PSV-13 The Effect of Supplementing Sows with the Leucine Metabolite Beta-hydroxy-beta-methylbutyrate and Vitamin D3 Pre-parturition and During Lactation on Early Piglet Weight

2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 198-198
Author(s):  
John C Fuller ◽  
Fabricio Castro ◽  
Rhuan F Chaves ◽  
Mike Mohr ◽  
John A Rathmacher
Keyword(s):  
Vitamin D3 ◽  
Low Birthweight ◽  
Commercial Production ◽  
Least Square ◽  
Late Gestation ◽  
Lactation Period ◽  
Early Lactation ◽  
And Control ◽  
Leucine Metabolite ◽  
Cross Fostering

Abstract Abstract: Several university studies supplementing calcium beta-hydroxy-beta-methylbutyrate (CaHMB) to sows have reported benefit to piglets such as a reduction in low birthweight piglets, increased piglet birth weight, and increased weaning weights. This study was designed to determine if these benefits would be observed in a commercial production setting using sows whose genetics are known for having a high number of piglets born, which generally results in lower average piglet birth weights. The study was conducted at a commercial farrow to finish operation (Patos de Minas, Minas Gerais, Brazil) and sows studies were randomly assigned to either CaHMB/D (n=41, 3 g CaHMB plus 500 IU Vitamin D3) or a control (n=46, Maltodextrin and CaCO3). Treatments were applied as a top-dress to the morning ration and were applied from 10 days pre-farrowing throughout the lactational period. The results were analyzed using GLM in SAS and Least Square Means±SEM were reported. Piglets from CaHMB/D-supplemented sows had a greater average live birth weights (1.39±0.027 versus 1.32±0.026 kg, respectively, p < 0.05) and 24-hour weights (1.48±0.029 versus 1.39±0.028 kg. respectively, p < 0.02). Normal farm practices were utilized in an attempt to equalize piglet numbers across sows by cross fostering piglets after 24 hours. After analysis of the data at the end of the study, the significant early weight advantage for CaHMB/D-supplemented pigs was eliminated during the cross-fostering process. After equalization, the 24-hour average piglet weights were not significantly different (1.53±0.041 versus 1.45±0.039 kg in CaHMB/D and control, respectively) and, therefore, further advantages to supplementation were not observed. Conclusion: This study would appear to support that feeding CaHMB/D in late gestation and early lactation can improve early piglet weights and further studies with controlled cross-fostering and monitoring individual piglet weight gain are necessary to confirm this advantage is continued throughout the lactation period and into the grower phase.

scholarly journals Effects of Pre-Parturient Iodine Teat Dip Applications on Modulating Aversive Behaviors and Mastitis in Primiparous Cows

Animals ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1623
Author(s):  
Hannah N. Phillips ◽  
Ulrike S. Sorge ◽  
Bradley J. Heins
Keyword(s):  
Staphylococcus Aureus ◽  
Clinical Mastitis ◽  
Lactation Period ◽  
Early Lactation ◽  
Treatment Control ◽  
Intramammary Infections ◽  
Aureus Infection ◽  
Milk Samples ◽  
To Receive ◽  
Teat Dipping

Heifers and their human handlers are at risk for decreased welfare during the early lactation period. This experiment investigated pre-parturient teat dipping and parlor acclimation to reduce mastitis and aversive behaviors in early lactation heifers. Three weeks prior to calving, heifers were randomly assigned to receive either: (1) a weekly 1.0% iodine-based teat dip in the parlor (trained; n = 37) or (2) no treatment (control; n = 30). For the first 3 days of lactation, heifers were milked twice daily, and treatment-blinded handlers assessed behaviors and clinical mastitis. Aseptic quarter milk samples were collected within 36 h of calving and analyzed for pathogens. Control heifers had (OR ± SE) 2.2 ± 0.6 times greater (p < 0.01) odds of kicking during milking. Trained heifers had (OR ± SE) 1.7 ± 0.4 times greater (p = 0.02) odds of being very calm during milking, while control heifers had 2.2 ± 0.8 and 3.8 ± 2.1 times greater (p < 0.04) odds of being restless and very restless or hostile during milking, respectively. Quarters of control heifers had (OR ± SE) 5.4 ± 3.4 greater (p < 0.01) odds of intramammary Staphylococcus aureus infection, yet clinical mastitis was similar among treatments. The results indicate that teat dipping in the parlor weekly for 3 weeks before calving may alleviate some aversive milking behaviors and protect against early lactation S. aureus intramammary infections.

scholarly journals Administration of GnRH at Onset of Estrus, Determined by Automatic Activity Monitoring, to Improve Dairy Cow Fertility during the Summer and Autumn

Animals ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 2194
Author(s):  
Zvi Roth ◽  
Yaron Z. Kressel ◽  
Yaniv Lavon ◽  
Dorit Kalo ◽  
David Wolfenson
Keyword(s):  
Metabolic Diseases ◽  
Experimental Period ◽  
Visual Observation ◽  
Activity Monitoring ◽  
Least Square ◽  
Gnrh Analogue ◽  
Automatic Activity ◽  
Effect Of Treatment ◽  
Uterine Diseases ◽  
And Control

We examined gonadotropin-releasing hormone (GnRH) administration at onset of estrus (OE), determined by automatic activity monitoring (AAM), to improve fertility of dairy cows during the summer and autumn. The study was performed on two dairy farms in Israel. The OE was determined by AAM recorded every 2 h, and a single im dose of GnRH analogue was administered shortly after OE. Pregnancy was determined by transrectal palpation, 40 to 45 d after artificial insemination (AI). Conception risk was analyzed by the GLIMMIX procedure of SAS. Brief visual observation of behavioral estrus indicated that about three-quarters of the events (n = 40) of visually detected OE occurred within 6 h of AAM-detected OE. Accordingly, the GnRH analogue was administered within 5 h of AAM-detected OE, to overlap with the expected endogenous preovulatory LH surge. Overall, pregnancy per AI (P/AI) was monitored over the entire experimental period (summer and autumn) in 233 first, second or third AI (116 and 117 AI for treated and control groups, respectively). Least square means of P/AI for treated (45.8%) and control (39.4%) groups did not differ, but group-by-season interaction tended to differ (p = 0.07), indicating no effect of treatment in the summer and a marked effect of GnRH treatment (n = 58 AI) compared to controls (n = 59 AI) on P/AI in the autumn (56.6% vs. 28.5%, p < 0.03). During the autumn, GnRH-treated mature cows (second or more lactations), and postpartum cows exhibiting metabolic and uterine diseases, tended to have much larger P/AI than their control counterparts (p = 0.07–0.08). No effect of treatment was recorded in the autumn in first parity cows or in uninfected, healthy cows. In conclusion, administration of GnRH within 5 h of AAM-determined OE improved conception risk in cows during the autumn, particularly in those exhibiting uterine or metabolic diseases postpartum and in mature cows. Incorporation of the proposed GnRH treatment shortly after AAM-detected OE into a synchronization program is suggested, to improve fertility of positively responding subpopulations of cows.

scholarly journals Design and Main Results of STURDY: A Randomized Clinical Trial of Four Vitamin D3 Doses to Prevent Falls in Older Adults

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 759-759
Author(s):  
Lawrence Appel ◽  
Jennifer Schrack ◽  
Erin Michos ◽  
Christine Mitchell ◽  
Stephen Juraschek ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D3 ◽  
Primary Outcome ◽  
Vitamin D Supplementation ◽  
Dose Finding ◽  
High Dose ◽  
Hazard Ratios ◽  
Risk Of Falls ◽  
Event Rates ◽  
And Control

Abstract STURDY was a Bayesian, response-adaptive trial with dose-finding and confirmatory stages. Participants (n=688; ≥70years with serum 25(OH)D of 10-29ng/mL) were randomized to 200 (control), 1000, 2000, or 4000 IU/day of vitamin D3. The primary outcome was time to first fall or death over 2 years. During dose-finding, the best non-control dose was determined to be 1000IU/day based on higher primary outcome event rates in the 2000 and 4000IU/day doses than the 1000IU/day dose (posterior probability of being best dose=0.90; hazard ratios[HR] were 1.86 [95%CI: 1.16-2.97] and 1.68 [95%CI: 1.05-2.69], respectively). Participants were then switched from other non-control doses to 1000IU/day, and event rates did not differ between the pooled higher doses and control groups (HR=1.02, P=0.84). There was no heterogeneity by baseline 25(OHD). In conclusion, high-dose vitamin D supplementation ≥1000IU/day did not prevent falls. Whether vitamin D doses &gt;2000IU/day increase the risk of falls is uncertain.

scholarly journals Foaming of rhamnolipids fermentation: impact factors and fermentation strategies

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Zhijin Gong ◽  
Ge Yang ◽  
Chengchuan Che ◽  
Jinfeng Liu ◽  
Meiru Si ◽  
...  
Keyword(s):  
Production Process ◽  
Large Scale ◽  
Commercial Production ◽  
Impact Factors ◽  
Scale Production ◽  
Large Scale Production ◽  
Foaming Behavior ◽  
Production Strategies ◽  
Potential Applications ◽  
And Control

AbstractRhamnolipids have recently attracted considerable attentions because of their excellent biosurfactant performance and potential applications in agriculture, environment, biomedicine, etc., but severe foaming causes the high cost of production, restraining their commercial production and applications. To reduce or eliminate the foaming, numerous explorations have been focused on foaming factors and fermentation strategies, but a systematic summary and discussion are still lacking. Additionally, although these studies have not broken through the bottleneck of foaming, they are conducive to understanding the foaming mechanism and developing more effective rhamnolipids production strategies. Therefore, this review focuses on the effects of fermentation components and control conditions on foaming behavior and fermentation strategies responded to the severe foaming in rhamnolipids fermentation and systematically summarizes 6 impact factors and 9 fermentation strategies. Furthermore, the potentialities of 9 fermentation strategies for large-scale production are discussed and some further strategies are suggested. We hope this review can further facilitate the understanding of foaming factors and fermentation strategies as well as conducive to developing the more effective large-scale production strategies to accelerate the commercial production process of rhamnolipids.

scholarly journals Complete Genome Sequence of an Efficient Vitamin D3-Hydroxylating Bacterium, Pseudonocardia autotrophica NBRC 12743

2018 ◽  
Vol 7 (12) ◽  
Author(s):  
Keitaro Yoshida ◽  
Yoshiaki Yasutake ◽  
Tomohiro Tamura
Keyword(s):  
Vitamin D ◽  
Cytochrome P450 ◽  
Genome Sequence ◽  
Vitamin D3 ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Commercial Production ◽  
Content Type ◽  
Hydroxyvitamin D

Pseudonocardia autotrophica NBRC 12743 contains a cytochrome P450 vitamin D3 hydroxylase, and it is used as a biocatalyst for the commercial production of hydroxyvitamin D3, a valuable compound for medication. Here, we report the complete genome sequence of P. autotrophica NBRC 12743, which could be useful for improving the productivity of hydroxyvitamin D3.

scholarly journals Supplementing Intensively Grazed Late-Gestation and Early-Lactation Dairy Cattle with Chromium

2004 ◽  
Vol 87 (12) ◽  
pp. 4269-4277 ◽  
Author(s):  
M.A. Bryan ◽  
M.T. Socha ◽  
D.J. Tomlinson
Keyword(s):  
Dairy Cattle ◽  
Late Gestation ◽  
Early Lactation

scholarly journals Effect of farrowing pen size on pre-weaning performance of piglets

2021 ◽  
Author(s):  
Katherine D Vande Pol ◽  
Austin L Laudwig ◽  
Aaron M Gaines ◽  
Beau A Peterson ◽  
Caleb M Shull ◽  
...  
Keyword(s):  
Litter Size ◽  
Block Design ◽  
Commercial Production ◽  
Experimental Unit ◽  
Pig Production ◽  
Time Period ◽  
Randomized Complete Block Design ◽  
The Impact ◽  
Cross Fostering ◽  
Size At Birth

Abstract Litter sizes in commercial pig production have increased substantially over recent years; however, farrowing pen sizes have generally not changed over the same time period. The objective of this study was to evaluate the effect of farrowing pen size on piglet pre-weaning growth and mortality. Differences in pen size were created by varying the width of pens of the same length, increasing the creep area available to the piglets. The study used a total of 1,786 litters in a randomized complete block design to compare two Farrowing Pen Size treatments (FPS): Standard (pen width 1.52 m) and Increased (pen width 1.68 m). Litter sizes were equalized across treatments (12.9 ± 1.95 piglets) at 24 h after birth using cross-fostering. Litter weights were collected at birth and weaning (21.3 ± 2.08 d); pre-weaning mortality was recorded. The experimental unit was the litter; models included FPS and replicate. Farrowing Pen Size had no effect (P &gt; 0.05) on litter size at birth (12.8 and 13.0 for the Standard and Increased FPS, respectively), after cross-fostering (12.9 for both treatments), or at weaning (11.2 and 11.3, respectively). There was no effect (P &gt; 0.05) of FPS on total litter or average piglet weight at birth, after cross-fostering, and at weaning. These results suggest no benefit in piglet performance from increasing the width of farrowing pens. As litter sizes continue to increase in commercial production, further research is warranted to re-evaluate the impact of farrowing pen size on pre-weaning mortality.

scholarly journals Spatial Analysis and Geographic Factors Associated with Cutaneous Leishmaniasis in Southern Iran

2020 ◽  
Author(s):  
Mehdi Sharafi ◽  
Zahra Poormotaseri ◽  
Jalal Karimi ◽  
Shahab Rezaeian ◽  
Seyedeh Leila Dehghani ◽  
...  
Keyword(s):  
Spatial Analysis ◽  
Cutaneous Leishmaniasis ◽  
Weather Forecast ◽  
Weather Conditions ◽  
Least Square ◽  
Environmental Data ◽  
Maximum Temperature ◽  
Fars Province ◽  
Disease Pattern ◽  
And Control

Introduction: This study aimed to determine the hotspot areas for Cutaneous Leishmaniasis (CL) in Fasa city and assess the relations between the geographical factors with CL incidence using spatial analysis. Materials and Methods: This ecological study was conducted in Fasa city, data of the CL disease such as the total number of CL cases and the population at risk from 2009 to 2014. Weather conditions' data including the means of temperature, humidity, rainfall, sunny days, rainy days, and evaporation were collected from the weather forecast centers in Fars province. The disease cases' information such as the number of disease cases was collected from all healthcare centers located in Fasa City. Ordinary Least Square (OLS) and Global Moran’s Index (GMI) were used to assess the associations of the various environmental variables with CL incidence and to map clustering of CL cases across the region. Results: The cumulative incidence of CL was 16 per 10,000 populations during a six-year period. The results showed the southern area of Fasa as a hotspot area which is considered as hyperendemic foci for CL. OLS revealed a high incidence of CL in areas with maximum temperature, mean of temperature, mean of evaporation, sunny days and wind velocity. Conclusion: A spatial disease pattern was found in the present study. Hence, substantial consideration to environmental data leads to not only suitable protection against CL but also designing a suitable measure for the prevention and control of the disease.

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