scholarly journals Pomegranate, fruit of the desert, a functional food, and a healthy diet

2021 ◽  
Vol 13 (3) ◽  
pp. 11085
Author(s):  
Mohamad H. SHAHRAJABIAN ◽  
Wenli SUN ◽  
Qi CHENG
Keyword(s):  
Functional Food ◽  
Cultural Beliefs ◽  
Modern Medicine ◽  
Pomegranate Juice ◽  
Pharmacological Activities ◽  
Traditional Medicinal Plants ◽  
Wide Range ◽  
The Family ◽  
Pomegranate Fruit ◽  
Chemical Contents

Traditional medicinal plants contain various ranges of chemical contents and they have become popular because of effectiveness, frequently inadequate provision of modern medicine, preferences and cultural beliefs. Pomegranate belongs to the family of Punicaceae, and its various pharmacological activities are due to presence of wide range of bioactive compounds. The current searching was done by the keywords in main indexing systems including PubMed/MEDLINE, Scopus, and Institute for Scientific Web of Science as well as the search engine of Google Scholar. The keywords were traditional medicine, health benefits, pharmaceutical science, pomegranate, punicalin, punicalagin, and ellagitannins. Major polyphenols in peel and juice of pomegranate are flavonoids such as flavonols (catechin, epicatechin, gallocatechin), condensed tannins, phenolic acids such as gallic, ellagic and caffeic, hyrolysable tannins such as ellagitannins and gallotannins. The main organic acids in pomegranate juice are malic and citric, and in seed is fatty acids (punicic). The major alkaloids and lignans in peel are punigratane and isolariciresinol, respectively. Pomegranate fruit has been proven to act against various diseases like cancer, cardiovascular disorders, diabetes, AIDS, Alzheimer’s disease, male infertility, inflammation, coronary heart disease, and aging. The review summarizes the beneficial impacts of pomegranate which is recommended for consumption. Pomegranate is a high potential natural functional food due to its high pharmacological activities as an ancient efficacious natural drug.

scholarly journals VALERIANA JATAMANSI: AN ETHNOBOTANICAL REVIEW

2018 ◽  
Vol 11 ◽  
Author(s):  
Afroz Patan
Keyword(s):  
Molecular Mechanism ◽  
Skin Diseases ◽  
Chemical Constituents ◽  
Modern Medicine ◽  
Therapeutic Use ◽  
Perennial Herb ◽  
Pharmacological Activities ◽  
Valeriana Jatamansi ◽  
The Family ◽  
Medicinal Properties

 Objective: The main objective of review is an effort to give detailed information on Valeriana jatamansi and its multiple medicinal properties. Methods: As per the literature, the plant V. jatamansi is a perennial herb and found at subtemperate Himalayan regions of the Kumaon and Garhwal. The plant most popularly known as “Valerian.” The plant belongs to the family Valerianaceae. The roots and rhizomes of the plants are traditionally used to treat ulcers, jaundice, dry cough, seminal weakness, skin diseases, leprosy, and for sleep enhancement due to the presence of a variety of different chemical constituents such as sesquiterpenes, coumarins, iridoids, lignanoids, alkaloids, and flavonoids. From literature, the reported methods performed for different pharmacological activities have been thoroughly discussed and complied. Results: Most of the studies compiled from literature shown that V. jatamansi possess antimicrobial, antioxidant, anti-inflammatory, cytotoxic, anxiolytic, and neuroprotective activities. Conclusion: The review reveals that continuous research on this plant is needed to know the exact molecular mechanism and further elaborative studies can lead to develop safe therapeutic use in modern medicine.

Syntheses, Biological and Material Significance of Dihydro[1,3]oxazine Derivatives: An Overview

2020 ◽  
Vol 24 ◽  
Author(s):  
Ankit Lathwal ◽  
Bijoy P. Mathew ◽  
Mahendra Nath
Keyword(s):  
Raw Materials ◽  
Biologically Active ◽  
Pharmacological Activities ◽  
Phenolic Resins ◽  
Good Thermal Stability ◽  
Wide Range ◽  
The Family ◽  
Anti Hiv ◽  
Volatile Materials ◽  
Oxazine Derivatives

: Dihydro[1,3]oxazines are an important class of heterocyclic compounds having a wide range of biological and material properties. Medicinally, they possess diverse pharmacological activities such as bactericidal, fungicidal, microbiocidal, antitumor, anti-HIV and anti-inflammatory agents. Apart from being biologically active, they are materially useful for making polybenzoxazines. Polybenzoxazines, a novel class of non-conjugated thermosetting materials that belong to the family of addition-curable phenolic resins. They have lucrative properties such as small shrinkage in curing, low water absorption, good thermal stability, no release of volatile materials during cure, no need for catalyst and inexpensive raw materials. Further, the flexibility in designing a monomer gives polybenzoxazines an additional edge over ordinary phenolic resins. This review briefly describes the syntheses including eco-friendly strategies, biological and material significance of various dihydro[1,3]oxazine derivatives.

Therapeutic Potential of Cinnoline Core: A Comprehensive Review

2020 ◽  
Vol 20 (3) ◽  
pp. 196-218
Author(s):  
Rajiv K. Tonk ◽  
Sandhya Bawa ◽  
Deepak Kumar
Keyword(s):  
Heterocyclic Compounds ◽  
Therapeutic Potential ◽  
Biological Properties ◽  
Present Review ◽  
Natural Occurrence ◽  
Pharmacological Activities ◽  
Comprehensive Review ◽  
Wide Range ◽  
The Family ◽  
Almost All

Cinnoline or Benzo-pyridazine has its place in the family of fairly well-known benzfuseddiazine heterocycles. Because of its natural occurrence and synthetic exploration, cinnoline compounds validated its thought-provoking bioactivity through a number of research publications and patents during last few decades. A creative consideration has been rewarded to the synthesis of cinnoline based heterocyclic compounds, mostly due to their wide range of diverse pharmacological activities. The present review covers the principle approaches to the synthesis of cinnoline nucleus and almost all biological properties of 115 cinnoline derivatives reported during the last 65 years from natural and synthetic origin with 140 references.

scholarly journals Influence of Ellagitannins Extracted by Pomegranate Fruit on Disulfide Isomerase PDIA3 Activity

Nutrients ◽  
2019 ◽  
Vol 11 (1) ◽  
pp. 186 ◽  
Author(s):  
Fabio Altieri ◽  
Francesco Cairone ◽  
Flavia Giamogante ◽  
Simone Carradori ◽  
Marcello Locatelli ◽  
...  
Keyword(s):  
Ellagic Acid ◽  
Functional Food ◽  
Antioxidant Properties ◽  
Redox Activity ◽  
Degenerative Diseases ◽  
Cellular Functions ◽  
Disulfide Isomerase ◽  
Parkinson’S Diseases ◽  
Wide Range ◽  
Pomegranate Fruit

Pomegranate fruit is a functional food of high interest for human health due to its wide range of phytochemicals with antioxidant properties are implicated in the prevention of inflammation and cancer. Ellagitannins, such as punicalagin and ellagic acid, play a role as anti-atherogenic and neuroprotective molecules in the complex fighting against the degenerative diseases. The aim of this work was to evaluate the composition in punicalagins and ellagic acid of differently obtained extracts from whole fruit, peels and juices, prepared by squeezing or by centrifugation, of pomegranate belonging to different cultivars. Moreover, a wider phenolic fingerprint was also determined. The bioactivity of the extracts was tested on the redox activity of PDIA3 disulfide isomerase, an enzyme involved in the regulation of several cellular functions and associated with different diseases such as cancer, prion disorders, Alzheimer’s and Parkinson’s diseases. The results demonstrate that the different ratios between punicalagin and ellagic acid modulate the enzyme activity and other ellagitannins could interfere with this activity.

scholarly journals A Review: The extraction of active compound from Cymbopogon sp. and its potential for medicinal applications

2018 ◽  
Vol 5 (1) ◽  
pp. 82-98
Author(s):  
Shuhada A. Muttalib ◽  
Raihana Edros ◽  
Nor Azah M. A. ◽  
Rajaletchumy V. Kutty
Keyword(s):  
Pharmaceutical Industry ◽  
Bioactive Compounds ◽  
Plant Extracts ◽  
Active Compound ◽  
Biological Activities ◽  
Cymbopogon Citratus ◽  
High Demand ◽  
Pharmacological Activities ◽  
Wide Range ◽  
The Family

Cymbopogon citratus and Cymbopogon nardus are plants categorized under the family of Poaceae that have been recognized with high demand in pharmaceutical industry for its wide range of pharmacological activities. The potential bioactive compounds can be obtained either through traditional or conventional methods. The plant extracts are commonly used in numbers of products for culinary, pesticides and cosmetic purposes for its flavours and fragrances. Besides, bioactive compounds extracted from both species possess good biological activities that can be applied in the pharmaceutical field.

scholarly journals Bunium persicum: A Review of Ethnopharmacology, Phytochemistry, and Biological Activities

2020 ◽  
Author(s):  
Zahra Majidi ◽  
Fatemeh Bina ◽  
Niloofar Kahkeshani ◽  
Roja Rahimi
Keyword(s):  
Biological Activities ◽  
Chemical Constituents ◽  
Antimicrobial Activities ◽  
Modern Medicine ◽  
Pharmacological Activities ◽  
Bunium Persicum ◽  
Comprehensive Information ◽  
Wide Range ◽  
Coa Reductase ◽  
Biological And Pharmacological Activities

Bunium persicum (Boiss) B. Fedtsh (Apiaceae, Persian name: Zireh Kermani) has been used to treat various diseases in traditional and folkloric medicine including gastrointestinal, respiratory, nasopharyngeal, cardiac, ocular, neurological, rheumatological and urinary tract diseases. Its essential oil contains different monoterpenes, sesquiterpenes and phenyl propenes. Other chemical constituents identified in B. persicum are phenolic compounds, fatty acids, carboxylic acids, and carbohydrates. Wide range of biological and pharmacological activities including antioxidant, analgesic, anti-inflammatory, acetylcholinesterase inhibitory, anticonvulsant, HMG-CoA reductase inhibitory, anti-pancreatic lipase, anticancer, antidiabetic, antihistamine, antidiarrheal, antispasmodic, antihematoxic, antityrosinase and antimicrobial activities have been reported from this plant in modern medicine. This article summarizes comprehensive information attributing traditional uses, phytochemistry, and pharmacological activities of Zireh Kermani.

scholarly journals Mallotus philippinensisMuell. Arg (Euphorbiaceae): Ethnopharmacology and Phytochemistry Review

2014 ◽  
Vol 2014 ◽  
pp. 1-13 ◽  
Author(s):  
Mayank Gangwar ◽  
R. K. Goel ◽  
Gopal Nath
Keyword(s):  
Biological Activities ◽  
Safety Data ◽  
Modern Medicine ◽  
Subtropical Region ◽  
Small Tree ◽  
Pharmacological Activities ◽  
Protein Inhibition ◽  
Wide Range ◽  
Perennial Shrub ◽  
Different Parts

Mallotus philippinensisMuell. Arg (Euphorbiaceae) are widely distributed perennial shrub or small tree in tropical and subtropical region in outer Himalayas regions with an altitude below 1,000 m and are reported to have wide range of pharmacological activities.Mallotus philippinensisspecies are known to contain different natural compounds, mainly phenols, diterpenoids, steroids, flavonoids, cardenolides, triterpenoids, coumarins, isocoumarins, and many more especially phenols; that is, bergenin, mallotophilippinens, rottlerin, and isorottlerin have been isolated, identified, and reported interesting biological activities such as antimicrobial, antioxidant, antiviral, cytotoxicity, antioxidant, anti-inflammatory, immunoregulatory activity protein inhibition against cancer cell. We have selected all the pharmacological aspects and toxicological and all its biological related studies. The present review reveals thatMallotus philippinensisis a valuable source of medicinally important natural molecules and provides convincing support for its future use in modern medicine. However, the existing knowledge is very limited aboutMallotus philippinensisand its different parts like steam, leaf, and fruit. Further, more detailed safety data pertaining to the acute and subacute toxicity and cardio- and immunotoxicity also needs to be generated for crude extracts or its pure isolated compounds. This review underlines the interest to continue the study of this genus of the Euphorbiaceae.

scholarly journals Sweet Marjoram

2016 ◽  
Vol 22 (1) ◽  
pp. 175-185 ◽  
Author(s):  
Fatemeh Bina ◽  
Roja Rahimi
Keyword(s):  
Phenolic Compounds ◽  
Neurological Disorders ◽  
Chemical Constituents ◽  
Modern Medicine ◽  
Pharmacological Activities ◽  
Comprehensive Information ◽  
Wide Range ◽  
Inhibitory Activities ◽  
Origanum Majorana ◽  
Antibacterial And Antifungal

Origanum majorana L. commonly known as sweet marjoram has been used for variety of diseases in traditional and folklore medicines, including gastrointestinal, ocular, nasopharyngeal, respiratory, cardiac, rheumatologic, and neurological disorders. Essential oil containing monoterpene hydrocarbons and oxygenated monoterpenes as well as phenolic compounds are chemical constituents isolated and detected in O majorana. Wide range of pharmacological activities including antioxidant, hepatoprotective, cardioprotective, anti-platelet, gastroprotective, antibacterial and antifungal, antiprotozoal, antiatherosclerosis, anti-inflammatory, antimetastatic, antitumor, antiulcer, and anticholinesterase inhibitory activities have been reported from this plant in modern medicine. This article summarizes comprehensive information concerning traditional uses, phytochemistry, and pharmacological activities of sweet marjoram.

Quantitative and Qualitative Methods of Studying the Processes of Socialization of a Modern Teenager

2020 ◽  
pp. 102-109
Author(s):  
Svetlana Alekseevna Raschetina ◽  
Keyword(s):  
Research Methods ◽  
Interpersonal Relations ◽  
Internet Communication ◽  
Socialization Process ◽  
Wide Range ◽  
The Family ◽  
Modern Family ◽  
Making Friends ◽  
Main Support

Relevance and problem statement. Modern unstable society is characterized by narrowing the boundaries of controlled socialization and expanding the boundaries of spontaneous socialization of a teenager based on his immersion in the question arises about the importance of the family in the process of socialization of a teenager in the conditions of expanding the space of socialization. There is a need to study the role of the family in this process, to search, develop and test research methods that allow us to reveal the phenomenon of socialization from the side of its value characteristics. The purpose and methodology of the study: to identify the possibilities of a systematic and anthropological methodology for studying the role of the family in the process of socialization of adolescents in modern conditions, testing research methods: photo research on the topic “Ego – I” (author of the German sociologist H. Abels), profile update reflexive processes (by S. A. Raschetina). Materials and results of the study. The study showed that for all the problems that exist in the family of the perestroika era and in the modern family, it acts for a teenager as a value and the first (main) support in the processes of socialization. The positions well known in psychology about the importance of interpersonal relations in adolescence for the formation of attitudes towards oneself as the basis of socialization are confirmed. Today, the frontiers of making friends have expanded enormously on the basis of Internet communication. The types of activities of interest to a teenager (traditional and new ones related to digitalization) are the third pillar of socialization. Conclusion. The “Ego – I” method of photo research has a wide range of possibilities for quantitative and qualitative analysis of the socialization process to identify the value Pillars of this process.

THE VALUE OF LOVE IN THE SYSTEM OF FORMATION OF THE PROFESSIONAL MATURITY OF THE EDUCATOR

2020 ◽  
Vol 1 (10(79)) ◽  
pp. 12-18
Author(s):  
G. Bubyreva
Keyword(s):  
Russian Federation ◽  
The State ◽  
Educational Process ◽  
Wide Range ◽  
The Family ◽  
The Russian Federation ◽  
The Government ◽  
The Individual ◽  
The Right

The existing legislation determines the education as "an integral and focused process of teaching and upbringing, which represents a socially important value and shall be implemented so as to meet the interests of the individual, the family, the society and the state". However, even in this part, the meaning of the notion ‘socially significant benefit is not specified and allows for a wide range of interpretation [2]. Yet the more inconcrete is the answer to the question – "who and how should determine the interests of the individual, the family and even the state?" The national doctrine of education in the Russian Federation, which determined the goals of teaching and upbringing, the ways to attain them by means of the state policy regulating the field of education, the target achievements of the development of the educational system for the period up to 2025, approved by the Decree of the Government of the Russian Federation of October 4, 2000 #751, was abrogated by the Decree of the Government of the Russian Federation of March 29, 2014 #245 [7]. The new doctrine has not been developed so far. The RAE Academician A.B. Khutorsky believes that the absence of the national doctrine of education presents a threat to national security and a violation of the right of citizens to quality education. Accordingly, the teacher has to solve the problem of achieving the harmony of interests of the individual, the family, the society and the government on their own, which, however, judging by the officially published results, is the task that exceeds the abilities of the participants of the educational process.  The particular concern about the results of the patriotic upbringing served as a basis for the legislative initiative of the RF President V. V. Putin, who introduced the project of an amendment to the Law of RF "About Education of the Russian Federation" to the State Duma in 2020, regarding the quality of patriotic upbringing [3]. Patriotism, considered by the President of RF V. V. Putin as the only possible idea to unite the nation is "THE FEELING OF LOVE OF THE MOTHERLAND" and the readiness for every sacrifice and heroic deed for the sake of the interests of your Motherland. However, the practicing educators experience shortfalls in efficient methodologies of patriotic upbringing, which should let them bring up citizens, loving their Motherland more than themselves. The article is dedicated to solution to this problem based on the Value-sense paradigm of upbringing educational dynasty of the Kurbatovs [15].

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