scholarly journals THE RACES THAT CONSTITUTE THE GROUP OF COMMON FIBROBLASTS

1933 ◽  
Vol 58 (4) ◽  
pp. 401-414 ◽  
Author(s):  
Raymond C. Parker
Keyword(s):  
Chick Embryo ◽  
Gradual Increase ◽  
Physiological State ◽  
Gradual Decrease ◽  
Functional Differences ◽  
Different Ages ◽  
The Moment ◽  
The Individual

1. Races of fibroblasts that are functionally distinct have been isolated from the various tissues and organs of a single chick embryo. 2. Functionally distinct races of fibroblasts have also been isolated from corresponding parts of embryos of different ages. 3. Under the conditions of the experiments, and for the particular races of fibroblasts that have been studied, it has not been possible to demonstrate a gradual decrease, or a gradual increase, in the rate of multiplication of fibroblasts obtained from corresponding parts of embryos of gradually increasing ages. 4. Experiments made on strains of fibroblasts derived from the mesonephros and metanephros of a 16 day chick embryo have indicated that the rate of multiplication of these cells in a given medium reflects the physiological state, at the moment of isolation, of the particular part of the embryo from which they are obtained. 5. The rate of multiplication of a given race of fibroblasts in a particular medium does not serve, necessarily, as an index of the age of the individual from which the race is derived. 6. The functional differences that distinguish the various races of fibroblasts are permanent; they are retained by the cells from passage to passage indefinitely, despite such attempts as have thus far been made to change them.

Erfahrung ohne Erfahrenden

2009 ◽  
Vol 2009 (1) ◽  
pp. 61-78
Author(s):  
Petr Kouba
Keyword(s):  
Phenomenological Approach ◽  
Work Of Art ◽  
New Beginning ◽  
Individual Structure ◽  
The World ◽  
Il Y A ◽  
Individual Existence ◽  
The Moment ◽  
The Individual ◽  
Intentional Structure

This article examines the limits of Heidegger’s ontological description of emotionality from the period of Sein und Zeit and Die Grundbegriffe der Metaphysik along the lines outlined by Lévinas in his early work De l’existence à l’existant. On the basis of the Lévinassian concept of “il y a”, we attempt to map the sphere of the impersonal existence situated out of the structured context of the world. However the worldless facticity without individuality marks the limits of the phenomenological approach to human existence and its emotionality, it also opens a new view on the beginning and ending of the individual existence. The whole structure of the individual existence in its contingency and finitude appears here in a new light, which applies also to the temporal conditions of existence. Yet, this is not to say that Heidegger should be simply replaced by Lévinas. As shows an examination of the work of art, to which brings us our reading of Moravia’s literary exposition of boredom (the phenomenon closely examined in Die Grundbegriffe der Metaphysik), the view on the work of art that is entirely based on the anonymous and worldless facticity of il y a must be extended and complemented by the moment in which a new world and a new individual structure of experience are being born. To comprehend the dynamism of the work of art in its fullness, it is necessary to see it not only as an ending of the world and the correlative intentional structure of the individual existence, but also as their new beginning.

Monkey on My Back. An Autoethnographic Narrative of a Therapeutic Experience

2020 ◽  
Author(s):  
Adam Wiesner
Keyword(s):  
Personal Experience ◽  
Meaning Making ◽  
The Self ◽  
Symbolic Language ◽  
Discursive Practices ◽  
Therapeutic Experience ◽  
Postmodern Philosophy ◽  
The Moment ◽  
The Individual ◽  
Global Uncertainty

With a conscious attempt to contribute to contemporary discussions in mad/trans/queer/monster studies, the monograph approaches complex postmodern theories and contextualizes them from an autoethnographic methodological perspective. As the self-explanatory subtitle reads, the book introduces several topics as revelatory fields for the author’s self-exploration at the moment of an intense epistemological and ontological crisis. Reflexively written, it does not solely focus on a personal experience, as it also aims at bridging the gap between the individual and the collective in times of global uncertainty. There are no solid outcomes defined; nevertheless, the narrative points to a certain—more fluid—way out. Through introducing alternative ways of hermeneutics and meaning-making, the book offers a synthesis of postmodern philosophy and therapy, evolutionary astrology as a symbolic language, embodied inquiry, and Buddhist thought that together represent a critical attempt to challenge the pathologizing discursive practices of modern disciplines during the neoliberal capitalist era.

scholarly journals Effects of detergent on the sulphation of chondroitin by cell-free preparations from chick-embryo epiphyseal cartilage

1992 ◽  
Vol 285 (2) ◽  
pp. 577-583 ◽  
Author(s):  
G Sugumaran ◽  
J E Silbert
Keyword(s):  
Chick Embryo ◽  
Supernatant Fraction ◽  
Random Pattern ◽  
Type I ◽  
Type Ii ◽  
Enzyme Preparations ◽  
Enzyme Substrate ◽  
Ionic Detergent ◽  
The Individual ◽  
Triton X

The effects of the non-ionic detergent Triton X-100 on 6-sulphation of two species of endogenous nascent proteochondroitin by a chick-embryo cartilage microsomal system was examined. Sulphation of the larger (Type I) species with adenosine 3′-phosphate 5′-phosphosulphate was slightly diminished when Triton X-100 was present, whereas sulphation of the smaller (Type II) species was slightly enhanced. An ordered rather than random pattern of sulphation was obtained for the smaller proteoglycan, but with a considerably lower degree of sulphation than that of the larger proteochondroitin. These differences were consistent with other differences between these two species as described previously. Sulphation of exogenous [14C]chondroitin and exogenous proteo[3H]chondroitin by the microsomal system with Triton X-100 present produced ordered rather than random sulphation patterns. When a 100,000 g supernatant fraction was utilized for sulphation of [14C]chondroitin or proteo[3H]chondroitin, Triton X-100 was not needed, and ordered sulphation was still obtained. When hexasaccharide was used, sulphation of multiple N-acetylgalactosamine residues of the individual hexasaccharides resulted. This was relatively independent of Triton X-100 or the concentration of the hexasaccharide acceptors. With soluble enzyme, sulphation of multiple N-acetylgalactosamine residues on the individual hexasaccharide molecules was even greater, so that tri-sulphated products were found. This suggests that ordered rather than random sulphation of chondroitin with these enzyme preparations is due to enzyme-substrate interaction rather than to membrane organization.

scholarly journals Morphological, molecular and functional differences of adult bone marrow- and adipose-derived stem cells isolated from rats of different ages

2012 ◽  
Vol 318 (16) ◽  
pp. 2034-2048 ◽  
Author(s):  
Cristina Mantovani ◽  
Stefania Raimondo ◽  
Maryam S. Haneef ◽  
Stefano Geuna ◽  
Giorgio Terenghi ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Adipose Derived Stem Cells ◽  
Adult Bone Marrow ◽  
Functional Differences ◽  
Different Ages ◽  
Adult Bone

scholarly journals Comparison of oxygen uptake during and after the execution of resistance exercises and exercises performed on ergometers, matched for intensity

2016 ◽  
Vol 53 (1) ◽  
pp. 179-187 ◽  
Author(s):  
José Vilaça-Alves ◽  
Nuno Miguel Freitas ◽  
Francisco José Saavedra ◽  
Christopher B. Scott ◽  
Victor Machado dos Reis ◽  
...  
Keyword(s):  
Oxygen Uptake ◽  
Ventilatory Threshold ◽  
Lactate Concentration ◽  
Blood Lactate Concentration ◽  
Lower Limbs ◽  
Lower Body ◽  
Load Intensity ◽  
Moment Effect ◽  
The Moment ◽  
The Individual

AbstractThe aim of this study was to compare the values of oxygen uptake (VO2) during and after strength training exercises (STe) and ergometer exercises (Ee), matched for intensity and exercise time. Eight men (24 ± 2.33 years) performed upper and lower body cycling Ee at the individual’s ventilatory threshold (VE/VCO2). The STe session included half squats and the bench press which were performed with a load at the individual blood lactate concentration of 4 mmol/l. Both sessions lasted 30 minutes, alternating 50 seconds of effort with a 10 second transition time between upper and lower body work. The averaged overall VO2 between sessions was significantly higher for Ee (24.96 ± 3.6 ml·kg·min-1) compared to STe (21.66 ± 1.77 ml·kg·min-1) (p = 0.035), but this difference was only seen for the first 20 minutes of exercise. Absolute VO2 values between sessions did not reveal differences. There were more statistically greater values in Ee compared to STe, regarding VO2 of lower limbs (25.44 ± 3.84 ml·kg·min-1 versus 21.83 ± 2·24 ml·kg·min-1; p = 0.038) and upper limbs (24.49 ± 3.84 ml·kg·min-1 versus 21.54 ± 1.77 ml·kg·min-1; p = 0.047). There were further significant differences regarding the moment effect (p<0.0001) of both STe and Ee sessions. With respect to the moment × session effect, only VO2 5 minutes into recovery showed significant differences (p = 0.017). In conclusion, although significant increases in VO2 were seen following Ee compared to STe, it appears that the load/intensity, and not the material/equipment used for the execution of an exercise, are variables that best influence oxygen uptake.

scholarly journals INFLUENCE OF POPULATION IMMUNITY PECULIARITIES ON THE STRUCTURE OF MEASLES AND RUBELLA PREVALENCE

2018 ◽  
Vol 8 (3) ◽  
pp. 341-348 ◽  
Author(s):  
A. P. Toptygina ◽  
M. A. Smerdova ◽  
M. A. Naumova ◽  
N. P. Vladimirova ◽  
T. A. Mamaeva
Keyword(s):  
Protective Immunity ◽  
Measles Virus ◽  
Gradual Increase ◽  
Significant Negative Correlation ◽  
Population Immunity ◽  
Healthy Donors ◽  
Different Ages ◽  
Protective Antibodies ◽  
Prophylactic Vaccines ◽  
Measles Incidence

According to the lasting serological investigations of patients with rubella and measles, a major factor that determines the resistance to the infections is specific antibodies, that are still circulating in blood of recovered persons during their life. Since vaccinated people are also included in this concept, serological monitoring of people different ages who get vaccinated against rubella and measles is conducted in Russia. However the discrepancy between specific immunity intensity and the measles incidence was showed last years. Using “Vector Best” kits, the study of the anti-measles and antirubella population immunity in scale of age: under 1 year, 1–2 years, 3–6 years, 7–14 years, 15–17 years, 18–30 years, 31–40 years, 41–50 years, and 51–60 years was carried out in Moscow and Moscow region in 2013 (period of unfavorable epidemic situation). The serum probes were obtained from 654 random healthy donors and 646 patients with serologically confirmed measles infection. As a result, gradual increase of percentage of people with protective antibodies to rubella and measles have been demonstrated: 81.3% donors aged 7–14 years were protected from measles and more than 90% — from rubella. Moreover, percentage of individuals who have had immunity to rubella were the same in adults too. The most marked increase of percentage of seronegative persons to measles virus (40% and more) was in age from 18 to 30 years, and in groups over the age 40 years old protection reaches 85–95%. Comparison between percentage of measles patients different ages and percentage of persons with protective antibodies in serum have demonstrated significant negative correlation between measles prevalence and the level of specific antibody in population (r = –0.76). According to the results, increase (to 28%) and decrease (to 2.9%) of measles patients aged 18 to 30 and 51 to 60 years are based on decrease (to 55%) and increase (to 95%) of persons with protective immunity, respectively. Results of analysis of measles prevalence in different ages have demonstrated, that among adult measles patients (18–50 years) 14.5% responded on infection by secondary immune response; among children and teenagers there were no such patients, that proves the significant effectiveness of prophylactic vaccines.

scholarly journals The Influence of Heavy Metal Ions on the Viability and Metabolic Enzyme Activity of the Marbled Crayfish Procambarus virginalis (Lyko, 2017)

2018 ◽  
Vol 70 ◽  
pp. 11-23 ◽  
Author(s):  
Oleg Marenkov ◽  
Mykola V. Prychepa ◽  
Julia Kovalchuk
Keyword(s):  
Heavy Metals ◽  
Heavy Metal ◽  
Enzyme Activity ◽  
Metal Ions ◽  
Heavy Metal Ions ◽  
Physiological State ◽  
Metabolic Enzyme ◽  
Nickel Ions ◽  
The Individual ◽  
Marbled Crayfish

In the experiment with marbled crayfishProcambarusvirginalis(Lyko, 2017), chronic effects of various concentrations of heavy metal ions on the physiological state and enzyme activity were investigated. The obtained results showed that among the investigated heavy metals nickel ions influenced the weight indexes and mortality of crustaceans the most negatively. According to the results of the research, significant changes were noted in the individual biochemical parameters of marbled crayfish under the influence of manganese, lead and nickel ions. The most significant changes in the activity of lactate dehydrogenase were detected in muscle tissues affected by manganese and nickel ions. A significant decrease in the activity of succinate dehydrogenase in muscle of marbled crayfish was determined after the action of heavy metal ions. Investigation of changes in the activity of alkaline phosphatase under the influence of the ions of manganese, lead and nickel has its own characteristics, which indicates certain violations in the tissues of cell membranes. Changes in the activity of enzymes were also reflected in the overall protein content. Changes in these parameters may indicate a rapid biochemical response of crustaceans to the toxic effects of heavy metals.

scholarly journals Doppler Shift of Radio Signals Transmitted between Orbiting Satellites

1982 ◽  
Vol 35 (2) ◽  
pp. 155 ◽  
Author(s):  
PL Dyson ◽  
JA Bennett
Keyword(s):  
Electron Concentration ◽  
Doppler Shift ◽  
Rate Of Change ◽  
Line Of Sight ◽  
Concentration Gradients ◽  
Mean Velocity ◽  
Radio Signals ◽  
The Mean ◽  
The Moment ◽  
The Individual

A general expression, applicable at VHF and above, is derived for the Doppler shift of radio signals transmitted between two satellites embedded in the ionosphere. The Doppler shift is made up of several contributions which depend on (a) the rate of change of the free space path between the satellites, (b) the components, perpendicular to the line of sight between the satellites, of both the mean velocity of the satellites and the electron concentration gradients, (c) the moment of the perpendicular electron concentration gradients and the deviations from the mean of the individual satellite perpendicular velocities, (d) the velocity components along the line of sight between the satellites, and the electron concentration values at each satellite, and (e) changes occurring in the ionosphere with time.

scholarly journals The development of conscious self-regulation of workers of coal industry enterprises as a condition for ensuring the safety of professional activities

2021 ◽  
Author(s):  
Irina Stanislavovna Morozova ◽  
Evgeniia Aleksandrovna Medovikova ◽  
Daria Nikolaevna Grinenko ◽  
Anastasiia Evgenevna Kargina
Keyword(s):  
Time Perspective ◽  
Self Regulation ◽  
Coal Industry ◽  
Professional Activity ◽  
Actual Problem ◽  
Professional Activities ◽  
Broad Concept ◽  
The Subject ◽  
The Moment ◽  
The Individual

The actual problem of our time at the enterprises of the Kuzbass coal industry is the moment of ensuring the psychological security of the employee's personality. Psychological security is a fairly broad concept that includes many components and is exposed to various factors [2]. The aim of the study is to consider the importance of self-regulation of the individual as a condition for ensuring the safety of the subject of professional activity. The following methods and techniques were used in the study: The method "Style of self-regulation of behavior" by V. I. Morosanova; Test "Meaning-life orientations" by D. A. Leontiev; Questionnaire by H. Zachera and M. Freze "Professional time perspective of the future". The research is based on the development and testing of the technology of psychological and pedagogical influence in the form of reflexive seminars, which allows to increase the level of awareness of self-regulation of subjects of professional activity.

scholarly journals APRENDIZAJE PARA LA GENERACIÓN DE CONOCIMIENTO

2020 ◽  
Vol 13 (3) ◽  
pp. 279
Author(s):  
Laura Elizabeth Cervantes Benavides
Keyword(s):  
Student Learning ◽  
Learning Process ◽  
Metacognitive Abilities ◽  
The Moment ◽  
The Individual ◽  
Teaching Learning ◽  
The Relationship ◽  
The Way

Facing the problems for understanding student learning and the way that makes the relationship and integration of learned knowledge easier, this work is presented, which objective is to identify in the teaching-learning process, at the moment in which the individual relates and integrates the knowledge it acquires. In this document, the assumption was made is, In greater depth of reflection, the student strengthens his cognitive and metacognitive abilities.

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