scholarly journals Geographic pattern of human mobility and COVID-19 before and after Hubei lockdown

Annals of GIS ◽  
2020 ◽  
pp. 1-12
Author(s):  
T. Edwin Chow ◽  
Yusik Choi ◽  
Mei Yang ◽  
David Mills ◽  
Ricci Yue
Author(s):  
Bing Song ◽  
Xiao-Yong Yan ◽  
Suoyi Tan ◽  
Bin Sai ◽  
Shengjie Lai ◽  
...  

Understanding the spatial interactions of human mobility is crucial for urban planning, traffic engineering, as well as for the prevention and control of infectious diseases. Although many models have been developed to model human mobility, it is not clear whether such models could also capture the traveling mechanisms across different time periods (e.g. workdays, weekends or holidays). With one-year long nationwide location-based service (LBS) data in China, we investigate the spatiotemporal characteristics of population movements during different time periods, and make thorough comparisons for the applicability of five state-of-the-art human mobility models. We find that population flows show significant periodicity and strong inequality across temporal and spatial distribution. A strong “backflow” effect is found for cross-city movements before and after holidays. Parameter fitting of gravity models reveals that travels in different type of days consider the attractiveness of destinations and cost of distance differently. Surprisingly, the comparison indicates that the parameter-free opportunity priority selection (OPS) model outperforms other models and is the best to characterize human mobility in China across all six different types of days. However, there is still an urgent need for development of more dedicated models for human mobility on weekends and different types of holidays.


2020 ◽  
Author(s):  
Nicola Borri ◽  
Francesco Drago ◽  
Chiara Santantonio ◽  
Francesco Sobbrio

In response to the Covid-19 outbreak, among other previous ``non-pharmaceutical interventions'', on March 22, 2020 the Italian Government imposed an economic lockdown and ordered the closing of all non-essential economic activities. This paper estimates the causal effect of this measure on mortality by Covid-19 and on mobility patterns. The identification of the causal effect exploits the variation in the number of active workers across municipalities induced by the economic lockdown. The difference-in-difference empirical design compares outcomes in municipalities above and below the median variation in the share of active population before and after the lockdown within a province, also controlling for municipality-specific dynamics, daily-shocks at the provincial level and municipal unobserved characteristics. Our results show that the intensity of the economic lockdown is associated to a statistically significant reduction in mortality by Covid-19 and, in particular, for age groups between 40-64 and older. Back of the envelope calculations indicate that 4,793 deaths were avoided, in the 26 days between April 5 to April 30, in the 3,518 municipalities which experienced a more intense lockdown. Assuming linearity, a 1 percentage point reduction in the share of active population caused a 1.32 percentage points reduction in mortality by Covid-19. We also find that the economic lockdown, as expected, led to a reduction in human mobility. Several robustness checks corroborate our empirical findings.


2020 ◽  
Author(s):  
Matteo Serafino ◽  
Higor S. Monteiro ◽  
Shaojun Luo ◽  
Saulo D. S. Reis ◽  
Carles Igual ◽  
...  

The spread of COVID-19 caused by the recently discovered SARS-CoV-2 virus has become a worldwide problem with devastating consequences. To slow down the spread of the pandemic, mass quarantines have been implemented globally, provoking further social and economic disruptions. Here, we address this problem by implementing a large-scale contact tracing network analysis to find the optimal quarantine protocol to dismantle the chain of transmission of coronavirus with minimal disruptions to society. We track billions of anonymized GPS human mobility datapoints from a compilation of hundreds of mobile apps deployed in Latin America to monitor the evolution of the contact network of disease transmission before and after the confinements. As a consequence of the lockdowns, people's mobility across the region decreases by ~53%, which results in a drastic disintegration of the transmission network by ~90%. However, this disintegration did not halt the spreading of the disease. Our analysis indicates that superspreading k-core structures persist in the transmission network to prolong the pandemic. Once the k-cores are identified, the optimal strategy to break the chain of transmission is to quarantine a minimal number of 'weak links' with high betweenness centrality connecting the large k-cores. Our results demonstrate the effectiveness of an optimal tracing strategy to halt the pandemic. As countries race to build and deploy contact tracing apps, our results could turn into a valuable resource to help deploy protocols with minimized disruptions.


2020 ◽  
Vol 12 (18) ◽  
pp. 3042
Author(s):  
Kainan Zhang ◽  
Gerrit de Leeuw ◽  
Zhiqiang Yang ◽  
Xingfeng Chen ◽  
Jiashuang Jiao

The Corona Virus Disease 2019 (COVID-19) appeared in Wuhan, China, at the end of 2019, spreading from there across China and within weeks across the whole world. In order to control the rapid spread of the virus, the Chinese government implemented a national lockdown policy. It restricted human mobility and non-essential economic activities, which, as a side effect, resulted in the reduction of the emission of pollutants and thus the improvement of the air quality in many cities in China. In this paper, we report on a study on the changes in air quality in the Guanzhong Basin during the COVID-19 lockdown period. We compared the concentrations of PM2.5, PM10, SO2, NO2, CO and O3 obtained from ground-based monitoring stations before and after the COVID-19 outbreak. The analysis confirmed that the air quality in the Guanzhong Basin was significantly improved after the COVID-19 outbreak. During the emergency response period with the strictest restrictions (Level-1), the concentrations of PM2.5, PM10, SO2, NO2 and CO were lower by 37%, 30%, 29%, 52% and 33%, respectively, compared with those before the COVID-19 outbreak. In contrast, O3 concentrations increased substantially. The changes in the pollutant concentrations varied between cities during the period of the COVID-19 pandemic. The highest O3 concentration changes were observed in Xi’an, Weinan and Xianyang city; the SO2 concentration decreased substantially in Tongchuan city; the air quality had improved the most in Baoji City. Next, to complement the sparsely distributed air quality ground-based monitoring stations, the geographic and temporally weighted regression (GTWR) model, combined with satellite observations of the aerosol optical depth (AOD) and meteorological factors was used to estimate the spatial and temporal distributions of PM2.5 and PM10 concentrations with a resolution of 6 km × 6 km before and after the COVID-19 outbreak. The model was validated by a comparison with ground-based observations from the air quality monitoring network in five cities in the Guanzhong Basin with excellent statistical metrics. For PM2.5 and PM10 the correlation coefficients R2 were 0.86 and 0.80, the root mean squared errors (RMSE) were 11.03 µg/m3 and 14.87 µg/m3 and the biases were 0.19 µg/m3 and −0.27 µg/m3, which led to the conclusion that the GTWR model could be used to estimate the PM concentrations in locations where monitoring data were not available. Overall, the PM concentrations in the Guanzhong Basin decreased substantially during the lockdown period, with a strong initial decrease and a slower one thereafter, although the spatial distributions remained similar.


Author(s):  
Martin S Andersen ◽  
Ana I Bento ◽  
Anirban Basu ◽  
Chris Marsicano ◽  
Kosali Simon

Most U.S. colleges have reopened campuses for in-person teaching this Fall, following rapid closures at the onset of the COVID-19 pandemic this Spring. Despite administrative efforts at mitigation and preventive measures, the large congregation of students within close quarters has caused public health concerns. In this paper, we examine college reopenings' association with changes in human mobility within campuses and in COVID-19 incidence in the counties of the campuses, over a two-week period before and after college reopenings. To estimate the daily reproduction number (Rt), we used a Bayesian framework. Using a difference-in-differences design comparing areas with a college campus, before and after reopening, to areas without a campus, we find that after college reopenings for face-to-face instruction, COVID-19 incidence in the county increased on average by a statistically significant 0.024 per thousand residents, following increases in mobility on campus. Similarly, we estimated increased transmission locally after reopening, with a rising trend in Rt. The increase in cases was larger in counties with colleges that drew students from areas with increasing incidence rates.


Author(s):  
J. Temple Black

Tool materials used in ultramicrotomy are glass, developed by Latta and Hartmann (1) and diamond, introduced by Fernandez-Moran (2). While diamonds produce more good sections per knife edge than glass, they are expensive; require careful mounting and handling; and are time consuming to clean before and after usage, purchase from vendors (3-6 months waiting time), and regrind. Glass offers an easily accessible, inexpensive material ($0.04 per knife) with very high compressive strength (3) that can be employed in microtomy of metals (4) as well as biological materials. When the orthogonal machining process is being studied, glass offers additional advantages. Sections of metal or plastic can be dried down on the rake face, coated with Au-Pd, and examined directly in the SEM with no additional handling (5). Figure 1 shows aluminum chips microtomed with a 75° glass knife at a cutting speed of 1 mm/sec with a depth of cut of 1000 Å lying on the rake face of the knife.


Author(s):  
R. F. Bils ◽  
W. F. Diller ◽  
F. Huth

Phosgene still plays an important role as a toxic substance in the chemical industry. Thiess (1968) recently reported observations on numerous cases of phosgene poisoning. A serious difficulty in the clinical handling of phosgene poisoning cases is a relatively long latent period, up to 12 hours, with no obvious signs of severity. At about 12 hours heavy lung edema appears suddenly, however changes can be seen in routine X-rays taken after only a few hours' exposure (Diller et al., 1969). This study was undertaken to correlate these early changes seen by the roengenologist with morphological alterations in the lungs seen in the'light and electron microscopes.Forty-two adult male and female Beagle dogs were selected for these exposure experiments. Treated animals were exposed to 94.5-107-5 ppm phosgene for 10 min. in a 15 m3 chamber. Roentgenograms were made of the thorax of each animal before and after exposure, up to 24 hrs.


Author(s):  
M. H. Wheeler ◽  
W. J. Tolmsoff ◽  
A. A. Bell

(+)-Scytalone [3,4-dihydro-3,6,8-trihydroxy-l-(2Hj-naphthalenone] and 1,8-di- hydroxynaphthalene (DHN) have been proposed as intermediates of melanin synthesis in the fungi Verticillium dahliae (1, 2, 3, 4) and Thielaviopsis basicola (4, 5). Scytalone is enzymatically dehydrated by V. dahliae to 1,3,8-trihydroxynaphthalene which is then reduced to (-)-vermelone [(-)-3,4- dihydro-3,8-dihydroxy-1(2H)-naphthalenone]. Vermelone is subsequently dehydrated to DHN which is enzymatically polymerized to melanin.Melanin formation in Curvularia sp., Alternaria sp., and Drechslera soro- kiniana was examined by light and electron-transmission microscopy. Wild-type isolates of each fungus were compared with albino mutants before and after treatment with 1 mM scytalone or 0.1 mM DHN in 50 mM potassium phosphate buffer, pH 7.0. Both chemicals were converted to dark pigments in the walls of hyphae and conidia of the albino mutants. The darkened cells were similar in appearance to corresponding cells of the wild types under the light microscope.


Author(s):  
T. Gulik-Krzywicki ◽  
M.J. Costello

Freeze-etching electron microscopy is currently one of the best methods for studying molecular organization of biological materials. Its application, however, is still limited by our imprecise knowledge about the perturbations of the original organization which may occur during quenching and fracturing of the samples and during the replication of fractured surfaces. Although it is well known that the preservation of the molecular organization of biological materials is critically dependent on the rate of freezing of the samples, little information is presently available concerning the nature and the extent of freezing-rate dependent perturbations of the original organizations. In order to obtain this information, we have developed a method based on the comparison of x-ray diffraction patterns of samples before and after freezing, prior to fracturing and replication.Our experimental set-up is shown in Fig. 1. The sample to be quenched is placed on its holder which is then mounted on a small metal holder (O) fixed on a glass capillary (p), whose position is controlled by a micromanipulator.


Author(s):  
R. M. Anderson

Aluminum-copper-silicon thin films have been considered as an interconnection metallurgy for integrated circuit applications. Various schemes have been proposed to incorporate small percent-ages of silicon into films that typically contain two to five percent copper. We undertook a study of the total effect of silicon on the aluminum copper film as revealed by transmission electron microscopy, scanning electron microscopy, x-ray diffraction and ion microprobe techniques as a function of the various deposition methods.X-ray investigations noted a change in solid solution concentration as a function of Si content before and after heat-treatment. The amount of solid solution in the Al increased with heat-treatment for films with ≥2% silicon and decreased for films <2% silicon.


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