scholarly journals Морфологічні зміни тимусу курчат при різних схемах антибактеріальної терапії

2017 ◽  
Vol 19 (73) ◽  
pp. 11-18
Author(s):  
L.Y. Lyzogub
Keyword(s):  
Antibacterial Agents ◽  
Normal Development ◽  
Negative Impact ◽  
Preventive Treatment ◽  
Antibacterial Drug ◽  
Antibacterial Drugs ◽  
Main Thing ◽  
The Moment ◽  
The One ◽  
Positive Effect

The maximum number of products at the lowest cost – is the main thing, what modern poultry industry can be characterized. One of the most pressing problems at the moment is early antibiotic therapy and the associated safety of young poultry early age. In this regard, of particular interest for this study is how the most widely used antibacterial drugs effects on the one of key organs of the immune system – thymus. The article presents the data obtained in the course of the experiment, which determines how preventive treatment schemes, that includes usage single and multiple antibacterial drugs, influenced on the morphological status of the chickens thymus. We selected scheme and a combination of antibacterial drugs have not been studied previously. That was compared with the usage of probiotic Bolmol at the same treatment scheme. A comparison of morpho-functional state of the thymus of chickens 15-, 22- and 41-days-old, when applying several treatments schemes. The schemes of treatment included: the usage of one or two antibiotics during the cycle, compared with the usage of probiotic. We made the conclusions about the absence of the negative impact of selected drugs on the morphofunctional state of the thymus and the positive effect of probiotic «Bolmol». The morphometric parameters of the cortex and medulla in the lobules of the thymus of chicks 15-day-old, taking as an antibacterial drug probiotic Bolmol, were not significantly different from control values and were statistically significant when compared with chicks who used antibiotics: the width of the cortical area was on 15% and 29.09% wider then chickens receiving antibiotic treatment. This indicates a positive effect of probiotic Bolmol compared with antibacterial agents which were chosen. Thus, these data demonstrate that the use of probiotics in cyclic schemes of antibiotic prophylaxis contribute to the normal development of the thymus, which in turn leads to increased resistance and preservation of poultry. Was given the substantiation about safely usage of cyclic schemes of antibacterial drugs in the event of objective necessity.

scholarly journals Prospects of the use of prebiotics in broiler poultry farming as an alternative to antibiotics

2021 ◽  
Vol 37 ◽  
pp. 00156
Author(s):  
Aleksei Reznichenko ◽  
Liudmila Reznichenko ◽  
Vasilij Dorozhkin ◽  
Sergej Noskov ◽  
Svetlana Vodianitskaia
Keyword(s):  
Body Weight ◽  
Broiler Chickens ◽  
Antibacterial Agents ◽  
Natural Resistance ◽  
Partial Replacement ◽  
Wide Spread ◽  
Antibacterial Drugs ◽  
Almost All ◽  
Positive Effect ◽  
Poultry Farming

The uncontrolled use of antibacterial drugs resulted in a wide spread of forms of microorganisms resistant to them. The resistance of most bacteria to one degree or another is observed in relation to almost all existing antibiotics, which led to a significant decrease in the effectiveness of their use not only in veterinary medicine but also in medicine. Therefore, an important task which veterinary service faces is the use of alternative antibacterial drugs. Thus, the development and use of prebiotics in the food of poultry for complete or partial replacement of antibiotics is considered as a new direction of modern scientific research. The authors were the first who studied the effect of the heteropolysaccharides “raspol” and “vetelac” on the organism of broiler chickens. A high pharmacological effect of both drugs was established with a clear advantage of raspol, the use of which, against the background of the absence of antibiotics, had a positive effect on the growth and viability of poultry and caused an increase in the natural resistance of organisms. Thus, prebiotic raspol can be used as an alternative to antibacterial agents in broiler poultry farming. This drug is recommended for the give to broiler chickens with water at the rate of 0.6 g / kg of body weight starting from 7 days of age for 10 days.

Pengaruh Kepercayaan Terhadap Loyalitas Konsumen Yang Memunculkan Distrust

2019 ◽  
Vol 3 (2) ◽  
pp. 100-112
Author(s):  
Septian Wahyudi
Keyword(s):  
Research Method ◽  
Negative Impact ◽  
Consumer Confidence ◽  
Consumer Loyalty ◽  
The One ◽  
Loyal Customers

The company certainly wants to increase its sales and increase the number of its customers so that all efforts and methods are carried out, including in building consumer confidence, thus making these consumers become loyal customers or commonly referred to as customers. But on the one hand the trust built by the company actually has a negative impact, namely the emergence of distrust because the frequency of the company offers a variety of products that are sometimes not needed by consumers, this paper is made to answer these phenomena and problems in a concise manner.This research method is by analyzing criticism of several studies about trust that affect consumer loyalty which results in the absence of influence between trust in consumer loyalty.

The Munich conference of Minister-Presidents of German lands in 1947

2020 ◽  
Vol 2020 (10-2) ◽  
pp. 86-98
Author(s):  
Ivan Popov
Keyword(s):  
The State ◽  
State Governments ◽  
The West ◽  
Constitutional Development ◽  
The Moment ◽  
The One

The paper deals with the organization and decisions of the conference of the Minister-Presidents of German lands in Munich on June 6-7, 1947, which became the one and only meeting of the heads of the state governments of the western and eastern occupation zones before the division of Germany. The conference was the first experience of national positioning of the regional elite and clearly demonstrated that by the middle of 1947, not only between the allies, but also among German politicians, the incompatibility of perspectives of further constitutional development was existent and all the basic conditions for the division of Germany became ripe. Munich was the last significant demonstration of this disunity and the moment of the final turn towards the three-zone orientation of the West German elite.

CHANGES IN THE GENEALOGICAL STRUCTURE OF THE BREEDING STOCK OF THE YAROSLAVL BREED IN THE VOLOGDA REGION

2020 ◽  
pp. 24-29
Author(s):  
N.I. ABRAMOVA ◽  
G.S. VLASOVA ◽  
O.L. KHROMOVA
Keyword(s):  
Protein Content ◽  
Negative Impact ◽  
Breeding Stock ◽  
Holstein Breed ◽  
Vologda Region ◽  
Ideal Line ◽  
Productivity Potential ◽  
New Generation ◽  
Modern Population ◽  
Positive Effect

Проведен сопоставительный анализ генеалогической структуры племенного поголовья ярославской породы Вологодской области по данным 2005 и 2018 годов. Установлено, что в 2005 году в структуру породы входили 8 отечественных генеалогических линий. В результате скрещивания с голштинской породой произошли значительные изменения. Доля животных, принадлежащих к линиям ярославской породы, уменьшилась со 100% в 2005 году до 35,3% в 2018 году. В генеалогическую структуру современной популяции добавились 3 линии голштинской селекции, к которым на 1.01.2019 года относится большая часть маточного поголовья: к линии Рефлекшн Соверинга 198998 — 42,9%, Вис Бэк Айдиала 1013415 — 13%, Монтвик Чифтейна 95679 — 8,8%. Скрещивание с голштинской породой оказало положительное влияние на повышение молочной продуктивности животных ярославской породы. Средний надой на 1 корову увеличился на 1670 кг молока, доля коров с продуктивностью более 6000 кг молока выросла на 35%. В результате расчета корреляционной зависимости между кровностью по голштинской породе и массовой долей жира и белка в молоке установлено, что скрещивание не ухудшило качественные показатели молока коров ярославской породы (степень кровности с МДЖ — r=-0,01; с МДБ — r=0,09; P<0,01), но в то же время отразилось отрицательно на продолжительности хозяйственного использования животных в стаде (r=-0,27; P<0,001). Для дальнейшего совершенствования породы следует определить оптимальную степень прилития крови голштинской породы. А с целью сохранения генофонда необходимо получение нового поколения чистопородных быков ярославской породы с более высоким потенциалом продуктивности. The authors conduct a comparative analysis of the genealogical structure of the breeding stock of the Yaroslavl breed in the Vologda region on the basis of the data for 2005 and 2018. It is established that in 2005 the structure of the breed included 8 domestic genealogical lines. As a result of the crossing with the Holstein breed, significant changes occurred. The share of animals of the Yaroslavl breed lines decreased from 100% in 2005 to 35.3% in 2018. The genealogical structure of the modern population got 3 added lines of the Holstein selection which as of 1.01.2019 include most of the breeding stock: Reflection Sovering line 198998 - 42.9%, Vis Back Ideal line 1013415 - 13%, and Montwick Chieftain line 95679 - 8.8%. The crossing with the Holstein breed had a positive effect on the increase in the milk productivity of the Yaroslavl breed animals. The average milk yield per 1 cow increased by 1670 kg of milk and the share of cows with the productivity of more than 6000 kg of milk increased by 35%. The results of the calculations of the correlation between the Holstein thoroughbredness and the fat and protein content in the milk showed that the crossing did not impair the quality indicators of the milk the Yaroslavl breed cows (thoroughbredness degree with the fat content r=-0.01; with the protein content r=0.09 P<0.01), but at the same time had a negative impact on the duration of the economic use of the animals in the herd (r=-0.27; P<0.001). For further improvement of the breed, there is a need to determine the optimal degree of crossing with the Holstein breed. Also, in order to preserve the gene pool, there is a need to obtain a new generation of purebred bulls of the Yaroslavl breed with a higher productivity potential.

A Review on Quantum Dots: Synthesis to In- silico Analysis as Next Generation Antibacterial Agents

2019 ◽  
Vol 20 (3) ◽  
pp. 255-262 ◽  
Author(s):  
Sounik Manna ◽  
Munmun Ghosh ◽  
Ranadhir Chakraborty ◽  
Sudipto Ghosh ◽  
Santi M. Mandal
Keyword(s):  
Quantum Dots ◽  
Pathogenic Bacteria ◽  
Antibacterial Agents ◽  
Antimicrobial Properties ◽  
Binding Potential ◽  
Antibacterial Drug ◽  
Next Generation ◽  
Mechanism Of Reaction ◽  
High Level ◽  
Membrane Components

Succumbing to Multi-Drug Resistant (MDR) bacteria is a great distress to the recent health care system. Out of the several attempts that have been made to kill MDR pathogens, a few gained short-lived success. The failures, of the discovered or innovated antimicrobials, were mostly due to their high level of toxicity to hosts and the phenomenal rate of developing resistance by the pathogens against the new arsenal. Recently, a few quantum dots were tested against the pathogenic bacteria and therefore, justified for potential stockpiling of next-generation antibacterial agents. The key players for antimicrobial properties of quantum dots are considered to be Reactive Oxygen Species (ROS). The mechanism of reaction between bacteria and quantum dots needs to be better understood. They are generally targeted towards the cell wall and membrane components as lipoteichoic acid and phosphatidyl glycerol of bacteria have been documented here. In this paper, we have attempted to simulate ZnS quantum dots and have analysed their mechanism of reaction as well as binding potential to the above bacterial membrane components using CDOCKER. Results have shown a high level of antibacterial activity towards several pathogenic bacteria which specify their potentiality for future generation antibacterial drug development.

The study of Apara (placenta) and its correlation with the Prakriti and Weight of newborn

2017 ◽  
Vol 2 (05) ◽  
Author(s):  
Apurva Dhakulkar ◽  
Sachin Khedikar
Keyword(s):  
Basic Concept ◽  
Normal Development ◽  
Unique Contribution ◽  
Multiple Functions ◽  
Intrauterine Life ◽  
Foetal Growth ◽  
Healthy Pregnancy ◽  
The One

The placenta is the most important and the only organ between mother and foetus serving multiple functions like endocrinal, respiratory and metabolic. Normal development of the placenta is the one of the important requirements for a healthy pregnancy, regulating foetal growth and foetal health so that formation of the healthy progeny. In cotemporary sciences many researches are going in the aim of formation of healthy progeny. Apara is the vital feature related to Garbha Sharira in Ayurveda, but its description is in a Sutra form. Hence this study is an humble attempt to explore the concept of ‘Ayurveda Garbha Sharira’ by studying the description of Apara trying to establishment of the assessment of correlation between features of placenta with that of Prakriti is more instinct for this study. Prakriti is the basic concept of Ayurveda. It forms in intrauterine life by combination of Shukra and Shonita. However we do not find direct references of Apara relation with the Prakriti of newborn in Ayurveda. This study intends to fill in the lacunae of both the disciplines by knowledge of integration. If this study establishes some parameters based on the characteristics of Apara with weight and Prakriti of newborn then it will be the unique contribution for Ayurveda Garbha Sharira.

scholarly journals Monitoring the variation in the gut microbiota of captive woolly monkeys related to changes in diet during a reintroduction process

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Camilo Quiroga-González ◽  
Luis Alberto Chica Cardenas ◽  
Mónica Ramírez ◽  
Alejandro Reyes ◽  
Camila González ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Site Conditions ◽  
Microbiota Composition ◽  
Microbial Composition ◽  
Bacterial Composition ◽  
Diet Diversity ◽  
Woolly Monkeys ◽  
The Moment ◽  
Positive Effect ◽  
Lagothrix Lagothricha

AbstractMicrobiome is known to play an important role in the health of organisms and different factors such as diet have been associated with modifications in microbial communities. Differences in the microbiota composition of wild and captive animals has been evaluated; however, variation during a reintroduction process in primates has never been reported. Our aim was to identify changes in the bacterial composition of three individuals of reintroduced woolly monkeys (Lagothrix lagothricha) and the variables associated with such changes. Fecal samples were collected and the V4 region of the 16S rRNA gene was sequenced to determine gut microbial composition and functionality. Individual samples from released individuals showed a higher microbial diversity after being released compared to before liberation, associated with changes in their diet. Beta diversity and functionality analysis showed separation of samples from released and captive conditions and the major factor of variation was the moment of liberation. This study shows that intestinal microbiota varies depending on site conditions and is mainly associated with diet diversity. The intake of food from wild origin by released primates may promote a positive effect on gut microbiota, improving health, and potentially increasing success in reintroduction processes.

scholarly journals Carabid Beetle (Coleoptera: Carabidae) Response to Soil Properties of Urban Wastelands in Warsaw, Poland

2020 ◽  
Vol 12 (24) ◽  
pp. 10673
Author(s):  
Axel Schwerk ◽  
Marzena Wińska-Krysiak ◽  
Arkadiusz Przybysz ◽  
Ewa Zaraś-Januszkiewicz ◽  
Piotr Sikorski
Keyword(s):  
Negative Impact ◽  
Carabid Beetle ◽  
Carabid Beetles ◽  
Soil Parameters ◽  
City Development ◽  
Space Management ◽  
Trade Offs ◽  
Beetle Assemblages ◽  
Trace Element Contamination ◽  
The One

Urban wasteland is of special interest to city planners. However, to integrate such areas into city space management with consideration of nature conservation aspects, a sound assessment of their ecological potential is necessary. The aim of this paper was to analyze whether carabid beetle assemblages of the wastelands are affected by soil parameters, particularly trace element contamination. Therefore, we studied the carabid fauna in relation to selected soil parameters on 56 sampling plots situated in 24 wastelands located in the city of Warsaw (Poland). The results have confirmed our assumptions that the number of species, as well as the number of individual carabid beetles, are negatively affected by an increasing amount of pollutants in the soil. Particularly, the trace elements Pb, Cu, and Cd showed a significantly negative impact. The results are of value when it comes to the use of urban wastelands in the context of sustainable city development. Future use of urban wastelands will be faced with trade-offs between the use for public interests (e.g., housing space) and ecological interests. Phytoremediation and entomoremediation may be included in decontamination measures. The results of studies, such as the one conducted by us, may help to select the respective wastelands for certain purposes.

scholarly journals A procedure for the introduction of leanness into a company

2021 ◽  
Author(s):  
Davorin Cimermančič ◽  
Janez Kušar ◽  
Tomaž Berlec
Keyword(s):  
Negative Impact ◽  
General Procedure ◽  
Portfolio Analysis ◽  
The Other ◽  
Business Operations ◽  
Step Procedure ◽  
The One ◽  
A Company

AbstractChanging a traditional company into a lean one is a very complex and time-consuming process that needs to be addressed in an appropriate way, otherwise the project of introduction of leanness into a company may fail on the one hand and even have a negative impact on business operations of the company on the other. When introducing a change, a step-by-step procedure leading to a progress may be of great help. The paper outlines a general procedure of leanness, an important part of which is a lean agent. A portfolio analysis is also used as a measure of leanness or as an indicator of the desired direction. The applied working methods were mainly active workshops and interviews with employees. The procedure has been tested on an example of a Slovene company; first, the existing situation is outlined, then the leanness steps taken according to the procedure and the final result after the first transition of the procedure.

scholarly journals Efficacy of the Treatment of Developmental Language Disorder: A Systematic Review

2021 ◽  
Vol 11 (3) ◽  
pp. 407
Author(s):  
Sara Rinaldi ◽  
Maria Cristina Caselli ◽  
Valentina Cofelice ◽  
Simonetta D’Amico ◽  
Anna Giulia De Cagno ◽  
...  
Keyword(s):  
Language Disorder ◽  
Negative Impact ◽  
Receptive Vocabulary ◽  
Primary School Children ◽  
Control Group ◽  
Developmental Language Disorder ◽  
Expressive Vocabulary ◽  
Phonological Skills ◽  
Syntactic Skills ◽  
Positive Effect

Background. Language disorder is the most frequent developmental disorder in childhood and it has a significant negative impact on children’s development. The goal of the present review was to systematically analyze the effectiveness of interventions in children with developmental language disorder (DLD) from an evidence-based perspective. Methods. We considered systematic reviews, meta-analyses of randomized controlled trials (RCTs), control group cohort studies on any type of intervention aimed at improving children’s skills in the phono-articulatory, phonological, semantic-lexical, and morpho-syntactic fields in preschool and primary school children (up to eight years of age) that were diagnosed with DLD. We identified 27 full-length studies, 26 RCT and one review. Results. Early intensive intervention in three- and four-year-old children has a positive effect on phonological expressive and receptive skills and acquisitions are maintained in the medium term. Less evidence is available on the treatment of expressive vocabulary (and no evidence on receptive vocabulary). Intervention on morphological and syntactic skills has effective results on expressive (but not receptive) skills; however, a number of inconsistent results have also been reported. Only one study reports a positive effect of treatment on inferential narrative skills. Limited evidence is also available on the treatment of meta-phonological skills. More studies investigated the effectiveness of interventions on general language skills, which now appears as a promising area of investigation, even though results are not all consistent. Conclusions. The effectiveness of interventions over expressive and receptive phonological skills, morpho-syntactic skills, as well as inferential skills in narrative context underscores the importance that these trainings be implemented in children with DLD.

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