scholarly journals Prevalence of hypovitaminosis D in severely obese subjects referred to bariatric surgery

2020 ◽  
Vol 53 (1) ◽  
pp. 15-19
Author(s):  
Nataly Azenate Palhares de Oliveira ◽  
Karine Lima Curvello Silva ◽  
Thalane Souza Santos Silva ◽  
Isis Henriques de Almeida Bastos ◽  
Cláudia da Silva Daltro ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Laboratory Data ◽  
Hypovitaminosis D ◽  
Chi Square ◽  
Cross Sectional ◽  
Severely Obese ◽  
Spearman Correlation Test ◽  
Obese Subjects ◽  
The Mean ◽  
Specialized Team

Study Design: Cross-sectional. Objective: Estimating the prevalence of hypovitaminosis D in a group of severely obese subjects referred to bariatric surgery. Methods: This study evaluated severely obese patients aged ≥18 years assisted by a specialized team in bariatric surgery. Clinical, anthropometric, and laboratory data were obtained from patient records. Plasma 25 (OH) D was determined by chemiluminescence and levels ≤ 20 ng/mL was considered as Hypovitaminosis D. The data were analyzed using the Statistical Package for Social Sciences® (SPSS) 20.0. Variables were described using descriptive statistics. For the comparison of the three groups, ANOVA, Kruskal-Wallis, and Pearson's chi-square tests were used. Spearman correlation test was performed to assess correlations between 25(OH)D and the other variables. P-values <0.05 were considered to be significant. Results: The study included 400 individuals, 71% were female with the mean age (SD) and BMI (SD) of 35.6 (9.1) years and 41.4 (5.1) kg/m², respectively. The vitamin D ranged from 4.5 to 62.4 ng/mL and the mean (SD) was 24.7 (7.9) ng/mL. In this sample, 117 (29.3%) individuals had hypovitaminosis D. There was a negative correlation between 25(OH)D and BMI (r= -0.110; p=0.028) and parathormone (r= -0.152; p=0.006) and positive correlation with serum calcium (r= 0.132; p=0.013) and phosphorus (r= 0.116; p=0.027). Conclusion: Severely obese subjects had a high prevalence of hypovitaminosis D even living in a sunny state.

scholarly journals The Association of Hypovitaminosis D with the Metabolic Syndrome Is Independent of the Degree of Obesity

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Inka Miñambres ◽  
Joan Sánchez-Hernández ◽  
Jose Luis Sánchez-Quesada ◽  
Jose Rodríguez ◽  
Alberto de Leiva ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Vitamin D ◽  
Hypovitaminosis D ◽  
Cross Sectional Survey ◽  
Chi Square ◽  
Cross Sectional ◽  
Hydroxyvitamin D ◽  
The Metabolic Syndrome ◽  
Chi Square Test ◽  
The Mean

Background. It remains uncertain whether the metabolic syndrome (MS) or insulin resistance contribute to the association between vitamin D deficiency and obesity. Methods. We conducted a cross-sectional survey of 343 subjects who were overweight or obese. We analyzed anthropometric data and the presence or absence of MS. Additionally, we determined 25-hydroxyvitamin D (25OHD) and insulin concentrations, and the HOMA index was calculated. Chi-square test,Mann-Whitney U test, Student's t-tests,and logistic regression analysis were used. Results. The mean age of the patients was 42±11 years, and 65.9% were women. The mean BMI was 34.7±8.3 kg/m2 and 25(OH)D levels were 53.7±29.8 nmol/L. Forty-six patients (13.4%) had MS. Vitamin D status was associated with the degree of obesity, especially with a BMI > 40 kg/m2. Patients with MS had lower levels of 25(OH)D than patients without (43.3±29.0 versus 55.3±29.6 mmol/L, resp.), and the odds ratio for hypovitaminosis D was 2.7 (confidence interval (CI), 1.14–6.4) (P=.023) for patients with MS versus patients without MS, irrespective of the degree of obesity. Conclusions. Our data confirm the association between vitamin D and MS and suggest that this association is independent of the degree of obesity.

scholarly journals Association Between Vitamin D Status and Physical Function in the Severely Obese

2014 ◽  
Vol 99 (7) ◽  
pp. E1327-E1331 ◽  
Author(s):  
T. Ahern ◽  
A. Khattak ◽  
E. O'Malley ◽  
C. Dunlevy ◽  
M. Kilbane ◽  
...  
Keyword(s):  
Vitamin D ◽  
Physical Function ◽  
Hypovitaminosis D ◽  
Activity Level ◽  
Activity Levels ◽  
Institute Of Medicine ◽  
Vitamin D Status ◽  
Cross Sectional ◽  
Severely Obese ◽  
Obese Subjects

Context: Mortality is 85% higher in severely obese subjects (body mass index [BMI] &gt; 40 kg/m2) than in subjects with a healthy BMI; poor physical function may be contributory. Hypovitaminosis D is common in obese subjects and is associated with physical dysfunction in the elderly. Objective: We determined the relationship between vitamin D status and physical function in severely obese subjects. Design, Setting, and Patients: We conducted a clinic-based, cross-sectional study of severely obese subjects. Participants were stratified into three groups according to the Institute of Medicine (IOM) vitamin D status categorization. Main Outcome Measures: We compared levels of self-reported activity and times taken to walk 500 m and to ascend and descend a 17-cm step 50 times. Results: We recruited 252 subjects (age, 43.7 ± 11.2 y; BMI, 50.7 ± 9.7 kg/m2); 25-hydroxyvitamin D (25OHD) concentrations were less than 30 nmol/L in 109 participants. Participants with a 25OHD &gt; 50 nmol/L, compared to those with a 25OHD &lt; 30 nmol/L, had the highest activity levels (3.1 ± 3.4 h/wk versus 1.5 ± 2.5 h/wk; P = .015) and the shortest 500-m walk times (6.2 ± 1.1 min versus 7.4 ± 1.5 min; P = .003). Serum 25OHD concentrations had a weakly positive association with activity level (r = 0.19; P = .008) and a moderately negative association with 500-m walk time (r = −0.343; P &lt; .001). Conclusions: Vitamin D status had a significant relationship with physical activity and physical function in this cohort of severely obese subjects. Low activity levels are likely to perpetuate the problem of hypovitaminosis D due to less time spent outdoors. Studies exploring the effects of vitamin D supplementation in this population are warranted.

A cross sectional study: The association between sleeping quality and stress among second and third medical students at the University of Jordan

2021 ◽  
pp. 009121742110112
Author(s):  
AA Toubasi ◽  
BR Khraisat ◽  
RB AbuAnzeh ◽  
HM Kalbouneh
Keyword(s):  
Logistic Regression ◽  
Medical Students ◽  
Cross Sectional Study ◽  
Regular Exercise ◽  
Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
The Mean ◽  
University Of Jordan ◽  
The University

Objective Medicine is considered one if not the most stressful educational field. Thus, the aim of this study is to investigate the prevalence of stress and poor sleeping quality among medical students and the association between them. Method This cross-sectional study was conducted at the University of Jordan on second- and third-year medical students. The questionnaire consisted of: 1) Demographics; 2) The assessment tools which were Pittsburgh Quality of Sleep Index (PSQI) and Kessler Psychological Distress Status (K10). Binary logistic regression, chi-square and linear regression were used to investigate the association between PSQI, K10, and their determinants. Results The mean for PSQI score was 6.76 ± 3.32. PSQI scores interpretation revealed that 61.7% of the 282 participants of this study were poor sleepers. Logistic regression results showed that only the category of not napping at all from the napping hours variable was significantly associated with sleeping quality. Furthermore, the mean of K10 scores was 24.5 ± 8.5. K10 scores revealed that 66.3% of the participants were stressed. Logistic regression results showed that gender and regular exercise were significantly associated with psychological distress. Additionally, chi-square test, logistic regression and linear regression showed that PSQI was significantly associated with K10 (P <0.01). Conclusions Stress and poor sleeping quality in medical students at the University of Jordan were highly prevalent and strongly associated. What determined PSQI was daytime napping, and for K10 were regular exercise and gender. Further investigations into stress and sleep quality in the Arabian region are needed.

scholarly journals Systemic disorders and the prognosis of stroke in Congolese patients: a cross-sectional study

2020 ◽  
Vol 54 (4) ◽  
pp. 225-230
Author(s):  
Marc Tshilanda ◽  
Ulrick S. Kanmounye ◽  
Remy Kapongo ◽  
Michel Tshiasuma
Keyword(s):  
Stroke Patient ◽  
Tertiary Hospital ◽  
Cross Sectional Study ◽  
Arterial Hypotension ◽  
Sectional Study ◽  
Stroke Event ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test ◽  
The Mean

Objectives: Stroke is one of the leading causes of death, disability, and dementia in developing countries. Our study aimed to evaluate the systemic disorders associated with mortality in patients admitted within 72 hours of the initial stroke event. Setting: The study took place at a tertiary hospital in Kinshasa. Participants: Patients admitted within 72 hours of the initial stroke event. Interventions: This cross-sectional study consisted of a retrospective review of stroke patient records from January 2016 to December 2018. The Pearson-Chi square test and odds ratios were calculated with a threshold of significance of 0.05. Main outcome measures: Mortality Results: We recruited 114 cases. The mean age was 61.8 ± 2.4 years, and the sex ratio was 1.78 in favor of men. Hypertension (76.3%), dyslipidemia (71.1%), and diabetes mellitus (58.8%) were the most frequent comorbidities. Most patients had hypoxia (85.9%), hypertension (82.4%), hyperglycemia (57.8%), and fever (28.1%). We registered thirty-two deaths (28.1%): 20 (62.5%) from the ischemic strokes, and 12 (37.5%) from hemorrhagic strokes. Systemic disorders with the worst prognosis during were arterial hypotension (OR=3.87, p >0.001), and fever (OR = 1.56, p = 0.047). Conclusion: Arterial hypotension and fever adversely affect stroke patient outcomes, and strokes are responsible for high mortality in Congo

scholarly journals Parental knowledge, attitude and practice on malaria in Mandailing Natal district

2007 ◽  
Vol 47 (4) ◽  
pp. 161
Author(s):  
Syafruddin Haris ◽  
Sri Sofyani ◽  
Bidasari Lubis ◽  
Munar Lubis ◽  
Syahril Pasaribu ◽  
...  
Keyword(s):  
Health Centre ◽  
Parental Knowledge ◽  
Cross Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Factors Affecting ◽  
Attitude And Practice ◽  
The Mean ◽  
Knowledge And Attitude ◽  
Knowledge Attitude And Practice

Background Malaria is still considered to be an important healthproblem in Indonesia. Malaria has been found in islands withdifferent degree of endemicity. Behavior of the community isone of the factors affecting the incidence of malaria in MandailingNatal district.Objective To know the parental knowledge, attitude, and practiceamong parents whose children suffered from malaria or not.Methods A cross sectional study was conducted in six primaryschools and one health centre in October 2004. Subjects wereparents whose children were malaria positive and malaria negativebased on laboratory examination. Sample size was 85 parents foreach group. Selected respondents were interviewed usingstructured questionnaire. Degree of knowledge, attitude, andpractice on malaria were established using scoring system withinthree categories: good, less, and poor. Data were collected andpresented using chi-square and P<0.05 was considered as a levelof significant.Results The mean age of 85 parents whose children were positivemalaria, was 38.47 years (SD 6.67) and the mean age of thosewhose children were negative malaria was 40.41 years (SD 8.05).Parent’s education level was 62.9% primary school and 90% oftheir children were school-aged. There were significant differenceson parental knowledge, attitude and practice in each group(P<0.05). There was also a significant correlation betweenoccupation and knowledge, but not between parental educationlevel and parental age. Parental knowledge and attitude on theincidence of malaria in Mandailing Natal district were good,though their practice were poor.Conclusion There are significant differences on parentalknowledge, attitude and practice, between parents whose childrenwere positive and negative for malaria.

scholarly journals Association of GWAS-Based Candidate Genes with HDL-Cholesterol Levels before and after Bariatric Surgery in the Swedish Obese Subjects Study

2011 ◽  
Vol 96 (6) ◽  
pp. E953-E957 ◽  
Author(s):  
Mark A. Sarzynski ◽  
Peter Jacobson ◽  
Tuomo Rankinen ◽  
Björn Carlsson ◽  
Lars Sjöström ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Weight Loss ◽  
Candidate Genes ◽  
Association Studies ◽  
Statistical Significance ◽  
Genome Wide Association Studies ◽  
Nucleotide Polymorphisms ◽  
Cross Sectional ◽  
Time Points ◽  
Obese Subjects

Context and Objective: The magnitude of weight loss-induced high-density lipoprotein cholesterol (HDL-C) changes may depend on genetic factors. We examined the associations of eight candidate genes, identified by genome-wide association studies, with HDL-C at baseline and 10 yr after bariatric surgery in the Swedish Obese Subjects study. Methods: Single-nucleotide polymorphisms (SNP) (n = 60) in the following gene loci were genotyped: ABCA1, APOA5, CETP, GALNT2, LIPC, LIPG, LPL, and MMAB/MVK. Cross-sectional associations were tested before (n = 1771) and 2 yr (n = 1583) and 10 yr (n = 1196) after surgery. Changes in HDL-C were tested between baseline and yr 2 (n = 1518) and yr 2 and 10 (n = 1149). A multiple testing corrected threshold of P = 0.00125 was used for statistical significance. Results: In adjusted multivariate models, CETP SNP rs3764261 explained from 3.2–4.2% (P &lt; 10−14) of the variation in HDL-C at all three time points, whereas CETP SNP rs9939224 contributed an additional 0.6 and 0.9% at baseline and yr 2, respectively. LIPC SNP rs1077834 showed consistent associations across all time points (R2 = 0.4–1.1%; 3.8 × 10−6 &lt; P &lt; 3 × 10−3), whereas LPL SNP rs6993414 contributed approximately 0.5% (5 × 10−4 &lt; P &lt; 0.0012) at yr 2 and 10. In aggregate, four SNP in three genes explained 4.2, 6.8, and 5.6% of the HDL-C variance at baseline, yr 2, and yr 10, respectively. None of the SNP was significantly associated with weight loss-related changes in HDL-C. Conclusions: SNP in the CETP, LIPC, and LPL loci contribute significantly to plasma HDL-C levels in obese individuals, and the associations persist even after considerable weight loss due to bariatric surgery. However, they are not associated with surgery-induced changes in HDL-C levels.

Effects of Bariatric Surgery on Early Myocardial Alterations in Adult Severely Obese Subjects

Cardiology ◽  
2007 ◽  
Vol 109 (4) ◽  
pp. 241-248 ◽  
Author(s):  
Vitantonio Di Bello ◽  
Ferruccio Santini ◽  
Andrea Di Cori ◽  
Andrea Pucci ◽  
Enrica Talini ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Severely Obese ◽  
Obese Subjects

Abstract 3356: Does Severe Obesity Cause Progressive Impairment of Left Ventricular Systolic Function?

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Theophilus Owan ◽  
Kimberly Morley ◽  
Travis G Ault ◽  
Ronny Jiji ◽  
Nathaniel Hall ◽  
...  
Keyword(s):  
Heart Failure ◽  
Systolic Function ◽  
Left Ventricular Systolic Function ◽  
Left Ventricular ◽  
Entire Group ◽  
Obese Patients ◽  
Cross Sectional ◽  
Increased Risk ◽  
Severely Obese ◽  
The Mean

Background: Obesity is associated with an increased risk of developing heart failure. Based on cross sectional studies, it has been hypothesized that the duration of obesity is the key factor leading to impaired cardiac function. However, longitudinal data to confirm this hypothesis are not available. Methods: We prospectively studied 62 severely obese patients at baseline, 2 and 5 years after randomization to nonsurgical therapy (NonSurg, n = 25) or Rouxen-Y gastric bypass surgery (GBS, n = 37). Echocardiography was used to measure left ventricular (LV) size and ejection fraction (EF). Results: At enrollment, the mean BMI was 46±9 and the mean age was 47±11 years (range 25– 66). GBS subjects lost 96± 26 vs. 6±18 lbs at 2 years and 78±42 vs. 17±42 lbs at 5 years compared to NonSurg (p<0.0001 for both). At baseline LVEF was not different between GBS and nonsurg (67±9 vs. 64±8%) and it did not change at 2 years (64±9 vs. 63±9%) or 5 years (63±9 vs. 63±10%). LV diastolic dimension did not change over time in control (4.3±1.0 vs. 4.2±0.6 vs. 4.5±0.3) or GBS patients (4.4±0.6 vs. 4.3±0.7 vs. 4.4±0.4). Stratifying the entire group by quartiles of age or duration of obesity (quartile 1 avg duration = 16 years, quartile 4 average duration = 56 years), we found no evidence of time-dependent changes in LV size or function. Conclusion: In this, prospective study of severely obese patients we found no evidence of progressive changes in LV size or EF over a period of 5 years. Moreover, we find no relationship between age or duration of obesity and LV size or LVEF. These data argue strongly that other factors such as the development of coronary disease are the most likely causes of heart failure in obese patients.

scholarly journals Kecenderungan dehidrasi pada remaja obesitas

2018 ◽  
Vol 7 (1) ◽  
pp. 43-48
Author(s):  
Deny Yudi Fitranti ◽  
Fillah Fithra Dieny ◽  
Binar Panunggal ◽  
Vintantiana Sukmasari ◽  
Gardinia Nugrahani
Keyword(s):  
Physical Activity ◽  
Risk Factor ◽  
Fluid Intake ◽  
Cross Sectional Study ◽  
Hydration Status ◽  
Obese People ◽  
Chi Square ◽  
Cross Sectional ◽  
Obese Adolescents ◽  
Obese Subjects

Background : The content of water in fat cells in obese people is lower than muscle cells so that obese people are more easily dehydrated.Objective : The purpose of this study is to determine the risk factors of dehydration in adolescents.Methods : This study was a cross sectional study which began with screening of 168 students at SMA N 1 and 2 Semarang and found 63 students fulfilled the inclusion criteria. Subjects were selected by consecutive sampling. The dependent variable of this study is hydration status measured by the urine spesific gravity method. The independent variables consisted of obesity status that determined by the BMI/Age Z-score value, fluid intake was assessed using Semi Quantitative Food Frequency Questionnaire (SQ-FFQ), physical activity was assessed using physical activity questionnaire, whereas knowledge regarding fluid was assessed by questionnaire. Data were analyzed using Chi Square test.Results ; There were 52,4% (n=33) subjects who were obese and only 9,5% (n=6) subjects were well-hydrated. The incidence of dehydration in obese adolescents (63,6%) was higher than non obese adolescents (36,7%). Obese subjects was 1.73 times more dehydrated than non obese subjects. Subject with deficiency of fluid intake was 1,85 times more dehydrated than subject with adequate fluid intake. Knowledge regarding fluid and physical activity was not a risk factor for dehydration in adolescents.Conclusion :Obesity and inadequate fluid intake ia risk factor for dehydration in adolescents

Correlates of Suicidal Ideation and/or Behavior in Bariatric-Surgery-Seeking Individuals With Severe Obesity

Crisis ◽  
2012 ◽  
Vol 33 (3) ◽  
pp. 137-143 ◽  
Author(s):  
E. Y. Chen ◽  
K. C. Fettich ◽  
M. S. McCloskey
Keyword(s):  
Bariatric Surgery ◽  
Suicidal Ideation ◽  
Suicide Attempt ◽  
Severe Obesity ◽  
Suicide Attempts ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Related Stigma ◽  
Severely Obese ◽  
And Control

Background: Approximately 10% of severely obese bariatric-surgery-seeking individuals report a lifetime history of suicide attempts, a higher rate than in the general community. Being overweight is associated with weight-related stigma, making an individual more vulnerable to social isolation, a potential risk factor for suicidal ideation and/or behavior. Aims: In this cross-sectional study of surgery-seeking adults with severe obesity, we examined whether weight-related stigma increases (1) the likelihood of suicidal ideation and/or behavior or (2) the degree of loneliness; and whether hypotheses (1) and (2) are supported (3) if loneliness mediates the effect of weight-related stigma on suicidal ideation and/or behavior. Methods: Online questionnaires were administered to 301 women and 95 men seeking bariatric surgery. Results: Approximately 30.3% reported having at least a passing thought of suicide, and 5.55% a suicide attempt during their lifetime. The suicide attempt rate appears lower than other bariatric surgery samples, but possibly higher than community and other surgery sample rates. For severely obese surgery-seeking women, weight-related stigma was associated with suicidal ideation and/or behavior, though this was not mediated by loneliness. Conclusions: Future studies are needed to model and compare suicidal ideation and/or behavior in bariatric-surgery-seeking individuals and control groups.

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