scholarly journals Selenium and manganese in depression – preclinical and clinical studies

2017 ◽  
Vol 30 (3) ◽  
pp. 151-155
Author(s):  
Karolina Slawinska ◽  
Gabriela Bielecka ◽  
Karol Iwaniak ◽  
Sylwia Wosko ◽  
Ewa Poleszak

AbstractAccording to the World Health Organization estimates, approximately 10% of the world’s population is affected by depressive disorders. Furthermore, even in high-income countries, many people with depression are not treated, which can lead to serious health consequences and a global economic loss. Unfortunately, the current pharmacotherapy of depressive disorders is characterized by unsatisfactory efficacy and the therapeutic effect is accompanied by many side effects. For this reason, there is still ongoing worldwide research to find new antidepressant therapies. In recent years, many data have been shown that essential elements demonstrate the antidepressant action and increase the effect of antidepressants. In this paper we present the results from the preclinical and clinical studies published over the years which show the involvement of selenium and manganese in depressive disorders. In this article, the relationship between the amount of these microelements in a diet and depression is reviewed and what's more, the association among these elements in different biomaterial and their relations to depressive symptoms is presented. Additionally, we discuss the possible influence of selenium and manganese on modulating neurotransmitter system involved in depression.

2021 ◽  
pp. 0261927X2110263
Author(s):  
David M. Markowitz

How do COVID-19 experts psychologically manage the pandemic and its effects? Using a full year of press briefings (January 2020–January 2021) from the World Health Organization ( N = 126), this paper evaluated the relationship between communication patterns and COVID-19 cases and deaths. The data suggest as COVID-19 cases and deaths increased, health experts tended to think about the virus in a more formal and analytic manner. Experts also communicated with fewer cognitive processing terms, which typically indicate people “working through” a crisis. This report offers a lens into the internal states of COVID-19 experts and their organization as they gradually learned about the virus and its daily impact.


2021 ◽  
Vol 5 ◽  
pp. 239784732098525
Author(s):  
Keneth Iceland Kasozi ◽  
Eric Oloya Otim ◽  
Herbert Izo Ninsiima ◽  
Gerald Zirintunda ◽  
Andrew Tamale ◽  
...  

Background: Environmental contamination with elevated levels of copper (Cu), cobalt (Co), iron (Fe), zinc (Zn), lead (Pb), chromium (Cr6+), cadmium (Cd), and nickel (Ni)—all states of which are found in Uganda—raises health risk to the public. Pb, Cr6+, Cd, and Ni for instance are generally considered nonessential to cellular functions, notwithstanding the importance of the oxidative state of the metals in bioavailability. As such, we aimed in this study (i) to evaluate heavy metal concentrations in four vegetables from a typical open-air market in Uganda, (ii) to assess the safety of consuming these vegetables against the World Health Organization (WHO) recommended limits of heavy metals consumption, and (iii) to formulate a model of estimated daily intake (EDI) among consumers in the country. Methods: This was a cross-sectional study conducted in five georeferenced markets of Bushenyi district in January 2020. Amaranthus, cabbages, scarlet eggplants, and tomatoes were collected from open markets, processed, and analyzed by atomic absorption spectrometry. Modeled EDI, principal component (PCA) and cluster analysis (CA) were conducted to identify relationships in the samples. Results: The levels of essential elements in the four vegetables were found to fall from Co > Cu > Fe > Zn. Those of non-essential metals were significantly higher and followed the pattern Cd > Cr > Pb > Ni. The highest EDI values were those of Cu in scarlet eggplants, Zn in amaranthus, Fe in amaranthus, Co in amaranthus, Pb in cabbages, total Cr in scarlet eggplant, Cd in cabbages and tomatoes, and Ni in cabbages. In comparison to international limits, EDIs for Zn, Cu, Co and Fe were low while Ni in cabbages were high. PCA showed high variations in scarlet eggplant and amaranthus. The study vegetables were found to be related with each other, not according to the location of the markets from where they were obtained, but according to their species by CA. Conclusion: The presence of non-essential elements above WHO limits raises policy challenges for the consumption and marketing of vegetables in the study area. Furthermore, low EDIs of essential elements in the vegetables create demand for nutritious foods to promote healthy communities.


2016 ◽  
Vol 40 (2) ◽  
pp. 152-155 ◽  
Author(s):  
TE Shishniashvili ◽  
NN Suladze ◽  
VV Margvelashvili

Objectives: To study the influence of environmental pollution on the mineralization of dental hard tissues by using biosubstrates: teeth and hair. :Study design: At the first stage epidemiological survey was conducted in polluted and less polluted areas of Tbilisi (Georgia). We studied 525 children aged 3 and 4 years. Caries prevalence and intensity was defined by the methodology of World Health Organization. At the second stage the chemical elements content was studied in hair and teeth hard tissues of 24 children by X - ray fluorescent spectroscopy method. Results: The prevalence of dental caries in the polluted region was 46%, caries intensity − 1.92 (± 2.842). In the less polluted region prevalence was 37%, caries intensity − 1.47 (± 2.571). These data are statistically reliable (p < 0.05). The study of hair and tooth tissues showed that the toxic elements (Pb, Hg, Sn, Ti) content in these tissues was higher in environmentally unfavorable than in favorable conditions. Conclusion: Hair and dental tissues can be used as indicators of environmental pollution. Our survey showed that toxic elements content in dental hard tissues was higher and the level of essential elements was less in polluted than in less polluted areas of Tbilisi.


2021 ◽  
pp. 104365962110469
Author(s):  
Giorgia Rudes ◽  
Claudia Fantuzzi

Introduction: The World Health Organization states that suicide is the second leading cause of death among youngs, and racism has been proven to have detrimental effects on both physical and mental health. These two plagues represent a public health priority, especially for susceptible minorities. Method: This systematic review analyzed 23 studies from multiple database searches, to understand the relationship between racism and suicidality in young minority groups. Results: The review demonstrated the correlation between racism and suicidality with the consequent development of mental disorders. There is strong evidence that the main suicide risk factor is acculturation, interpreted as the assimilation of the dominant culture with the loss of values from one’s cultural background. Discussion: Health care professionals should not underestimate the risk of suicidality associated with racism. Prevention is crucial and it should be implemented from a young age, in schools, through a joint intervention with children and their families, aiming toward integration without acculturation.


2021 ◽  
Vol 4 (1) ◽  
pp. 01-17
Author(s):  
Ahmed Fahim Elgendi ◽  
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...  

Currently, the world encounters the outbreak of an unprecedented epidemic named novel coronavirus COVID -19. World Health Organization (WHO) advises maintaining social distancing, preserving personal hygiene, and staying informed with the latest guidelines. WHO also reports the patients with robust immunity can combat the virus. However, the workers in the construction industry work and live in a crowded and non-hygiene environment. Moreover, they are characterized by illiteracy, a dearth of awareness, and chronic health problems that prove weak immunity. Therefore, this study aims to find the relationship between the virus and the prevailing conditions and the environment of the construction industry, under focus, and study so that the construction industry is not a vulnerability gap that may exacerbate the crisis. An extensive literature exploration for the latest research deals with coronavirus, the construction industry ergonomics, and its relevant diseases. This study makes robust alerts to motivate the governments, organizations, and individuals to collaborate to find solutions to close the gap between the current situation in the construction of ergonomics and the required precaution to avoid the outbreak of the virus. This study makes a crucial and novel contribution by paving the way for providing solutions to save humanity worldwide. The management system should review the conventional risk assessment procedures, and developed criteria must be introduced and become an everyday practice of all construction projects. This will help identify the gaps within the safety procedures associated with the COVID – 19 protection aspects. This article also introduces a framework in this regard.


2021 ◽  
Vol 43 (4) ◽  
pp. 336-353
Author(s):  
Kaitlyn M. Forristal ◽  
John M. Laux ◽  
Madeline Clark ◽  
Jennifer L. Reynolds ◽  
Taylor M. Nelson

The Centers for Disease Control and Prevention and the World Health Organization have documented an increase in fat people in recent decades, which is being met with a backlash of anti-fat biases, or fatmisia. Fatmisia is prevalent in most aspects of society, especially among fat people who have internalized fatmisia. Utilizing a diagnostic questionnaire in combination with the Fat Phobia Scale–Short Form and the Weight Bias Internalization Scale, this study explored the relationship between client body size, the presence of a major depressive disorder (MDD) diagnosis, and if applicable, the severity of MDD symptoms assigned by counselor trainees (N = 113). Results were analyzed using one-way analysis of variance and covariance. This sample (N = 113) significantly differed in diagnoses assigned to obese clients by assigning more severe MDD. Study limitations and implications are discussed.


Author(s):  
Kumar Abhishek ◽  
M. P Singh ◽  
Md. Sadik Hussain

<p>Tuberculosis (TB) has been one of the top ten causes of death in the world. As per the World Health Organization (WHO) around 1.8 million people have died due to tuberculosis in 2015. This paper aims to investigate the spatial and temporal variations in TB incident in South Asia (India, Bangladesh, Pakistan, Maldives, Nepal, and Sri-Lanka). Asia had been counted for the largest number of new TB cases in 2015. The paper underlines and relates the relationship between various features like gender, age, location, occurrence, and mortality due to TB in these countries for the period 1993-2012.</p>


Author(s):  
Ayu Kurniati ◽  
Enny Fitriahadi

IN 2013, the World Health Organization, released data in the form of Maternal Mortality Rate (MMR) worldwide, and the number reached 289,000 per 100, 000 live births, which 99% of cases occurred in developing countries. Research aims to discover the relationship of antenatal class towards mothers’ knowledge of the dangerous sign during pregnancy. The result showed that there is a relationship of antenatal class towards mothers’ knowledge of dangerous sign during pregnancy, From this result, the researcher concludes that antenatal class could increase mothers’ knowledge of dangerous sign during pregnancy and may decrease the complication risk during the childbirth.


2018 ◽  
Vol 7 (2) ◽  
pp. 14
Author(s):  
Karima Soamole

Abstract : It is estimated that 80% of mothers who gave birth were able to produce milk in quantities sufficient for the purposes of the baby in full without any additional food and according to the World Health Organization recommends breastfeeding until the age of 4-6 months baby. Annually, more than 25,000 babies Indonesia and 1.3 million babies around the world can be saved by exclusive breastfeeding in 1999, while according to the 2000 report, the WHO approximately 1.5 million children die because they are not feeding properly, less than 15% infants worldwide are given for four months of exclusive breastfeeding and complementary feeding is often inappropriate and unsafe. This research is explanatory research because it explains the relationship between independent variables and dependent variable through hypothesis testing. The method used in this study is a survey method with cross sectional study design. The population in this study are all mothers who breastfeed in Puskesmas Kalumata 2012. Knowledge of the highest in the category of knowledge of both 81 (95.3%) and the behavior of the Exclusive breastfeeding is highest among respondents with a good knowledge of the 55 categories (67.9%). Respondents' attitudes toward breastfeeding Exclusive showed much respondeng that supports 54 (63.5%) and 31 (36.5%) that does not support exclusive breastfeeding her baby. Family Support tehadap respondents in the most exclusive breastfeeding: supporting respondents in exclusive breastfeeding her baby 64 (75.3%) and 21 (24.7%) who did not support the.


2021 ◽  
Vol 7 (1) ◽  
pp. 25-32
Author(s):  
Diana Mejía ◽  
Alejandro Gutierrez-Trejo ◽  
Laurent Avila-Chauvet ◽  
Lynette Bonin

Introduction: in response to the pandemic originated by COVID-19, governments placed in practice a series of safety guidelines recommended by the World Health Organization (WHO). In Mexico, one of the decisive actions to prevent the disease's spread was social isolation or lockdown. These rigorous proceedings could increase stress experience or other mental health disorders. One of the coping mechanisms used to avoid stress includes drug use. Objective: the study's goal was to evaluate the relationship between drug use (alcohol, tobacco, and cannabis) and adherence to safety guidelines. Method: the association between the variables was assessed with a series of surveys indicating adherence to safety guidelines and drug use, 475 Mexican participants (56.5% females and 43.4% males) completed the study. Results: the results suggest that most participants had low drug abuse levels before and during social isolation. There was a significant decrease in tobacco, alcohol, and cannabis use in both females and males. Upon analyzing guideline adherence, low alcohol use correlated with the safety behavior scale, while tobacco and cannabis correlated with the preventive behavior scale. Discussion: the current Mexican sample had not used drugs to cope during social isolation.


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