Core Strengthening

2018 ◽  
Author(s):  
Priyesh Mehta ◽  
David J. Cormier ◽  
Julie Ann Aueron ◽  
Jaspal R. Singh
Keyword(s):  
Segmental Motion ◽  
Imaging Data ◽  
Spine Stability ◽  
The Core ◽  
Complex Group ◽  
Strengthening Exercises ◽  
Spine Mechanics ◽  
Vital Component ◽  
And Function

Core strengthening remains a vital component of maintaining spine mechanics and assists in the prevention of injury. A complex group of muscles make up the core and function together to instill spine stability and assist with segmental motion. Understanding the key muscles and how they function is essential to developing a core strengthening program for patients with spinal pathology. This chapter summarizes the anatomy and biomechanics of the core involved in maintaining spine stability. It discusses electromyography and imaging data to help understand how these muscles function during specific exercises. Examples of core strengthening exercises are provided.

scholarly journals The Effectiveness Of Quadriceps Strengthening Exercises Combined With Neuromuscular Electrical Stimulation on Patellofemoral Pain Syndrome

2017 ◽  
Vol 5 (2_suppl2) ◽  
pp. 2325967117S0010
Author(s):  
Sezen Karabörklü Argut ◽  
Nilgün Türker ◽  
Derya Çelik ◽  
Önder İsmet Kılıçoğlu
Keyword(s):  
Electrical Stimulation ◽  
Muscle Strength ◽  
Neuromuscular Electrical Stimulation ◽  
Pain Syndrome ◽  
Quadriceps Strength ◽  
Patellofemoral Pain ◽  
Group I ◽  
Strengthening Exercises ◽  
Group Ii ◽  
And Function

Objective: The weakness of the quadriceps strength in patellofemoral pain syndrome (PFPS) is very evident. Therefore, quadriceps strengthening exercises are very important part of the rehabilitation program. Neuromuscular Electrical Stimulation (NMES) is considered one of the methods for increasing quadriceps muscle strength. To evaluate the effectiveness of combined NMES and strengthening exercises to improve the recovery of quadriceps strength and function in patients with PFPS. Methods: This study was planned as a randomized controlled pilot study. A total of 27 patients (mean age=38.9±10.8 years, range=20-60 years; 16 females) with PFPS were assessed and randomly assigned into 2 groups. Group I received a standard program (quadriceps strengthening, hip strengthening and hamstring stretching) and NMES combined with quadriceps strengthening exercises simultaneously. Group II received the same standard program without NMES. Both groups were enrolled 3 times per week for 40 minutes per day in 6 weeks. Patients were assessed at the baseline, 3 rd, 6th, and 12th weeks of treatment. Quadriceps strength was evaluated by isokinetic dynamometer. The range of motion at testing was set between 0 for extension to 90 for flexion. The test was performed at 60 degrees/sn and concentric maximum peak torque value was recorded. Kujala and Lysholm scores were used for functional assessments. The data were analyzed using the SPSS 20.0. Shapiro-Wilk test was used to assess the distribution of data. The changes in dependent variables before treatment, 3 rd, 6th, and 12th weeks were analyzed using a 2 by 4 mixed-model analysis of variance (ANOVA). Pairwise comparisons with paired t test were used to determine whether the Group I or Group II, has changed over time. An intention- to- treat analysis was performed to impute values for missing data. An alpha level of 0.05 was established. Results: The study was completed with 20 patients. Group I (n=10; mean age=39.4±8.5 years; 7 females) and group II (n=10; mean age=43.2±11.7 years; 5 females) had no differences in pre-operative measures (p>.05). There was significant improvements in within groups statistics of all parameters for both groups (p<.05). No differences in quadriceps strength, Kujala and Lysholm scores between groups were found at the different time points (F= 0.86; p = 0.12, F=0,001; p =0.97, F=0.12; p=0.73, respectively) Conclusion: NMES combined with quadriceps strengthening exercises has no additional effect on PFPS patients’ on muscle strength and function. When considering these results, we believe that there is no need to continue the study in progress. [Table: see text]

The functional vascular anatomy of the swine for research

Vascular ◽  
2021 ◽  
pp. 170853812199650
Author(s):  
Joseph Edwards ◽  
Hossam Abdou ◽  
Neerav Patel ◽  
Marta J Madurska ◽  
Kelly Poe ◽  
...  
Keyword(s):  
Translational Research ◽  
Functional Anatomy ◽  
Three Dimensional ◽  
Vascular Anatomy ◽  
Review Article ◽  
Imaging Data ◽  
Preclinical Research ◽  
Iodinated Contrast ◽  
Translational Research Program ◽  
And Function

Objectives Swine ( Sus Scrofa) are utilized broadly in research settings, given similarities to human vessel size and function; however, there are some important differences for clinicians to understand in order to interpret and perform translational research. This review article uses angiograms acquired in the course of a translational research program to present a description of the functional anatomy of the swine. Methods Digital subtraction angiography and computed tomography angiography were obtained throughout the course of multiple studies utilizing power injection with iodinated contrast. Subtracted two-dimensional images and three-dimensional multiplanar reformations were utilized post image acquisition to create maximal intensity projections and three-dimensional renderings of using open-source software (OsiriX). These imaging data are presented along with vessel measurements for reference. Results An atlas highlighting swine vascular anatomy, with an emphasis on inter-species differences that may influence how studies are conducted and interpreted, was compiled. Conclusions Swine are utilized in broad-reaching fields for preclinical research. While many similarities between human and swine vasculature exist, there are important differences to consider when conducting and interpreting research. This review article highlights these differences and presents accompanying images to inform clinicians gaining experience in swine research.

scholarly journals Influence of spatial structure on protein damage susceptibility: a bioinformatics approach

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Maximilian Fichtner ◽  
Stefan Schuster ◽  
Heiko Stark
Keyword(s):  
Amino Acids ◽  
Molecular Medicine ◽  
Protein Damage ◽  
Aging Research ◽  
Form And Function ◽  
The Core ◽  
And Function ◽  
Thermophilic Organisms ◽  
Damage Susceptibility ◽  
Protein Shell

AbstractAging research is a very popular field of research in which the deterioration or decline of various physiological features is studied. Here we consider the molecular level, which can also have effects on the macroscopic level. The proteinogenic amino acids differ in their susceptibilities to non-enzymatic modification. Some of these modifications can lead to protein damage and thus can affect the form and function of proteins. For this, it is important to know the distribution of amino acids between the protein shell/surface and the core. This was investigated in this study for all known structures of peptides and proteins available in the PDB. As a result, it is shown that the shell contains less susceptible amino acids than the core with the exception of thermophilic organisms. Furthermore, proteins could be classified according to their susceptibility. This can then be used in applications such as phylogeny, aging research, molecular medicine, and synthetic biology.

2. Speaking of God in the Post-Human Era: An Examination of Radical Life Extension in Relation to Key Theological Concepts and Narratives

2018 ◽  
Author(s):  
Kaitlyn Barton
Keyword(s):  
Human Life ◽  
Life Extension ◽  
The Core ◽  
Psychological Suffering ◽  
The Cross ◽  
And Function ◽  
Radical Life Extension ◽  
The Way ◽  
Changing World

Rapid advancements in radical life extension technologies contribute to humanity’s ever-changing world. The normalization of radical life extension technologies would signify that the present era in which biology and evolution act as dictators of human life and health would come to an end, thereby ushering in the age of the post-human. The purpose of this paper is to engage in a theological analysis of how and to what degree the ways in which humanity speaks about God could be changed or influenced if radical life extension becomes normative within society. . It is likely that this powerful technology would have a significant impact on many facets of culture, including the way in which humanity engages with religion, in particular Christianity. To accomplish this, the technology that could potentially support radical life extension, namely nanotechnology and cybernetic immortality, will be explained in terms of their relevance and function. Subsequently, the affects of radical life extension for human life will be addressed. Specifically, the implications of the partial or full eradication of human biological and psychological suffering and death through the use of cybernetic immortality and nanotechnology and will be considered. From there, the core theological concepts and narratives will be analyzed in the context of the potential actualization of radical life extension technology. A focus will be placed on the ethic of loving thy neighbour, Christ’s suffering on the cross, the hope of salvation and the Christian hope of entrance into heaven after death. 

scholarly journals Sec1p Binds to SNARE Complexes and Concentrates at Sites of Secretion

1999 ◽  
Vol 146 (2) ◽  
pp. 333-344 ◽  
Author(s):  
Chavela M. Carr ◽  
Eric Grote ◽  
Mary Munson ◽  
Frederick M. Hughson ◽  
Peter J. Novick
Keyword(s):  
Fluorescent Protein ◽  
Snare Complex ◽  
The Other ◽  
Complex Assembly ◽  
Vesicle Docking ◽  
Neuronal Protein ◽  
The Core ◽  
Target Membrane ◽  
Green Fluorescent ◽  
And Function

Proteins of the Sec1 family have been shown to interact with target-membrane t-SNAREs that are homologous to the neuronal protein syntaxin. We demonstrate that yeast Sec1p coprecipitates not only the syntaxin homologue Ssop, but also the other two exocytic SNAREs (Sec9p and Sncp) in amounts and in proportions characteristic of SNARE complexes in yeast lysates. The interaction between Sec1p and Ssop is limited by the abundance of SNARE complexes present in sec mutants that are defective in either SNARE complex assembly or disassembly. Furthermore, the localization of green fluorescent protein (GFP)-tagged Sec1p coincides with sites of vesicle docking and fusion where SNARE complexes are believed to assemble and function. The proposal that SNARE complexes act as receptors for Sec1p is supported by the mislocalization of GFP-Sec1p in a mutant defective for SNARE complex assembly and by the robust localization of GFP-Sec1p in a mutant that fails to disassemble SNARE complexes. The results presented here place yeast Sec1p at the core of the exocytic fusion machinery, bound to SNARE complexes and localized to sites of secretion.

scholarly journals Research on the Application of Data Visualization Design in CBA League News

2021 ◽  
Vol 236 ◽  
pp. 05078
Author(s):  
Yi Sui ◽  
Honghai Zhang
Keyword(s):  
Data Analysis ◽  
Data Visualization ◽  
User Needs ◽  
Visual Data ◽  
Core Competitiveness ◽  
The Core ◽  
Visualization Design ◽  
Sports News ◽  
The Core Competitiveness ◽  
And Function

In the context of the era of intelligence, the capacity and function of data is expanding, and is playing an irreplaceable role in the field of sports news. This paper studies the data expression mode of sports news. From the point of user needs and the characteristics of visual data, this paper discusses the methods and suggestions of data visualization design in CBA league news, in an attempt to form an intuitive, efficient and convenient visual form of sports news, which can promote the multi-dimensional development of visual symbols in sports news, and promote the progress of data analysis and prediction. The data visualization has become the core competitiveness of sports news.

Rescuing “That Tired Irregular Pearl from Such Lengthy Isolation”

2018 ◽  
pp. 242-258
Author(s):  
Molly A. Warsh
Keyword(s):  
Imperial Authority ◽  
Early American ◽  
Form And Function ◽  
Continuity And Change ◽  
The Core ◽  
Global Connections ◽  
American Experiment ◽  
The Caribbean ◽  
And Function ◽  
Widespread Interest

The conclusion considers the enduring lessons of two centuries of continuity and change in pearl production and circulation. Two hundred years after the Caribbean pearl fisheries’ heyday, the widespread interest in the diversity of form and function that pearls had come to symbolize endured in the personal and imperial imagination. This early American experiment in wealth production honed the governing impulse to contain and categorize objects and subjects by their perceived nature. But neither pearls nor people could ever be easily or entirely controlled. Like pearls, people offer an infinitely varied expression of a single unifying identity and their subjective judgment—as evidenced in assessments of pearl’s value—remained beyond the purview of imperial authority. This essential independence of imagination is embodied by the baroque pearl transformed by a jeweler into exquisite art and the enduring utility of the term beyond pearls as a metaphor for unbounded and irregular expression. Even as many of pearls’ classical associations endured—their sensuality and their association with death, unnatural pairings, and maritime peril—the global connections forged in the post-Columbus years transformed the core of pearls’ identity from simplicity to multiplicity.

Consultation in Clinical Child and Adolescent Psychology

2012 ◽  
pp. 123-138
Author(s):  
Alfred J. Finch ◽  
John E. Lochman ◽  
W. Michael Nelson III ◽  
Michael C. Roberts
Keyword(s):  
Core Competency ◽  
Therapeutic Interventions ◽  
Adolescent Psychology ◽  
Professional Activities ◽  
The Core ◽  
Formal Definitions ◽  
Key Concepts ◽  
Management Techniques ◽  
And Function ◽  
Child And Adolescent Psychology

Chapter 6 outlines the key concepts of the core competency and function of working collaboratively with others to deliver the necessary services through consultation, which can take several forms, including having another professional (physician, nurse, social worker, teacher) conduct an intervention under advice and supervision from the psychologist, providing information about symptoms and screening for behavior problems and how to make a referral, advising juvenile care or detention workers about management techniques, or serving on a collaborative team by offering psychological insights that help create therapeutic interventions for children with certain conditions (e.g., maltreatment, chronic illness). It also provides formal definitions and models of consultation with examples of professional activities in school and pediatric settings.

Histone Variants: The Nexus of Developmental Decisions and Epigenetic Memory

2020 ◽  
Vol 54 (1) ◽  
pp. 121-149 ◽  
Author(s):  
Benjamin Loppin ◽  
Frédéric Berger
Keyword(s):  
Cell Differentiation ◽  
Cell Fate ◽  
Histone Variants ◽  
Epigenetic Memory ◽  
The Core ◽  
Nucleosome Dynamics ◽  
Nucleosome Structure ◽  
Core Histones ◽  
And Function ◽  
The Impact

Nucleosome dynamics and properties are central to all forms of genomic activities. Among the core histones, H3 variants play a pivotal role in modulating nucleosome structure and function. Here, we focus on the impact of H3 variants on various facets of development. The deposition of the replicative H3 variant following DNA replication is essential for the transmission of the epigenomic information encoded in posttranscriptional modifications. Through this process, replicative H3 maintains cell fate while, in contrast, the replacement H3.3 variant opposes cell differentiation during early embryogenesis. In later steps of development, H3.3 and specialized H3 variants are emerging as new, important regulators of terminal cell differentiation, including neurons and gametes. The specific pathways that regulate the dynamics of the deposition of H3.3 are paramount during reprogramming events that drive zygotic activation and the initiation of a new cycle of development.

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