scholarly journals Ability of Different Measures of Adiposity to Identify High Metabolic Risk in Adolescents

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Carla Moreira ◽  
Rute Santos ◽  
Susana Vale ◽  
Paula C. Santos ◽  
Sandra Abreu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hdl Cholesterol ◽  
Individual Risk ◽  
Metabolic Risk ◽  
Operating Characteristics ◽  
Pubertal Stage ◽  
Cross Sectional ◽  
Screening Performance ◽  
Z Scores ◽  
The Individual

Introduction. This study aimed to evaluate the screening performance of different measures of adiposity: body mass index (BMI), waist circumference (WC), and waist-to-height ratio (WHtR) for high metabolic risk in a sample of adolescents.Methods. A cross-sectional school-based study was conducted on 517 adolescents aged 15–18, from the Azorean Islands, Portugal. We measured fasting glucose, insulin, total cholesterol (TC), HDL-cholesterol, triglycerides, and systolic blood pressure. HOMA and TC/HDL-C ratio were calculated. For each of these variables, a Z-score was computed by age and sex. A metabolic risk score (MRS) was constructed by summing the Z-scores of all individual risk factors. High risk was considered when the individual had ≥1SD of this score. Receiver-operating characteristics (ROC) were used.Results. Linear regression analyses showed that, after adjusting for age and pubertal stage, all different measures of adiposity are positively and significantly associated with MRS in both sexes, with exception of WHtR for boys. BMI, WC, and WHtR performed well in detecting high MRS, indicated by areas under the curve (AUC), with slightly greater AUC for BMI than for WC and WHtR in both sexes.Conclusion. All measures of adiposity were significantly associated with metabolic risk factors in a sample of Portuguese adolescents.

scholarly journals Individual and Environmental Factors Associated with Recurrent Falls in Elderly Patients Hospitalized after Falls

2020 ◽  
Vol 17 (7) ◽  
pp. 2441
Author(s):  
Hai Minh Vu ◽  
Long Hoang Nguyen ◽  
Huong Lan Thi Nguyen ◽  
Giang Thu Vu ◽  
Cuong Tat Nguyen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Environmental Factors ◽  
Elderly Patients ◽  
Environmental Conditions ◽  
Social Consequences ◽  
Individual Risk ◽  
Cross Sectional ◽  
Factors Associated ◽  
Recurrent Falls ◽  
The Individual

Falls and recurrent falls cause great health and social consequences in older people. However, these problems are poorly understood in Vietnam. A cross-sectional study was performed at seven hospitals in Thai Binh province, Vietnam, to investigate the individual and environmental factors associated with recurrent falls among elderly patients hospitalized due to fall injuries in Vietnam. A history of recurrent falls within the last 12 months, sociodemographic, health, and clinical characteristics, as well as environmental conditions, were obtained via self-reported interviews. Multivariate logistic and Poisson regression models were used to identify associated factors. Overall, the mean fall episodes in the last 12 months were 1.8 (Standard deviation—SD = 1.2) episodes, and the 12-month prevalence of recurrent falls was 40.5%. The individual risk factors included not receiving fall prevention guidelines, walking with devices, loss of sensation in hand or foot, and using pain relief medications. The environmental risk factors comprised having too-high stairs and not having dry, clean, and nonslippery bathrooms. This study highlights a significantly high 12-month prevalence of recurrent falls in older patients hospitalized after falls in Vietnam. Moreover, regular assessments of functional disabilities and hazardous environmental conditions, as well as the provision of prevention programs, have potential to prevent falls and recurrent falls.

The efficacy of combining several risk factors as a screening test

2005 ◽  
Vol 12 (4) ◽  
pp. 197-201 ◽  
Author(s):  
Nicholas J Wald ◽  
Joan K Morris ◽  
Simon Rish
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
False Positive ◽  
Detection Rate ◽  
False Positive Rate ◽  
Individual Risk ◽  
Detection Rates ◽  
Screening Performance ◽  
Positive Rate ◽  
The Individual

Objective: To determine the quantitative effect on overall screening performance (detection rate for a given false-positive rate) of using several moderately strong, independent risk factors in combination as screening markers. Setting: Theoretical statistical analysis. Methods: For the purposes of this analysis, it was assumed that all risk factors were independent, had Gaussian distributions with the same standard deviation in affected and unaffected individuals and had the same screening performance. We determined the overall screening performance associated with using an increasing number of risk factors together, with each risk factor having a detection rate of 10%, 15% or 20% for a 5% false-positive rate. The overall screening performance was estimated as the detection rate for a 5% false-positive rate. Results: Combining the risk factors increased the screening performance, but the gain in detection at a constant false-positive rate was relatively modest and diminished with the addition of each risk factor. Combining three risk factors, each with a 15% detection rate for a 5% false-positive rate, yields a 28% detection rate. Combining five risk factors increases the detection rate to 39%. If the individual risk factors have a detection rate of 10% for a 5% false-positive rate, it would require combining about 15 such risk factors to achieve a comparable overall detection rate (41%). Conclusion: It is intuitively thought that combining moderately strong risk factors can substantially improve screening performance. For example, most cardiovascular risk factors that may be used in screening for ischaemic heart disease events, such as serum cholesterol and blood pressure, have a relatively modest screening performance (about 15% detection rate for a 5% false-positive rate). It would require the combination of about 15 or 20 such risk factors to achieve detection rates of about 80% for a 5% false-positive rate. This is impractical, given the risk factors so far discovered, because there are too few risk factors and their associations with disease are too weak.

scholarly journals The Hamstrings: Anatomic and Physiologic Variations and Their Potential Relationships With Injury Risk

2021 ◽  
Vol 12 ◽  
Author(s):  
José Afonso ◽  
Sílvia Rocha-Rodrigues ◽  
Filipe M. Clemente ◽  
Michele Aquino ◽  
Pantelis T. Nikolaidis ◽  
...  
Keyword(s):  
Risk Factors ◽  
Injury Risk ◽  
Individual Characteristics ◽  
Individual Risk ◽  
Modifiable Risk Factors ◽  
Fiber Types ◽  
Cross Sectional ◽  
Exercise Interventions ◽  
Age Related ◽  
The Individual

The incidence and recurrence of hamstrings injuries are very high in sports, posing elevated performance and financial-related costs. Attempts to identify the risk factors involved in predicting vulnerability to hamstrings injury is important for designing exercise-based programs that aim to mitigate the rate and severity of hamstrings injuries and improve rehabilitation strategies. However, research has shown that non-modifiable risk factors may play a greater role than modifiable risk factors. Recognizing non-modifiable risk factors and understanding their implications will afford the prescription of better suited exercise programs, i.e., that are more respectful of the individual characteristics. In a nutshell, non-modifiable risk factors can still be acted upon, even if indirectly. In this context, an underexplored topic is how intra and inter- individual anatomic and physiologic variations in hamstrings (e.g., muscle bellies, fiber types, tendon length, aponeurosis width, attachment sites, sex- and age-related differences) concur to alter hamstrings injuries risk. Some anatomic and physiologic variations may be modifiable through exercise interventions (e.g., cross-sectional area), while others may not (e.g., supernumerary muscle bellies). This apparent dichotomy may hide a greater complexity, i.e., there may be risk factors that are partially modifiable. Therefore, we explored the available information on the anatomic variations of the hamstrings, providing a deeper insight into the individual risk factors for hamstrings injuries and contributing with better knowledge and potential applications toward a more individualized exercise prescription.

scholarly journals Relationships of Cardiorespiratory Fitness with Metabolic Risk Factors, Inflammation, and Liver Transaminases in Overweight Youths

2010 ◽  
Vol 2010 ◽  
pp. 1-5 ◽  
Author(s):  
Dominique Bouglé ◽  
Gautier Zunquin ◽  
Bruno Sesbouë ◽  
Jean-Pierre Sabatier
Keyword(s):  
Risk Factors ◽  
Insulin Resistance ◽  
Blood Pressure ◽  
Hdl Cholesterol ◽  
Metabolic Risk Factors ◽  
Metabolic Risk ◽  
Pubertal Stage ◽  
Continuous Increase ◽  
Obese Youth ◽  
Liver Transaminases

The aim of this study was to assess the relationships of fatness and fitness with metabolic risk factors, including liver transaminases and inflammation in obese youth, taking in account gender, age, and pubertal stage. 241 children were studied (135 girls), age11.9±2.2years (x±SD), Body Mass Indexzscore5.4±2.7. For girls,VO2maxwas significantly associated with insulin (P=.001), Insulin resistance (HOMA-IR) (P=.005), and ALT (P=.012); a relationship was displayed between fibrinogen and age and % fat mass (FM) (P=.008); for boys, relationships were found betweenVO2maxand diastolic blood pressure and triglycerides; independent associations were also found between age and insulin, HOMA-IR and HDL cholesterol; fibrinogen and sedimentation rate were related (P≤.004) with %FM. Their relationships are observed from young age and increase with the continuous increase of factors. This supports the need to treat overweight as soon as it is detected; improving CRF is one of the ways which could be used to prevent the complications of obesity.

Abstract P035: Association Between Caregiver and Child Metabolic Risk Factors: Hispanic Community Health Study/Study of Latino (SOL) Youth

Circulation ◽  
2016 ◽  
Vol 133 (suppl_1) ◽  
Author(s):  
Mercedes R Carnethon ◽  
Srikant I Bangdiwala ◽  
A. Talavera ◽  
Krista Perreira ◽  
Samantha Reina ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Age Of Onset ◽  
Normal Weight ◽  
Metabolic Risk Factors ◽  
Health Study ◽  
Individual Risk ◽  
Metabolic Risk ◽  
Cross Sectional ◽  
Adult Age

Background: There is limited prior research on the association of metabolic risk factors between youth and their caregivers within Latino families despite the high burden of obesity and the young age of onset of metabolic disorders. Hypothesis: Obesity and metabolic risk factors are correlated between youth and their caregivers. Methods: SOL Youth is a cross-sectional ancillary study of boys and girls ages 8 to 16 years old whose parents/caregivers participated in the HCHS/SOL. We studied 728 boys, 738 girls and 1,020 caregivers (86% women) who completed a clinical examination. Body mass index (BMI), waist circumference, systolic and diastolic blood pressure, fasting glucose, hemoglobin A1c (HbA1c) and lipids (total-, HDL-, and LDL- cholesterol and triglycerides) were measured. Obesity was determined as > 95 th age- and gender- specific percentile of BMI in youth and BMI > 30 kg/m 2 in adults. We used weighted logistic regression to determine the odds of obesity in youth when caregivers were obese and we tested the association of each individual risk factor in caregivers with the same risk factor among youth using weighted linear regression. All models were adjusted for field center, youth age and ancestry and adult age, gender and education levels. Results: On average, boys and girls were 12 years old and caregivers were 41 years old. When caregivers were obese (vs. normal weight), girls and boys were 1.5 (95% CI: 0.92, 2.43) and 3.9 (95% CI: 2.44, 6.29) times more likely to be obese, respectively. Among girls, measures of adiposity, HbA1c, SBP and lipids (except triglycerides) were each positively associated with those same measures among caregivers (Table). Among boys, all measures except glucose and HbA1c were positively associated with caregiver measures. Conclusions: There were notable differences by gender in the odds of obesity among youth when a caregiver was also obese. Strong correlations between caregiver and youth metabolic risk factors underscore the need for family based interventions.

scholarly journals Cardio-Metabolic Risk Factors in Scottish South Asian and Caucasian Youth

2021 ◽  
Vol 18 (9) ◽  
pp. 4667
Author(s):  
Meizi Wang ◽  
Jianhua Ying ◽  
Ukadike Chris Ugbolue ◽  
Duncan S. Buchan ◽  
Yaodong Gu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Waist Circumference ◽  
Body Mass ◽  
South Asian ◽  
Metabolic Risk Factors ◽  
Individual Risk ◽  
Metabolic Risk ◽  
Asian Adolescents ◽  
Individual Risk Factors

(1) Background: Scotland has one of the highest rates of obesity in the Western World, it is well established that poor weight profiles, and particularly abdominal obesity, is strongly associated with Type II diabetes and cardiovascular diseases. Whether these associations are apparent in ethnic population groups in Scotland is unclear. The purpose of this study was to examine the associations between different measures of fatness with clustered cardio metabolic risk factors between Scottish South Asian adolescents and Scottish Caucasian adolescents; (2) Methods: A sample of 208 Caucasian adolescents and 52 South Asian adolescents participated in this study. Stature, waist circumference, body mass index, blood pressure, physical activity, and cardiovascular disease (CVD) risk were measured; (3) Results: Significant, partial correlations in the South Asian cohort between body mass index (BMI) and individual risk factors were generally moderate. However, correlations between Waist circumference (WC) and individual risk factors were significant and strong. In the Caucasian cohort, a significant yet weak correlation between WC and total cholesterol (TG) was noted although no other associations were evident for either WC or BMI. Multiple regression analysis revealed that both BMI and WC were positively associated with CCR (p < 0.01) in the South Asian group and with the additional adjustment of either WC or BMI, the independent associations with clustered cardio-metabolic risk (CCR) remained significant (p < 0.005); (4) Conclusions: No positive relationships were found between BMI, WC, and CCR in the Caucasian group. Strong and significant associations between measures of fatness and metabolic risk were evident in Scottish South Asian adolescents.

scholarly journals Eating behavior affects cardio-metabolic risk in high school teenagers in a developing country

2020 ◽  
Vol 29 (1) ◽  
pp. 71-81
Author(s):  
Rita Suhadi ◽  
Phebe Hendra ◽  
Dita Maria Virginia ◽  
Christianus Heru Setiawan
Keyword(s):  
Risk Factors ◽  
Heart Rate ◽  
Waist Circumference ◽  
Eating Behavior ◽  
Eating Behaviors ◽  
Metabolic Risk Factors ◽  
Metabolic Risk ◽  
Cross Sectional ◽  
Male Subjects ◽  
Female Subjects

BACKGROUND Modernization negatively changes lifestyle, characterized by excessive eating and reduced energy consumption, and concurrently increases the cardiometabolic risk. This study was aimed to evaluate the association between eating behavior and cardio-metabolic risk factors including body mass index (BMI) in percentile, blood pressure (BP) in percentile, waist circumference, and heart rate in total subjects and gender sub-groups. METHODS This analytical cross-sectional study was done from July to November 2018. High schools in four provinces of Indonesia and students were selected using purposive sampling. Subjects’ profiles were collected from interview and cardio-metabolic parameters were measured at the study sites. Data were analyzed with chi-square and independent t-test. RESULTS Subjects who were overweight/obese and had high BP accounted for 27.1% and 9.3–12.0% of the total subjects (n = 768), respectively. Subjects who having breakfast tended to have lower BMI (p = 0.006), and the lower consumption of western meals had lower heart rate (p = 0.02). Male subjects had more meal frequency and had less quantity of snacks than female subjects (p<0.001). Male subjects with routine intake of vegetables had low heart rate (p = 0.03). Female subjects with routine breakfast had better BMI (p<0.001), and lower diastolic BP (p = 0.004) and waist circumference (p = 0.02), whereas those who consumed Western meals had higher heart rate (p = 0.046) and waist circumference (p = 0.001). CONCLUSIONS Eating behaviors are likely to affect cardio-metabolic risk factors, and the effects vary within gender groups.

scholarly journals Vitamin D status and associated metabolic risk factors among North Korean refugees in South Korea: a cross-sectional study

BMJ Open ◽  
2015 ◽  
Vol 5 (11) ◽  
pp. e009140 ◽  
Author(s):  
Kyeong Jin Kim ◽  
Yoon Jung Kim ◽  
Sun Hwa Kim ◽  
Jee Hyun An ◽  
Hye Jin Yoo ◽  
...  
Keyword(s):  
Risk Factors ◽  
Vitamin D ◽  
South Korea ◽  
Cross Sectional Study ◽  
Metabolic Risk Factors ◽  
Metabolic Risk ◽  
Vitamin D Status ◽  
Sectional Study ◽  
Cross Sectional ◽  
North Korean Refugees

scholarly journals Rheumatoid Arthritis Impacts on the Independent Relationships between Circulating Adiponectin Concentrations and Cardiovascular Metabolic Risk

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Patrick H. Dessein ◽  
Gavin R. Norton ◽  
Margaret Badenhorst ◽  
Angela J. Woodiwiss ◽  
Ahmed Solomon
Keyword(s):  
Rheumatoid Arthritis ◽  
Risk Factors ◽  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Hdl Cholesterol ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Metabolic Risk ◽  
Black African ◽  
Pressure Independent

Adiponectin and leptin are likely involved in the pathophysiology of rheumatoid arthritis (RA) and therefore potential new therapeutic targets. Adiponectin inhibition could be expected to enhance cardiovascular metabolic risk. However, it is unknown whether RA changes the influence of adipokines on cardiovascular metabolic risk. We determined whether RA impacts on the independent relationships of circulating leptin and adiponectin concentrations with cardiovascular risk factors and carotid intima-media thickness (cIMT) in 277 black African subjects from a developing population; 119 had RA. RA impacted on the relationships of adiponectin concentrations with lipid concentrations and blood pressure, independent of confounders including adiposity (interactionP<0.05). This translated into an association of adiponectin concentrations with more favorable lipid variables including HDL cholesterol (P=0.0005), non-HDL cholesterol (P=0.007), and triglyceride (P=0.005) concentrations, total cholesterol-HDL cholesterol (P=0.0002) and triglycerides-HDL cholesterol (P=0.0003) ratios, and higher systolic (P=0.0006), diastolic (P=0.0004), and mean blood pressure (P=0.0007) in RA but not non-RA subjects. Leptin was not associated with metabolic risk after adjustment for adiposity. The cIMT did not differ by RA status, and adipokine concentrations were unrelated to atherosclerosis. This study suggests that leptin and adiponectin inhibition may not alter overall cardiovascular risk and disease in RA.

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