Clinical and Epidemiological Changes in French Soldiers After Deployment: Impact of Doxycycline Malaria Prophylaxis on Body Weight

2021 ◽  
Author(s):  
Emilie Javelle ◽  
Aurélie Mayet ◽  
Rodrigue S Allodji ◽  
Catherine Marimoutou ◽  
Chrystel Lavagna ◽  
...  

ABSTRACT Background Antibiotics are growth promotors used in animal farming. Doxycycline (DOXY) is a tetracycline antibiotic taken daily and continued 1 month after return to protect against malaria during travel and deployment in endemic areas. We evaluated DOXY impact on body weight in military international travelers. Materiel and Methods A prospective cohort analysis was conducted in 2016-2018, recruiting 170 French soldiers before a 4-month assignment overseas. Many clinical data including anthropometric measures by an investigator were collected before and after deployment. Weight gain was defined by an increase of 2% from baseline. The study protocol was supported by the French Armed Forces Health Services and approved by the French ethics committee (IRB no. 2015–A01961–48, ref promoter 2015RC0). Written, informed consent was obtained with signature from each volunteer before inclusion. Results After deployment, 84 soldiers were followed up. Overall, 38/84 (45%) were deployed to Mali with DOXY malaria prophylaxis, and others were deployed to Iraq or Lebanon without malaria prophylaxis according to international recommendations. Body weight increased in 24/84 (30%), of whom 14/24 (58%) were exposed to DOXY. In bivariate analysis, DOXY had a positive but not significant effect on weight gain (P-value = .4). In the final logistic regression model (Fig. 3), weight gain after deployment positively correlated with an increase in waist circumference (odds ratio [OR] 1.23 with 95% CI [1.06-1.47]) suggesting fat gain; with sedentary work (OR 5.34; 95% CI [1.07-31.90]); and with probiotic intake (OR 5.27; 95% CI [1.51-20.40]). Weight impact of probiotics was more important when associated with DOXY intake (OR 6.86; 95% CI [1.52-38.1]; P-value = .016). Conclusions Doxycycline (DOXY) malaria prophylaxis during several months did not cause significant weight gain in soldiers. Further studies are required in older and less sportive traveling populations, and to investigate a cumulative effect over time and recurrent DOXY exposure. Doxycycline (DOXY) may enhance other growth-promoting factors including fatty food, sedentariness, and strain-specific probiotics contained in fermented dairy products which are also used as growth promotors.

2018 ◽  
Author(s):  
Dwi Nur Octaviani Katili

THE EFFECT OF INFANT MASSAGE STIMULATION TOWARDS THE WEIGHT GAIN ON INFANTS WITH LOW BIRTH WEIGHT IN YOGYAKARTADwi Nur Octaviani Katili1, Djaswadi Dasuki2, Retno Mawarti3Universitas Muhammadiyah GorontaloEmail: [email protected]: Infants with low birth weight (LBW) require more nutrients inputs in order to optimize their growth and development. The increase of infants weight is used as the best indicator to determine the growth of infants with LBW. The massage on infant with LBW is a form of stimulus/kinesthetic tactile stimulation as a verbal communication to the infants. It can increase endurance, the activity of the digestive function, and the activity of the vagus nerve.Objective: To determine the benefits of infant massage stimulation as an effective non-medical way in gaining body weight on infants with low birth weight (LBW).Methods: The design of the study is Randomized Controlled Trial. The sampling technique is concecutive sample with the total samples are 15 respondents for each group (treatment and control). The data were analyzed with bivariate analysis stage by using independent t-test with a significance level of p value <0.05 as well as multivariate analysisby using linear regression.Results: The t-test results showed that there is average difference in the gaining of body weight on infants with the low birth weight in the treatment and the control group as big as 53.67 grams with a p value <0.001, 95% CI = -79.02 - (- 28.38).Conclusions: The weight gain on infants with low birth weight who do massage stimulation for 14 days is greater than infants who are not massaged.


2019 ◽  
Author(s):  
Muluken Fekadie Zerihun ◽  
Tabarak Malik ◽  
Yohannes Mulu Ferede ◽  
Tesfahun Bekele ◽  
Yigizie Yeshaw

Abstract Objectives: Depo-Provera is an injectable contraceptive method containing medroxyprogesterone acetate. It has some adverse effects like changes in menstrual pattern, loss in bone mineral density and risk of weight gain. Therefore, this study is aimed at to investigate the effects of Depo-Provera on body weight and blood pressure among Ethiopian women. Institution based cross-sectional study design was conducted from January 2017 to April 2017. Data were analyzed using SPSS version 21 software. Paired t-test, independent t-test and ANOVA were used to evaluate the presence of mean difference and relationship between changes in variables and duration of use of Depo-Provera. P-value ≤ 0.05 were considered as statistically significant. Results: The mean weight and body mass index (BMI) of Depo-Provera users were increased significantly (p=0.02 for mean body weight and p=0.019, for body mass index). There was no significant difference in mean arterial blood pressure (MAP) of Depo-Provera users compared to controls or their respective pretreatment value (p-value=0.85 for Depo-Provera users and 0.67 for non-users). The finding of this study revealed that there is an increased weight gain and BMI among Depo-Provera users compared to non-users, which really requires attention of health professionals and other stake holders.


Author(s):  
Yoon Jung Kim ◽  
Yo Han Lee ◽  
Yun Jeong Lee ◽  
Kyeong Jin Kim ◽  
Sin Gon Kim

Previous cross-sectional studies showed that immigrants from low-income to high-income countries have higher risk of cardiovascular disease and type 2 diabetes mellitus. We investigated the association between weight gain during the resettlement in South Korea and risk of metabolic syndrome (MetS) among North Korean refugees (NKRs) in this cross-sectional study. In total, 932 NKRs aged 20–80 years in South Korea voluntarily underwent health examination from 2008 to 2017. We compared the risk of MetS and its components between the weight gain group (gained ≥5 kg) and the non-weight gain group (gained <5 kg, maintained or lost body weight) during resettlement in South Korea after defection from North Korea. Multiple logistic regression analysis predicted odds ratio of MetS on the basis of weight change, adjusting for covariates and current body mass index (BMI). We also evaluated the difference in body composition of NKRs between two groups. The prevalence of MetS in the weight gain group was 26%, compared to 10% in the non-weight gain group (p-value < 0.001). The weight gain group had a two-fold higher risk of MetS than the non-weight gain group after adjusting for current BMI (odds ratio 1.875, p-value = 0.045). The prevalence of central obesity, impaired fasting glucose, elevated blood pressure, and hypertriglyceridemia were higher in the weight gain group than the non-weight gain group (36% vs. 12%, p-value < 0.001; 32% vs. 19%, p-value < 0.001; 34 vs. 25%, p-value = 0.008; 19% vs. 13%, p-value = 0.025, respectively). The analysis of body composition showed that the percentage of body fat in the weight gain group was higher than in the non-weight gain group, indicating increased fat mass rather than muscle mass in the weight gain group as their body weight increased during resettlement (33.4 ± 6.53% vs. 28.88 ± 7.40%, p < 0.005). Excess weight gain after defection from North Korea increased the risk of MetS among NKRs in South Korea. It is necessary to monitor weight change among NKRs and their effect on their metabolic health in the long term.


2019 ◽  
Vol 14 (2) ◽  
pp. 18-25
Author(s):  
Ilda Lindriyani ◽  
Rully Hevrialni

The prevalence of gestational diabetes mellitus in Indonesia is 1.8% in general pregnancy.One of the prevention of diabetes mellitus in pregnancy is sports interventions, including low impact aerobic exercise, such as swimming, jogging and pregnancy exercises. Benefits of pregnancy exercise reduces the risk of gestational obesity.The purpose of this study was to determine the effect of pregnancy exercise on body weight and blood sugar levels of third trimester pregnant women.The type of the study was a quasy experiment with a post test control group design.The study population was all trimester III pregnant women and the sample was 15 people for each intervention group and the control group was taken using a purposive sampling technique. Data collection in the form of weight measurements after pregnancy exercise which is measured 1 time / week for 3 consecutive weeks and measurement of blood sugar levels before and after pregnancy exercise. Bivariate analysis used the Independent T-test and Mann Whitney U. The results showed the influence of pregnancy exercises on body weight (p-value 0.04,) and there was no effect of pregnancy exercises on decreasing maternal blood sugar levels (p-value 0.404). It is recommended for midwives to socialize and improve health services, namely pregnancy exercises for pregnant women regularly and periodically, and provide counseling about the benefits and effects of pregnancy exercises on weight and blood sugar levels of third trimester pregnant women.


Author(s):  
Tri Widodo ◽  
Sri Sumarmi

Background: The relationship between nutritional status in early life and the risk of chronic diseases in the future development of the child is a critical factor that needs to be considered. The basic factors that can help in this case include thrifty phenotype hypothesis, developmental plasticity, fetal programming and weight gain regulation. This study aims to determine the average increase in weight gain before and after mentoring program. Design and methods: The sample was taken randomly from 191 pregnant women. From number of women mentored, 106 that met the inclusion criteria. Wilcoxon Signed Ranks Test then was used in the data analysis.Results: The results show that the average body weight of women increased 18.94%, while the BMI rose by 7.46%. Mentoring program led to an increase in maternal body weight, indicated with a P-value of 0.000.Conclusions: In conclusion, mentoring program influences bodyweight in pregnant women. Therefore, it is vital to maintain a high nutritional status during pregnancy.


2021 ◽  
Vol 9 (E) ◽  
pp. 415-418
Author(s):  
Putu Candriasih ◽  
Metrys Ndama ◽  
Anna Veronica Pont

Objective: The research objectives were to determine the specific and sensitive intervention model in stunting prevention efforts in the COVID 19 pandemic. Also, to determine the relationship between specific and sensitive interventions on children's nutritional status under five in the COVID-19 pandemic in Stunting Locus Village. Method: This type of research was an observational study with a cross-sectional approach. The population and sample in this study were 35 families with stunting children under five. This study used the chi-square test (p-value <α = 0.05) with SPSS computer software. Results: Nutritional status based on the body-weight/age index, 63% was very underweight and underweight. Based on body-height/age, 28.6% was stunted. Based on body-weight/body-height, 17.1% was severe malnutrition and 40.0 % was malnutrition. The results of the bivariate analysis for specific nutrition interventions with body-weight/age showed p = 0.98, body-weight/age had p = 0.668, body-height/age had p = 0.968, which indicated no significant relationship. Conclusions: Sensitive nutrition intervention showed no relationship between sensitive intervention and children's nutritional status under five


Author(s):  
Cassandra Towns ◽  
Roschelle Heuberger ◽  
Jack Logomarsino ◽  
Arturo Olivera Jr.

Purpose: Evaluate weight maintenance in subjects who lost weight while taking phentermine (PTM). Methods: This study was conducted by utilizing a validated survey to collect self-reported data about weight changes post-PTM use. The survey was sent to 19,986 email addresses of current and former patients of a PTM-based outpatient clinic, located in Chicago, IL; 546 participants completed the survey. Results were analyzed using a variety of techniques. Results: At the time of the survey, 42% of responders maintained all the weight lost while on PTM, and 25.2% had maintained a weight loss of at least 10% of their body weight. The average weight lost and maintained at the time of the survey was 3.75% ± 13.8% of body weight or 8.74 lbs ± 27.45 lbs. Nineteen responders had no net weight change. Fifty-nine responders reported a net weight gain, ranging from 2 to 70 lbs with a mean net weight gain of 16.07 lbs ± 13.87 lbs. The duration of time since discontinuing PTM use had a significant correlation with weight maintenance: r = 0.340, p value = .000. There was no significant correlation between duration of time using PTM and weight maintenance. No correlations were identified between education, income, or ethnicity and weight maintenance. A correlation was identified between weight maintenance and current exercise level: r = 0.218, p value = .000. Conclusions: Although more research is needed, with the results of this study, the investigators suggest that post-PTM use, weight regain is not significantly higher than weight regain through other weight loss programs. In order to achieve long-term weight loss maintenance, it may behoove patients to receive professional guidance about behavior modifications to maintain weight lost, particularly related to exercise and dietary changes. The investigators of this study suggest greater emphasis on behavior modification in patients taking PTM is indicated.


2011 ◽  
Vol 165 (1) ◽  
pp. 11-15 ◽  
Author(s):  
Amanda de Moura Souza ◽  
Rosely Sichieri

BackgroundOvert hypothyroidism is clearly related to body weight gain and greater adiposity, but the range of hormonal change in serum TSH concentration associated with weight gain remains a focus of debate.AimThe aim of this review was to assess studies that evaluated the relationship between anthropometric measures and serum TSH concentration in euthyroid subjects.MethodsStudies held on the Ovid MEDLINE database were searched and original articles published from 2000 to 2010 were included. The literature search was restricted to studies conducted in humans aged 18 years or older and written in English, Spanish, or Portuguese. Studies that evaluated the association between anthropometric measures and serum TSH within the normal range as the primary objective, as well as additional analysis, were included.ResultsA total of 29 studies met the inclusion criteria. Of the 29 studies, 18 showed a positive relationship between measures of adiposity and serum TSH. Despite the plausibility of this association, only two studies reported longitudinal findings. The influence of smoking on the association between serum TSH and anthropometric measures was evaluated in only three studies and remains unclear.ConclusionThus, further longitudinal studies are needed to better understand the mechanisms by which TSH concentration might impact body weight.


2018 ◽  
Vol 5 (3) ◽  
Author(s):  
Bayhakki Bayhakki ◽  
Yesi Hasneli

Inter-Dialytic Weight Gain (IDWG) atau peningkatan berat badan diantara dua tindakan hemodialisis (HD) menjadi salah satu indikator keberhasilan terapi pasien HD. Semakin tinggi IDWG, maka semakin banyak cairan yang menumpuk di dalam tubuh pasien dan semakin berat dampak yang ditimbulkan. Semakin lama seseorang menjalani HD, semestinya semakin banyak yang diketahuinya tentang penyakitnya dan cara mencegah komplikasi sehingga IDWG semestinya semakin turun. Penelitian ini bertujuan untuk mengetahui hubungan antara lama waktu menjalani hemodialisis dengan IDWG. Penelitian korelasional ini dilakukan secara cross sectional dengan melibatkan 34 pasien yang telah menjalani hemodialisis minimal 1 tahun di RSUD Dumai, dapat berkomunikasi secara verbal, dan dapat berdiri untuk menimbang berat badan. Data lama waktu menjalani hemodialisis dilihat dari catatan medis pasien. Adapun IDWG dihitung dalam periode siklus satu minggu menjalani hemodialisis menggunakan timbangan dan dicatat di lembar observasi. Data dianalisis menggunakan uji Spearman. Hasil penelitian menunjukkan median 22 serta nilai minimum dan maksimum yaitu 12 dan 86 bulan. Untuk data IDWG median adalah 3 serta nilai minimum dan maksimum yaitu 1 dan 4,5 kilogram. Analisis hubungan menunjukkan tidak ada hubungan antara lama waktu menjalani hemodialiasis dengan IDWG pada pasien hemodialisis di RSUD Dumai (p value = 0,952) dengan nilai r = 0,01. Diharapkan perawat menganalisis pengetahuan serta pemahaman pasien tentang perlunya mengontrol asupan cairan dan berat badan terutama pada pasien yang telah lama menjalani hemodialisis untuk mencegah kenaikan IDWG yang dapat memperberat kondisi pasien.Kata kunci: Cairan, IDWG, lama hemodialisis AbstractInter-Dialytic Weight Gain (IDWG) becomes an indicator of successful of hemodialysis patients treatment. More IDWG indicates more fluid accumulates in the patient’s body and more impact caused by the excess fluid. This study aimed to investigate relationship between length of undergoing hemodialysis and Inter-Dialytic Weight Gain (IDWG) in Hemodialysis Patients. The study was correlational study with cross sectional approach. Samples of the study were 34 patients. Samples were recruited from hemodialysis patients who have been undergoing hemodialysis at least 1 year in Dumai General Hospital, were able to communicate verbally and to stand up for measuring body weight, and willing to participate in the study. Length of undergoing hemodialysis was taken from medical records. IDWG was measured in one week period of cycle of undergoing hemodialysis using a scale and observation sheet. The result showed the average length of time undergoing hemodialysis was 26.65 months, SD was 15.55, median was 22 and minimum and maximum values were 12 and 86 months respectively. The mean of IDWG was 2.73 kilograms with SD was 1.046, median 3 and minimum and maximum values were 1 and 4.5 kilograms respectively. Result of the study showed that there was no relationship between length of time undergoing hemodialysis and IDWG (p value = 0.952) with r = 0.01. Nurses are expected to further analyze patients’ knowledge as well as understanding about the need to control intake of fluid and body weight to prevent problems caused by kidney damage which suffered by hemodialysis patients.Keywords: Fluid excess, hemodialysis patients, IDWG


2019 ◽  
Author(s):  
Muluken Fekadie Zerihun ◽  
Tabarak Malik ◽  
Yohannes Mulu Ferede ◽  
Tesfahun Bekele ◽  
Yigizie Yeshaw

Abstract Objectives: Depo-Provera is an injectable contraceptive method containing medroxyprogesterone acetate. It has some adverse effects like changes in menstrual pattern, loss in bone mineral density and risk of weight gain. Therefore, this study is aimed at to investigate the effects of Depo-Provera on body weight and blood pressure among Ethiopian women. Institution based cross-sectional study design was conducted from January 2017 to April 2017. Data were analyzed using SPSS version 21 software. Paired t-test, independent t-test and ANOVA were used to evaluate the presence of mean difference and relationship between changes in variables and duration of use of Depo-Provera. P-value ≤ 0.05 were considered as statistically significant. Results: The mean weight and body mass index (BMI) of Depo-Provera users were increased significantly (p=0.02 for mean body weight and p=0.019, for body mass index). There was no significant difference in mean arterial blood pressure (MAP) of Depo-Provera users compared to controls or their respective pretreatment value (p-value=0.85 for Depo-Provera users and 0.67 for non-users). The finding of this study revealed that there is an increased weight gain and BMI among Depo-Provera users compared to non-users, which really requires attention of health professionals and other stake holders.


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