scholarly journals Effects of extended-release eprinomectin on productivity measures in cow–calf systems and subsequent feedlot performance and carcass characteristics of calves

2018 ◽  
Vol 3 (1) ◽  
pp. 273-287 ◽  
Author(s):  
Claire E Andresen ◽  
Dan D Loy ◽  
Troy A Brick ◽  
Lee L Schulz ◽  
Patrick J Gunn

Abstract The objective of this study was to estimate the impact of a single injection of extended-release eprinomectin on economically relevant production variables in beef cows and calves as well as subsequent feedlot health, performance, and carcass traits of calves compared with a traditional, short duration anthelmintic. Animals from 13 cooperator herds across seven states were stratified within herd and assigned to one of two treatments; injectable doramectin (DOR; Dectomax; n = 828) or injectable eprinomection (EPR; Longrange; n = 832). Fecal samples were randomly collected from a subset of cows at both treatment and the end of grazing to evaluate fecal egg count (FEC). Continuous and categorical data were analyzed using the MIXED and GLIMMIX procedures of SAS, respectively. Cow treatment body weight (BW) and final BW were not different (P ≥ 0.40) between treatments. There were no differences (P ≥ 0.12) between treatments in cow ADG, change in BW, or body condition scores during the grazing season. While FEC at treatment did not differ (P = 0.18), cows treated with EPR had lower final FEC at the end of the grazing season (P = 0.02) and a greater reduction of FEC over the grazing season (P = 0.01). Calf treatment BW, weaning BW, and ADG did not differ between treatments (P ≥ 0.34). Incidence of pinkeye tended to be less (P = 0.06) for cows treated with EPR but was not different for calves (P = 0.43). Conception to AI, overall pregnancy rates, and calving interval were not different between treatments (P ≥ 0.45). A subset of calves from each herd was sent to Tri-County Steer Carcass Futurity (TCSCF) feedlot for the finishing phase. Calf BW did not differ at initiation of feeding (P = 0.20). While EPR calves tended to be heavier at reimplantation (P = 0.07), final BW and overall ADG were not different between treatments (P ≥ 0.13). Health records indicated lower morbidity for EPR calves (P = 0.05). Carcass performance including HCW, dressing percent, backfat, KPH, REA, YG, were not different between treatment groups (P ≥ 0.12). However, EPR calves had a greater marbling score, greater average quality grade (P < 0.01), and higher proportion of calves that graded average choice or greater (P = 0.03). Results of this study indicate no difference in cow or preweaning calf performance, however, carcass quality in the feedlot phase was improved. Thus, economic analysis indicates opportunities for return on investment if animals treated with EPR have improved health status and/or carcass quality during the feeding phase.

2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 154-154
Author(s):  
Ashley M Reiner ◽  
Stephanie D Perkins ◽  
Jerica J J Rich ◽  
Emmalee J Northrop ◽  
George A Perry

Abstract Parasitism decreases the nutrients available for cow and fetal/calf performance. The objective of this study was to evaluate the impact of an extended-release dewormer [LongRange® (eprinomectin)] compared to a traditional dewormer [Dectomax® (doramectin)] on fetal/calf performance. Postpartum suckled beef cows (n = 349) were grouped by age and randomly allotted to one of two treatments over a two year period 1) treatment with LongRange at AI and calves treated with Eprinex® or 2) cows and calves treated with Dectomax. In year 2, half of each treatment was switched to the opposite treatment and half remained on the same treatment to result in a 2x2 design (calf sex was included in the statistical model). Cow weight was determined at AI, d60, d135, and d365 (treatment year 2). Calves born in year 2 were weighed at time of AI and at weaning. Pregnancy rates (determined at 60 and 135 d after AI) did not differ in year 1 (P = 0.85, 0.29) or in year 2 (P = 0.44, 0.98). Both treatments lost weight from AI to d60 of the breeding season (P = 0.98); however, there was a weak tendency (P = 0.15) for LongRange cows to gain more from d60 to 135 compared to Dectomax cows. Performance did not differ from d135 to AI in year 2 (P = 0.79). Calves that were in utero during year 1 when their dam received LongRange treatment had increased weight per day of age at year 2 AI (mean calf age =58d) compared to Dectomax treatment (P = 0.05; 2.2 ± 0.09 vs 2.0 ± 0.07kg). Furthermore, year 2 treatment tended (P = 0.09) to impact weight per day of age at weaning (LongRange=1.4 ± 0.03kg, Dectomax=1.3 ± 0.02). There was no year 1 by year 2 interaction (P = 0.87). In summary, administering an extended-release dewormer at AI did not impact pregnancy success, but increased calf performance both at 50d of age and at weaning.


2017 ◽  
Vol 1 (1) ◽  
pp. 54-59 ◽  
Author(s):  
S. R. Edwards ◽  
J. D. Hobbs ◽  
J. T. Mulliniks

Abstract The beef cattle industry tends to focus on selecting production traits with the purpose of maximizing cow-calf performance. One such trait is milking ability, which is considered the primary influence on weaning weight of the calf. Therefore, the objective of this study was to determine the effect of actual milk yield on reproductive performance, circulating blood metabolites, and calf performance in beef cows in the Southeastern US. Over a 2 yr period, data were collected from 237, 3- to 9-yr-old Angus-sired beef cows on 3 research stations in Tennessee. On approximately d 58 and 129 postpartum, 24-hr milk production was measured with a modified weigh-suckle-weigh technique using a milking machine. Subsamples of milk were collected for analysis of milk components. Milk yield data were used to retrospectively classify cows on actual milk yield as High ( ≥ 10 kg/d), Mod (8 to 9 kg/d), or Low ( < 8 kg/d). Cow body weight (BW) and body condition score (BCS) were collected weekly at each location through breeding. Calf BW was recorded at birth, mid-weight at d 58, and weaning. At d 58 and 129 of postpartum, milk yields were different (P < 0.001) among the treatment groups. Cow BW during the entire study were not different (P ≥ 0.22) with increasing milk yield. Timed-AI pregnancy rate were the lowest (P = 0.02) in the High milk producing cows with no difference (P > 0.05) between Low and Mod milk cows. In addition, overall pregnancy rate continued to be the lowest (P = 0.04) in High milk producing cows with the greatest pregnancy rate in Mod milk cows. Calf mid-weight at ∼d 58 was increased (P < 0.001) in calves from Mod and High milking cows. However, calf BW at weaning was not different (P = 0.22) among calves from different milk treatment groups. Results from this study suggest that even in management systems that modify the grazing environments with harvested feedstuffs, high milk production decreases reproductive efficiency. In addition, increasing milk production up to d 129 postpartum did not result in increased calf BW at weaning, indicating that the genetic potential for calf BW at weaning could not be improved with increased genetic potential for milk production.


2021 ◽  
Vol 99 (Supplement_2) ◽  
pp. 30-31
Author(s):  
Elizabeth A Palmer ◽  
Marcelo Vedovatto ◽  
Rhaiza A Oliveira ◽  
Juliana Ranches ◽  
Joao Vendramini ◽  
...  

Abstract This 2-yr study evaluated the effects of winter vs. year-round supplementation of Bos indicus-influenced beef cows on offspring feedlot performance. Brangus cows (82–84 cows/yr) were stratified by BW and BCS (475 ± 67 kg; 4.85 ± 0.73) and randomly assigned to bahiagrass pastures (13–14 cows/pasture). Treatments were randomly assigned to pastures (2 pastures/treatment/yr) and consisted of winter supplementation with molasses (MOL-W), or year-round supplementation with molasses (MOL-Y) or cubes (CUB-Y). Supplements were isocaloric and isonitrogenous (75% TDN, 20% CP; DM basis). Total yearly supplement DM amount was 272 kg/cow for all treatments. At weaning (d 421), 33–35 steers/yr were vaccinated against bovine respiratory disease, transported for 720 miles to the feedlot, penned according to prepartum pasture distribution, and fed the same corn silage-based diet until harvest. Data were analyzed using SAS GLIMMIX procedure. Cow BCS at calving was greater (P < 0.01) for MOL-Y and CUB-Y vs. CON cows. Calving rate, calving date, calf birth weight, and calf preweaning BW did not differ (P ≥ 0.22) among treatments. Steer feedlot BW did not differ (P ≥ 0.36) at time of feedlot entry but was greater (P ≤ 0.05) for MOL-Y and MOL-W steers vs. CUB-Y steers at feedlot exit. Plasma haptoglobin concentrations at feedlot entry were greater (P = 0.05) for CUB-Y vs. CON steers, with MOL-Y steers being intermediate, whereas plasma cortisol concentrations at feedlot entry were greater (P ≤ 0.05) for CUB-Y vs. MOL-Y and MOL-W steers. Marbling score, yield grade, and carcass weight did not differ (P ≥ 0.14), but CON steers had greater fat thickness at the 12th rib than MOL-Y and CUB-Y steers. Hence, year-round supplementation (molasses or cubes) of beef cows increased cow BCS at calving but had minor effects on offspring post-weaning growth and immunity compared to winter supplementation of molasses.


2017 ◽  
Vol 1 (3) ◽  
pp. 367-381 ◽  
Author(s):  
D. B. Burken ◽  
B. L. Nuttelman ◽  
J. L. Gramkow ◽  
A. L. McGee ◽  
K. M. Sudbeck ◽  
...  

Abstract Corn plants were sampled over 2 consecutive years to assess the effects of corn hybrid maturity class, plant population, and harvest time on whole corn plant quality and yield in Nebraska. A finishing experiment evaluated the substitution of corn with corn silage in diets with corn modified distillers grains with solubles (MDGS). The first 2 harvest dates were at the mid- and late-silage harvest times whereas the final harvest was at the grain harvest stage of plant maturity. Whole plant yields increased as harvest time progressed (yr 1 quadratic P < 0.01; yr 2 linear P < 0.01). However, differences in TDN concentration in both years were quite minimal across harvest time, because grain percentage increased but residue NDF in-situ disappearance decreased as harvest time was delayed. In the finishing experiment, as corn silage inclusion increased from 15 to 55% (DM basis) by replacing dry rolled and high moisture corn grain with corn silage in diets containing 40% MDGS, DMI, ADG, and G:F linearly decreased (P ≤ 0.01), with the steers on the 15% corn silage treatment being 1.5%, 5.0%, and 7.7% more efficient than steers on treatments containing 30, 45, and 55% corn silage, respectively. Calculated dietary NEm and NEg decreased linearly as corn silage inclusion increased indicating that net energy values were greater for corn grain than for corn silage. In addition, dressing percentage decreased linearly (P < 0.01) as silage inclusion increased suggesting more fill as silage inclusion increases in diets. Cattle fed greater than 15% corn silage in finishing diets based on corn grain will gain slower and be slightly less efficient and likely require increased days to market at similar carcass fatness and size. When 30% silage was fed with 65% MDGS, DMI, and ADG were decreased (P < 0.01) compared to feeding 30% silage with 40% MDGS suggesting some benefit to including a proportion of corn in the diet. Conversely, when 45% silage was fed with 40% MDGS, ADG, and G:F were greater (P < 0.04) than when 45% silage was fed with just grain implying a greater energy value for MDGS than for corn grain. Substituting corn silage for corn grain in finishing diets decreased ADG and G:F which would increase days to finish to an equal carcass weight; however, in this experiment, increasing corn silage levels with MDGS present reduced carcass fat thickness without significantly decreasing marbling score.


2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 116-116
Author(s):  
Emma T Helm ◽  
Susanne J Lin ◽  
Nicholas Gabler ◽  
Eric R Burrough

Abstract Swine dysentery (SD) induced by Brachyspira hyodysentariae (Bhyo) causes colitis and mucohemorrhagic diarrhea in grow-finish pigs, however little is known about the physiological changes that occur to the gastrointestinal tract during Bhyo infection. Thus, the objective of this study was to evaluate the impact of a Bhyo challenge on intestinal function and integrity of pigs fed two divergent diets. A total of 36 Bhyo negative gilts (24.3 ± 3.6 kg BW) were selected and assigned to one of three treatment groups (n=12 pigs/trt): 1) Bhyo negative, 20% DDGS diet (CON), 2) Bhyo challenged, 20% DDGS diet (DDGS), and 3) Bhyo challenged, 10% DDGS, 5% beet pulp and 5% resistant potato starch diet (RS). Pigs were fed diets 21 days prior to challenge and on days post inoculation (dpi) 0 and 1, pigs were inoculated with Bhyo or sham. Fecal samples were collected for ATTD and pigs were euthanized for colon collection within 72 hours of initial observation of clinical SD, or at the end of the study (dpi 10-16). Tissues were assessed for ex vivo measures of intestinal integrity and mitochondrial function. The challenge resulted in high morbidity, with 88% of DDGS and RS pigs developing clinical SD. Colon transepithelial resistance was increased in DDGS pigs compared with CON and RS pigs (P=0.005), and colon macromolecule permeability was reduced in both DDGS and RS pigs compared with CON pigs (P=0.006), likely due to mucoid discharge. Colonic mitochondrial oxygen consumption was not impacted by treatment (P >0.10). Further, ATTD of DM, OM, N, and GE were reduced in DDGS pigs compared with CON pigs (P< 0.001), whilst nutrient digestibility was not reduced in RS pigs. Taken together, these data show Bhyo does not appear to reduce ex vivo colonic integrity. Further, the RS diet may reduce severity of a Bhyo challenge.


2020 ◽  
Vol 98 (Supplement_2) ◽  
pp. 59-59
Author(s):  
Elizabeth Palmer ◽  
Marcelo Vedovatto ◽  
Juliana Ranches ◽  
Vinicius Gouvea ◽  
Rhaiza Oliveira ◽  
...  

Abstract This study evaluated the growth, immunity, and carcass characteristics of beef steers born to cows offered dried distillers grains (DDG) at different timing during late gestation. Approximately 84 d before calving (d 0), 84 mature Brangus cows were stratified by BW and BCS (422 ± 42 kg; 5.0 ± 0.14) and allocated into 1 of 6 bahiagrass pastures (14 cows/pasture). Treatments were randomly assigned to pastures: 1) no prepartum supplementation (CON); 2) 1 kg/d DDG from d 0 to 84 (LATE84); or 3) 2 kg/d from d 0 to 42 (LATE42). Calves were weaned at 261 ± 23 d of age. At weaning, 38 steers were vaccinated against bovine viral diarrhea virus (BVDV-1) and parainfluenza-3 (PI-3) and transported to a feedlot facility. Steers were penned according to cow prepartum pasture distribution and fed a similar diet until slaughter (d 587). Data were analyzed as complete randomized design using MIXED procedure of SAS, pasture as the experimental unit, treatment as fixed effect, and pasture(treatment) and steer(pasture) as random effects. Steer feedlot BW, ADG, DMI, and G:F did not differ (P ≥ 0.12) among treatments. Plasma haptoglobin concentrations were greater (P ≤ 0.03) for LATE42 and LATE84 vs. CON steers 2 d after feedlot entry. Plasma cortisol and seroconversion for BVDV-1 and PI-3 did not differ (P ≥ 0.15) among treatments. The percentage of carcasses grading Choice did not differ (P = 0.13), but carcasses grading low Choice were greater (P = 0.03) for CON vs. LATE42, with LATE84 being intermediate (91, 40, and 58%, respectively). Thus, prepartum dried distillers grain supplementation to B. indicus-influenced cows did not enhance feedlot growth but had subtle positive impacts on carcass quality and innate immunity in steer progeny. In addition, timing of dried distillers grain supplementation (last 84 d vs. first 42 d of late gestation) did not impact steer post-weaning feedlot performance and carcass quality.


Animals ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 218
Author(s):  
Yousef Abbaslou ◽  
Davood Zahmatkesh ◽  
Ehsan Mahjoubi ◽  
Mehdi Hossein Yazdi ◽  
Hamed Beiranvand ◽  
...  

The positive effects of nucleotide (NU) supplementation in milk replacer have been elucidated in infants and in dairy calves; however, NU addition to whole milk has not been evaluated previously. This study aimed to assess NU supplementation in the whole milk on calf growth and health. Thirty Holstein calves (body weight: 39.1 ± 1.0 kg; 3 d after birth) were randomly assigned to the following treatments: whole milk without any supplementation (NU0), whole milk + 0.5 g/d added a NU-containing supplement to whole milk (NUCS0.5), and whole milk + 1 g/d added a NU-containing supplement to whole milk (NUCS1). Calves were weaned at d 55 and stayed on study until d 75. Calves had free access to feed and water throughout the study. Dry matter intakes (DMI) were similar among treatments (p > 0.05) during the pre-weaning period; however, increasing NU resulted in a linear (p < 0.05) increase in DMI during the post weaning period (2158, 2432, and 2518 g/d for NU0, NUCS0.5, and NUCS1, respectively). Treatments did not affect body weight (BW) at the first and second month of study, but final BW linearly increased as NU was added (87.1, 90.6, and 95.4 kg for NU0, NUCS0.5, and NUCS1, respectively). Neither pre-weaning average daily gain nor post-weaning average daily gain was affected by treatments; accordingly, feed efficiency was similar among treatment groups. Days with loose fecal score were linearly decreased as NU was added to whole milk during the first month of life, while the fecal score did not differ among treatments until the end of the study. No difference was observed in the skeletal growth of calves in the current study. Therefore, it can be concluded that NU supplementation in the whole milk has some beneficial effects on calf performance in terms of final BW, post-weaning DMI, and less days with loose feces.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jane L. Tarry-Adkins ◽  
Susan E. Ozanne ◽  
Catherine E. Aiken

AbstractWe systematically assessed the impact of metformin treatment on maternal pregnancy outcomes. PubMed, Ovid Embase, Medline, Web of Science, ClinicalTrials.gov and Cochrane databases were systematically searched (inception-1st February 2021). Randomised controlled trials reporting pregnancy outcomes in women randomised to metformin versus any other treatment for any indication were included. Outcomes included gestational weight gain (GWG), pre-eclampsia, gestational hypertension, preterm birth, gestational age at delivery, caesarean section, gestational diabetes, glycaemic control, and gastrointestinal side-effects. Two independent reviewers conducted screening, with a third available to evaluate disagreements. Risk-of-bias and GRADE assessments were conducted using Cochrane Risk-of-Bias and GRADE-pro software. Thirty-five studies (n = 8033 pregnancies) met eligibility criteria. GWG was lower in pregnancies randomised to metformin versus other treatments (1.57 kg ± 0.60 kg; I2 = 86%, p < 0.0001), as was likelihood of pre-eclampsia (OR 0.69, 95% CI 0.50–0.95; I2 = 55%, p = 0.02). The risk of gastrointestinal side-effects was greater in metformin-exposed versus other treatment groups (OR 2.43, 95% CI 1.53–3.84; I2 = 76%, p = 0.0002). The risk of other maternal outcomes assessed was not significantly different between metformin-exposed versus other treatment groups. Metformin for any indication during pregnancy is associated with lower GWG and a modest reduced risk of pre-eclampsia, but increased gastrointestinal side-effects compared to other treatments.


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