scholarly journals Correlation between gut pathogens and fecal calprotectin levels in young children with acute diarrhea

2014 ◽  
Vol 54 (4) ◽  
pp. 193 ◽  
Author(s):  
Yanever Angela Lam ◽  
Sarah M. Warouw ◽  
Audrey M.I. Wahani ◽  
Jeanette I.C. Manoppo ◽  
Praevilia Margareth Salendu
Keyword(s):  
Young Children ◽  
Acute Diarrhea ◽  
Neutrophil Migration ◽  
Fecal Calprotectin ◽  
Stool Examination ◽  
Blastocystis Hominis ◽  
Cross Sectional ◽  
Significance Level ◽  
Intestinal Pathogens ◽  
Gut Pathogens

Background In cases of acute diarrhea, it is difficult to distinguishbetween bact erial and non-bacterial causes . Increased fecalcalprotectin (f-CP) level is a marker of neutrophil migration in theintestinal lumen and is associated with intes tinal inflammation.Previous studies reported an increase in f-CP levels in childrenwith acute diarrhea, which is caused by bacteria, but only fewhave studied the relationship between intestinal pathogens withf-CP levels in acute diarrhea.Objective To assess for a correlation between gut pathogens andfecal calprotectin levels in children with acute diarrhea.Methods We conducted a cross-sectional study between Julyto November 2012 on children aged 1-5 ye ars with acutediarrhea, and underwent routine blood tests, stool microscopy,f-CP tests, and stool cultures. We used a simple linear regressionand correlation analysis with a significance level of P< 0.05.Results Forty-two children enrolled in this study. The mean age ofsubjects was 2.27 (SD 134) years. Theirmeanf-CP level was 93.88(SD 14.68) μg/g. On microscopic stool examination, 26 patients( 61.9%) had positive leukocytes, 1 had Ancy lo stoma duodenale, 1had Ascaris lumbricoides, and 2 had Blastocystis hominis. Positivestool cultures were found in 14 children (33.3%) with acutediarrhea. There was a significant positive correlation between gutpathogens and f-CP levels (r=0.605; P< 0.0001).Conclusion In young children with acute diarrhea, the averagef-CP levels are higher in those with positive intestinal pathogens.

scholarly journals Correlation between gut pathogens and fecal calprotectin levels in young children with acute diarrhea

2014 ◽  
Vol 54 (4) ◽  
pp. 193-197 ◽  
Author(s):  
Yanever Angela Lam ◽  
Sarah M. Warouw ◽  
Audrey M.I Wahani ◽  
Jeanette I.C. Manoppo ◽  
Praevilia Margareth Salendu
Keyword(s):  
Young Children ◽  
Acute Diarrhea ◽  
Fecal Calprotectin ◽  
Gut Pathogens

scholarly journals Profil dan Prevalensi Blastocystis hominis di Laboratorium Parasitologi Fakultas Kedokteran Universitas Kristen Indonesia

2021 ◽  
Vol 36 (2) ◽  
pp. 55-62
Author(s):  
Ronny - ◽  
Nadia L. Destifani ◽  
Edho Yuwono ◽  
Forman E. Siagian ◽  
Retno Wahyuningsih
Keyword(s):  
Developed Countries ◽  
Cross Sectional Study ◽  
Emerging Disease ◽  
Stool Examination ◽  
Blastocystis Hominis ◽  
Intestinal Protozoa ◽  
Cross Sectional ◽  
Watery Stool ◽  
Hominis Infection ◽  
Age Range

Abstrak Blastocystis hominis merupakan emerging disease yang terdistribusi luas di dunia, dengan prevalensi 10% di negara maju hingga 60% di negara berkembang. Perannya sebagai mikroorganisme patogen masih kontroversial. Diduga angka kejadian B. hominis lebih banyak didapatkan pada curah hujan yang rendah dan daerah tropis/ sub-tropis. Penelitian dilakukan untuk mengetahui prevalensi, profil B. hominis di Laboratorium Parasitologi Fakultas Kedokteran Universitas Kristen Indonesia, serta hubungan antara angka kejadian infeksi B. hominis dengan curah hujan dan kelembaban pada musim penghujan dan kemarau. Penelitian potong lintang deksriptif berdasarkan data pemeriksaan feses di Laboratorium Parasitologi Fakultas Kedokteran Universitas Kristen Indonesia selama 20 tahun sejak Januari 2000 sampai dengan Desember 2019. Sampel feses diperiksa dari sediaan basah dengan pewarnaan eosin dan lugol, dan hasilnya dilaporkan dengan sistem skoring semi kuantitatif. Data curah hujan dan kelembaban didapatkan dari Badan Meteorologi Klimatologi dan Geofisika Stasiun Meteorologi Kemayoran Jakarta.Didapatkan 3270 sampel, dengan hasil sampel positif B. hominissebanyak 440 sampel (14%), Prevalensi pada perempuan lebih tinggi dibandingkan laki-laki dan terbanyak pada kelompok usia 21-60 tahun (67,4%). Persentase tertinggi ditemukan pada feses dengan konsistensi cair. Tidak ditemukan hubungan antara prevalensi infeksi B. hominis dengan curah hujan (P=0,285) dan kelembaban (P=0,204).   Kata kunci: prevalensi, konsistensi, curah hujan, kelembaban, musim   Profile and Prevalence of Blastocystis hominis at Parasitology Laboratory, Medical Faculty Universitas Kristen Indonesia   Abstract Blastocystis hominis is an emerging disease that is widely distributed in the world, with a prevalence of 10% in developed countries to 60% in developing countries. Its role as a pathogen is still controversial. It is suspected that the incidence of B. hominis is mostly found in low rainfall and tropical/ sub-tropical areas. The study was conducted to determine the prevalence and profile of B. hominis in the Laboratory of Parasitology, Faculty of Medicine, Universitas Kristen Indonesia.and the relationship between incidence of B. hominisinfection with rainfall and humidity in the rainy and dry seasons.This descriptive cross-sectional study was based on fecal examination data at the FK UKI Parasitology Laboratory for 20 years. from January 2000 to December 2019. Stool examination was carried out by making eosin and lugol wet preparations to examine intestinal protozoa, and the results were reported using a semi-quantitative scoring system.Rainfall and humidity data are obtained from the Meteorology, Climatology and Geophysics Agency of the Stasiun MeteorologiKemayoran, Jakarta. As many as3270 samples were obtained, feses with B. hominis positive results was 440 samples (14%). Based on gender, 53.1% of B. hominisinfected were women and most patients were found in the age range from 21 to 60 years (67.4%). The highest percentage was found in watery stool. There was no statistically significant between the prevalence of B. hominis infection with rainfall (p= 0.285) and humidity (p= 0.204).   Key words: prevalence, consistency, rainfall, humidity, season

scholarly journals Television watching time and cognitive development in young children

2012 ◽  
Vol 52 (1) ◽  
pp. 32
Author(s):  
Anak Agung Ayu Windi Antari ◽  
I Gusti Ayu Trisna Windiani ◽  
Djauhar Ismail
Keyword(s):  
Cognitive Development ◽  
Young Children ◽  
Television Viewing ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Television Watching ◽  
Significance Level ◽  
The Mean ◽  
Post Hoc

Background Television viewing for children is prevalent. Therehave been few Indonesian studies on the association betweenduration of television watching and cognitive development inyoung children.Objective To assess cognitive development in young children whowatched < 1 hour, 1-2 hours, or > 2 hours of television daily.Methods We conducted a cross-sectional study at 6 prekindergartensin Denpasar, Bah. We included 135 subjects in thisstudy. Cognitive development was measured by the Mullen ScalesofEarly Learning (MSEL). Data was analyzed by one-way analysisof variance (ANOVA) test, post-hoc test, and univariate analysisof covariance (ANCOVA) with significance level of P < 0.05.Results There were significant differences among compositestandard score in children who watched television < 1 hour, 1-2hours, and> 2 hours per day (P=0.035). The mean compositestandard score in children who watched television 1-2 hours dailywas 6.087 points higher than in those who watched television< 1 hour daily (P=0.013, 95%CI 1.29 to 10.88) and 4.213points higher than in those who watched television > 2 hoursdaily (P=0.045, 95%CI 1.08 to 8.51). There was an associationbetween television watching time and cognitive development(P=0.001).Conclusion Television watching time was statistically associatedwith cognitive development in young children, where thoseviewing television 1-2 hours daily scoring significantly higher thanthose viewing < 1 hour and > 2 hours daily. [Paediatr lndones.2012;52:32-7].

scholarly journals Zinc therapy for different causes of diarrhea

2013 ◽  
Vol 53 (6) ◽  
pp. 334
Author(s):  
Hafaz Zakky Abdillah ◽  
Supriatmo Supriatmo ◽  
Melda Deliana ◽  
Selvi Nafianti ◽  
Atan Baas Sinuhaji
Keyword(s):  
Disease Severity ◽  
Acute Diarrhea ◽  
Cross Sectional Study ◽  
T Test ◽  
Stool Examination ◽  
Bacterial Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Past ◽  
Bacterial Diarrhea

Background The incidence of diarrhea in Indonesia has declinedin the past five years. In spite of the increasing number of studieson the treatment for acute diarrhea, especially the use of zinc,it is not known if bacterial vs. non-bacterial etiology makes adifference in the reduction of severity of acute diarrhea in childrenon zinc therapy.Objective To assess the effect of zinc therapy in reducing theseverity of acute bacterial and non-bacterial diarrhea.Methods We performed a cross-sectional study in the SecanggangDistrict, Lan gkat Regen cy of North Sumat era, from Augustto November 2009 in children aged 2 months to 14 years .Microscopic stool examination s were undertaken to separatesubjects into the acute bacterial or non-bacterial diarrhea groups.Both groups received 10 mg/day ofzinc sulphate for subjects aged<6 months or 20 mg/day for those aged 2:6 months for 10 days.Measurement of disease severity was based on the frequency ofdiarrhea (times/day) and the duration of diarrhea (hours) afterinitial drug consumption . We performed indepen dent T test forstatistical an alysis.Results Sixty-two children participated in this study, with 31children in the acute bacterial group, and the remainder in thenon-bacterial group. There were no significant differences betweenthe two gro ups in frequency of diarrhea (2 .61 vs 2.70 times/day,respectively, P=0.27) or in duration of diarrhea (63.39 vs 66.68hours, respectively, P= 0.06) .Conclusion Zinc is not more effective in reducing the severityof acute bacterial diarrhea compared to non-bacterial diarrhea inchildren.

scholarly journals GAMBARAN GEJALA DAN TANDA KLINIS DIARE AKUT PADA ANAK KARENA BLASTOCYSTIS HOMINIS

e-CliniC ◽  
2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Mona C. U. Aman ◽  
Jeanette I. Ch. Manoppo ◽  
Rocky Wilar
Keyword(s):  
Acute Diarrhea ◽  
Clinical Symptoms ◽  
Clinical Signs ◽  
Vital Signs ◽  
Age Group ◽  
Blastocystis Hominis ◽  
Design Data ◽  
Cross Sectional ◽  
Hominis Infection ◽  
Group 1

Abstract: This study aimed to obtain the description of symptoms and clinical signs of acute diarrhea in children because of Blastocystis hominis. This was a descriptive study with a cross-sectional retrospective design. Data were obtained from medical records of pediatric patients diagnosed as acute diarrhea due to Blastocystis hominis infection from January 2010 - September 2014 in Gastroenterology Children ward Prof. Dr. R. D. Kandou Hospital Manado. Data were clinical symptoms, vital signs, and nutritional status. There were 31 samples, 24 (77.4 %) males and 7 (22.6 %) females. Most children who suffered were in the age group 1-3 years as many as 18 (58.1 %) children. The most frequent clinical symptoms were diarrhea 29 (93.5 %) patients, fever 27 (87.1 %) patients, and vomiting 21 (67.7 %) patients. Conclusion: Children of acute diarrhea due to Blastocystishominis infection were most frequent in the age group 1-3 years, males, with clinical symptoms acute diarrhea, fever, and vomiting.Keywords: acute diarrhea, blastocystishominis, childrenAbstrak: Penelitian ini bertujuan untuk mengetahui gambaran gejala dan tanda klinis diare akut pada anak karena Blastocystis hominis. Penelitian ini bersifat deskriptif retrospektif dengan pendekatan potong lintang. Data diperoleh dari rekam medik pasien anak dengan diagnosis diare akut karena infeksi Blastocystis hominis periode Januari 2010-September 2014 di Bangsal Gastroenterologi Anak Rumah Sakit Prof. Dr. R. D. Kandou Manado. Data berisi gejala klinis dan tanda vital serta status gizi. Sampel penelitian berjumlah 31 anak, 24 (77,4%) anak laki-laki dan 7 (22,6%) anak perempuan. Umur yang paling banyak menderita diare akut karena Blastocystis hominis yaitu 1 – 3 tahun sebanyak 18 (58,1%) anak. Gejala klinis yang paling sering muncul yaitu buang air besar cair sebanyak 29 (93,5%) pasien, demam sebanyak 27 (87,1%) pasien,dan muntah sebanyak 21 (67,7%) pasien. Tanda vital menunjukkan nilai normal. Simpulan: Anak diare akut karena infeksi Blastocystis hominis terbanyak pada kelompok umur 1 – 3 tahun. Anak diare akut karena infeksi Blastocystis hominis terbanyak pada jenis kelamin laki-laki. Gejala klinis yang ditemukan pada pasien diare akut karena infeksi Blastocystis hominis ialah buang air besar cair, demam dan muntah dengan tanda vital normal.Kata kunci: anak, blastocystishominis,diare, akut

scholarly journals Pengetahuan Berhubungan dengan Sikap Ibu dalam Kemampuan Menstimulasi Pertumbuhan dan Perkembangan Anak Balita dengan Gizi Kurang

2016 ◽  
Vol 4 (2) ◽  
pp. 63
Author(s):  
Sulistyawati Sulistyawati ◽  
M Ros Mistyca
Keyword(s):  
Young Children ◽  
Growth And Development ◽  
Rank Correlation ◽  
Sampling Technique ◽  
Health Centers ◽  
Cognitive Domain ◽  
Bivariate Analysis ◽  
Cross Sectional ◽  
Significance Level ◽  
Work Area

<p>Nutrition is an important factor in determining the level of health. The state of malnutrition in children results in impaired growth and development of children. Knowledge or cognitive domain is very important for the formation of maternal attitudes and actions in stimulating the growth and development of children.<br />Children who are directed stimulation will grow faster than children who did not receive stimulation. The purpose of study is to know the relationship of knowledge with mother attitude in the ability to stimulating growth and development of young children with less nutrition in Banaran village work area Galur II Health Centers Kulon Progo Yogyakarta. This type of research is an analytic survey, with the cross sectional approach. The sampling technique is purposive sampling, with 43 respondents. Bivariate analysis used Spearman Rank correlation. The results showed the knowledge of mothers with 25.6% in good category category, 67.4% in enough category, and 7,0% in less category. While the mother’s attitude showed 18.6% in good categories, and 81.4% in enough category. The results of the statistical test showed r=0.467 with a significance level of correlation coefficient 0.002. Conclusion, the research indicated that significant relationship between knowledge with mother attitude in the ability to stimulating growth and development of young children with less nutrition in Banaran village work area Galur II Health Centers Kulon Progo Yogyakarta.</p>

Maternal Knowledge Factor, Maternal Age and Maternal Parity Associated with Genesis of Normal Delivery at Palembang Hospital of Bari Year 2017

2018 ◽  
Vol 1 (1) ◽  
pp. 43-50
Author(s):  
Juliana Widyastuti Wahyuningsih
Keyword(s):  
Maternal Age ◽  
World Health ◽  
Survey Method ◽  
P Value ◽  
Maternal Knowledge ◽  
Cross Sectional ◽  
Normal Delivery ◽  
Significance Level ◽  
Birth Canal ◽  
Maternal Parity

Childbirthis a processLabor of opening and depleting the cervix and the fetus down into the birth canal. Birth is a process in which the fetus and amniotic are pushed out through the birth canal. (Sarwono, 2008). According to the World Health Organization (WHO) estimates more than 585,000 mothers annually die during pregnancy or childbirth. Indonesia Health Demographic Survey (SDKI) Survey in 2012, Maternal Mortality Rate in Indonesia is still high at 359 per 100,000 live births. The purpose of this study is the knowledge of maternal knowledge, maternal age, and maternal parity associated with normal birth events at Palembang Bari Hospital 2017. This study used analytical survey method with cross sectional approach. The population in this study were all maternal mothers at the Palembang Bari Hospital in 2017. Sampling in the study was conducted non-randomly with the technique of "Accidental Sampling". Data analysis was done univariat and bivariate with Chi-Square statistical test with significance level α = 0,05. The result of this research shows that there is correlation between mother's knowledge with normal delivery incidence with p value 0,001, there is correlation between mother age with normal delivery incidence with p value 0,009, there is relation between mother parity with normal delivery incidence with p value 0,001. From result of this research hopes healthcare workers can improve normal delivery care services and more often to carry out maternal safety counseling.

Burden of Care Among Mothers Having Children with Congenital Heart Diseases

2020 ◽  
Vol 40 (2) ◽  
pp. 72-77
Author(s):  
Nita Sharma ◽  
Pratima Sharma ◽  
Tulashi Adhikari Mishra
Keyword(s):  
Heart Disease ◽  
Congenital Heart ◽  
Heart Diseases ◽  
Sampling Technique ◽  
Structured Interview ◽  
Health Condition ◽  
P Value ◽  
Burden Of Care ◽  
Cross Sectional ◽  
Significance Level

Introduction: Congenital Heart Disease (CHD) is a problem with structure and function of the heart that is present at birth.  Children with CHD require special care, treatment and follow up for a number of common conditions which may be quite straining to the care givers. The objective of the study was to find out the burden of care among mothers having children with CHD. Methods: This descriptive cross-sectional study was carried out in a cardiac centre of Nepal. A total of 95 mothers having children with CHD attending outpatient department of our institute were selected as the sample for the study using non-probability purposive sampling technique. A semi structured interview questionnaire consisting of the Modified Caregiver Strain Index was used to assess the burden of care among mothers having children with CHD. Frequency and percent were used to describe the variables and chi- square test at 0.05 significance level was used to analyse associations. Results: Most (77.9%) of the mothers were regularly strained to find that their children’s health condition was deteriorating due to CHD. Nearly half (44.2%) of the mothers always had financial constrain while giving care to the child, nearly half (40%) of the mothers had done emotional adjustments to take care of their children with CHD, another two-fifths (28.4%) of the mothers sometimes had disturbed sleep and almost half (46.3%) of the mothers were always upset due to some behaviour of their child with CHD. Half (50.5%) of the mothers had high level of burden of care. Statistically significant association were found between age of the mother and level of burden of care (p value = 0.05). Similarly, the type of family (p value = 0.005), age of the children (p value = 0.000) and type of CHD (p value = 0.002) were significantly associated with the level of burden of care among the mothers. Conclusion: The study concluded that mothers tend to feel less burden of care as the child grows older, mothers having children with cyanotic heart disease tend to experience more burden of care. Mothers of less than thirty years of age and living in a joint family also experience more burden of care.  

HUBUNGAN AKTIVITAS FISIK DENGAN FUNGSI KOGNITIF LANSIA DI PANTI WREDHA YAYASAN SOSIAL SALIB PUTIH SALATIGA

2019 ◽  
pp. 137-143
Author(s):  
Dennys Christovel Dese ◽  
Cahyo Wibowo
Keyword(s):  
Physical Activity ◽  
Cognitive Function ◽  
The Elderly ◽  
Moderate Physical Activity ◽  
Cross Sectional ◽  
Significance Level ◽  
The Social ◽  
Normal Cognitive Function ◽  
Intellectual Capacity ◽  
Independent Variable

Peningkatan jumlah lansia setiap tahunnya harus dijadikan perhatian, akibat adanya peningkatan jumlah lansia masalah yang dihadapi akan menjadi semakin kompleks, salah satunya adalah masalah yang berkaitan dengan gejala penuaan. Menurunnya kapasitas intelektual berhubungan erat dengan fungsi kognitif pada lansia. Aktivitas fisik diidentifikasi sebagai salah satu faktor yang mempengaruhi fungsi kognitif. Aktivitas fisik bermanfaat untuk lansia sebagai pencegahan dan demensia. Penelitian ini merupakan penelitian analitik observasional dengan menggunakan pendekatan cross sectional. Penelitian dilakukan di yayasan sosial Panti Wredha Salib Putih Salatiga pada bulan Juni 2018. Populasi dalam penelitian ini adalah lansia yang berumur ?60 tahun. Subjek pada penelitian ini berjumlah 16 responden. Variabel independen dalam penelitian ini adalah aktivitas fisik yang dinilai dengan menggunakan instrument GPAQ. Sedangkan variabel dependen dalam penelitian ini adalah fungsi kognitif yang dinilai dengan instrument MMSE. Terdapat 4 orang (25%) yang masuk dalam kategori fungsi kognitif normal dengan kategori aktifitas fisik sedang 1 orang dan aktifitas berat 3 orang, kemudian yang termasuk dalam kategori gangguan fungsi kognitif ringan sebanyak 11 orang (68,75%), dengan kategori aktifitas fisik sedang 8 orang dan aktifitas ringan 3 orang. Sedangkan yang termasuk dalam kategori gangguan fungsi kognitif berat, terdapat 1 orang (6,25%) dengan kategori aktifitasnya ringan. Taraf signifikansi antar variabel tingkat aktifitas fisik dan fungsi kognitif pada lansia adalah p=0.007 atau p<0,05, sehingga dapat disimpulkan ada  hubungan antara tingkat aktifitas fisik dengan fungsi kognitif pada lansia.   Increasing the number of elderly people every year should be a concern, due to an increase in the number of elderly problems faced will become increasingly complex, one of which is a problem related to the symptoms of aging. Decreased intellectual capacity is closely related to cognitive function in the elderly. Physical activity is identified as one of the factors that influence cognitive function. Physical activity is beneficial for the elderly as prevention and dementia. This study was an observational analytic study using a cross sectional approach. The study was conducted at the social foundation nursing home in the white cross in June 2018. The population in this study was elderly aged ≥60 years. The subjects in this study were 16 respondents. The independent variable in this study is physical activity that is assessed using the GPAQ instrument. While the dependent variable in this study was cognitive function which was assessed by the MMSE instrument. There are 4 people (25%) who fall into the category of normal cognitive function with moderate physical activity categories 1 person and heavy activities 3 people, then those included in the category of mild cognitive function disorders are 11 people (68.75%), with the category of physical activity being 8 people and 3 light activities. While those included in the category of severe cognitive function disorders, there is 1 person (6.25%) with a mild activity category. The significance level between the level of physical activity and cognitive function in the elderly is p = 0.007 or p <0.05, so it can be concluded that there is a relationship between the level of physical activity and cognitive function in the elderly.

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