scholarly journals Gastric cancer incidence and predictions: Observational Study (Monastir, Tunisia: 2002-2030)

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
R Bannour ◽  
I Zemni ◽  
C Ben Nasrallah ◽  
N Aroua ◽  
H Abroug ◽  
...  

Abstract Introduction Gastric cancer is a major health burden worldwide. Based on GLOBOCAN 2018 data, stomach cancer is the fifth most common neoplasm and the third most deadly cancer, with an estimated 783,000 deaths in 2018. Unfortunately, only a few countries have set up extensive programs of early screening. In Tunisia the gastric cancer ranks among the ten most frequent cancers with more than 637 new cases per year. The aim of this study was to we report trends in the gastric cancer incidence during the span of time between 2002 and 2013 from the population-based cancer registry of the centre of Tunisia, and to predict the future number of cancer cases by 2030. Methods The cancer incidence data were collected from the cancer register of the Tunisian Center from 2003 to 2012.The data were stratified by cancer site, sex and age. We used SPSS software in order to calculate the crude incidence rates and standardized incidence rates. SPSS software was used in order to estimate the future number of cancer cases by 2030. Results During our study period, 326 cases of gastric cancer were observed. 53.1% of our patients were male with a sex ratio male to female 1.13.The crude incidence rates were 5.71 for male patients and 5.43 for females. The standardized incidence rates were 7.22 and 6.3 respectively for male and female patients. A stable trend was observed. Only 28 cases of gastric cancer are predicted by 2030. Conclusions Over the recent, there has been a slight decrease in gastric cancer rates. Many preventive steps should be encouraged in order to maintain this decreasing trend such as changing dietary habits by encouraging the consumption of fresh fruit and vegetables, as well as decreasing the use of tobacco and salt. Key messages Gastric cancer is a major health burden worldwide, only a few countries have set up extensive programs of early screening. Changingdietary habits by encouraging the consumption of fresh fruit and vegetables, as well as decreasing the use of tobacco and salt.

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
R Bannour ◽  
I Zemni ◽  
C Ben Nasrallah ◽  
N Aroua ◽  
M Kacem ◽  
...  

Abstract Introduction Cancer is an eminent public health issue in the developing countries. The risk factors incriminated in cancer higher incidence are multiple such as the growing population rates, increasing tobacco consumption, the changes of diet and lifestyle. In Tunisia, there are three population-based cancer registries at the present time providing data on cancer incidence and survival. According to the data published by WHO International Agency for Research on Cancer (IACR) (GLOBOCAN 2018), prostate cancer in Tunisia ranks fifth among cancers with almost 819 new cases per year. The aim of this study was to we report trends in the cancer incidence during the span of time between 2002 and 2013 from the population-based cancer registry of the centre of Tunisia, and to predict the future number of cancer cases by 2030. Methods The cancer incidence data were collected from the Center cancer registries from 2003 to 2012.The data were stratified by cancer site, sex and age. We used SPSS software in order to calculate the crude incidence rates and age-standardized incidence rates. SPSS software was used in order to estimate the future number of cancer cases by 2030. Results A total of 725 cases of prostate cancer were enregistrated. The mean age of patients was 71.6 ±10.61years. The crude incidence rates were estimated 23.537. The standardized incidence rate was 33.92. A significant positive trend was noted with a b = 0133 and p < 10-3. 1033 new cases are predicted by 2030 Conclusions The data of the cancer register of the center shows that the incidence of cancer is rising, and it is consistent with the National cancer intelligence, but some cancer incidence showed slightly higher, such as thyroid cancer and prostate cancer. In order to face this alarming situation, many preventive steps should be done such as strengthening early screening and diagnosis of cancer, improving clinical research in order to better control the risks factors. Key messages Prediction of the future number of cancer cases is of great interest to society. Prostate cancer in Tunisia ranks fifth among cancers.


Author(s):  
Hamid Salehiniya ◽  
Maryam Mohammadian ◽  
Neda Mahdavifar

ABSTRACTObjective: Gastric cancer is the fifth most common cancer and the third cause of death from cancers in the world and is known as the most deadlycancer in Iran. Since the knowledge about the epidemiological situation and the trend of incidence of this cancer is essential to plan for the preventionand treatment of cancer, this study was performed with the aim of investigating the epidemiological status, the rate and the trend of gastric cancerincidence in Sistan and Baluchestan province.Methods: This study was conducted using existing data and data extracted from the National Cancer Registry System and the Disease ManagementCenter of Iranian Ministry of Health between 2003 and 2008. Age-Standardized incidence rates (ASIR) were calculated using the world standardpopulation. The crude incidence rate was also computed. Cochran–Armitage test for linear trend was used for evaluation of the incidence trend.Results: The number of 255 cases of gastric cancer occurred in the study period that 188 cases were in men and 67 in women. Accordingly, theincidence of gastric cancer has had an ascending trend in Sistan and Baluchestan (p=0.00) and its incidence in men and women has changed to1.18 and 2.73 in 2004 to 1.84 and 4.48 in 2008, respectively. Furthermore, with ageing, the incidence of gastric cancer has increased in both sexes andits incidence was higher in men than women.Conclusion: The incidence of gastric cancer has an increasing trend in Sistan and Baluchestan, hence, etiological surveys and programs of earlydiagnosis are useful in this province to the reduce cancer.Keywords: Incidence, Gastric cancer, Iran, Epidemiology.


2014 ◽  
Vol 15 (3) ◽  
pp. 1111-1117 ◽  
Author(s):  
Nasser Behnampour ◽  
Ebrahim Hajizadeh ◽  
Farid Zayeri ◽  
Shahriar Semnani

Gut ◽  
2020 ◽  
pp. gutjnl-2020-322200 ◽  
Author(s):  
Tsung-Hsien Chiang ◽  
Wei-Jung Chang ◽  
Sam Li-Sheng Chen ◽  
Amy Ming-Fang Yen ◽  
Jean Ching-Yuan Fann ◽  
...  

ObjectiveAlthough mass eradication of Helicobacter pylori has been proposed as a means to eliminate gastric cancer, its long-term effects remain unclear.DesignMass eradication of H. pylori infection was launched in 2004 and continued until 2018 for a high-risk Taiwanese population aged 30 years or older dwelling on Matsu Islands with prevalent H. pylori infection. Test positives for the 13C-urea breath test underwent eradication therapy. We evaluated the effectiveness of the mass eradication in reducing two main outcomes, incidence and mortality rates of gastric cancer, until the end of 2016 and 2018, respectively.ResultsAfter six rounds of mass screening and eradication, the coverage rate reached 85.5% (6512/7616). The referral rate for treatment was 93.5% (4286/4584). The prevalence rates of H. pylori fell from 64.2% to 15.0% with reinfection rates of less than 1% per person-year. The presence and severity of atrophic gastritis and intestinal metaplasia also decreased with time. Compared with the historical control period from 1995 to 2003, the effectiveness in reducing gastric cancer incidence and mortality during the chemoprevention period was 53% (95% CI 30% to 69%, p<0.001) and 25% (95% CI −14% to 51%, p=0.18), respectively. No significant changes were noted in the incidence rates of other digestive tract cancers or the antibiotic resistance rate of H. pylori.ConclusionPopulation-based eradication of H. pylori has significantly reduced gastric cancer incidence with no increase in the likelihood of adverse consequences. A significant reduction in mortality is likely to be achieved with a longer follow-up period.Trial registration numberNCT00155389


2021 ◽  
Vol 50 (Supplement_1) ◽  
Author(s):  
Kishore Chaudhry ◽  
Prashanti Bollu

Abstract Background Age-standardization is common for adjustment of unequal population in different ages as it can influence cancer incidence. However, for planning healthcare services (including screening), one needs absolute magnitude since everyone needs intervention. This study assessed the effect of age-standardization on understanding the global differentials in magnitude of oral cancer. Methods Data on cancer incidence rates of oral cancers for 2008-2012, was obtained from the website of international agency for research on cancer for all 334 population-based cancer registries. Scatter plots were prepared between age-standardized and crude incidence rates to assess the ratio between them according to proportion of old people for all countries. Areas with high occurrence of oral cancer were identified. Results The ratio between age-standardized and crude incidence rate was &gt;1 in countries with high proportion of older population (high-development-index countries), indicating an artificial widening of gap between incidence rates between countries due to age-standardization. Six areas had higher crude incidence rate among men than India. Based on the published estimates, the per-unit-population burden in Europe was 6.3% higher than India, while in USA it was merely 12.5% lower than India. Conclusions The perception of low burden of oral cancer in high-economy countries is artificial, brought about by common practice of age-standardization. Key messages Organization of oral cancer screening activities by countries with resources and expertise will provide much needed knowledge on its natural history and efficacy of control strategies.


Gut ◽  
2020 ◽  
Vol 69 (5) ◽  
pp. 823-829 ◽  
Author(s):  
Melina Arnold ◽  
Jin Young Park ◽  
M Constanza Camargo ◽  
Nuno Lunet ◽  
David Forman ◽  
...  

ObjectivesThe incidence of gastric cancer continues to decrease globally, approaching levels that in some populations could define it as a rare disease. To explore this on a wider scale, we predict its future burden in 34 countries with long-standing population-based data.MethodsData on gastric cancer incidence by year of diagnosis, sex and age were extracted for 92 cancer registries in 34 countries included in Cancer Incidence in Five Continents Plus. Numbers of new cases and age-standardised incidence rates (ASR per 100 000) were predicted up to 2035 by fitting and extrapolating age–period–cohort models.ResultsOverall gastric cancer incidence rates are predicted to continue falling in the future in the majority of countries, including high-incidence countries such as Japan (ASR 36 in 2010 vs ASR 30 in 2035) but also low-incidence countries such as Australia (ASR 5.1 in 2010 vs ASR 4.6 in 2035). A total of 16 countries are predicted to fall below the rare disease threshold (defined as 6 per 100 000 person-years) by 2035, while the number of newly diagnosed cases remains high and is predicted to continue growing. In contrast, incidence increases were seen in younger age groups (below age 50 years) in both low-incidence and high-incidence populations.ConclusionsWhile gastric cancer is predicted to become a rare disease in a growing number of countries, incidence levels remain high in some regions, and increasing risks have been observed in younger generations. The predicted growing number of new cases highlights that gastric cancer remains a major challenge to public health on a global scale.


Author(s):  

The article describes relationship between indicators of the incidence of gastric cancer in the Perm Krai and generalized indicators of pollutants’ discharge to surface water bodies. The work uses data from the annual reports of the Perm Kray on the status of cancer care, environmentl status and protection. A correlation between them with a period of 4 years was revealed. The incidence of gastric cancer in the period from 2010 to 2017 correlate with the amount of pollutant discharges into water bodies from 2006 to 2013. The correlation coefficient was r = 0.75 (high correlation). In the study of the relationships, the duration of the latent period of carcinogenesis was taken into account. Analysis of the values of discharges of pollutants with wastewater into water bodies for the period from 2006 to 2013 showed that the number of discharges increased by 2007, then until 2010 a decrease was observed, and then in 2011–2013 there is a tendency to increase the mass of discharges of pollutants. The time relationship of gastric cancer incidence rates with the number of pollutant discharges into water bodies, with an interval T between them equal to 4 years, is graphically shown. A relationship was found between a disease of gastric cancer and the environmental situation (the value of discharges of pollutants into water bodies), that is, the quality of the environment. The incidence is reduced following a decrease in the amount of pollutants discharged into water bodies in the Perm Kray.


2015 ◽  
Vol 33 (3_suppl) ◽  
pp. 29-29
Author(s):  
Kimberly A Lowe ◽  
Aaron Katz ◽  
Michael A. Kelsh ◽  
Thomas L. Vaughan

29 Background: Gastric and esophageal cancers are the fourth and eighth most common cancers worldwide, with an estimated 1.5 million new cases combined in 2008. A comprehensive, international comparison of the descriptive epidemiology of these diseases is lacking. The objectives of this study are to (1) characterize the current and projected incidence rates and the current case fatality of these cancer types by age and gender within countries in Europe, Asia, the Americas, Oceania, and Africa; (2) describe the temporal variation in cardia and non-cardia gastric cancer and squamous and adenocarcinoma esophageal cancer in the U.S. by age and gender. Methods: Data from GLOBOCAN were used to calculate country-specific incidence rates (per 100,000) for 2012, 2015, and 2025, and the country-specific case fatality (%) in 2012. Data from the National Cancer Institute’s Surveillance, Epidemiology, and End Results (SEER) Program in the U.S. were used to estimate gastric cancer incidence rates from 2004-2011 (per 100,000) and 12-month survival (%) stratified by gender, age (0-64/65+), stage at diagnosis, gastric cancer subtype, and esophageal cancer histology. Joinpoint regression was used to quantify changes in the Average Annual Percent Change (AAPC) in these outcomes. Results: GLOBOCAN results showed wide geographic variation in gastric and esophageal cancer incidence rates. In most countries, the case-fatality among males and females 65+ years was > 60%. In the U.S., the annual incidence of all gastric cancer subtypes decreased significantly among males and females 65+ (AAPC= -2.4% & -1.6%, respectively). Esophageal cancer incidence decreased in both genders and age groups, with a significant decline observed among females 65+ with squamous histology (-3.5%). Twelve-month survival in esophageal cancer showed modest improvements, with a significant increase observed among males 65+ with adenocarcinoma histology (2.0%). Conclusions: The worldwide burden of gastric and esophageal cancers is substantial. In the U.S., declines in incidence and modest improvements in survival of these cancers were observed.


2020 ◽  
Vol 2020 ◽  
pp. 1-11
Author(s):  
Yu-Ching Huang ◽  
Yu-Hung Chen

Introduction. Taiwan has committed itself to cancer prevention. This study investigates the impact of cancer prevention on cancer incidence in Taiwan. Objective. This study describes the secular trends and present status of cancer incidence in Taiwan during the years of 1988 to 2016. Methods. Age-standardized incidence rates (ASRs), age-specific incidence, and sex ratios for all cancers were calculated using data from the Taiwan Cancer Registry System for the years 1988 to 2016. Results and Conclusions. ASRs of cancer for males increased from 150.93 per 105 individuals in 1988 to 330.03 per 105 individuals in 2016, and, for females, they increased from 124.18 per 105 individuals in 1988 to 269.5 per 105 individuals in 2016. We found that cancer incidence has begun at younger ages and that the rates of cancer incidence are increasing faster. This study shows that the incidence of cancer in males has decreased slightly in recent years, while the incidence of cancer in females has continued to increase. The continuous promotion of health literacy, lifestyle modification, HBV and HPV vaccination, and cancer early screening can improve the effectiveness of cancer prevention.


Cancers ◽  
2019 ◽  
Vol 11 (4) ◽  
pp. 534 ◽  
Author(s):  
Amy Colquhoun ◽  
Heather Hannah ◽  
André Corriveau ◽  
Brendan Hanley ◽  
Yan Yuan ◽  
...  

In northern Canada where there is a high prevalence of Helicobacter pylori infection, there is a paucity of information on gastric cancer by the topographical subsites cardia (CGC) and non-cardia (NCGC). Here we describe the incidence of CGC and NCGC, separately, among northern Canadian populations. We used data from the Cancer Incidence in Five Continents Volumes X (CI5X) and XI (CI5XI) to obtain CGC and NCGC incidence for Canada and for Yukon (YT), a northern Canadian territory. Using these data with those provided by the Government of the Northwest Territories (NT), we estimated standardized incidence ratios comparing northern populations to Canada as a whole. We also estimated age-standardized incidence rates to permit comparisons across populations globally. NT and YT populations were disproportionately impacted by gastric cancer, particularly NCGC. This was especially true for Indigenous populations: NCGC incidence rates among NT Indigenous men were 2.7 times the rates among all men in Canada, while rates among NT Indigenous women were 3.1 times the rates among all women in Canada. Similarly, age-standardized rates of NCGC among Indigenous NT residents were comparable to global regions where there is a high burden of NCGC. This study has, for the first time, quantified the incidence of CGC and NCGC for the NT and YT, providing new insights into the burden of these cancers among northern Canadian populations.


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