Formation of specific immunological a-reactivity during pregnancy in sows

2020 ◽  
Vol 1 ◽  
pp. 110-114
Author(s):  
A.V. Agarkov ◽  
A. F. Dmitriev ◽  
A. N. Kvochko ◽  
N.V. Agarkov ◽  
Keyword(s):  
Infectious Agent ◽  
Intrauterine Infection ◽  
Point Of View ◽  
Functional Abilities ◽  
Functional Reserves ◽  
Development Processes ◽  
Adult Organism ◽  
The One ◽  
High Level ◽  
Minimally Invasive Methods

Changes of immunological reactivity to viral and bacterial antigens can cause in-creased susceptibility to infectious diseases. Different levels of this changes in newborn and adult animal organisms should be based on the fetus and newborn reactivity, first coming into contact with the antigen after birth, whereas the adult organism already has partial sensitization. Chronic vectors of pathological agents in animals and their in-fluence on the spread of infectious process is a persisting problem of modern veterinary medicine. The ability to use vaccination in newborns is limited by the presence of maternal antibodies that have immunosuppres-sive effects. High level of functional abilities of preg-nant organism is important in prevention of intrauterine infection. Infection in the prena-tal period of development affects fetal growth and development processes on the one hand, and on the other - isoimmuniza-tion of the maternal organism with fetal anti-gens occurs, accompanied by increased sen-sitivity of the organism with predominant manifestation of cellular phenomena, in the absence of increased synthesis of antibodies. Given the high importance of the functional reserves of the newborn organism, the intra-uterine development and completeness of the placental barrier are important. Detection of the transportation of infectious agent in inac-tive phase during pregnancy of different gestational period should be considered from the point of view of avidity and seropositivi-ty of pregnant animals. The high variety of clinical manifesta-tions of intrauterine infection requires the development of minimally invasive methods of antenatal and intranatal prediction, which allow at the stage of pregnancy and/or child-birth to assess the presence of an agent in a very small amount as the risk of the future development of infectious disease of the fetus and newborn, or complications of the early neonatal period.

scholarly journals Specific immunological areactivity formation during gestation period in pregnant sows

2020 ◽  
Vol 210 ◽  
pp. 06002
Author(s):  
Alexander Agarkov ◽  
Anatoly Dmitriev ◽  
Andrey Kvochko ◽  
Elena Grudeva ◽  
Nikolay Agarkov ◽  
...  
Keyword(s):  
Intrauterine Infection ◽  
The Body ◽  
Functional Reserves ◽  
Increased Sensitivity ◽  
The One ◽  
High Level ◽  
Chronic Carrier ◽  
Fetal Antigens ◽  
Different Levels ◽  
Increased Susceptibility

Changes in immunological reactivity to viral and bacterial antigens may cause increased susceptibility to infectious diseases. Different levels of this condition in newborn and adult animal organisms should be based on the fact that the fetus and newborn after birth first comes into contact with the antigen, while the adult body already has partial sensitization. Chronic carrier of pathogens in animals and their influence on the spread of the infectious process is an urgent problem of modern veterinary medicine. The possibility of vaccination in newborns is limited by the presence of maternal antibodies that have an immunosuppressive effect. A high level of functional reserves of the pregnant body is important in the prevention of intrauterine infection. On the one hand, infection in the prenatal period of development affects the processes of growth and development of the fetus, on the other hand, during this period, the mother's body is isoimmunized by fetal antigens, accompanied by increased sensitivity of the body with the predominant manifestation of cellular phenomena in the absence of enhanced antibody synthesis.

ANALISIS TERHADAP SOAL PENILAIAN AKHIR SEMESTER TINGKAT SD/MI DALAM PERSPEKTIF HIGH ORDER THINK SKILLS

2020 ◽  
Vol 12 (33) ◽  
Author(s):  
Yudha Andana Prawira ◽  
Titim Kurnia
Keyword(s):  
Critical Thinking ◽  
Critical Reflection ◽  
Descriptive Analysis ◽  
High Order ◽  
Point Of View ◽  
The Other ◽  
National Education ◽  
The One ◽  
High Level ◽  
High Level Thinking

The National Education World is currently trying to improve the ability of its students to think critically and creatively. One of these efforts has been pursued through evaluations that also lead to critical reflection. This research is a descriptive analysis of the final semester evaluation questions that are examined from the point of view of high-level thinking [HOTS]. The reference to the HOTS criteria is that the researcher refers to the opinions of King and his friends. From the manuscript data, the issues examined are samples from the Bandung area. The results of the analysis show that 10 out of 15 HOTS ranges proposed by King are already included in the scripts made by the teachers. On the one hand, it shows the teacher's creativity in compiling questions. On the other hand, all these questions do not refer to the HOTS criteria as planned. Therefore, there is a need to increase teachers' skills in compiling scripts as HOTS. This increase can be done through teacher training.Keywords: Evaluation, HOTS, critical thinking and creativity thingking

scholarly journals Digital medicine: risks for implementing innovations in the healthcare sector

2020 ◽  
pp. 84-94
Author(s):  
Evgeniya Chernyh
Keyword(s):  
Social Relations ◽  
Scientific Evidence ◽  
Point Of View ◽  
Fundamental Rights ◽  
Healthcare Sector ◽  
Real Problem ◽  
Digital Medicine ◽  
The One ◽  
Fundamental Rights And Freedoms ◽  
High Level

The population of many developing countries, including Russia, is characterized by a high level of resistance and immunity to innovations affecting their fundamental rights and freedoms. Opportunities for the introduction and application of digital medicine are perceived skeptically, on the one hand from the point of view of its fantasticism, on the other — its riskiness. A significant part of the ideas about it is based on an existential and ethical threat, which currently has virtually no scientific evidence or prerequisites. while the real problem is that the modern legal reality is not ready for rapid technological progress. legislation is not able to properly regulate social relations, the existence of which yesterday seemed unrealistic, and today they are rapidly integrated into our lives. only the formation of a comprehensive unified view of the essence and content of digital medicine can help solve this issue. Whereas this becomes possible only after assessing all the existing risks of its legal implementation, which is what this article is devoted to.

DYNAMICS OF THE QUALITIES IMPORTANT FOR LEARNING DURING PROFESSIONAL DEVELOPMENT OF OFFICER CADETS

2019 ◽  
pp. 50-59
Author(s):  
V. Bosnyk
Keyword(s):  
Professional Training ◽  
Evaluation Method ◽  
Point Of View ◽  
Learning Success ◽  
Intellectual Abilities ◽  
Expert Evaluation Method ◽  
The One ◽  
High Level ◽  
Communicative Abilities ◽  
Academic Year

The article examines officer cadets’ activities in two aspects from the point of view of the system-genetic approach. On the one hand, the officer cadets receive professional training at military university, and on the other, they simultaneously serve in the army. The used expert evaluation method helps the author to determine the cadets’ qualities united into four groups: volitional, motivational, cognitive and communicative abilities. It has been established that some personally important qualities are being changed during cadets’ training, namely, responsibility, diligence, activity, purposefulness and communicative abilities. The analysed dynamics of average values of the qualities important for cadets’ training indicates that volitional psychological qualities increase steadily from the first to the third academic year. During the fourth academic year, volitional qualities decrease, generally, or remain at the same level. The cadets’ motivation gradually decreases during education. The indicators of communicative and organizational abilities remain at a stable high level during university training, and intellectual abilities are even higher than average. Thus, from the academic year to the academic year, the number of psychological qualities influencing directly cadets’ successful training increases. The volitional component becomes more important at the senior courses, but communicative abilities decreases. Of all the qualities important for learning studied at the research, only intellectual abilities are statistically significantly correlate with learning success during all academic years.

scholarly journals Quantitative Analysis of Tourism Potential in the Czech Republic

2017 ◽  
Vol 65 (3) ◽  
pp. 1085-1098
Author(s):  
Jiří Vystoupil ◽  
Martin Šauer ◽  
Ondřej Repík
Keyword(s):  
Czech Republic ◽  
Quantitative Analysis ◽  
Point Of View ◽  
Practical Implementation ◽  
Public Infrastructure ◽  
Local Conditions ◽  
The Czech Republic ◽  
Tourism Potential ◽  
The One ◽  
High Level

On the one hand, tourism is a significantly spatially differentiated socio‑economic phenomenon, bound to the attractiveness of local conditions. On the other hand, it is a sectional phenomenon which requires a high level of coordination and cooperation of all tourism stakeholders. This is the background for the practical implementation of tourism policy. The state’s conceptual activity and its institutions are irreplaceable in this respect. From this point of view, a prerequisite for quality economic‑political decisions of the existence of materials and methods, which these features respect, is necessary. One of these prerequisites is a quantitative analysis of tourism potential in the Czech Republic, which should be a basis for direct and targeted state’s interventions into the improvement of public infrastructure of tourism in the area. The main purpose of the quantitative analysis of tourism potential is to objectively measure the tourism potential, i.e., to set the criteria for the evaluation of its national, regional, and local importance and consequently, conduct a comparative analysis of the tourism areas and centers of importance according to the key types of tourism. Finally, on the basis of the processed factual, statistical and cartographic information to propose functionally spatial delimitation of tourism potential.

scholarly journals Immunological aspects of tuberculosis pathogenesis

2019 ◽  
Vol 91 (11) ◽  
pp. 90-97
Author(s):  
V Ja Gergert ◽  
M M Averbakh ◽  
A E Ergeshov
Keyword(s):  
Human Body ◽  
Clinical Manifestations ◽  
Infectious Agent ◽  
Point Of View ◽  
The Body ◽  
Natural Resistance ◽  
Individual Response ◽  
Foreign Agent ◽  
The Individual ◽  
High Level

The morphological aspects of TB pathogenesis are well described in the publications. Much is also known about the main stages of development and formation of specific adaptive immunity. However, from our point of view, not enough attention is being paid to the involvement of the immune system in the pathogenesis of clinically relevant TB abnormalities, as well as various forms of the disease. Nevertheless, there is no doubt that the variety of clinical manifestations of any disease associated with the penetration of a foreign agent into the body, and Mycobacterium tuberculosis (MTB) in particular, is due to the collective interaction of the infectious agent and the individual response of the macroorganism to this infectious agent. The mosaic of such interactions usually imposes its own adjustments on the development of different forms of the process, its speed and direction, as well as the outcomes. Certainly, the response of a macroorganism to MTB is an integral part of pathogenesis and consists of many general components including the responses associated with the mechanisms of natural and acquired immunity. Intensity of these reactions depends on the characteristics of an agent (MTB) and a macroorganism. For the development of TB disease, massiveness of TB infection, dose and duration of MTB exposure to the human body, as well as virulence of MTB and the level of body's protection during the exposure play a very important role. TB pathogenesis is somewhat different in primary MTB infection and re - infection. With primary infection, 88-90% of individuals do not have clinical manifestations, and only the tuberculin skin test conversion signals the onset of infection. In some cases, without any use of anti-TB drugs limited abnormalities may result in spontaneous cure with the minimal residual changes in the lungs, intrathoracic lymph nodes and tissues of other organs, often in the form of calcifications and limited areas of fibrosis in more advanced cases. Only 10-12% of newly infected individuals develop TB with severe clinical manifestations requiring TB therapy. The absence of clinical manifestations of primary TB infection can be explained by a high level of natural resistance of the human body to tuberculosis, and sometimes can be an effect of acquired protection due to BCG vaccination. This review attempts to discuss the role of immune mechanisms in the pathogenesis both at the beginning of disease development, and in the process of its various manifestations. Issues of genetically determined resistance or susceptibility to TB are not being covered in detail in this manuscript.

scholarly journals Sport Events Customers’ Behavior in the Light of Hedonic Consumption

2020 ◽  
Vol 12 (3) ◽  
pp. 26
Author(s):  
Daniel Adrian Gârdan ◽  
Iuliana Petronela Gârdan ◽  
Mihai Andronie ◽  
Ionel Dumitru
Keyword(s):  
Large Mass ◽  
Consumer Involvement ◽  
Point Of View ◽  
Special Role ◽  
Sport Tourism ◽  
Emotional Involvement ◽  
Hedonic Consumption ◽  
Sport Events ◽  
The One ◽  
High Level

Consumption of sport events has raised the specialists’ interest since it has become a global phenomenon, accessible to a large mass of consumers. At the same time, this consumption generates implications from an economic, social, and cultural point of view, in the countries/locations where various sport events have been organized, through the development of cultural and sport tourism. Sport event consumption belongs to the category of consumption acts that presume total implication apart from individuals and accordingly, their emotional involvement. This involvement is correlated on the one hand with the typology and the nature of needs and consumption motives underlying this consumption, and on the other hand with the more and more intensive promotion of these events and the easier participation access of consumers. Consumer involvement is a multidimensional construct, so the idea of an “involvement profile” is more appropriate to describe how the consumer relates to such products or services. The purpose of our paper is to clarify whether involvement within consumption for sport events customers is determining a specific behavior for the hedonic type of consumption also related to other categories of products or services. The consumption of sport events represents mainly a hedonic type of consumption correlated with a high level of emotional involvement during the consumption process, an involvement developed against the backdrop of the special role, and specific meaning that sport events can have at the level of individuals’ perception.

scholarly journals El Tratado de Vitruvio ilustrado : los dibujos de la basílica = The Vitruvian treaty illustrated. The basilica drawings

2014 ◽  
pp. 95
Author(s):  
Juan Calduch Cervera
Keyword(s):  
Direct Observation ◽  
El Paso ◽  
Written Language ◽  
Point Of View ◽  
The Real ◽  
Complex Information ◽  
The One ◽  
High Level ◽  
Graphic Elements ◽  
Real Building

Los dibujos del levantamiento de un edificio suponen, ya, un alto grado de abstracción o conceptualización que consiste en traducir en elementos gráficos la información aportada por la imagen sensible. Cuando el paso entre la visión del edificio a  su imagen dibujada está mediatizado por el lenguaje hablado o escrito, el dibujo es más elocuente del pensamiento de quien lo traza que del autor que lo describe o la realidad a la que se remite. Los dibujos de la basílica antigua elaborados a partir del tratado de Vitruvio por Fra Giocondo (1511), Cesariano (1523), Palladio (1556, 1570), Perrault (1673) Galiani (1758) y Ortíz y Sanz (1778), así como sus diferencias, más que la idea del tratadista romano, nos permiten conocer los intereses que movían a sus respectivos autores. Abstract Any drawing representing a building implies by itself a high level of abstraction and conceptualization, because it supposes the translation into graphic elements of all the complex information kept by our senses. This situation becomes even more extreme when this process does not begin from the direct observation of the building, but from a spoken or written language. For this reason, the drawing of a building which has been described in a narration, talks on fact more about its author’s point of view, than about the one who is describing it, or even more than the real building itself. The drawings of the basilicas using Vitruvius’ treatise as a reference, and made by Fra Giocondo (1511),  Cesariano (1523), Palladio (1556, 1570), Perrault (1673),  Galiani (1758) and Ortiz y Sanz (1778), more than talking about roman’s author ideas, allow us to know the thoughts of their respective authors.

Looking for an emergency door

2016 ◽  
Vol 36 (1/2) ◽  
pp. 102-118 ◽  
Author(s):  
Paolo Rossi
Keyword(s):  
Social Services ◽  
Social Assistance ◽  
Point Of View ◽  
Alternative View ◽  
Dynamic Factor ◽  
Content Type ◽  
Professional Discretion ◽  
The One ◽  
Definition Of ◽  
High Level

Purpose – The paper investigates the role of information asymmetries and sensegiving processes of citizens claiming for social services. The purpose of this paper is to highlight the relevance of applicants’ agency, since it has been generally neglected in the analysis of social services provision. On the contrary, the paper proposes an alternative view, considering applicants as actors who are able to develop dialectic strategies for claiming specific forms of social assistance. Design/methodology/approach – The paper is based on a qualitative research, conducted following an inductive approach. The data have been collected in three different Italian municipalities, where the researcher has been the opportunity to perform a period of observation of the interviews between the social workers of the local social services department and the citizens applying for social assistance. Findings – The findings of the research point out that informational asymmetries play an ambivalent role in the definition of applicant’s strategies, since they represent an ambivalent and dynamic factor, rather than a mere source of disadvantage for the user. From this viewpoint, the citizens’ possibilities to access to social assistance are shaped by both institutional and dialectic factors: on the one hand, access to social assistance relies on specific criteria of eligibility (institutionally defined), but on the other hand the access is the outcome of situated sensegiving processes, performed by both the applicants and the gatekeepers of social services during their encounters. Research limitations/implications – The research is based on the analysis of a small number of cases, within a context that is characterized by a high level of organizational and professional discretion in the regulation of the provision of social assistance. Practical implications – The findings of the research urge policy maker to re-consider applicants as strategic actors and opens the space for the development of new options of regulation of the delivery of social services. Social implications – The paper suggests to consider the applicants for social services as people who, although in a condition of need, are capable to identify specific forms of assistance. From this point of view, informational asymmetries are not be considered as a stigmatic issue, but as a space which calls for further and less superficial investigation. Originality/value – The paper challenges some of the most taken-for-granted theoretical assumptions in the analysis of the regulation of the access to social assistance. First, it proposes a dynamic interpretation of the notion of informational asymmetries, considering them as a space for action, rather than a binding factor; second, it emphasizes the relevance of user’s agency in the access to welfare services, that is generally neglected since most analyses focus on professional discretion disregarding the hypothesis of the user as a strategic actor.

Understanding functional illiteracy from a policy, adult education, and cognition point of view: Towards a joint referent framework

2019 ◽  
Vol 30 (2) ◽  
pp. 109-122
Author(s):  
Aleksandar Bulajić ◽  
Miomir Despotović ◽  
Thomas Lachmann
Keyword(s):  
Adult Education ◽  
Operational Definition ◽  
Literacy Skills ◽  
Point Of View ◽  
Industrialized Countries ◽  
Functional Illiteracy ◽  
Scale Levels ◽  
Components Of Reading ◽  
The One ◽  
Definition Of

Abstract. The article discusses the emergence of a functional literacy construct and the rediscovery of illiteracy in industrialized countries during the second half of the 20th century. It offers a short explanation of how the construct evolved over time. In addition, it explores how functional (il)literacy is conceived differently by research discourses of cognitive and neural studies, on the one hand, and by prescriptive and normative international policy documents and adult education, on the other hand. Furthermore, it analyses how literacy skills surveys such as the Level One Study (leo.) or the PIAAC may help to bridge the gap between cognitive and more practical and educational approaches to literacy, the goal being to place the functional illiteracy (FI) construct within its existing scale levels. It also sheds more light on the way in which FI can be perceived in terms of different cognitive processes and underlying components of reading. By building on the previous work of other authors and previous definitions, the article brings together different views of FI and offers a perspective for a needed operational definition of the concept, which would be an appropriate reference point for future educational, political, and scientific utilization.

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