scholarly journals Phagocytic and metabolic activity of neutrophils of rats in the early stages of post-embryonic development under the influence of biologically active substances of the salt extract of Hirudo verbana

2016 ◽  
Vol 7 (2) ◽  
pp. 96-100 ◽  
Author(s):  
R. F. Aminov ◽  
A. K. Frolov
Keyword(s):  
Metabolic Activity ◽  
The Body ◽  
Biologically Active ◽  
Control Group ◽  
Standard Diet ◽  
Immunological Parameters ◽  
Ether Anesthesia ◽  
Saline Extract ◽  
Nbt Test ◽  
Salt Extract

The nitroblue tetrazolium test reflects the degree of activation of oxygen-dependent mechanisms of bactericidal activity of phagocytotic cells, so the increase in nbt-test and phagocytic indices shows increased activation in the bacterial process and enhanced protection with the help of the absorption ability of the cells in the body. We examined females of nonlinear rats after feeding of their offspring, which 2 weeks before and 2 weeks after mating were injected intraperitoneally with antigens of saline extract of medical leeches (4 injections) and the offspring at days 1, 15, 30, 45, 60. The dosage of salt extract antigens was carried out by determining the protein concentrations using the Lowry protein assay. The animals were immobilized using an immobilizing device. The animals were distributed into three groups: the first research and experimental group of animals was subject to the influence of medical leech salt extract antigens to the amount of 0.5 ml (at the rate of 3 µg/g of animal weight); the second group of intact animals was not subject to intervention, the third control group of animals was administered intraperitoneally saline 0.5 ml of 9% saline solution. We studied females after feeding offspring and offspring at 1, 15, 30, 60 days. The animals were kept in vivarium conditions in individual cages on a standard diet. In the experiment we used 60 females of non-linear rats and 300 of their offspring. All animals were decapitated under ether anesthesia. After that, we took blood, made a solution with crystal heparin and examined the laboratory parameters: total number of leukocytes and leukocyte formula. Evaluation of nonspecific resistance of the organism was investigated using tests which characterize the activity of neutrophils (nbt-test, phagocytosis indices). The results of our studies revealed a positive effect of antigens of saline extract of medical leeches on the absorptive and metabolic activity of neutrophils in the females and their offspring in all study periods compared with the control, an increased number of leukocytes, due to the change of the process of differentiation and deposition of cells in immunogenic organs on proliferation. Changes in immunological parameters indicate the immunostimulatory effect of AG ML on leukopoiesis and on the functional activity of neutrophils – the first line of defense against entry into the body of a variety of bacteria, fungi and protozoa. 

Influence of DAFS-25+polizon composition on blood and functional state of liver of steers at fattening

2020 ◽  
pp. 15-18
Author(s):  
Inna R. Kilmetova ◽  
◽  
Igor A. Rodin ◽  
Nazira I. Khayrullina ◽  
Nikolay G. Fenchenko ◽  
...  
Keyword(s):  
Functional State ◽  
White Blood Cells ◽  
Live Weight ◽  
The Body ◽  
Farm Animals ◽  
Control Group ◽  
Standard Diet ◽  
The Impact ◽  
Experimental Group ◽  
Stimulation Of

Summary. The disbalanced feeding and the uneven distribution of micro- and macroelements in the environment leads to a trace element, in particular hypomelanosis. To accelerate the growth and preservation of young farm animals include in the diet of various biological additives and drugs, which include selenium. For stimulation of weight gain in the livestock industry, as well as for the prevention and treatment of pathological processes in addition to micro - and macrouse amino acids, primarily methionine. The aim of this work was to study the influence of composition of DAFS-25+Polizon on morpho-biochemical parameters of blood and functional state of the liver in fattening bulls of black-motley breed in the conditions of the Republic of Bashkortostan. Experiments using were conducted on bull-calves of black-motley breed of the properties in the properties age from 6 to 15 months. The first experimental group during the experiment was additionally given the composition of DAFS-25+Polizon at a dose of 2 mg/kg, the animals of the control group received a standard diet. To assess the impact of the composition DAFS-25+Polizon on metabolism cattle studied morphological and biochemical indicators of blood and conducted histological examination of the liver. It is established that the use of the composition of DAFS-25+Polizon at a dose of 2 mg/kg increases the number of erythrocytes and hemoglobin in the experimental group and reduces the amount of white blood cells. The serum content of total protein, phosphorus and calcium increases in the group of experimental animals. Microscopic examination of the liver revealed no changes in the structure of the organ and hepatocytes in the experimental group, whereas in the control group hemodynamic disorders and dystrophic changes in liver cells were observed. Thus, the use of the composition DAFS-25+Polizon at a dose of 2 mg/kg of live weight in fattening bulls black-and-white breed contributes to the increase of redox processes in the body, stimulation of metabolism, prevent the development of liver disorders of cellular mechanisms of metabolism, optimizes the structure of the liver, which generally provides higher productivity.

scholarly journals THE USE OF BIOSTIMULANT FOR INCREASING THE BODY WEIGHT GAIN OF CHICKENS

2020 ◽  
Vol 17 (35) ◽  
pp. 800-812
Author(s):  
Ilgiz DOLININ ◽  
George BAZEKIN ◽  
Evgeny SKOVORODIN ◽  
Almaz SHARIPOV ◽  
Ivan CHUDOV
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Broiler Chickens ◽  
Body Weight Gain ◽  
Live Weight ◽  
The Body ◽  
New Drugs ◽  
Natural Resistance ◽  
Control Group ◽  
Immunological Parameters

Poultry farming holds a special place in ensuring the products that the consumers demand, it provides the population with essential food products,such as eggs and meat,that contain vital micro and macronutrients, proteins, lipids, and vitamins. Therefore, the issues of rational, economically feasible feeding of meat poultry, namely broiler chickens, are an urgent task. It is also essential to find effective methods of their application in order to correct the natural resistance and immune and biological reactivity of birds. The purpose of this research is to study the effect of the biological stimulant-Nucleostim on the growth and development of chickens, hematological, and immunological parameters of the blood of birds.This Biostimulant is a purified bovine spleen extract containing at least 1 mg / ml of low molecular weight peptides (nucleotides and nucleosides) formed as a result of autolysis, using dry whey and diatomite as fillers. Onthe application ofNucleostim, the gain in live weight of chickens was increased by 9.7%. At the end of the experiment, the livability of the chicks of the experimental group treated with Nucleostimcame up to 88%, compared with the 72% of the control group. The use of biostimulant had a stimulating effect on the liver of chickens confirmed by the research results presented in the article, as well as contributed to the development of the thymus in the setting of general dystrophy. Thus, it improved chicklivability and increased body weight gain. The biological stimulant-Nucleostim as an adaptogenic, anabolic, and immunostimulatory agent is promising for finding new drugs that improve the health and productivity of poultry.

scholarly journals Peculiarities of Evaluation of Biological Effects of the Influence of Electromagnetic Radiation in Conditions of Reduced Temperature (Experiment)

2021 ◽  
Vol 6 (2) ◽  
pp. 227-235
Author(s):  
O. Litovchenko ◽  
◽  
I. Perova ◽  
Keyword(s):  
Electromagnetic Radiation ◽  
Negative Impact ◽  
Biological Effects ◽  
The Body ◽  
Combined Effect ◽  
Male Rats ◽  
Control Group ◽  
Prevention Measures ◽  
Immunological Parameters ◽  
Reduced Temperature

In modern conditions there is a high need to improve methods for establishing the nature of the combined influence of factors using modern approaches for further development of prevention measures against the negative impact of factors on the body. The purpose of the study was to investigate the combined effect of electromagnetic radiation and low temperatures with subsequent determination of the level of contribution of each factor in the formation of biological effects within the experiment by mathematical analysis of data using the method of artificial intelligence. Materials and methods. The subchronic experiment (30 days) was performed on male rats. The animals were divided into groups: combined exposure to electromagnetic radiation (70 kHz, 600 V/m) and reduced temperature (40C), isolated exposure to reduced temperature, isolated exposure to electromagnetic radiation and a control group. The establishment of biological effects was performed at stages 5, 15 and 30 days of the experiment. Changes in the body were assessed by physiological, biochemical and immunological parameters of the blood (30 indicators). Data processing was performed using computational intelligence methods (Neuro-fuzzy system). Results and discussion. The combined effect of the factors was manifested by the following biological effects: intensification of peroxidation processes with simultaneous moderate suppression of antioxidant protection, intensification of lipid metabolism was characterized by dyslipoproteinemia, manifesting in: increase in triglycerides, cholesterol and its fractions. Changes of the immune system were decrease in the ability of neutrophils to phagocytosis at different stages of the experiment, imbalance of the activation of the system of reducing the concentration of C4 at the background of increased intensity of IgM and IgG synthesis. The method of determining the intensity of the factors, developed on the basis of factor and cluster analysis, allowed to determine that during the experiment the ratios between the factors changed, but the greatest contribution was made by reduced temperature by both biochemical parameters (63%) and immunological (53%) at the same time, the level of electromagnetic radiation contribution was 37% and 47%, respectively. Thus, the reduced temperature was the leading factor in the combined effect, which added 60% to the overall biological effect throughout the study, against the effect of electromagnetic radiation for which the level of contribution was only 40%. By means of the factor analysis informative indicators, making it possible to establish the characteristics of biological effects, and therefore leading indicators in formation of biological effects were the increase in concentration of DC with simultaneous decrease in concentration of SH-groups, increase in VLDL and suppression of oxygen-dependent metabolism of neutrophil-test. Conclusion. Thus, the tested mathematical approach allowed to determine the leading role of each of the studied factors under the conditions of their combined influence in different systems, which allows to predict probable appropriate reactions of the whole organism and gives a reasonable approach to the development of preventive measures

scholarly journals BODY IMMUNOLOGICAL REACTIVITY IN OPIOMANIA

2021 ◽  
Vol 23 (4) ◽  
pp. 781-784
Author(s):  
K. K. Kulmukanova ◽  
A. U. Baiduissenova ◽  
E. A. Akhmediyarova ◽  
A. A. Yktiyarov ◽  
G. A. Bekniyazova ◽  
...  
Keyword(s):  
Relative Number ◽  
Neurological Status ◽  
The Body ◽  
Control Group ◽  
Immunological Reactivity ◽  
Immunological Parameters ◽  
Group I ◽  
Opioid Drugs ◽  
Therapeutic Measures ◽  
Opium Addiction

Due to the general trend of changes in reactivity in many exogenous and endogenous diseases, more and more attention is currently being paid to changes in immunological reactivity in drug addiction. The expediency of assessing the state of immune mechanisms in opioid addiction is determined by the need to predict their course and outcome. The aim of the study was to study the immunological reactivity of the body in patients with opium addiction in a stage of abstinence. For this purpose, clinical and immunological studies were conducted in 80 patients who use opioid drugs. The duration of the disease ranged from 0.5-19 years. Of these, the disease duration is up to 3 years – 28 patients (group I), and over 3 years – 52 patients (group II). The number of subjects in the control group was n = 50. Authors carried out the assessment of the mental, narcological, somatic, and neurological status. In addition, they have studied the general clinical, biochemical and immunological parameters As a result of this study, it was found, that patients of group I had more pronounced T-lymphocytopenia. A persistent increase in the value of serum IgM was revealed both in the dynamics of abstinence and depending on the duration of the disease, which may indicate a strain on the humoral link of immunity in opium addiction. In addition, as the duration of chronic narcotization increases, there is a tendency to increase the relative number of B-lymphocytes. Thus, at the patients with opium addiction in a state of abstinence develop T-lymphocytopenia. Moreover, with an increase in the duration of the disease, an increase in the level of IgM by 2-2.6 times. The revealed changes in the immunological reactivity of the organism suggest the need to include immunocorrective therapy in the complex of therapeutic measures for opium addiction. 

Influence of feed additive Vitartil on the productive traits and biochemical parameters of steers’ blood

2021 ◽  
pp. 25-32
Author(s):  
S. S. Mirgalimova ◽  
A. O. Trufanova ◽  
R. R. Fatkullin
Keyword(s):  
Physiological State ◽  
Relative Number ◽  
Blood Parameters ◽  
The Body ◽  
Biologically Active ◽  
Feed Additive ◽  
Control Group ◽  
Vital Functions ◽  
Productive Traits ◽  
Experimental Group

The physiological state of animals is to a certain extent characterized by hematological indicators, since blood occupies a special place in the body. By transferring nutrients and biologically active substances, the blood performs the general regulation of vital functions of the body. The use of Vitartil as a feed additive in the diets of animals leads to an increase in glycolytic processes and a decrease in the body’s need for oxygen delivery, which contributes to the growth of the animal body. The purpose of the research was to study the changes in blood parameters taking into account the age of Hereford steers against the background of the use of Vitartil feed additive to the main diet and its effect on the productive traits of animals. In order to carry out the experiment two groups of steers-analogs of Hereford breed have been formed at the age of 6 months per 10 heads in each. The difference between the groups was that the steers of the experimental group have been received the feed additive Vitartil in addition to the main diet. The greater yield of the meat part was in the steers of the experimental group in comparison with the herdmates of the control group. This indicator in the experimental group was 78,9 %, while in the control group it was lower by 1,6 %. The animals of the experimental group were superior to their herdmates in terms of meat weight by 1,4 kg or by 8,8 %. The relative number of bones was lower in the experimental group and amounted to 18,4 %, and in the control group 19,2 %. The meat content index was high in the steer have been received the biologically active additive Vitartil and was 4,3, and in the control group 4,0. It has been found that the use of Vitartil feed additive to the main diet of Hereford steers increases the blood content of hemoglobin and glucose, which has a certain effect on the morphological and chemical composition of meat, as well as increases its energy value.

COMPARATIVE ASSESSMENT OF THE FUNCTIONAL PROPERTIES OF THE FOOD ADDITIVE «TOMATNAYA» OBTAINED BY VARIOUS TECHNOLOGIES

2021 ◽  
Author(s):  
Е.П. ВИКТОРОВА ◽  
Е.В. ЛИСОВАЯ ◽  
М.В. ЛУКЬЯНЕНКО ◽  
Н.Н. КОРНЕН ◽  
Е.В. КУЗЬМИНОВА ◽  
...  
Keyword(s):  
Functional Properties ◽  
Antioxidant Properties ◽  
Food Additive ◽  
The Body ◽  
Innovative Technology ◽  
Control Group ◽  
Standard Diet ◽  
Tomato Pomace ◽  
White Rats ◽  
Experimental Group

Для получения препаратов и добавок, обладающих антиоксидантными свойствами, представляют интерес выжимки томатов, образующиеся при производстве сока прямого отжима с предварительным отделением семян. Проведена сравнительная оценка эффективности функциональных свойств образцов пищевой добавки, полученных из выжимок томатов по различным технологиям: образец добавки 1 получен по технологии, включающей ИК-сушку выжимок, их охлаждение и измельчение; образец добавки 2 – по инновационной технологии, включающей дополнительную предварительную обработку выжимок в ЭМП СВЧ перед ИК-сушкой. Исследования проводили в течение 30 дней на трех группах лабораторных белых крыс: контрольной, животные которой получали стандартный рацион, и двух опытных, в которых животные помимо основного рациона получали при кормлении индивидуально 1 раз в сутки 2 г добавки образца 1 (1-я опытная группа) или образца 2 (2-я опытная группа). Установлено, что степень снижения концентрации ферментов печени АсАт и АлАт в крови животных 2-й опытной группы соответственно на 10,6 и 11,0% выше, чем в крови животных 1-й опытной группы. Степень снижения содержания диеновых коньюгатов, кетодиенов и малонового диальдегида в крови животных 2-й опытной группы была соответственно на 22,1; 10,1 и 12,7% выше по сравнению с аналогичными показателями животных 1-й опытной группы. Таким образом, доказано, что пищевая добавка «Томатная», выработанная по инновационной технологии, проявляет ярко выраженные антиоксидантные и гепатопротекторные свойства, что обеспечивает нормализацию биохимических процессов в организме, повышает его антиоксидантную защиту и препятствует разрушению мембран клеток. For the obtaining of preparations and additives with antioxidant properties, tomato pomace, formed during the production of direct-pressed juice with preliminary separation of seeds, is of interest. A comparative evaluation of the effectiveness of the functional properties of food additive samples obtained from tomato pomace using various technologies was carried out. The sample of additive 1 was obtained using a technology that includes IR drying of pomace, cooling and grinding; the sample of additive 2 was obtained using a technology that includes additional pretreatment of pomace in microwave EMF before IR drying. The studies were carried out for 30 days on three groups of laboratory white rats: a control group, the animals of which were given a standard diet, and two experimental ones, in which the animals, in addition to the main diet, were given individually once a day with 2 g of an additive of sample 1 (1st experimental group) or sample 2 (2nd experimental group). It was found that the degree of decrease in the concentration of liver enzymes AsAt and AlAt in the blood of animals of the 2nd experimental group was respectively 10,6 and 11,0% higher, than in the blood of animals of the 1st experimental group. The degree of decrease in the content of diene conjugates, ketodienes and malondialdehyde in the blood of animals of the 2nd experimental group was higher respectively by 22,1; 10,1 and 12,7% compared with similar indicators of animals of the 1st experimental group. Thus, it is proved that the food additive «Tomatnaya», developed by innovative technology, shows pronounced antioxidant and hepatoprotective properties, which ensures the normalization of biochemical processes in the body, increases its antioxidant protection and prevents the destruction of cell membranes.

Digestibility of nutrients and energy metabolism in lactating cows when sapropel is included in the ration

2021 ◽  
pp. 22-27
Author(s):  
L. P. Yarmots ◽  
G. A. Yarmots ◽  
A. E. Belenkaya ◽  
M. O. Smyshlyaeva
Keyword(s):  
Energy Metabolism ◽  
Milk Fat ◽  
Animal Husbandry ◽  
Feed Additives ◽  
The Body ◽  
Biologically Active ◽  
Main Trend ◽  
Control Group ◽  
Lactating Cows ◽  
Positive Effect

Unbalanced mineral and vitamin nutrition of lactating cows can be a critical factor in the realization of their productive potential. The development and introduction into production of inexpensive, but effective feed additives is the main trend of improving the feeding of modern animal husbandry. Under the conditions of the Tyumen region such natural raw materials can be sapropels, which successfully combine a variety of biologically active substances. The purpose of the research was to study the digestibility of nutrients and energy metabolism in lactating cows when sapropel is included in the ration. Scientifi c and economic experiment in the study of the effectiveness of feeding sapropel lake Nepryak has been carried out in the training and experimental farm of the State Northern Trans-Urals Agrarian University. The animals of the control group have been fed the main diet. Cows of the 1st and 2nd experimental groups have been fed 300 and 500 g of sapropel per head/day, respectively, in addition to the main ration. It has been found as a result of research that the introduction of sapropel into the ration of cows has a positive effect on the digestibility of nutrients. The digestibility coefficients were higher in the animals of the 1st and 2nd experimental groups compared with the cows of the control group. Cows from the experimental groups digested all the organic substances of the ration better. During the experiment period cows of the 1st and 2nd experimental groups in contrast to the control group had higher milk yield by 11,31 and 10,38 %, respectively, milk protein yield by 10,56 and 5,95 %, milk fat yield by 17,18 and 12,99 %. It has been established that the introduction of sapropel into the ration of cows has the positive effect on the digestibility of nutrients, contributes to the increase of milk productivity, normalizes the metabolism in the body.

scholarly journals A Method to Increase the Viability of Cyprinus Carpio (Linnaeus, 1758) Stocking of the Aquatories Under the Influence Advanced Biotechnologies

2021 ◽  
Vol 21 (4) ◽  
pp. 139-148
Author(s):  
Olena Honcharova ◽  
Pavlo Kutishchev ◽  
Yevgen Korzhov
Keyword(s):  
Body Weight ◽  
Chlorella Vulgaris ◽  
Spirulina Platensis ◽  
Control Diet ◽  
Scientific Work ◽  
Artemia Salina ◽  
The Body ◽  
Biologically Active ◽  
Control Group ◽  
Natural Food

This research investigated Spirulina Platensis, Chlorella vulgaris and Artemia salina as additional sources of protein and biologically active substances that affect the parameters of the carp body. Additional addition of carp to the diet in the ratio: Spirulina Platensis - 40%, Chlorella vulgaris - 30% and Artemia salina - 30% made an impact on the parameters of carp development. The components were cultured in a bioreactor built into a recirculating aquaculture system. The results showed that after additional feeding of carp with the indicated components, the body weight of one-year carp was higher than the control group by 8.9%, and safety by 3.4%. Body weight two year carp was greater in the experimental group than in the group where the fish ate the total diet. The difference was 12.1% in body weight and 2.9% in safety. These parameters were significantly lower in fish fed the control diet (P<0.05). This scientific work has demonstrated the additional use of natural food as a method for improving the blood composition of carp: an increase in hemoglobin by 15.5% (P<0.05), erythrocytes by 5.5% in comparison with the control group. Indicators of gas-discharge visualization of a biological object supplemented the obtained result.

scholarly journals Influence of the probiotic preparation “Plantarum” in the diets of pregnant animals on the growth and development of young animals

2021 ◽  
Vol 37 ◽  
pp. 00143
Author(s):  
Irina Funk ◽  
Nikolay Vladimirov ◽  
Alexander Yashkin ◽  
Lyudmila Pautova ◽  
Vitaly Gorshkov
Keyword(s):  
Body Weight ◽  
Growth And Development ◽  
The Body ◽  
Control Group ◽  
Standard Diet ◽  
Absolute Increase ◽  
Probiotic Preparation ◽  
Positive Effect ◽  
Experimental Group ◽  
Different Doses

The work aims to study the effect of different doses of the experimental probiotic preparation “Plantarum” when fed to pregnant animals on their reproductive qualities, as well as on the growth and development of young animals. To obtain young animals, four groups of goats were formed in the type of the Saanen breed, 20 heads each. In the first (control) group, the animals received a standard diet, in the diet of the animals of the second, third and fourth groups in the second half of pregnancy, the probiotic preparation “Plantarum” was additionally introduced, containing Lactobacillus Plantarum, Propiobacterium freudenreihii, in dosages from 0.4 to 0.8 ml/kg of body weight per day. From the offspring of the goats of the experimental groups, four groups of 12 goats were formed. The highest percentage of preservation (94%) and the highest business output of kids per 100 queens (150%) were observed in the fourth experimental group (0.8 ml). The goats of the second, third and fourth groups exceeded the body weight of their contemporaries from the control group by 3%, 6.3%, and 8.8%. The highest indices of the absolute increase in body weight by age periods were noted in the fourth group of goats. There were no significant differences in body build indices during the experiment between the goats of the control and experimental groups. Thus, the maximum positive effect was observed with the introduction of a probiotic preparation into the diet of pregnant goats at a dose of 0.8 ml/kg of body weight per day.

scholarly journals Efficacy of manganese pantothenate and lysinate chelates for prevention of perosis in broiler chickens

2021 ◽  
Vol 12 (2) ◽  
pp. 289-293
Author(s):  
V. S. Sakara ◽  
A. Y. Melnyk ◽  
V. V. Sakhniuk ◽  
N. V. Vovkotrub ◽  
M. M. Fedorchenko ◽  
...  
Keyword(s):  
Broiler Chickens ◽  
Protein Concentration ◽  
Mineral Metabolism ◽  
The Body ◽  
Clinical State ◽  
Control Group ◽  
Meat Production ◽  
Standard Diet ◽  
Meat Productivity ◽  
Reduced Mobility

Perosis is a common metabolic disease of industrial birds, especially broiler chickens. It leads to a violation of the balance of biotic substances in the body of chickens, which is clinically manifested by the curvature of the limbs, reduced mobility, and, consequently, reduced profitability of meat production. Prevention of perosis is possible provided that chickens receive a sufficient amount of manganese in a biologically available form. Studies were conducted to determine the efficiency of use of manganese chelates (pantothenate and lysinate) for prevention of perosis in broiler chickens. Efficacy was confirmed by examining changes in the clinical state, indicators of protein and mineral metabolism, as well as meat productivity of birds. For the experiment, broiler chickens of the Cobb-500 cross were taken at the age of 14 days. The birds of the control group received a standard diet, and the chickens from two experimental groups additionally received manganese pantothenate and lysinate with water during the critical period for the development of perosis – 14–28 days old. After 14 days of administration of manganese pantothenate and lysinate, the weight of the experimental birds at the age of 28 days was greater by 133.6 g (+11.0%) and 142.2 g (+11.7%), respectively, in comparison with poultry of the control group. Additional provision of manganese pantothenate and lysinate to chickens of the experimental groups contributed to an increase in the blood serum total protein concentration by 11.0% and 12.8 %, albumin – by 10.1% and 8.2%, magnesium – by 8.1% and 9.0% and manganese – by 29.6% and 26.9%, respectively, compared with indicies of the control group birds. The use of manganese chelates in the form of pantothenate (0.2 mL/L of water) and a lysinate (0.5 mL/L) during the 14–28th days of broiler chickens’ rearing provides 100% prevention of perosis. This reduces the death of broiler chickens, increases body weight, and, as a result, significantly increases the profitability of meat production.

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