In the event of industrial revolution 4.0, commonly known as the "Age of Disruption", several challenges and opportunities arise and affect various aspects of human life. With no exception in the field of science which gave birth to a new paradigm in the realm of philosophy of science. The Faculty of Ushuluddin as the core of the University of Darussalam Gontor Ponorogo is also in need of evaluation and improvement in order to answer the challenges and to take advantage of these opportunities. A firm construction of the Faculty’s epistemology requires a massive revitalization in many aspects. In this paper, the author describes the aspects that need special attention by using Gavin Moodie's perspective to produce a comprehensive map for the aspects that support the continuity of higher education in the age of disruption. Revitalization by the Faculty of Ushuluddin would include the aspects of learning system, educational components, students, human resources, and literacy. The learning system needs to utilize a wide range of supporting digital media that the students are familiar with. The educational components which comprise the facility and infrastructure to support learning activities from classrooms, classrooms’ layouts, dormitories, equipment, and management in the faculty also receives very intense attention in accordance with the times. Students need to be equipped with 10 basic skills needed by the world and society today, these skills include the ability of metacognition, which is the ability of advance thinking. To achieve the previous profile, it is necessary to provide, guide and develop educators (HR) and to be supported by a new literacy movement that includes digital, technological, and human literacy. All of these revitalization efforts are still based on the philosophy of life of the Darussalam Gontor Islamic Boarding School, it is “the preservation of good traditions and adoption of a better innovation.