The Impact of Sentencing Guidelines on State-Level Sanctions: An Analysis Over Time

2004 ◽  
Vol 50 (3) ◽  
pp. 395-411 ◽  
Author(s):  
Sean Nicholson-Crotty
Keyword(s):  
Longitudinal Analysis ◽  
State Level ◽  
Sentencing Guidelines ◽  
Cross Sectional ◽  
Sentencing Decisions ◽  
American States ◽  
The Cross ◽  
Prison Populations ◽  
The Impact ◽  
Over Time

This article argues that the conclusions of previous research on the impact of sentencing guidelines may be misleading due to the cross-sectional methodologies employed in these studies. This study will suggest that a theoretically driven longitudinal analysis of mandatory guidelines offers a more appropriate way to study these policies. Specifically, the author proposes that over time, guidelines that link sentencing decisions to correctional resources help to mitigate prison populations, while those that do not tend to contribute to growth in that area. An analysis of prison populations in the American states between 1975 and 1998 confirms this proposition. The results suggest that mandatory guidelines have increased both commitment and incarceration rates in states where sentencing decisions are not resource driven. Alternatively, when mandatory guidelines are linked to capacity and expenditures, these policies have had either a negative or an insignificant impact on prison populations.

Association between the FINDRISC score and the risk of metabolic syndrome and hepatic steatosis

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
D Godoi Bernardes Da Silva ◽  
R Dias Santos ◽  
M Sommer Bittencourt ◽  
J.A.M Carvalho ◽  
M Franken ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Hepatic Steatosis ◽  
Longitudinal Analysis ◽  
Metabolic Diseases ◽  
Low Cost ◽  
Cross Sectional ◽  
Predictive Values ◽  
Cross Sectional Analysis ◽  
The Cross ◽  
Sectional Analysis

Abstract Introduction The Finnish Diabetes Risk Score (FINDRISC) was developed in Europe to predict type 2 diabetes mellitus (T2DM) risk without need of laboratory tests. Small cross-sectional studies analyzed the association between RF with metabolic syndrome (MS) or hepatic steatosis (HS). Our objective was to test the association of FINDRISC with MS or HS, in a transversal and longitudinal way. Methods In 41,668 individuals (age 41.9±9.7 years; 30.8% women) who underwent health evaluation between 2008 and 2016 in a single centre in Brazil, we tested the transversal association between FINDRISC and MS or HS, in multivariate models. The same analyzes were performed longitudinally in non-diabetic subgroups, followed for 5±3 years, to test the predictive value of FINDRISC and the incidental risk of MS (n=10,075 individuals) or HS (n=7,097 individuals), using logistic regression. Models were adjusted for confounders such as sex, use of medications for dyslipidemia, smoking, and baseline plasma levels of glucose, creatinine and lipids. A receiver operating characteristic (ROC) curve was used to evaluate the discriminative and predictive values of FINDRISC for MS and HS. Results In the cross-sectional analysis, 2,252 (5%) individuals had MS and 14,176 (34%) HS. In the longitudinal analysis, there were 302 cases of incidental MS (2%) and 1,096 cases of HS (15%). FINDRISC was independently associated with MS and HS in the cross-sectional analysis (respectively, OR 1.27, 95% CI: 1.25–1.28, P<0.001; and OR 1.21, 95% CI: 1.20–1.22, P<0.001, per FINDRISC unit) and in longitudinal analysis (respectively, OR of 1.18, 95% CI: 1.15–1.21, P<0.001; and OR of 1.10, 95% CI: 1.08–1.11, P<0.001, per FINDRISC unit). In comparison with individuals with low FINDRISC, those with moderate, high and very high values showed significant and proportional increases of the 12 to 77 fold in the chance of current SM (P<0.001) and 3 to 10 fold in the chance of HS (P<0.001). During follow-up, these increases were 3 to 10 fold in the chance of incidental MS (P<0.001) and 1 to 3 fold in the chance of HS (P<0.001). The AUC from cross-sectional analysis for MS and HS were respectively 0.82 (95% CI 0.81–0.83) and 0.76 (95% CI 0.75–0.76), and in longitudinal analysis 0.73 (95% CI 0.70–0.76) and 0.63 (95% CI 0.61–0.65), respectively. Conclusion FINDRISC was associated with the presence and onset of MS and HS, but it predicted better metabolic syndrome risk than hepatic steatosis. Therefore, this simple, practical and low-cost score can be useful for population screening and identification of subgroups of individuals at higher risk future metabolic diseases. Funding Acknowledgement Type of funding source: None

scholarly journals The Trp64Arg Polymorphism of the β3-Adrenergic Receptor Gene Is Not Associated with Body Weight or Body Mass Index in Japanese: A Longitudinal Analysis

2003 ◽  
Vol 88 (12) ◽  
pp. 5914-5920 ◽  
Author(s):  
Yumi Matsushita ◽  
Tetsuji Yokoyama ◽  
Nobuo Yoshiike ◽  
Yasuhiro Matsumura ◽  
Chigusa Date ◽  
...  
Keyword(s):  
Physical Activity ◽  
Body Mass Index ◽  
Body Weight ◽  
Energy Intake ◽  
Body Mass ◽  
Longitudinal Analysis ◽  
Adrenergic Receptor ◽  
Cross Sectional ◽  
Genotype Frequencies ◽  
The Cross

Abstract The β3-adrenergic receptor (ADRB3) is expressed mainly in visceral adipose tissue and is thought to contribute to lipolysis and the delivery of free fatty acids to the portal vein. Although many studies have examined the relationship between the Trp64Arg mutation of ADRB3 and obesity, the results have been inconsistent. We examined the cross-sectional relationship of ADRB3 variants with indexes of obesity, and their longitudinal changes over 10 yr, in men and women, aged 40–69 yr, who were randomly selected from the Japanese rural population. The study considered both dietary energy intake and physical activity levels. Among the 746 participants, the genotype frequencies of the Trp64Trp, Trp64Arg, and Arg64Arg variants were 483, 224, and 39, respectively. The cross-sectional analysis showed no significant differences in height, weight, body mass index, blood pressure, serum total and high density lipoprotein cholesterols, and hemoglobin A1c among the genotype groups even after adjustments for gender, age, smoking, alcohol drinking, physical activity, and energy intake. No significant differences in the weight changes between the genotype groups were evident in the longitudinal analysis. We conclude that the Trp64Arg mutation of ADRB3 has little or no influence on either body weight or body mass index in the general Japanese population.

Brand awareness: revisiting an old metric for a new world

2017 ◽  
Vol 26 (5) ◽  
pp. 469-476 ◽  
Author(s):  
Jenni Romaniuk ◽  
Samuel Wight ◽  
Margaret Faulkner
Keyword(s):  
Market Share ◽  
Brand Management ◽  
Brand Awareness ◽  
Underlying Structure ◽  
Cross Sectional ◽  
Content Type ◽  
Country Level ◽  
Global Brand ◽  
The Impact ◽  
Over Time

Purpose Brand awareness is a pivotal, but often neglected, aspect of consumer-based brand equity. This paper revisits brand awareness measures in the context of global brand management. Design/methodology/approach Drawing on the method of Laurent et al. (1995), this cross-sectional longitudinal study examines changes in brand awareness over time, with sample sizes of approximately 300 whisky consumers per wave in three countries: United Kingdom, Taiwan and Greece. Findings There is consistency in the underlying structure of awareness scores across countries, and over time, extending the work of Laurent et al. (1995). Results show that a relevant operationalisation of brand awareness needs to account for the history of the brand. Furthermore, the nature of the variation of brand awareness over time interacts with a brand’s market share. Research limitations/implications When modelling the impact of brand awareness researchers need to consider two factors – the brand’s market share and whether a more stable or volatile measure is sought. This avoids mis-specifying the country-level contribution of brand awareness. Practical implications Global brand managers should be wary of adopting a “one size fits all” approach. The choice of brand awareness measure depends on the brand’s market share, and the desire for higher sensitivity or stability. Originality/value The paper provides one of the few multi-country investigations into brand awareness that can help inform global brand management.

Poverty under Planning

2021 ◽  
pp. 254-295
Author(s):  
K. L. Datta
Keyword(s):  
Economic Growth ◽  
Policy Making ◽  
Poverty Reduction ◽  
State Level ◽  
The State ◽  
High Rate ◽  
Methodological Issues ◽  
Poor Households ◽  
The Impact ◽  
Over Time

Describing the manner in which poverty is incorporated as a parameter in planning, this chapter delineates the use of poverty estimates in policy-making, and in tracking progress of development over time and space. It dwells on the methodological issues related to measurement of poverty, and identification of poor households, comprehensively summarizing the debates surrounding it. Viewing the pace of poverty reduction as the ultimate test of planning, it quantifies the level and change in poverty since the 1970s. It analyses the state of poverty at national and state level, and assesses the impact of economic growth and income redistributive measures on poverty reduction. It brings out that the phenomenal decline in poverty in the reforms-era took place exclusively due to increase in income, eventuated by high rate of economic growth. Finally, it states that despite the decline, poverty remains a major concern.

scholarly journals Association between cognitive phenotype in unaffected siblings and prospective 3- and 6-year clinical outcome in their proband affected by psychosis

2020 ◽  
pp. 1-11
Author(s):  
Thijs J. Burger ◽  
Frederike Schirmbeck ◽  
Jentien M. Vermeulen ◽  
Piotr J. Quee ◽  
Mariken B. de Koning ◽  
...  
Keyword(s):  
Repeated Measures ◽  
Psychotic Disorders ◽  
Cognitive Vulnerability ◽  
Familial Risk ◽  
Related Factors ◽  
Cross Sectional ◽  
The Impact ◽  
Cognitive Alterations ◽  
Over Time

Abstract Background Cognitive alterations are a central and heterogeneous trait in psychotic disorders, driven by environmental, familial and illness-related factors. In this study, we aimed to prospectively investigate the impact of high familial risk for cognitive alterations, unconfounded by illness-related factors, on symptomatic outcomes in patients. Methods In total, 629 probands with non-affective psychosis and their sibling not affected by psychosis were assessed at baseline, 3- and 6-year follow-up. Familial cognitive risk was modeled by three cognitive subtypes (‘normal’, ‘mixed’ and ‘impaired’) in the unaffected siblings. Generalized linear mixed models assessed multi-cross-sectional associations between the sibling cognitive subtype and repeated measures of proband symptoms across all assessments. Between-group differences over time were assessed by adding an interaction effect of time and sibling cognitive subtype. Results Probands affected by psychosis with a sibling of the impaired cognitive subtype were less likely to be in symptomatic remission and showed more disorganization across all time points. When assessing differences over time, probands of siblings with the impaired cognitive subtype showed less remission and less improvement of disorganization after 3 and 6 years relative to the other subtypes. They also showed less reduction of positive, negative and excitement symptoms at 6-year follow-up compared to probands with a sibling of the normal cognitive subtype. Conclusions Cross-sibling pathways from higher levels of familial cognitive vulnerability to worse long-term outcomes may be informative in identifying cognition-related environmental and genetic risks that impact psychotic illness heterogeneity over time.

PD-L1 expression of high grade glial tumors at diagnosis and change of expression status at recurrence.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. 2035-2035 ◽  
Author(s):  
Basak Oyan ◽  
Seyma Eren ◽  
Ozlem Sonmez ◽  
Ferda Ozkan ◽  
Kaan Yaltırak ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Immune Checkpoint ◽  
Immune Checkpoint Inhibitors ◽  
Checkpoint Inhibitors ◽  
High Grade ◽  
Cross Sectional ◽  
Glial Tumors ◽  
The Impact ◽  
Expression Status ◽  
Over Time

2035 Background: PD-L1 expression status is the main predictive factor for response to immune checkpoint inhibitors. PD-L1 status may change over time with the impact of therapies. The aim of this study is to determine if PD-L1 expression status changes in recurrent gliomas after chemoradiotherapy. Methods: Thirty eight patients with recurrent high grade gliomas who had surgical excision at least two times were included in this retrospective cross-sectional study. Nine patients were excluded because of the lack of appropriate pathology slides for pathologic evaluation. PD-L1 expression of 29 patients was evaluated by an expert pathologist with immunohistochemical methods. PD-L1 positivity was defined as expression in ≥1% of tumor cells. Change in PD-L1 expression status was defined as an absolute 5% difference between two resections. Results: Of the 29 patients, 15 patients (51.7%) had PD-L1 expression in ≥1% of tumor cells and 7 patients (24.1%) had PD-L1 expression in ≥10% of tumor cells. Tumor PD-L1 expression (defined as expression in ≥1% of tumor cells) was positive in 15 (51.7%) of 29 patients at diagnosis and at the time of recurrence. The PD-L1 status did not change in 17 patients (58.6%). 8 patients had PD-L1 negative tumors both at diagnosis and at recurrence, while 9 patients had PD-L1 positive tumors both at diagnosis and at recurrence. In 6 patients (20.7%) a negative-to-positive switch and in 6 patients (20.7%) a positive to negative switch were seen. Tumor PD-L1 expression increased in 7 of 29 patients (24.1%) and decreased in 9 of 29 patients (31.1%). PD-L1 expression remained stable in 13 of 29 patients (34.4%). The change in PD-L1 status over time was not statistically significant. Conclusions: More than 50% of high grade glial tumors express PD-L1 at diagnosis, so these tumors are good candidates for immune checkpoint inhibitors. The expression status changes in more than 40% of high grade glial tumors at recurrence, so immune responsiveness of glial tumors can be modified by treatments like chemotherapy and radiotherapy.

scholarly journals Analisa Pengaruh Luas Penampang Penghantar dan Cuaca Terhadap Rugi Daya Akibat Korona Pada SUTT 150 kV (Studi Kasus: Gardu Induk Bangkalan – Gardu Induk Sampang)

2019 ◽  
Vol 11 (2) ◽  
pp. 149-159
Author(s):  
Ibnu Hajar ◽  
Tito Dias Fernando
Keyword(s):  
Air Temperature ◽  
Electrical Power ◽  
Cross Sectional Area ◽  
Electricity Sector ◽  
Sectional Area ◽  
Power Losses ◽  
Cross Sectional ◽  
The Cross ◽  
The Impact ◽  
Corona Losses

PT. PLN (PERSERO) as a state-owned company responsible in the electricity sector is required to improve the quality of electricity transmission. In the transmission of electrical power to consumers will be got losses of power. Raising the voltage is an alternative to this problem but it creates new problems because the higher the voltage has increased the corona will occur. The impact of the corona in addition to damaging equipment, noise, and disturbing radio waves, the corona also causes power losses that are proportional to the length of the transmission line. This study uses a quantitative method, by calculating the corona power losses by comparing 4 different cross-sectional areas of the conductor and 4 different air temperatures. The results of this study found that the smaller the cross-sectional area of the conductor the power losses due to corona are smaller, conversely the greater the cross-sectional area the greater the power losses. At the smallest cross-sectional area of 282.6 mm2, the power losses that occurred were 2.013% and at the largest cross-sectional area of 378.7 mm2, the power losses were 5.251%. While the influence of air temperature, the lowest corona losses occur at 29 0C which are 1,223,886 kW and the biggest occur at 24 0C which are 1,373,419 kW, so the higher the air temperature the smaller the corona losses, conversely the lower the air temperature than the higher the corona losses that occur.

scholarly journals Unravelling the impact of COVID-19 on mental health: A scoping review on traumatogenic events using the phases of response to disaster model

2021 ◽  
pp. 218-236
Author(s):  
den Cruyce Nele Van
Keyword(s):  
Mental Health ◽  
Scoping Review ◽  
Disaster Response ◽  
Mental Health Problems ◽  
Economic Status ◽  
Psychological Needs ◽  
Vulnerable Groups ◽  
Cross Sectional ◽  
The Impact ◽  
Over Time

Background: Disease outbreaks such as the COVID-19 pandemic give rise to high levels of psychological distress in people worldwide. Since this is the first pandemic of its kind, the best available evidence is needed on what psychological needs could be expected during and after the pandemic. Objectives: In this scoping review existing research on traumatogenic events is examined in order to identify the potential impact on mental health of the COVID pandemic. The research findings are organized using the the phases of disaster response model. Results: A total of 34 longitudinal studies, 2 studies with multiple waves of data collection and 92 cross-sectional studies met the inclusion criteria. The studies included in this scoping review could be classified as: 87 studies on COVID-19, 2 on SARS, 19 on wars, 19 on terrorist attacks and 1 on a nuclear accident. Results indicate that stress, anxiety, depressive symptoms, insomnia, denial, anger, grief and fear can be anticipated as common reactions. The longer a pandemic continues, the higher the psychological strain is expected to be. Conclusions: The phases of response to disaster model offers a valid frame to unravel the impact of the pandemic on mental health over time. Specific attention must be given to vulnerable groups, whereby specific risk factors include age, gender, pre-existing mental health problems, healthcare profession, migration background, isolation and low socio economic status. However, these may change over time, and a delayed manifestation of psychosocial problems needs to be considered too. Mental health governance is, therefore, warranted throughout and even up to 6 months after the pandemic.

scholarly journals The HIV/STI Epidemic Potential of Dynamic Sexual Networks of Men Who Have Sex With Men in Atlanta and San Francisco

2020 ◽  
Author(s):  
Emeli J. Anderson ◽  
Kevin M. Weiss ◽  
Martina M. Morris ◽  
Travis H. Sanchez ◽  
Pragati Prasad ◽  
...  
Keyword(s):  
San Francisco ◽  
Network Connectivity ◽  
Parameter Estimates ◽  
Sexual Networks ◽  
Age Group ◽  
Exponential Random Graph Models ◽  
Cross Sectional ◽  
The Cross ◽  
Over Time ◽  
Age Category

ABSTRACTBackgroundThe potential speed through which a pathogen may circulate in a network is a function of network connectivity. Network features like degree (number of ongoing partnerships) determine the cross-sectional network connectivity. The overall transmission potential of a pathogen involves connectivity over time, which can be measured using the forward reachable path (FRP). We modeled dynamic sexual networks of MSM in San Francisco and Atlanta to estimate the FRP as a predictor of HIV/STI epidemic potential.MethodsWe used exponential random graph models to obtain parameter estimates for each city’s sexual network and then simulated the complete networks over time. The FRP was estimated in each city overall and stratified by demographics.ResultsThe overall mean and median FRPs were higher in San Francisco than in Atlanta, suggesting a greater epidemic potential for HIV and STIs in San Francisco. At one year, in both cities, the average FRP among casual partnerships was highest in the youngest age group and lowest in the oldest age group, contrasting with the cross-sectional network parameters we estimated, where the youngest age category had the lowest mean degree and the oldest age category had the highest mean degree.ConclusionsThe FRP results correspond to the observed STI epidemics but not HIV epidemics between the cities. In San Francisco, rates of HIV have been declining over the last few years, whereas they have been steady in Atlanta. The FRP by age group resulted in fundamentally different conclusions about connectivity in the network compared with the cross-sectional network measures.

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