scholarly journals Quantifying the potential market for new contraceptive technologies: global projections of 2040 contraceptive needs and preferences

2021 ◽  
Vol 5 ◽  
pp. 152
Author(s):  
Michelle Weinberger ◽  
Meghan Reidy ◽  
William Winfrey
Keyword(s):  
Marital Status ◽  
Sexual Activity ◽  
Contraceptive Use ◽  
Reproductive Age ◽  
Population Projections ◽  
Market Segments ◽  
Fertility Preferences ◽  
Wide Range ◽  
The World ◽  
The Impact

Background: Despite a wide range of contraceptive methods, unmet need persists. New contraceptive technologies (CTs) have the potential to improve uptake and continuation. CT development has a long-time horizon; products will be introduced into markets that look very different than today. Identifying viable investments requires an understanding of these future markets. For this work the 2040 potential contraceptive market is described utilizing seven market segments based on marital status, fertility preferences, and patterns of sexual activity outside of marriage.  Methods: Market size estimates are developed by country for all countries in the world for a current market (2020) and a future market (2040). United Nation’s (UN) population projections of the number of women of reproductive age (WRA) form the basis of this work. WRA are then segmented into market segments based on marital status, fertility intentions, and patterns of sexual activity outside of marriage.  Each segment is further subdivided by contraceptive use versus non-use.  Segmentation draws from UN projections, household surveys, census data, and modeling techniques developed for this work. Results: The largest market increases will be seen in Africa; most notably among the segment of married women wanting no more children. By contrast, Asia will see declines across all three married segments, coupled with increases among sexually active unmarried segments.  Levels of contraceptive use are projected to vary widely by segment, with differential patters across regions. Conclusions: This analysis projects the impact of demographic changes, evolving fertility preferences, shifts in sexual activity outside of marriage and increased utilization of contraceptives in shaping the contraceptive market of 2040. Results show that there is not one global market, but distinct markets that vary in size and shape across the world. This diversity suggests that a range of different new CTs could have potential for uptake.

scholarly journals Hyaluronan and the Fascial Frontier

2021 ◽  
Vol 22 (13) ◽  
pp. 6845
Author(s):  
Rebecca L. Pratt
Keyword(s):  
Nerve Fibers ◽  
The Body ◽  
Water Volume ◽  
Cell Behavior ◽  
Connective Tissues ◽  
Wide Range ◽  
The World ◽  
Extracellular Microenvironment ◽  
The Impact ◽  
The Relationship

The buzz about hyaluronan (HA) is real. Whether found in face cream to increase water volume loss and viscoelasticity or injected into the knee to restore the properties of synovial fluid, the impact of HA can be recognized in many disciplines from dermatology to orthopedics. HA is the most abundant polysaccharide of the extracellular matrix of connective tissues. HA can impact cell behavior in specific ways by binding cellular HA receptors, which can influence signals that facilitate cell survival, proliferation, adhesion, as well as migration. Characteristics of HA, such as its abundance in a variety of tissues and its responsiveness to chemical, mechanical and hormonal modifications, has made HA an attractive molecule for a wide range of applications. Despite being discovered over 80 years ago, its properties within the world of fascia have only recently received attention. Our fascial system penetrates and envelopes all organs, muscles, bones and nerve fibers, providing the body with a functional structure and an environment that enables all bodily systems to operate in an integrated manner. Recognized interactions between cells and their HA-rich extracellular microenvironment support the importance of studying the relationship between HA and the body’s fascial system. From fasciacytes to chronic pain, this review aims to highlight the connections between HA and fascial health.

A New World Economic order formation

2021 ◽  
pp. 932-950
Author(s):  
Vladislav Vyacheslavovich Emelyanov
Keyword(s):  
Oil And Gas ◽  
World Order ◽  
The United States ◽  
New Order ◽  
The West ◽  
Wide Range ◽  
The World ◽  
The Usa ◽  
World Economic Order ◽  
The Impact

Every few decades, the world order changes due to various geopolitical, economic and other circumstances. For example, as a result of globalization, the world order has undergone significant changes in the last forty years. Globalization has led to the destruction of the postwar world order, as well as to world leadership by the United States and the West. However, in recent decades, as a result of globalization, the U.S. and the West began to cede their leadership to developing countries, so there is now a change in the economic structure of relations in the world system. Today the center of economic growth is in the East, namely in Asia. There are no new superpowers in the world at the moment, but the unipolar world will cease to exist due to the weakening of the U. S. leadership, which will lead to a change in the world order. A new leader, which may replace the U. S., will not have as wide range of advantages as the USA has. Most likely, the essence of the new order will be to unite the largest countries and alliances into blocks, for example, the USA together with the Trans-Pacific Partnership, the EU, etc. The article outlines forecasts of GDP growth rates as well as the global energy outlook; analyzes the LNG market as well as the impact of the pandemic on the global oil and gas market; and lists the characteristics of U. S. geopolitics.

Contraception Options in Neurologic Disease

2018 ◽  
Author(s):  
Tessa L. Reisinger ◽  
Amy Robinson Harrington
Keyword(s):  
Chronic Disease ◽  
Contraceptive Use ◽  
Unplanned Pregnancy ◽  
Treatment Options ◽  
Hormonal Contraception ◽  
Neurologic Disease ◽  
Eligibility Criteria ◽  
Increased Risk ◽  
Wide Range ◽  
The Impact

Unplanned pregnancy has particular implications for women with chronic disease, including increased risk of adverse health events during pregnancy and potential impact on disease course or treatment options. While preventing unplanned pregnancy is especially important in this population, both medications and sequelae of chronic disease must be considered in choosing safe and effective contraceptive options. The US Medical Eligibility Criteria for Contraceptive Use were established to provide guidance on contraceptive use for women with various disease conditions; however, specific guidelines for many neurologic conditions are limited. This chapter reviews evidence and recommendations for contraception options in women with a wide range of neurologic conditions. Considerations include interactions with medications, the risk of venous thromboembolism in the setting of reduced mobility, and the impact of hormonal contraception on symptom frequency and disease progression. In many cases, long-acting reversible contraception (LARC) methods offer highly effective, well-tolerated contraception for women with neurologic disease.

scholarly journals Double Burden of Malnutrition among Chinese Women of Reproductive Age and Their Social Determinants

Nutrients ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 3102
Author(s):  
Jingqi Song ◽  
Ji Zhang ◽  
Wafaie Fawzi ◽  
Yangmu Huang
Keyword(s):  
Normal Weight ◽  
Overweight And Obesity ◽  
Living Environment ◽  
Reproductive Age ◽  
Women Of Reproductive Age ◽  
Double Burden ◽  
Community Factors ◽  
Wide Range ◽  
Double Burden Of Malnutrition ◽  
The Impact

This study aimed to examine the impact of a wide range of demographic, socioeconomic, and community factors on the double burden of malnutrition among women of reproductive age using longitudinal data. We used data about 11,348 women of reproductive age who participated in the China Health and Nutrition Survey (CHNS), a longitudinal survey, between 1989 and 2015. Nutritional outcomes were categorized into four groups, namely underweight, normal weight, overweight, and obesity, with normal weight as reference. A multinomial logit model was fitted due to geographic clustering and repeated observations of individuals. The prevalence of underweight decreased over time from 1991 but has tended to rise again since 2004, while the prevalence of overweight/obesity continued to rise between 1991 and 2015. Improved individual factors, socioeconomic status, and community urbanization reduced the risk of underweight but elevated the risk of overweight and obesity. The medium levels, rather than the highest levels, of household income and community urbanization are associated with a higher risk of overweight and obesity. The notable increase in underweight prevalence is a cause for concern to be addressed along with efforts to curb the rising tide of overweight. In order to enhance the nutritional status of women of reproductive age, it is essential to improving the community environment, levels of education, and living environment from a wider context. Long-term and targeted plans are urgently needed for nutrition improvements among the different populations.

scholarly journals Impact of hypocaloric dietary intervention on ovulation in obese women with PCOS

Reproduction ◽  
2017 ◽  
Vol 153 (1) ◽  
pp. R15-R27 ◽  
Author(s):  
Brittany Y Jarrett ◽  
Marla E Lujan
Keyword(s):  
Weight Loss ◽  
Dietary Intervention ◽  
Polycystic Ovary ◽  
Reproductive Function ◽  
Antral Follicle ◽  
Reproductive Age ◽  
Obese Women ◽  
Dietary Interventions ◽  
Wide Range ◽  
The Impact

Polycystic ovary syndrome (PCOS) is a common cause of ovulatory dysfunction affecting women of reproductive age. Obesity and insulin resistance are thought to potentiate disruptions in antral follicle development that result in chronic anovulation, and as such, have become important therapeutic targets of dietary interventions aimed at weight loss. Caloric restriction has been shown to promote sporadic ovulation in obese women with PCOS, but improvements have occurred across a wide range of patients and little has been garnered about the factors that distinguish responders from non-responders. Further, few studies have evaluated the likelihood for modest weight loss to restore normal ovulatory cyclicity in PCOS. Consensus regarding the impact of dietary intervention on ovulation has been limited by variability in the measures used to characterize and report ovulatory status across studies. In response, this review provides an assessment of the evidence surrounding the effectiveness of hypocaloric dietary intervention to normalize ovulatory function in PCOS. The impact of physiological vs methodological factors on the evaluation of ovulatory status is discussed, and recommendations to strengthen future studies in this area are provided. Ultimately, further research is needed to understand the optimal dietary or lifestyle approaches that promote ovulation and sustained improvements in reproductive function in PCOS.

Lilie, Licht und Gottes Weisheit: Philipp Otto Runge und Jacob Böhme

Aries ◽  
2005 ◽  
Vol 5 (2) ◽  
pp. 155-199
Author(s):  
Melanie Öhlenbach
Keyword(s):  
Early Death ◽  
Holy Trinity ◽  
Wide Range ◽  
The World ◽  
Holistic Interpretation ◽  
New Form ◽  
The Impact ◽  
The Trinity ◽  
Life Work

AbstractThe influence of Jacob Böhme on early Romantic art and its philosophy has been largely neglected by modern scholars, even though tracing the impact of Böhme's writing opens a wide range of new interpretations and leads to a deeper understanding. Phillip Otto Runge's life, his theory and works bear testimony to Böhme's importance. The article is divided into five sections: The historical and biographical background (1) forms the basis of describing Runge's demand for a new form of art (“Neue Kunst”) (2): Art is considered as the revelation of God and the artist as its tool, while the artist's imagination creates the insight of God. It is the artists' duty to re-create the diverging harmony of man and cosmos in the sense of an artistic-spiritual revolution. Due to his early death, Runge managed only partly to put his ambitions into practice, notably in the Morning of his Four Times of a Day (Die Vier [Tages-] Zeiten) which was the only one of the four copperplate prints that was finally painted in colours. In its copperplate version (3), Runge uses rich symbolic features that show both his theoretical ambitions and Böhme's influence. The author argues that Runge's work reflects Böhme's ideas of God and the Holy Trinity, angels, the creation of the world, and “Christosophierdquo. In order to understand the full impact of Runge's works, it is also necessary to explain his theory of colours (Farbentheorie) (4). Colours are perceived to be “signature rerum” which indicate the possibility to return to God. Runge's theories of light, the trinity of the primary colours and the harmony of colours as well as their application (transparent or non-transparent) are based on Böhme's spiritual ideas. The final chapter of Runge's life as well as of this article is dedicated to the coloured version of the Morning (Der Kleine Morgen) (5). The author shows how the element of the female figure, which strongly suggests Böhme's idea of “Sophiardquo, is central to the painting. In recognition of all the features previously explained, the author provides a holistic interpretation of Runge's life work that includes and goes beyond previous interpretations.

Introduction

2017 ◽  
Author(s):  
Christine Gledhill ◽  
Julia Knight
Keyword(s):  
Case Studies ◽  
Film History ◽  
Historical Narratives ◽  
Silent Cinema ◽  
Wide Range ◽  
The World ◽  
Recent Developments ◽  
Women's Film ◽  
The Impact ◽  
Different Parts

This book examines film history with the goal of reframing it to accommodate new approaches to women's filmmaking. It brings together a wide range of case studies investigating women's work in cinema across its histories as they play out in different parts of the world from the pioneering days of silent cinema through recent developments in HD transmissions of live opera. It also tackles a range of conceptual and methodological questions about how to research women's film history—how, for example, to reconceptualize film history in order to locate the impact of women in that history. Furthermore, the book looks at the debates over relations among gender, aesthetics, and feminism. In this introduction, a number of interrelated themes and issues that can be grouped into four broad problematics are discussed: evidence and interpretation; feminist expectations of both contemporary and past women's filmmaking; the impact of women's film history on existing historical narratives and theories; and factors that determine the visibility of women's films and build audiences for them.

Comparison of rural versus urban residence for symptoms and quality of life in recurrent ovarian cancer: Baseline analysis of GOG-0259, an NRG Oncology/GOG study.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e18083-e18083 ◽  
Author(s):  
Sarah M. Belcher ◽  
Susan M. Sereika ◽  
Zan M. Dodson ◽  
Meghan K. Mattos ◽  
Teresa Hagan ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Ovarian Cancer ◽  
Marital Status ◽  
Recurrent Ovarian Cancer ◽  
Future Research ◽  
Protective Effects ◽  
Financial Barriers ◽  
Wide Range ◽  
The Impact

e18083 Background: Women with recurrent ovarian cancer (OC) experience a wide range of cancer- and treatment-related symptoms that negatively impact quality of life (QOL). Studies have reported healthcare disparities by geographic residence related to distance, time, and financial barriers to accessing high quality care. However, no studies have evaluated the impact of residence on symptoms and QOL in women with OC. Therefore, our objectives were to evaluate whether geographic residence (urban versus rural) is associated with symptoms and QOL in a sample of women with recurrent OC. Methods: The Center for Health Equity Research and Promotion conceptual framework guided analyses of baseline GOG-0259 data. We mapped zip codes to RUCA commuter codes and compared sociodemographic and clinical variables between rural and urban groups using two-sample t and chi-square tests. We used MANCOVA, adjusted for age and marital status, to test for associations between residence and symptoms (Symptom Representation Questionnaire) and QOL (Functional Assessment of Cancer Therapy-Ovarian). Results: Rural (n = 122, 25%) and urban (n = 374, 75%) women were similar in all sociodemographic and clinical comparisons except for marital status (83% vs. 70% married, p = .003). Women reported moderate symptom severity (M = 5.5, SD = 2.3) and QOL scores similar to other OC studies (M = 108.4, SD = 19.5). In multi-variate analyses, age and marital status were both associated with symptoms; marital status was associated with QOL. Geographical residence was not associated with either symptoms or QOL. Conclusions: Counter to previous research, there were no symptom or QOL disparities based on geographic residence in this sample. Possible explanations to be explored in future research include a) cooperative group selection bias for women with good access to care regardless of geographic residence and b) protective effects of marital status on symptoms and QOL.

scholarly journals The Impact of the Covid 19 Pandemic on the Development of the Fourth Industrial Revolution in Southern Africa

2021 ◽  
Vol 9 (1) ◽  
pp. 56-63
Author(s):  
Elizabeth Ojo-Fafore ◽  
◽  
Clinton Aigbavboa ◽  
Wellington Thwala
Keyword(s):  
Southern Africa ◽  
Human Activities ◽  
Industrial Revolution ◽  
Economic Sector ◽  
African Region ◽  
Fourth Industrial Revolution ◽  
Wide Range ◽  
The World ◽  
The Impact ◽  
Industrial Revolutions

The fourth industrial revolution (4IR) is gradually gaining momentum in a wide range, and as it gathers pace, innovations are becoming faster, more efficient, and widely accessible than before. However, due to the outbreak of Covid 19, the world had seen a shift in the traditional ways in all aspects of human activities, especially in the socio-economic sector. This paper explores the effect of Covid19 on the development of the fourth industrial revolution in the Southern African region and will review the literature on pandemic and its effect on industrial revolutions. It will also review the literature on the fourth industrial revolution, the spread of the Covid 19 pandemic, and its effect on the development of the fourth industrial revolution in Southern Africa.

scholarly journals Scenario of Bangladesh in Various Sectors Due to Covid-19 Pandemic

2021 ◽  
pp. 79-84-79-84
Keyword(s):  
Health Sector ◽  
World Health ◽  
Real Situation ◽  
Significant Damage ◽  
Wide Range ◽  
The World ◽  
Education Service ◽  
Human Need ◽  
Health Organization ◽  
The Impact

Coronavirus disease (COVID-19) has been declared a pandemic by the World Health Organization on the 11th March 2020. COVID-19 has a wide range of effects. Increased Covid-19 infection is a major risk factor due to human unconsciousness and disobedience. The effects are increasing gradually. Therefore, the Bangladesh government has imposed a lockdown, but the outcome is adverse to this lockdown. It has shown us the real situation in our economic, social, education, service, and health sectors. It reveals, in particular, that, as a result of Covid-19, our health sector, which is a basic human need, has entirely broken down, and that, as a result of the epidemic, our educational system has also been impacted. Generally speaking, the education sector will suffer significant damage. Our main purpose in this paper is to show the impact of Covid-19 on different sectors of our country.

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