies conducted at the BPM Lu’luatul Mubrikoh, Bangkalan S.ST was obtained from 20 women giving birth, 4 (20%) of the mothers giving birth experienced severe labor pain. The purpose of this study was to analyze the effect of giving endorphin massage on the scale of maternal pain. The design used in this study was to use a pre-experimental design with the One group Pretest posttest approach. The independent variable is endorphin massage while the dependent variable is labor pain. The study population was all 16 maternity mothers with a sample of 15 respondents using non-probability sampling and purposive sampling. Data analysis using univariate analysis normality test and bivariate analysis. The research measuring instrument is the observation sheet analyzed with statistical tests paired t-test or Wilcoxon Signed Rank Test. The results showed that of the 15 respondents given endorphin massage therapy, before being given therapy on average the respondents experienced labor pain with a scale of 6. Whereas after being given endorphin massage therapy the average maternity experience the intensity of labor pain on a pain scale 5. There were 4 people significant reduction in pain, not significant 8, and 3 people with constant pain intensity. The results of the Wicoxon Signed Rank Test statistical test showed ρ value 0.005 which means that α <0.05 Ho was rejected Ha accepted, which means that there are differences in the scale of pain before and after giving endorphin massage to the mother. Health workers should provide the best service to maternity mothers, including one of them trying to overcome or reduce labor pain by various methods.

Melatonin Improves Lipid Profile and Ameliorates Lipid Peroxidation in Patients with Chronic Kidney Disease.

2018 ◽  
pp. 38-45
Keyword(s):  
Lipid Peroxidation ◽  
Placebo Group ◽  
Lipid Profile ◽  
Kidney Diseases ◽  
Oxidized Ldl ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Before And After ◽  
Inhibit Lipid Peroxidation ◽  
Controlled Clinical Study

Dyslipidemia and oxidative modifications of lipid are frequently associated in patients with chronic kidney diseases (CKD) and considered the most important risk factors for cardiovascular events. Melatonin is a well-known potent antioxidant and has beneficial effect on lipid metabolism. the study was designed to evaluate if Melatonin could improve lipid profile and ameliorates lipid peroxidation. This single blind placebo controlled clinical study carried out on 41 patients with CKD who were randomized into two groups, control groups (n=20) those who received placebo cap and melatonin group those who received 5mg melatonin (n=21). Lipid profile [total cholesterol (TC), triglyceride (TG), high-density lipoprotein (HDL-C), low-density lipoprotein (LDL-C)] and parameters of lipid peroxidation [oxidized LDL (oxLDL) and malondialdehyde (MDA) were measured before and after 12 weeks of the treatment. After 12 weeks of treatment, melatonin significantly increased HDL-C and decreased LDL-C compared to the initial value. The elevation in HDL-C and reduction in LDL-C were significantly different from that in placebo group. Also, both oxLDL and MDA levels significantly lowered by melatonin compared to the baseline and to the placebo group. Collectively, the results of our study showed that melatonin has advantageous effect on lipid profile and inhibit lipid peroxidation in patients with CKD.

Effect of Turmeric and Ginger on Lipid Profile in Male Rats Exposed to Oxidative Stress

2019 ◽  
Vol 10 (01) ◽  
Author(s):  
Eman A. Al-Rekabi ◽  
Dheyaa K. Alomer ◽  
Rana Talib Al-Muswie ◽  
Khalid G. Al-Fartosi
Keyword(s):  
Oxidative Stress ◽  
Hydrogen Peroxide ◽  
Drinking Water ◽  
Lipid Profile ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Male Rats ◽  
Control Group ◽  
Very Low Density Lipoprotein ◽  
Low Density

The present study aimed to investigate the effect of turmeric and ginger on lipid profile of male rats exposed to oxidative stress induced by hydrogen peroxide H2O2 at a concentration of 1% given with consumed drinking water to male rats. Methods: 200 mg/kg from turmeric and ginger were used, and the animals were treatment for 30 days. Results: the results showed a significant increase in cholesterol, triglycerides, low density lipoprotein (LDL), very low density lipoprotein (VLDL), whereas it explained a significant decrease in high density lipoprotein (HDL) of male rats exposed to oxidative stress when compared with control group. the results showed a significant decrease in cholesterol, triglycerides, (LDL), (VLDL), whereas it explained a significant increase in (HDL) of rats treated with turmeric and ginger at dose 200 mg/kg when compared with male rats exposed to oxidative stress.

PENGARUH TIRAH BARING TERHADAP PENURUNAN RASA MUAL PADA KLIEN GASTRITIS DI PELAYANAN KESEHATAN

2019 ◽  
Vol 3 (1) ◽  
pp. 25
Author(s):  
Dewi Nurhanifah ◽  
Desy Noor Latifah Sari ◽  
Rahmawati Rahmawati
Keyword(s):  
Rank Test ◽  
Purposive Sampling ◽  
Signed Rank ◽  
Wilcoxon Signed Rank Test ◽  
Signed Rank Test

Salah satu masalah kesehatan yang sering dialami adalah penyakit gastritis. Gejala yang sering dikeluhkan oleh penderita gastritis adalah mual. Salah satu penatalaksanaan keperawatan yang dapat mengurangi rasa mual adalah tirah baring. Penelitian ini bertujuan untuk mengetahui pengaruh tirah baring terhadap penurunan rasa mual pada klien gastritis di Pelayanan Kesehatan. Metode penelitian menggunakan eksperimental dengan bentuk penelitian one group pretest-posttest design. Populasi dan sampel adalah klien yang mengalami mual di Wilayah Kerja Puskesmas  yang berjumlah 15 orang. Sampel diambil dengan teknik purposive sampling. Alat pengumpul data menggunakan observasi. Analisa data melalui uji Wilcoxon Signed Rank Test. Hasil penelitian menujukkan klien gastritis sebelum tirah baring mengalami mual ringan sebanyak 7 orang (46,7%), sesudah tirah baring mengalami tidak mual sebanyak 7 orang (46,7%). Ada pengaruh tirah baring terhadap penurunan rasa mual pada klien gastritis di Pelayanan Kesehatan (ρ value = 0,001).

Efektifitas Kompres Jahe Merah Hangat Dan Kompres Serai Terhadap Penurunan Intensitas Nyeri Arthritis Remathoid Pada Lanjut Usia Di Desa Mojoranu Kecamatan Dander Kabupaten Bojonegoro

2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Ferawato Ferawati
Keyword(s):  
Pain Intensity ◽  
Therapy Group ◽  
The Elderly ◽  
Rank Test ◽  
Test Design ◽  
Signed Rank ◽  
Wilcoxon Signed Rank Test ◽  
Post Test ◽  
Signed Rank Test ◽  
Red Ginger

ABSTRAKReumatoid Artritis (RA) merupakan penyakit muscoloskelektal yang sering terjadi pada usia lanjut. Gangguan pada system muscoloskelektal yang ditandai dengan munculnya nyeri sendi dan kekakuan yang mengakibatkan penurunan kemampuan fisiologis atau kualitas hidup lansia. Dampak dari Reumatoid Artritis dapat menimbulkan beberapa keluhan dan dapat menyebabkan kelumpuhan. Untuk menganalisis efektifitas kompres jahe merah hangat dan kompres serai hangat terhadap penurunan intensitas nyeri artitris remauthoid pada lanjut usia.Metode Penelitian: Jenis penelitian adalah quasy experimental dengan two group pre – post test design. Subjek adalah sebagian lansia yang penderita Arthritis Remathoid di Desa Sumberagung Kecamatan Dander Kabupaten Bojonegoro. Subjek dibagi menjadi dua kelompok yaitu kelompok I (n=15) diberi perlakuan kompres jahe hangat dan II (n=15) diberi perlakuan kompres serai hangat. Analisis yang digunakan uji Mann Whitney U Test dan Wilcoxon Signed Ranks Test dengan ingkat kemaknaan α = 0,05.Hasil uji Wilcoxon Signed Rank Test, didapat keduanya mempunyai nilai kemaknaan yaitu ρ value = 0,000. Nilai ρ = 0,031 pada kelompok kompres serai hangat dan kelompok kompres jahe merah ρ value = 0,165. Hasil uji Mann Withney U Test pada Post perlakuan kedua terapi diperoleh selisih nilai nyeri pada kompres jahe ρ= 0,003 dan selisih nilai nyeri kompres serai ρ value = 0,001.Penggunaan kompres jahe merah lebih efektif dibandingkan dengan kompres serai terhadap penurunan intensitas nyeri arthritis remathoid. Kata Kunci: usia lanjut, Reumatoid Artritis (RA), jahe merah, serai, perbedaan efektifitas.    ABSTRACTReumatoid Artritis (RA) is a musculoskeletal which frequently occurs in the elderly. The disorders in the musculoskeletal system are noted by the occurrence of pain in the joints and stiffness which reduces the physiological abilities or life quality of the elderly. The disease causes many such complaints and  consequences of the disease rheumatoid arthritis may experience paralysis. The aims of this study is to analyze the effect of warm red ginger compress therapy and warm lemongrass compress therapy against of  Decreased pain intensity in  the elderly  with  artitris remauthoid. The study was Queasy experimental with two group pre – post test design. Subjects were some elderly people with Arthritis Remathoid in Sumberagung Village, Dander Sub District, Bojonegoro District. Subjects were divided into two groups: group I (n-15) with warm ginger compress therapy, and II (n=15) with warm lemongrass compress therapy. The analyses used in this study were the Mann Whitney U Test and Wilcoxon Signed Ranks Test with α of 0.05. Results of Wilcoxon Signed Rank Test obtained Both have meaning p value of  0.000. ρ value = 0,031 in a warm lemongrass compress therapy group and obtained of warm ginger compress therapy group ρ value = 0,165. The results of Mann Withney U Test on Post treatment second therapy, obtained difference of warm ginger compress therapy with ρ value= 0,003 and difference of warm lemongrass compress therapy with ρ value = 0,001.The use of warm ginger compresses therapy are more effective than a warm lemongrass compress therapy against decreased pain intensity in  the elderly  with  artitris remauthoid.  Keywords: elderly, artitris remauthoid, red ginger, lemongrass, differences in effectiveness

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