scholarly journals Getting in the Loop: Regulation of Development in Caulobacter crescentus

2010 ◽  
Vol 74 (1) ◽  
pp. 13-41 ◽  
Author(s):  
Patrick D. Curtis ◽  
Yves V. Brun

SUMMARY Caulobacter crescentus is an aquatic Gram-negative alphaproteobacterium that undergoes multiple changes in cell shape, organelle production, subcellular distribution of proteins, and intracellular signaling throughout its life cycle. Over 40 years of research has been dedicated to this organism and its developmental life cycles. Here we review a portion of many developmental processes, with particular emphasis on how multiple processes are integrated and coordinated both spatially and temporally. While much has been discovered about Caulobacter crescentus development, areas of potential future research are also highlighted.

2021 ◽  
Vol 13 (10) ◽  
pp. 5726
Author(s):  
Aleksandra Wewer ◽  
Pinar Bilge ◽  
Franz Dietrich

Electromobility is a new approach to the reduction of CO2 emissions and the deceleration of global warming. Its environmental impacts are often compared to traditional mobility solutions based on gasoline or diesel engines. The comparison pertains mostly to the single life cycle of a battery. The impact of multiple life cycles remains an important, and yet unanswered, question. The aim of this paper is to demonstrate advances of 2nd life applications for lithium ion batteries from electric vehicles based on their energy demand. Therefore, it highlights the limitations of a conventional life cycle analysis (LCA) and presents a supplementary method of analysis by providing the design and results of a meta study on the environmental impact of lithium ion batteries. The study focuses on energy demand, and investigates its total impact for different cases considering 2nd life applications such as (C1) material recycling, (C2) repurposing and (C3) reuse. Required reprocessing methods such as remanufacturing of batteries lie at the basis of these 2nd life applications. Batteries are used in their 2nd lives for stationary energy storage (C2, repurpose) and electric vehicles (C3, reuse). The study results confirm that both of these 2nd life applications require less energy than the recycling of batteries at the end of their first life and the production of new batteries. The paper concludes by identifying future research areas in order to generate precise forecasts for 2nd life applications and their industrial dissemination.


Author(s):  
Sebastian K. Fixson

Product families and product platforms have been suggested as design strategies to serve heterogeneous markets via mass customization. Numerous, individual cost advantages of these strategies have been identified for various life cycle processes such as product design, manufacturing, or inventory. However, these advantages do not always occur simultaneously, and sometimes even counteract each other. To develop a better understanding of these phenomena, this paper investigates the cost implications of the underlying design decision: the product architecture choice. The investigation includes factors such as product life cycle phases, allocation rules, and cost models, all of which impact the cost analysis results. Based on this investigation, directions for future research on product architecture costing are provided.


2020 ◽  
pp. 104225872097838
Author(s):  
Holger Patzelt ◽  
Rebecca Preller ◽  
Nicola Breugst

While research on entrepreneurial teams has flourished over the past two decades, it has mainly taken a static perspective, neglecting the developments both teams and their ventures undergo over time. To address this issue, we develop a “double life cycle framework” covering entrepreneurial teams’ formation, collaboration, and dissolution phases as well as potential nonlinear sequences of these phases. While this team life cycle is embedded in the venture life cycle, both life cycles can progress independently. We offer research suggestions on entrepreneurial team formation, collaboration, and dissolution in each venture phase, highlighting the role of entrepreneurial teams in advancing their ventures.


2008 ◽  
Vol 380 ◽  
pp. 15-39 ◽  
Author(s):  
Michael C. Connelly ◽  
Jainagesh A. Sekhar

We explore an improved method for the measurement of innovation and innovative activity across long life-cycles especially where patentable technology plays a part in the innovation. In a previous publication we were able to distinguish four stages of a long life cycle. In this article we examine whether the patent life cycle and the production activity life cycle are related. Two conventional schools of thought commonly exist in reference to measurement of technical innovation, one suggesting the use of patents as the best indicator of innovative activity, and the other recommending alternative means, not using patent data. This article proposes a novel method of measurement utilizing yearly patent counts. A model was developed using nine metals whose yearly production activity was correlated with patent counts associated with the same materials. This correlated data was then entered into best-fit equations to obtain fitted patent and activity life cycle curves. Differences in the origins of these fitted curves were interpreted as lags of time in the life cycle of the patent or activity thus allowing for comparisons between patents and innovation activity. The behavior of the number of patents with time was found to be similar to production growth, making patents a measure and representation of technical innovation. In conclusion we were able to categorize the metals into three groups. Group 1, containing nickel and chromium, are metals whose patent activity is driving their production. Group 2, containing aluminum, zinc and copper, are metals in which production is driving the patenting. Group 3, which is composed of the Stage IV metals iron, manganese, molybdenum and tungsten, represents materials that have no current innovative activity that can be measured or correlated to the patent activity. The results suggest a fertile field of future research extending the initial pattern equation model to include R&D, Patents, and Performance, as well as Sales, as innovation activity. Further, the model shows promise for the analysis and assessment of existing and future industrial technology life cycles involving materials, processes, products, software and service innovations.


2020 ◽  
Vol 1 (10) ◽  
pp. 26-35
Author(s):  
E. A. SHUBINA ◽  
◽  
Yu. A. KOMAROVSKY ◽  
A. V. MERKUSHEV ◽  
◽  
...  

The article is devoted to the study of the largest mergers and acquisitions (M&A, “Mergers & Acquisitions”) in Russia for 2017–2019. (the acquired block of shares is not less than 99%). The concept of life cycles of organizations and theoretical aspects of mergers and acquisitions are described. The stages of the life cycle of the merged and reorganized companies, the goals of mergers and acquisitions, depending on the stages of the life cycle are analyzed.


Author(s):  
Valeriy S. Gerasimov ◽  
Vladimir I. Ignatov ◽  
Konstantin G. Sovin

According to forecasts for 2022, the number of self-propelled agricultural machinery that will fail will be about 100 thousand units. This will have a significant impact on the overall productivity in the field of agricultural production and will require additional financial costs for effective resource-saving environmental-oriented utilization of agricultural machinery with the maximum recovery of secondary resources in the processing of its components. (Research purpose) The research purpose is considering the main life cycles of machinery, including agricultural, and determining the possibility of obtaining secondary resources in the recycling of components of machinery and equipment. (Materials and methods) The authors found that the establishment of an industry-wide recycling system would allow the reuse of usable and recovered parts obtained from decommissioned equipment, as well as receive additional funding from the sale of secondary resources. The authors have found that for the functioning of the whole system, it is necessary to work with a large amount of data related to the ongoing recycling processes, as well as constantly monitor changes in the state and properties of materials. They also found that the maximum use of digital technology is the only way to combine all these requirements and make the system work. (Results and discussion) The article reviews the key points of the use of life cycle method for equipment, including agricultural, reviews the state of machine and tractor park of agro-industrial complex, shows the possibility of using resource-saving ecologically oriented branch system of recycling of agricultural machinery, as well as the movement of waste and material flows in the processing components of utilized machines. (Conclusion) The article presents recommendations on the possibility of efficient disposal of equipment, including agricultural, with the maximum recovery of secondary resources from recycled waste.


2020 ◽  
Vol 40 (6) ◽  
pp. 825-832 ◽  
Author(s):  
Miku Yabuta ◽  
Jens T Høeg ◽  
Shigeyuki Yamato ◽  
Yoichi Yusa

Abstract Although parasitic castration is widespread among rhizocephalan barnacles, Boschmaella japonica Deichmann & Høeg, 1990 does not completely sterilise the host barnacle Chthamalus challengeri Hoek, 1883. As little information is available on the relationships with the host in “barnacle-infesting parasitic barnacles” (family Chthamalophilidae), we studied the life cycles of both B. japonica and C. challengeri and the effects of the parasite on the host reproduction. Specimens of C. challengeri were collected from an upper intertidal shore at Shirahama, Wakayama, western Japan from April 2017 to September 2018 at 1–3 mo intervals. We recorded the body size, number of eggs, egg volume, and the presence of the parasite for each host. Moreover, settlement and growth of C. challengeri were followed in two fixed quadrats. Chthamalus challengeri brooded from February to June. The prevalence of B. japonica was high (often exceeded 10%) from April to July, and was rarely observed from September to next spring. The life cycle of the parasite matched well with that of the host. The parasite reduced the host’s brooding rate and brood size, to the extent that no hosts brooded in 2018.


Agronomy ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1565
Author(s):  
María Belén D’Amico ◽  
Guillermo R. Chantre ◽  
Guillermo L. Calandrini ◽  
José L. González-Andújar

Population models are particularly helpful for understanding long-term changes in the weed dynamics associated with integrated weed management (IWM) strategies. IWM practices for controlling L. rigidum are of high importance, mainly due to its widespread resistance that precludes chemical control as a single management method. The objective of this contribution is to simulate different IWM scenarios with special emphasis on the impact of different levels of barley sowing densities on L. rigidum control. To this effect, a weed–crop population model for both L. rigidum and barley life cycles was developed. Our results point out: (i) the necessity of achieving high control efficiencies (>99%), (ii) that the increase of twice the standard sowing density of barley resulted in a reduction of 23.7% of the weed density, (iii) non-herbicide-based individual methods, such as delayed sowing and weed seed removal at harvest, proved to be inefficient for reducing drastically weed population, (iv) the implementation of at least three control tactics (seed removal, delay sowing and herbicides) is required for weed infestation eradication independently of the sowing rate, and (v) the effect of an increase in the sowing density is diluted as a more demanding weed control is reached. Future research should aim to disentangle the effect of different weed resistance levels on L. rigidum population dynamics and the required efficiencies for more sustainable IWM programs.


2021 ◽  
Vol 13 (15) ◽  
pp. 8427
Author(s):  
Bahareh Nikmehr ◽  
M. Reza Hosseini ◽  
Jun Wang ◽  
Nicholas Chileshe ◽  
Raufdeen Rameezdeen

This article provides a picture of the latest developments in providing BIM-based tools for construction and demolition waste (CDW) management. The coverage and breadth of the literature on offering BIM-based tools and technologies for dealing with CDW throughout the whole life cycle of construction are investigated, and gaps are identified. Findings reveal that, although various BIM-based technologies are closely associated with CDW, much of the existing research on this area has focused on the design and construction phase; indeed, the problem of CDW in post-construction stages has received scant attention. Besides, the now available tools and technologies are lacking in cross-phase insights into project waste aspects and are weak in theoretical rigor. This article contributes to the field by identifying the intellectual deficiencies in offering BIM-based tools and technologies when dealing with CDW. So, too, it points to major priorities for future research on the topic. For practitioners, the study provides a point of reference and raises awareness in the field about the most advanced available BIM-based technologies for dealing with CDW problems.


2021 ◽  
Vol 13 (5) ◽  
pp. 2525
Author(s):  
Camila López-Eccher ◽  
Elizabeth Garrido-Ramírez ◽  
Iván Franchi-Arzola ◽  
Edmundo Muñoz

The aim of this study is to assess the environmental impacts of household life cycles in Santiago, Chile, by household income level. The assessment considered scenarios associated with environmental policies. The life cycle assessment was cradle-to-grave, and the functional unit considered all the materials and energy required to meet an inhabitant’s needs for one year (1 inh/year). Using SimaPro 9.1 software, the Recipe Midpoint (H) methodology was used. The impact categories selected were global warming, fine particulate matter formation, terrestrial acidification, freshwater eutrophication, freshwater ecotoxicity, mineral resource scarcity, and fossil resource scarcity. The inventory was carried out through the application of 300 household surveys and secondary information. The main environmental sources of households were determined to be food consumption, transport, and electricity. Food consumption is the main source, responsible for 33% of the environmental impacts on global warming, 69% on terrestrial acidification, and 29% on freshwater eutrophication. The second most crucial environmental hotspot is private transport, whose contribution to environmental impact increases as household income rises, while public transport impact increases in the opposite direction. In this sense, both positive and negative environmental effects can be generated by policies. Therefore, life-cycle environmental impacts, the synergy between policies, and households’ socio-economic characteristics must be considered in public policy planning and consumer decisions.


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