scholarly journals Propolis and Its Potential to Treat Gastrointestinal Disorders

2018 ◽  
Vol 2018 ◽  
pp. 1-12 ◽  
Author(s):  
Luisa Mota da Silva ◽  
Priscila de Souza ◽  
Soad K. Al Jaouni ◽  
Steve Harakeh ◽  
Shahram Golbabapour ◽  
...  
Keyword(s):  
Significant Proportion ◽  
Gastrointestinal Diseases ◽  
Treatment And Prevention ◽  
Pathological Conditions ◽  
Therapeutic Value ◽  
High Incidence ◽  
Different Types ◽  
Scientific Papers ◽  
Aromatic Substance

There are a number of disorders that affect the gastrointestinal tract. Such disorders have become a global emerging disease with a high incidence and prevalence rates worldwide. Inflammatory and ulcerative processes of the stomach or intestines, such as gastritis, ulcers, colitis, and mucositis, afflict a significant proportion of people throughout the world. The role of herbal-derived medicines has been extensively explored in order to develop new effective and safe strategies to improve the available gastrointestinal therapies that are currently used in the clinical practice. Studies on the efficacy of propolis (a unique resinous aromatic substance produced by honeybees from different types of species of plants) are promising and propolis has been effective in the treatment of several pathological conditions. This review, therefore, summarizes and critiques the contents of some relevant published scientific papers (including those related to clinical trials) in order to demonstrate the therapeutic value of propolis and its active compounds in the treatment and prevention of gastrointestinal diseases.

scholarly journals Creolised Text in Mass Media: Principles of Effective Decoding

2019 ◽  
Vol 8 (1) ◽  
pp. 147-163
Author(s):  
Victor Shaklein ◽  
Maria Belova ◽  
Svetlana Mikova
Keyword(s):  
Mass Media ◽  
Information Visualization ◽  
Mass Communication ◽  
Printed Media ◽  
Sign Systems ◽  
Different Types ◽  
Scientific Papers ◽  
Psychology Literature ◽  
Iconic Sign

Arising and active development of innovative information channels, forming net thinking, require non-standard forms of presenting material in mass media. One of the solutions to this problem is increasing the number of creolised texts not only in electronic, but in printed media as well. Such texts containing verbal (heading, subscript, text comprising of more than one sentence) and non-verbal (image, scheme, table, font, colour) parts are widely spread in mass media because they allow the reader to precisely understand the author’s intention and the intention can be expressed in an implicit way. Such texts correspond to mass communication general trends towards information visualization, raising the effectiveness of the text impact on audience thanks to double coding, compact presentation of the material. These are the reasons of growing scientific interest in creolized texts in psychology, literature studies, linguistics, journalism. However, the terminology of the scientific sphere is not conventional: different terms “creolized text”, “semantically complicated text”, “polycode text”, etc. are all used in similar meanings in scientific papers. The authors of the article characterize terms used in Russian and foreign articles and monographs, assess their frequency and semantic scope. The specific features of creolized texts are pointed out, different types of such texts depending on metagraphic and iconic sign systems included in them are described. We distinguish three phases in reading such texts (preliminary stage, organised perception, final stage) and the role of visual and verbal components in the process. By the example of caricatures we show the importance of background knowledge for adequate decoding of creolized texts. Linguistic and cultural universals are an optimal source of objects whose meaning is evident to the representative of a certain culture. This makes the creolized text decoding easier in linguistic culture of its origin. On the other hand, texts based on linguistic and cultural universalia (realia, idioms, homophones, homographs, etc.) present extra difficulties for non-natives. The material of the research is caricatures of the late 20th — early 21st centuries by A.Merinov. Each of the caricatures is based on a certain linguistic and cultural universal.

scholarly journals Autophagy in endocrine tumors

2015 ◽  
Vol 22 (4) ◽  
pp. R205-R218 ◽  
Author(s):  
Andrea Weckman ◽  
Fabio Rotondo ◽  
Antonio Di Ieva ◽  
Luis V Syro ◽  
Henriett Butz ◽  
...  
Keyword(s):  
Treatment Efficacy ◽  
Endocrine Tumors ◽  
Dependent Manner ◽  
Endocrine Glands ◽  
Cell Type ◽  
Pathological Conditions ◽  
Tumor Survival ◽  
Different Types ◽  
Intracellular Process

Autophagy is an important intracellular process involving the degradation of cytoplasmic components. It is involved in both physiological and pathological conditions, including cancer. The role of autophagy in cancer is described as a ‘double-edged sword,’ a term that reflects its known participation in tumor suppression, tumor survival and tumor cell proliferation. Available research regarding autophagy in endocrine cancer supports this concept. Autophagy shows promise as a novel therapeutic target in different types of endocrine cancer, inhibiting or increasing treatment efficacy in a context- and cell-type-dependent manner. At present, however, there is very little research concerning autophagy in endocrine tumors. No research was reported connecting autophagy to some of the tumors of the endocrine glands such as the pancreas and ovary. This review aims to elucidate the roles of autophagy in different types of endocrine cancer and highlight the need for increased research in the field.

scholarly journals Functional Role of Non-Muscle Myosin II in Microglia: An Updated Review

2021 ◽  
Vol 22 (13) ◽  
pp. 6687
Author(s):  
Chiara Porro ◽  
Antonio Pennella ◽  
Maria Antonietta Panaro ◽  
Teresa Trotta
Keyword(s):  
Nervous System ◽  
Atp Hydrolysis ◽  
Myosin Ii ◽  
Cellular Functions ◽  
Pathological Conditions ◽  
Different Types ◽  
The Central Nervous System ◽  
Muscle Myosin ◽  
Pro Inflammatory Cytokines

Myosins are a remarkable superfamily of actin-based motor proteins that use the energy derived from ATP hydrolysis to translocate actin filaments and to produce force. Myosins are abundant in different types of tissues and involved in a large variety of cellular functions. Several classes of the myosin superfamily are expressed in the nervous system; among them, non-muscle myosin II (NM II) is expressed in both neurons and non-neuronal brain cells, such as astrocytes, oligodendrocytes, endothelial cells, and microglia. In the nervous system, NM II modulates a variety of functions, such as vesicle transport, phagocytosis, cell migration, cell adhesion and morphology, secretion, transcription, and cytokinesis, as well as playing key roles during brain development, inflammation, repair, and myelination functions. In this review, we will provide a brief overview of recent emerging roles of NM II in resting and activated microglia cells, the principal regulators of immune processes in the central nervous system (CNS) in both physiological and pathological conditions. When stimulated, microglial cells react and produce a number of mediators, such as pro-inflammatory cytokines, free radicals, and nitric oxide, that enhance inflammation and contribute to neurodegenerative diseases. Inhibition of NM II could be a new therapeutic target to treat or to prevent CNS diseases.

scholarly journals Role of Antigen Determinants a and B of AB0 Blood Group System in Human Disease Development (Mini Review)

2020 ◽  
Vol 3 (1) ◽  
pp. 39-43
Author(s):  
F.N. Gilmiyarova ◽  
V.I. Kuzmicheva ◽  
N.A. Kolotyeva ◽  
O.Yu. Kuznetsova
Keyword(s):  
Blood Group ◽  
Gastrointestinal Diseases ◽  
Antigenic Determinants ◽  
Epithelial Tissue ◽  
Blood Group System ◽  
Oral Diseases ◽  
Group System ◽  
Pathological Conditions ◽  
H Pylori

AbstractABO blood group system discovery was an important step in development of such areas as transplantation and transfusion medicine. At the same time understanding of fundamental role of antigenic determinants in physiological functions maintenance and pathological conditions development remained unexplained for a long time. Today it is known that A and B antigens are widely represented not only on erythrocytes membrane but also on other cells and tissues: platelets, epithelial tissue, oral and spermal fluids. Earlier authors studied metabolic and coagulation profiles, as well as blood cells composition in clinically healthy individuals on more than 180,000 donations, thus revealing group-specific features for each blood group. The review provides synthesis of association of such pathological conditions as coronary heart disease, thromboembolic complications, tumors of various localizations, inflammatory and destructive oral diseases, psychiatric and some infectious diseases with the presence or absence of antigenic determinants A and B. 0 (I) blood group carriers are more resistant to development of diseases, excepting H. pylori-associated gastrointestinal diseases. Carriers of “antigenic” blood groups A (II), B (III), AB (IV) are more susceptible to infections, cardiovascular diseases, and oncological diseases. The data presented may contribute to a personalized patient approach formation, based on antigen-associated biological variability of various signs in norm and pathology.

scholarly journals The Role of α1-Microglobulin (A1M) in Erythropoiesis and Erythrocyte Homeostasis—Therapeutic Opportunities in Hemolytic Conditions

2020 ◽  
Vol 21 (19) ◽  
pp. 7234 ◽  
Author(s):  
Amanda Kristiansson ◽  
Magnus Gram ◽  
Johan Flygare ◽  
Stefan R. Hansson ◽  
Bo Åkerström ◽  
...  
Keyword(s):  
Intraventricular Hemorrhage ◽  
Macrocytic Anemia ◽  
Blood Transfusions ◽  
Diamond Blackfan Anemia ◽  
Pathological Conditions ◽  
Enzymatic Reduction ◽  
Different Types ◽  
Development Stability

α1-microglobulin (A1M) is a small protein present in vertebrates including humans. It has several physiologically relevant properties, including binding of heme and radicals as well as enzymatic reduction, that are used in the protection of cells and tissue. Research has revealed that A1M can ameliorate heme and ROS-induced injuries in cell cultures, organs, explants and animal models. Recently, it was shown that A1M could reduce hemolysis in vitro, observed with several different types of insults and sources of RBCs. In addition, in a recently published study, it was observed that mice lacking A1M (A1M-KO) developed a macrocytic anemia phenotype. Altogether, this suggests that A1M may have a role in RBC development, stability and turnover. This opens up the possibility of utilizing A1M for therapeutic purposes in pathological conditions involving erythropoietic and hemolytic abnormalities. Here, we provide an overview of A1M and its potential therapeutic effect in the context of the following erythropoietic and hemolytic conditions: Diamond-Blackfan anemia (DBA), 5q-minus myelodysplastic syndrome (5q-MDS), blood transfusions (including storage), intraventricular hemorrhage (IVH), preeclampsia (PE) and atherosclerosis.

scholarly journals Parents’ and Children’s (6–12 Years Old) Physical Activity Association: A Systematic Review from 2001 to 2020

2021 ◽  
Vol 18 (23) ◽  
pp. 12651
Author(s):  
Rui Matos ◽  
Diogo Monteiro ◽  
Nuno Amaro ◽  
Raul Antunes ◽  
Luís Coelho ◽  
...  
Keyword(s):  
Physical Activity ◽  
Systematic Review ◽  
Positive Impact ◽  
Significant Proportion ◽  
Positive Association ◽  
Scientific Papers ◽  
Gender Dyads ◽  
Adults And Children ◽  
Recommended Guidelines

Worldwide, studies reveal that a significant proportion of adults and children do not meet the recommended guidelines for physical activity (PA). Therefore, it is crucial that proxy determinants for child physical activity enhancement could be identified. Parents have been considered to have a key role in child adherence to physical activity. Thus, this systematic review aimed to identify association between parents’ and children’s PA. The search of scientific papers was conducted from 31 October 2020 until 31 January 2021, on the Web of Science, Scopus, Psycinfo, SportDiscus, and Pubmed databases. The PRISMA protocol was used. Findings indicate a consistent association between parents’ and children’s (6–12 years old) PA. Despite the imbalance of the number of assessed fathers and mothers with the latter clearly overrepresented, a trend towards the same gender dyads on PA significant and positive association (father/son, mother/daughter) was evidenced. Results support the relevant importance of parents’ PA as role modeling (either explicitly or implicitly) for children’s PA. Besides, results revealed the importance of promoting PA in family for the enhancement of children’s PA. Moreover, and given the positive impact of exerting PA with the children on children’s PA, parents should spend more time practicing PA with their children, especially on MVPA and meeting the recommended guidelines for PA. Future studies should highlight the role of mediator variables on this interaction process, extending the knowledge on the contribution of other factors to the requested enhancement of children adherence to PA practice.

Potential Uses of Vinegar as a Medicine and Related in vivo Mechanisms

2016 ◽  
Vol 86 (3-4) ◽  
pp. 127-151 ◽  
Author(s):  
Zeshan Ali ◽  
Zhenbin Wang ◽  
Rai Muhammad Amir ◽  
Shoaib Younas ◽  
Asif Wali ◽  
...  
Keyword(s):  
Chemical Structure ◽  
Review Paper ◽  
Heart Diseases ◽  
Folk Medicine ◽  
Active Role ◽  
Current Review ◽  
Different Types ◽  
Positive Effect

While the use of vinegar to fi ght against infections and other crucial conditions dates back to Hippocrates, recent research has found that vinegar consumption has a positive effect on biomarkers for diabetes, cancer, and heart diseases. Different types of vinegar have been used in the world during different time periods. Vinegar is produced by a fermentation process. Foods with a high content of carbohydrates are a good source of vinegar. Review of the results of different studies performed on vinegar components reveals that the daily use of these components has a healthy impact on the physiological and chemical structure of the human body. During the era of Hippocrates, people used vinegar as a medicine to treat wounds, which means that vinegar is one of the ancient foods used as folk medicine. The purpose of the current review paper is to provide a detailed summary of the outcome of previous studies emphasizing the role of vinegar in treatment of different diseases both in acute and chronic conditions, its in vivo mechanism and the active role of different bacteria.

The Diagnosis of Lupus Anticoagulants by the Activated Partial Thromboplastin Time - The Central Role of Phosphatidyl Serine

1984 ◽  
Vol 52 (02) ◽  
pp. 172-175 ◽  
Author(s):  
P R Kelsey ◽  
K J Stevenson ◽  
L Poller
Keyword(s):  
Screening Method ◽  
Coagulation Factors ◽  
Phosphatidyl Serine ◽  
Test System ◽  
Specific Factor ◽  
Marginal Effect ◽  
Constant Composition ◽  
Lupus Anticoagulants ◽  
Different Types

SummaryLiposomes of pure phospholipids were used in a modified APTT test system and the role of phosphatidyl serine (PS) in determining the sensitivity of the test system to the presence of lupus anticoagulants was assessed. Six consecutive patients with lupus anticoagulants and seven haemophiliacs with anticoagulants directed at specific coagulation factors, were studied. Increasing the concentration of phospholipid in the test system markedly reduced the sensitivity to lupus anticoagulants but had marginal effect on the specific factor inhibitors. The same effect was achieved when the content of PS alone was increased in a vehicle liposome of constant composition.The results suggest that the lupus anticoagulants can best be detected by a screening method using an APTT test with a reagent of low PS content. The use of a reagent rich in PS will largely abolish the lupus anticoagulant’s effect on the APTT. An approach using the two different types of reagent may facilitate differentiation of lupus inhibitors from other types of anticoagulant.

Statistical analysis of distribution, dynamics and etiological structure of bovine diseases in Vologda region

2020 ◽  
pp. 3-4
Author(s):  
Oksana B. Badeeva ◽  
Keyword(s):  
Respiratory Diseases ◽  
Birth Rate ◽  
Statistical Data ◽  
Delayed Diagnosis ◽  
Specific Weight ◽  
Gastrointestinal Diseases ◽  
Vologda Region ◽  
High Incidence ◽  
Young Cattle ◽  
High Level

Statistical data of livestock for 30 years is reflected in the article. Author used the materials of the state veterinary reporting. A comparative analysis of the number, incidence and death rate of adult animals and young cattle for two five-year periods (2001-2005 and 2014-2018). the data of the analysis of veterinary statistical reports for 2018 on the specific weight of the large horned cattle and age dynamics of calves in farms of the Vologda region are shown. A significant decrease in livestock of the large horned cattle by 56.3% (from 1990 to 2018) is shown in the analysis of the data. Over the five years 2014-2018, there was a decrease in the number of the large horned cattle by 31.3%, the birth rate of calves - by 26.2%, and the incidence of calves - by 12.3% and the mortality rate decreased by 3.3%. Despite the decline in the number of livestock, in 2018 there is a high incidence of animal diseases (49.6%). The highest incidence rate was observed among calves under 10 days of age 43.3%, 31.7% - from 11 to 30 days, 15.8% - from one to three months, 6.5% - from three to six months and 2.7% - from 6 to 12 months. Of the total number of sick calves in 2018, 63.2% had gastrointestinal diseases, and death for this reason is 49.6% of the total number of victims. Respiratory diseases affect 21.8% of young animals, and death due to respiratory diseases is 18.2%. Analysis of statistical data showed that, despite the complex of veterinary and sanitary measures, the incidence and death of calves remain at a high level. This can be explained by delayed diagnosis and low therapeutic effectiveness in gastrointestinal and respiratory diseases of cattle.

The Role of Evaluative Tools in the Creation of the Memorial Media Portrait of Jacques Chirac (1932—2019)

2020 ◽  
pp. 97-110
Author(s):  
E. N. Mikhailova ◽  
V. A. Telegina
Keyword(s):  
Print Media ◽  
Political Elite ◽  
Systematic Analysis ◽  
Research Material ◽  
Political Orientations ◽  
Different Types ◽  
The Media ◽  
The Creation ◽  
Entire Text

The article is devoted to the study of evaluative tools used in modern French media in order to form the media image of a representative of the political elite. The techniques used in the creation of a memorial media portrait of Jacques Chirac (1932—2019), President of France from 1995 to 2007 are considered. The research material was the most prestigious French print media of various political orientations, published in late September — early October 2019 in connection with the death of the ex-President of the French Republic. The relevance of the research topic is dictated by the close attention of modern linguistics to axiological phenomena, differently presented in different types of discursive practices. The novelty of the study is due to the appeal to the analysis of the complex of evaluation tools used in the French print media when characterizing the former leader of the state during the nation’s farewell period. The estimated potential of the title of the article and its influence on the formation of the estimated vector of the entire text of the publication are shown. A systematic analysis of the assessment expression means, reflected in the memorial media portrait of the politician, is given. The factors that influenced the peculiarities of their use in this type of media portrait are revealed.

Sign in / Sign up

Export Citation Format

Share Document