THE EFFECT OF ADRENALECTOMY AND ADRENOCORTICAL HORMONES ON THE HAIR GROWTH CYCLE IN THE RABBIT AND RAT

1958 ◽  
Vol 17 (2) ◽  
pp. 167-NP ◽  
Author(s):  
H. J. WHITELEY
Keyword(s):  
Body Weight ◽  
Mitotic Activity ◽  
Hair Growth ◽  
Inhibitory Action ◽  
Growth Cycle ◽  
Bilateral Adrenalectomy ◽  
Hair Regrowth ◽  
Cycle Growth ◽  
The Difference

SUMMARY The effect of cortisone and adrenalectomy on the hair regrowth cycle of the rat and rabbit was investigated. It was found that bilateral adrenalectomy had no effect on the rate of regrowth of hair or on the quality of the coat in the rabbit, but there was decreased mitotic activity of the follicles on the 2nd and 7th day of the regrowth cycle and increased mitotic activity of the epidermis on the 7th day of this cycle. In the rat bilateral adrenalectomy, apart from causing a generalized wave of hair growth, which was not observed in the rabbit, had no effect on the hair regrowth cycle. The local application of hydrocortisone had a slight inhibitory action in the early stages of the cycle, but i.m. injection of cortisone produced profound inhibition. In the rabbit doses of 12·5 mg/kg body weight caused suppression of the usual regrowth cycle, but in some animals the outercoat hairs were unaffected. There was depression of the mitotic activity of the epidermis on the 7th and 10th days of the cycle. If cortisone was given during different stages of the regrowth cycle growth of undercoat hair was much more inhibited than that of the outercoat hair. Similar results were observed in the rat. These results are discussed and it is postulated that the difference in response between the two types of hair might be related to differences in blood supply of the outercoat and undercoat hairs.

Depilatory effects of certain chemicals during the first hair growth cycle in sucking mice

1978 ◽  
Vol 12 (4) ◽  
pp. 185-192 ◽  
Author(s):  
B. A. Panaretto ◽  
D. A. Tunks ◽  
S. Munro
Keyword(s):  
Body Weight ◽  
Hair Growth ◽  
Growth Cycle ◽  
The Body ◽  
Complete Inhibition ◽  
Hair Cycle ◽  
Wool Growth ◽  
Good Agreement

The chemicals were administered, subcutaneously, orally or topically. Generally, the depilation produced in the mice by mimosine or cyclophosphamide differed from that produced by the steroid analogues tested. In the first 2 cases almost completely naked mice were commonly seen, while in the steroid-treated groups the complete inhibition of all hair fibres was rare. This is discussed in relation to the effects of the same compounds on wool growth in sheep. When related to body weight, the doses of cyclophosphamide (62 mg/kg0.75) and dexamethasone (5-10 mg/kg0.75), that depilated mice in our experiments were in good agreement with those reported to inhibit the growth of wool fibres in some sheep. An example of synergism in depilatory effect between dexamethasone and cyclophosphamide is also presented. The time of onset and the initial spread over the body of the 2nd hair cycle in depilated mice was observed.

scholarly journals Diffuse hair loss in women: causes and therapeutic approach

2020 ◽  
pp. 60-63
Author(s):  
O. O. Melnichenko ◽  
A. L. Piruzyan ◽  
I. M. Korsunskaya
Keyword(s):  
Hair Loss ◽  
Hair Growth ◽  
Clinical Effectiveness ◽  
Growth Cycle ◽  
Trigger Factor ◽  
Results Of Treatment ◽  
Trigger Event ◽  
Specialized Care ◽  
Post Menopause

Throughout human history, women have paid great attention to the beauty of their hair, and modern women are no exception. About 63% of young American women use different nutritional supplements to prevent hair loss. Diffuse hair loss is quite common in women and can occur against the background of various events: pregnancy, pre- and post-menopause, chronic diseases, etc. The most common is telogen effluvium (TE), which begins 2-3 months after the trigger event. Usually, TE process stops on its own, but can also become chronic. For many women, pregnancy and associated psycho-emotional stress become the triggering event, and in 75% of cases hair loss can become chronic.In fact, TE is a violation of the hair growth cycle. First of all, it is necessary to exclude the trigger factor from the patient's life and only then to start normalizing the hair growth cycle and improve the quality of hair follicle nutrition. The most effective topical remedy for the treatment of diffuse hair loss is minoxidil. The reasons for its clinical effectiveness have not been fully studied, but it is known that it prolongs the hair growth phase. Unfortunately, after cancellation of the drug, hair loss is often renewed. Avoiding these effects is possible with a comprehensive approach to therapy. Inclusion of additional components in the therapy scheme, such as vitamin and mineral complexes, growth stimulants, specialized care products, allows to maintain and improve the results of treatment with minoxidil. 

Influence of temperature, photoperiod, and food on the speed of development, longevity, fecundity, and other qualities of the Diamond-Back moth Plutella Maculipennis (Curtis) (Lepidoptera: Tineidae).

1955 ◽  
Vol 3 (2) ◽  
pp. 185 ◽  
Author(s):  
AS Atwal
Keyword(s):  
Body Weight ◽  
Dry Matter ◽  
Egg Laying ◽  
Lower Body ◽  
Green Leaves ◽  
Lower Body Weight ◽  
Different Temperatures ◽  
Quality Of Food ◽  
The Difference

Larvae of Plutella maculipennis (Curtis) were reared on food of different qualities at different temperatures and were exposed during their development to different photoperiods. The plants on which the larvae were reared were also exposed to different photoperiods during their development to see whether this influenced the quality of food for the insect. It was found that although caterpillars developed more quickly at 25�C than at l8�C, they weighed less at pupation at 25�C than at l8�C, but the ratio of dry matter to water was the same at both temperatures. Exposure of caterpillars to different photoperiods influenced their speed of development. There was an indication that the influence of light was different at different temperatures. The influence of quality of food was more evident. Larvae reared on white or young green leaves of cabbage developed more quickly than those reared on green but mature or senescing leaves; the slower speed of development was associated with a higher death-rate and a lower body weight combined with a higher water content of the pupae. Irrespective of temperature and the quality of the food, females developed more slowly than males and also had more dry matter and a higher liveweight in the pupal stage. Insects bred at a lower temperature produced more eggs than those at a higher temperature; the difference was thought to be due to a lower body weight in the latter. Photoperiod also influenced fecundity but the effect was not so clear. Caterpillars reared on plants grown in a long photoperiod were more fecund in the adult stage than those reared on plants grown in a short photoperiod, but the difference was not quite significant. Insects reared on white or young green leaves of cabbage laid significantly more eggs than those reared on green but mature leaves. Simarly when larvae were reared on the better quality food they produced more silk, the resulting moths lived longer, and a higher proportion of the males were fertile. The general conclusion is drawn that for normal activities of Plutella a balance of nutrients is required. For the normal activities of the insect body, like healthy development and reproduction, nutrients may be required in certain proportions. If owing to some cause (as probably, with change in season) that proportion is upset, certain abnormalities may appear in the metabolism or form of the insect, such as deformities in wings and shape of body, slower development, reduction or impediment in egg-laying capacity or diapause, etc. In the author's opinion this general conclusion may be a useful hypothesis on which to base further work. In the light of the above observations and observations on other insects, the seasonal activity of Plutella is discussed. It is stated that although apparently its behaviour and activity seem to be nicely adjusted to seasons, showing a beautiful picture of adaptation, yet the recurrent heavy reductions in numbers which this insect and many other species suffer in the field suggest that the adaptations are not as efficient as may at first sight appear.

Over-winter survival in a boreal population of the bank vole, Clethrionomys glareolus

1988 ◽  
Vol 66 (8) ◽  
pp. 1835-1840 ◽  
Author(s):  
A. Fredric Karlsson
Keyword(s):  
Body Weight ◽  
Home Range ◽  
Nutritional Condition ◽  
Clethrionomys Glareolus ◽  
Winter Survival ◽  
Bank Voles ◽  
Before And After ◽  
The Mean ◽  
The Difference

What characteristics enhance the probability of individual bank voles (Clethrionomys glareolus) surviving the winter? Two hypotheses were tested in this paper: (i) over-winter survival is determined by an individual's nutritional condition, such that voles in poor condition succumb disproportionately often, and (ii) over-winter survival is determined by the quality of an individual's home range. The study was performed during two winters near Uppsala, Sweden. Body weight could not be used to predict over-winter survival in males or in females. The mean body weight of males decreased significantly from October through December. Females remaining within one home range throughout the winter and reproducing (P+) were, on average, heavier during all months from October to April than those not recaptured after the onset of breeding (P−), suggesting a difference in age rather than a difference in condition. Rocky areas are preferred as overwintering habitats. Persistent voles used the same rocky microhabitats before and after the onset of breeding. The difference between persistent and nonpersistent voles is interpreted in terms of individual differences in the success of establishment. A difference in micro-habitat use among P+ and P− females suggests a difference in microhabitat optima in different years. The difference between P+ and P− within years suggests a difference in individual status and fewer options for those individuals arriving later.

Letter to the Editor: The Continuing Challenge of Evaluating RSD Impairment and Disability

1998 ◽  
Vol 3 (5) ◽  
pp. 8-10
Author(s):  
Robert L. Knobler ◽  
Charles N. Brooks ◽  
Leon H. Ensalada ◽  
James B. Talmage ◽  
Christopher R. Brigham
Keyword(s):  
Disability Evaluation ◽  
Body Part ◽  
Loss Of Function ◽  
Regulatory Requirements ◽  
Major Cardiac Event ◽  
Clinical Scenarios ◽  
Impairment Score ◽  
Occupational Activities ◽  
The Difference

Abstract The author of the two-part article about evaluating reflex sympathetic dystrophy (RSD) responds to criticisms that a percentage impairment score may not adequately reflect the disability of an individual with RSD. The author highlights the importance of recognizing the difference between impairment and disability in the AMA Guides to the Evaluation of Permanent Impairment (AMA Guides): impairment is the loss, loss of use, or derangement of any body part, system, or function; disability is a decrease in or the loss or absence of the capacity to meet personal, social, or occupational demands or to meet statutory or regulatory requirements because of an impairment. The disparity between impairment and disability can be encountered in diverse clinical scenarios. For example, a person's ability to resume occupational activities following a major cardiac event depends on medical, social, and psychological factors, but nonmedical factors appear to present the greatest impediment and many persons do not resume work despite significant improvements in functional capacity. A key requirement according to the AMA Guides is objective documentation, and the author agrees that when physicians consider the disability evaluation of people, more issues than those relating to the percentage loss of function should be considered. More study of the relationships among impairment, disability, and quality of life in patients with RSD are required.

Evolution of yield and quality of sainfoin (Onobrychis viciifolia Scop.) in the spring growth cycle

Agronomie ◽  
2003 ◽  
Vol 23 (3) ◽  
pp. 193-201 ◽  
Author(s):  
Giorgio Borreani ◽  
Pier Giorgio Peiretti ◽  
Ernesto Tabacco
Keyword(s):  
Growth Cycle ◽  
Onobrychis Viciifolia ◽  
Yield And Quality

COMBINATORIAL POLYNOMIALLY COMPUTABLE CHARACTERISTICS OF SUBSTITUTIONS AND THEIR PROPERTIES

2020 ◽  
Vol 7 (2) ◽  
pp. 34-41
Author(s):  
VLADIMIR NIKONOV ◽  
◽  
ANTON ZOBOV ◽  
Keyword(s):  
Mathematical Expectation ◽  
Point Of View ◽  
Small Range ◽  
Computational Point ◽  
Wide Range ◽  
Bijective Function ◽  
The Difference ◽  
Element Base ◽  
Selection Of

The construction and selection of a suitable bijective function, that is, substitution, is now becoming an important applied task, particularly for building block encryption systems. Many articles have suggested using different approaches to determining the quality of substitution, but most of them are highly computationally complex. The solution of this problem will significantly expand the range of methods for constructing and analyzing scheme in information protection systems. The purpose of research is to find easily measurable characteristics of substitutions, allowing to evaluate their quality, and also measures of the proximity of a particular substitutions to a random one, or its distance from it. For this purpose, several characteristics were proposed in this work: difference and polynomial, and their mathematical expectation was found, as well as variance for the difference characteristic. This allows us to make a conclusion about its quality by comparing the result of calculating the characteristic for a particular substitution with the calculated mathematical expectation. From a computational point of view, the thesises of the article are of exceptional interest due to the simplicity of the algorithm for quantifying the quality of bijective function substitutions. By its nature, the operation of calculating the difference characteristic carries out a simple summation of integer terms in a fixed and small range. Such an operation, both in the modern and in the prospective element base, is embedded in the logic of a wide range of functional elements, especially when implementing computational actions in the optical range, or on other carriers related to the field of nanotechnology.

THE INFLUENCE OF TILLAGE SYSTEMS ON THE GROWTH, DEVELOPMENT AND YIELD OF LONG-FLAX

2020 ◽  
Author(s):  
V. Dumych ◽  
Keyword(s):  
Growth And Development ◽  
Field Experiments ◽  
Conservation Tillage ◽  
Mineral Fertilizers ◽  
Tillage Systems ◽  
Yield And Quality ◽  
Tillage System ◽  
The Difference ◽  
Flax Seeds

The purpose of research: to improve the technology of growing flax in the Western region of Ukraine on the basis of the introduction of systems for minimizing tillage, which will increase the yield of trusts and seeds. Research methods: field, laboratory, visual and comparative calculation method. Research results: Field experiments included the study of three tillage systems (traditional, canning and mulching) and determining their impact on growth and development and yields of trusts and flax seeds. The traditional tillage system included the following operations: plowing with a reversible plow to a depth of 27 cm, cultivation with simultaneous harrowing and pre-sowing tillage. The conservation system is based on deep shelfless loosening of the soil and provided for chiseling to a depth of 40 cm, disking to a depth of 15 cm, cultivation with simultaneous harrowing, pre-sowing tillage. During the implementation of the mulching system, disking to a depth of 15 cm, cultivation with simultaneous harrowing and pre-sowing tillage with a combined unit was carried out. Tillage implements and machines were used to perform tillage operations: disc harrow BDVP-3,6, reversible plow PON-5/4, chisel PCh-3, cultivator KPSP-4, pre-sowing tillage unit LK-4. The SZ-3,6 ASTPA grain seeder was used for sowing long flax of the Kamenyar variety. Simultaneously with the sowing of flax seeds, local application of mineral fertilizers (nitroammophoska 2 c/ha) was carried out. The application of conservation tillage allows to obtain the yield of flax trust at the level of 3,5 t/ha, which is 0,4 t/ha (12.9 %) more than from the area of traditional tillage and 0,7 t/ha (25 %) in comparison with mulching. In the area with canning treatment, the seed yield was the highest and amounted to 0,64 t/ha. The difference between this option and traditional and mulching tillage reaches 0,06 t/ha (10,3 %) and 0.10 t/ha (18.5 %), respectively. Conclusions. Preservation tillage, which is based on shelf-free tillage to a depth of 40 cm and disking to a depth of 15 cm has a positive effect on plant growth and development, yield and quality of flax.

Pengaruh ovaprim, aromatase inhibitor, dan hipofisa terhadap kualitas telur ikan Lele Dumbo (Clarias gariepinus)

2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Erwin A. Aziz ◽  
Ockstan Kalesaran
Keyword(s):  
Survival Rate ◽  
Experimental Design ◽  
Aromatase Inhibitor ◽  
Fish Larvae ◽  
Clarias Gariepinus ◽  
Randomized Design ◽  
Completely Randomized Design ◽  
The Difference ◽  
Hatching Eggs

This study aimed to determine the effect of ovaprim hormone, aromatase inhibitor and pituitary on the quality of the catfish eggs (Clarias gariepinus). Experimental Design used was Completely Randomized Design (CRD) with four treatments, each with three replications. Treatment A: ovaprim; treatment B: Aromatase inhibitors, treatment C: hypophysis and treatment D: Control. The results showed that the difference in treatment gave highly significant effect on fertilization and hatching eggs but no significant effect on the survival rate of larvae. Aromatase inhibitor hormone was the best because it provided highly significant effect on fertilization (92.66%), hatchability of eggs (95%), and surviva rate (81.33%) of fish larvae.   Keywords : Clarias gariepinus. Ovaprim, Aromatase Inhibitor, Hypophysis, egg, larvae

Multivariate micropollutants analysis in marine waters

1995 ◽  
Vol 32 (9-10) ◽  
pp. 341-348
Author(s):  
V. Librando ◽  
G. Magazzù ◽  
A. Puglisi
Keyword(s):  
Multivariate Data Analysis ◽  
Partial Least Squares Regression ◽  
Environmental Chemistry ◽  
Sampling Site ◽  
Principal Component ◽  
Least Squares Regression ◽  
Organic Micropollutants ◽  
Suspended Material ◽  
The Difference

The monitoring of water quality today provides a great quantity of data consisting of the values of the parameters measured as a function of time. In the marine environment, and especially in the suspended material, increasing importance is being given to the presence of organic micropollutants, particularly since some are known to be carcinogenic. As the number of measured parameters increases examining the data and their consequent interpretation becomes more difficult. To overcome such difficulties, numerous chemometric techniques have been introduced in environmental chemistry, such as Multivariate Data Analysis (MVDA), Principal Component Analysis (PCA) and Partial Least Squares Regression (PLSR). The use of the first technique in this work has been applied to the interpretation of the quality of Augusta bay, by measuring the concentration of numerous organic micropollutants, together with the classical water pollution parameters, in different sites and at different times. The MVDA has highlighted the difference between various sampling sites whose data were initially thought to be similar. Furthermore, it has allowed a choice of more significant parameters for future monitoring and more suitable sampling site locations.

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