scholarly journals Fetal transverse cerebellar diameter measurement in intrauterine growth restriction: a more accurate parameter for gestational age assessment at term

2019 ◽  
Vol 8 (11) ◽  
pp. 4391
Author(s):  
Saroj Mourya ◽  
Harish Kumar Mourya ◽  
Vimla Jain ◽  
Manoj Verma
Keyword(s):  
Pregnant Women ◽  
Gestational Age ◽  
Accurate Estimation ◽  
Growth Disorders ◽  
Third Trimester ◽  
Singleton Pregnancy ◽  
Age Assessment ◽  
Medical College ◽  
Significant Difference ◽  
Reliable Parameter

Background: Assessment of fetal gestational age (GA) is an essential part of obstetric USG. Accurate knowledge of fetal GA is important to facilitate the best possible prenatal care and successful pregnancy outcome.  For the estimation of GA the commonly used parameters in third trimester are:- BPD, HC, AC and FL. As all these parameters are affected by fetal growth disorders and fetal position. TCD can be used as another parameter for the estimation of GA in growth restricted fetuses.Methods: This study was conducted at Mahila Chikitsalaya Sanganeri Gate; SMS Medical College Jaipur from July 2005 to September 2006. A total of 80 pregnant women in third trimester with singleton pregnancy including 40 pregnant women with known cases of IUGR and 40 AGA fetuses were studied for TCD measure.Results: Correlation coefficient between TCD and gestational age was highly significant and no significant difference was found in TCD of AGA and IUGR fetuses.Conclusions: TCD measurement can be used as more reliable parameter for accurate estimation of gestational age in IUGR fetuses in third trimester.

scholarly journals Chemotherapy for breast cancer during pregnancy induces vascular alterations and impaired development of placental villi: a preliminary histopathological study.

2019 ◽  
Author(s):  
Alessandro Del Gobbo ◽  
Giovanna Scarfone ◽  
Fedro Alessandro Peccatori ◽  
Antonella Villa ◽  
Wally Ossola ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Birth Weight ◽  
Pregnant Women ◽  
Gestational Age ◽  
First Trimester ◽  
Histopathological Study ◽  
Third Trimester ◽  
Significant Difference ◽  
Placental Villi ◽  
Fetal Malformations

Abstract Breast cancer is diagnosed in approximately 1/3000 pregnant women. Chemotherapy may be administered after the first trimester, with improved maternal outcome and relatively few pregnancy and offspring complications. Nonetheless, no information about the effects of different chemotherapy regimens on placenta architecture and vasculature are available. Methods To evaluate histological alterations in placentas of women affected by breast cancer and treated with chemotherapy during pregnancy, we retrospectively analyzed 23 placentas of patients affected by breast cancer and treated with chemotherapy during pregnancy and 23 control placentas of women without breast cancer and with physiological pregnancies of the same gestational age. Results All the patients had breast ductal infiltrating carcinoma, 19 of 23 cases had a G3 cancer. All patients were treated with 2-6 cycles of chemotherapy starting after 16 weeks of gestation, with different protocols. No hypertensive complications and no pre-eclampsia episodes were observed; birth weight was consistent with gestational age in all babies in both group with no uneventful outcomes and no perinatal mortality or fetal malformations. Twenty out of 23 cases (86%) showed hypoxia-induced villous alterations, including increased syncytial knotting (Tenney-Parker changes), perivillar fibrin deposits, distal villous hypoplasia or accelerated maturation and focal villous chorangiosis. These alterations were found in 19 out of 23 controls (83%), with no statistically significant difference between the two groups. Conclusions These results shows that chemotherapy in the second and third trimester of pregnancy may lead to non-specific alterations in placental vasculature and morphology.

scholarly journals Maternal Serum Levels of Alpha Tumour Necrotic Factor, Interleukin 10, Interleukin 6 and Interleukin 4 in Malaria Infected Pregnant Women Based on Their Gestational Age in Southeast, Nigeria

2020 ◽  
pp. 64-70
Author(s):  
Obeagu, Emmanuel Ifeanyi ◽  
Esimai, Bessie Nonyelum ◽  
Ekelozie, Ifeoma Stella ◽  
Asogwa Eucharia Ijego ◽  
Amaeze Augustine Amaeze ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Gestational Age ◽  
First Trimester ◽  
Interleukin 10 ◽  
Interleukin 4 ◽  
Second Trimester ◽  
Third Trimester ◽  
Tnf Α ◽  
Significant Difference ◽  
Tumour Necrotic Factor

Malaria has been reported as a condition caused by infestation with Plasmodium parasite species, is a major public health problem globally especially in developing countries like Nigeria. This study was carried out in Federal Medical Centre Umuahia in Abia State, Nigeria. A study was done to determine the maternal serumlevels of alpha tumour necrotic factor, interleukin 10, interleukin 6and interleukin 4 in malaria infected pregnant women based on their gestational age in Southeast, Nigeria. A total of 150 subjects between the ages of 18-45 years were recruited for the study comprising of fifty (50) subjects each of the 3 trimesters. Commercial ELISA Kit by MELSIN Medical Co Limited was used to measure all the cytokines. The results of Table 1 showed no significant difference of TNF-α (p=0.346), IL-10 (p=0.059), IL-6 (p=0.811) and IL-4 (p=0.257) of malaria infected pregnant women at first trimester and second trimester respectively. The results of Table 2 showed no significant difference of TNF-α (p=0.642), IL-10 (p=0.678), IL-6 (p=0.551) and IL-4 (p=0.280) of malaria infected pregnant women at first trimester and third trimester respectively. The results of Table 2 showed no significant difference of TNF-α (p=0.062), IL-10 (p=0.016), IL-6 (p=0.352) and IL-4 (p=0.914) of malaria infected pregnant women at first trimester and third trimester respectively. The study showed no changes in the cytokines studied among the malaria infected pregnant women based on gestational ages except when IL-10 was compared between the subjects on second trimester and third trimester. This study shows that malaria infection does not changes these cytokines in pregnant women based on gestational ages except the il-10 when compared at second trimester and third trimester but changes when compared at other trimesters.

Prevalensi Bakteriuria Asimtomatik pada Ibu Hamil di Daerah Pesisir

MEDULA ◽  
2019 ◽  
Vol 6 (1) ◽  
Author(s):  
Juminten Saimin ◽  
Ashaeryanto Ashaeryanto ◽  
Asmarani Asmarani
Keyword(s):  
Antenatal Care ◽  
Pregnant Women ◽  
Gestational Age ◽  
Coastal Area ◽  
Asymptomatic Bacteriuria ◽  
Third Trimester ◽  
Chi Square ◽  
Significant Difference ◽  
Chi Square Test ◽  
Tract Infections

ABSTRACTBackground: Pregnant women more often experience urinary tract infections, especially asymptomatic bacteriuria. Asymptomatic bacteriuria in pregnant women increases the risk of preterm labor, low birth weight, and pyelonephritis.Objectives: This study aimed to determine the prevalence of asymptomatic bacteriuria in pregnant women in coastal areas.Method:This study design was analytic observational with cross sectional method. The research was carried out in the coastal area of Kendari city. The population was pregnant women who performed antenatal care in the working area of Puskesmas Mata, Puskesmas Nambo and Puskesmas Abeli in May-October 2016. Sampling was simple random sampling. Data analysis used Chi square test with significance level <0.05.Result:In this study 268 urine samples were obtained from respondents who performed antenatal care in the coastal area of Kendari City. The highest respondents aged 26-30 years old (42.1%), high school education (49.6%), third trimester (55, 6%) and the entrepreneurial husband (41.8%). Examination of bacteriuria showed positive test with nitrite and leukocytes (24.6%) and positive nitrite and/or leukocytes (30.9%). The highest prevalence of bacteriuria occurs in the third trimester (36.9%). Chi-square test showed a significant difference in the prevalence of bacteriuria according to gestational age (p <0.00).Conclusion: The prevalence of asymptomatic bacteriuria in pregnant women in coastal areas was 30.9%. The highest prevalence occurs in third trimester of pregnancy.Key words :asymptomatic bacteriuria, gestational age, pregnant women

scholarly journals Platelet Count In Preeclampsia

2013 ◽  
Vol 18 (2) ◽  
pp. 24-26 ◽  
Author(s):  
Razia Sultana ◽  
SM Fazlul Karim ◽  
Farhana Atia ◽  
Shahnila Ferdousi ◽  
Selina Ahmed
Keyword(s):  
Platelet Count ◽  
Pregnant Women ◽  
Case Control Study ◽  
Case Control ◽  
Third Trimester ◽  
Medical College ◽  
Significant Difference ◽  
The Mean ◽  
The Relationship ◽  
Control Study

Preeclampsia is one of the most leading causes of maternal mortality in developing countries like Bangladesh. Several studies have demonstrated the relationship between platelets count and preeclampsia. The aim of the study was to assess the association of platelets count with preeclampsia. A case control study was conducted in the Department of Biochemistry, Dhaka Medical College, Dhaka from July 2010 to June 2011. A total number of 100 pregnant women in third trimester of pregnancy attending in Obstetrics & Gynaecology Department of Dhaka Medical Hospital were selected as study subjects. Among them 50 diagnosed cases of preeclampsia were selected as cases and 50 normal healthy pregnant women as controls. Platelet count was measured in all study subjects. The mean platelet count in cases and controls were 1,44,260±96,472 and 1,98,100±51,219 respectively. The present study showed significant difference of mean platelet count between cases and controls. The study revealed that low platelets count is associated with preeclampsias. DOI: http://dx.doi.org/10.3329/jdnmch.v18i2.16018 J. Dhaka National Med. Coll. Hos. 2012; 18 (02): 24-26

scholarly journals Serum C reactive Protein in Preeclamptic Women

2014 ◽  
Vol 31 (4) ◽  
pp. 194-198
Author(s):  
S Sultana ◽  
SR Dabee ◽  
S Akter ◽  
MR Khatun ◽  
P Akhter
Keyword(s):  
Pregnant Women ◽  
Early Stage ◽  
Control Group ◽  
Case Group ◽  
C Reactive Protein ◽  
Third Trimester ◽  
College Hospital ◽  
Medical College ◽  
Reactive Protein ◽  
Significant Difference

The incidence of preeclampsia is high in the developing countries. Since this condition is preventable if detected and treated at an early stage, it is essential to diagnose the disease at an early stage, and to institute proper medical care on time. The present study carried out in the Department of Obstetrics and Gynaecology, BIRDEM, and Dhaka Medical College Hospital during January 2009 and June 2010, was aimed to find out concentration of serum C reactive protein (CRP) in preeclamptic women. The study included 60 pregnant women; 30 normal (control) and 30 preeclamptic (case) pregnant women in their third trimester. Estimation of CRP was done by immunoprecipitation assay turbulometry method for both groups. The mean (±SD) age was 23.23±4.58 (control) and 23.90±3.20 (case) years (no significant difference). However, BMI, SBP and DBP were significantly (P<0.001) high in case compared to control group (BMI: 23.37±1.47 and 21.81±1.45 kg/m2; SBP: 148.33±13.41 and 108.00±7.14 mmHg; DBP: 106.67±6.99 and 69.67±5.56 mmHg). C reactive protein concentration (mg/dl) was significantly higher (P<0.001) in case group (10.57±6.71) compared to control group (0.63±0.49). In control and case group, respectively, CRP was normal (£0.8 mg/dl) in 25 (83.3%) and 2 (6.7%), and raised (>0.8 mg/dl) in 5 (16.7%) and 28 (93.3) (P<0.001). This study shows that maternal CRP concentration tends to be significantly high in women with preeclampsia. DOI: http://dx.doi.org/10.3329/jbcps.v31i4.21003 J Bangladesh Coll Phys Surg 2013; 31: 194-198

The sFlt-1 to PlGF Ratio in Pregnant Women with Rheumatoid Arthritis: Impact of Disease Activity and Sulfasalazine Use

Rheumatology ◽  
2021 ◽  
Author(s):  
Rugina I Neuman ◽  
Hieronymus T W Smeele ◽  
A H Jan Danser ◽  
Radboud J E M Dolhain ◽  
Willy Visser
Keyword(s):  
Rheumatoid Arthritis ◽  
Cohort Study ◽  
Disease Activity ◽  
Pregnant Women ◽  
Gestational Age ◽  
Third Trimester ◽  
Low Disease Activity ◽  
The Third ◽  
Observational Prospective Cohort Study ◽  
Plgf Ratio

Abstract Objectives An elevated sFlt-1/PlGF-ratio has been validated as a significant predictor of preeclampsia, but has not been established in women with rheumatoid arthritis (RA). We explored whether the sFlt-1/PlGF-ratio could be altered due to disease activity in RA, and could be applied in this population to predict preeclampsia. Since sulfasalazine has been suggested to improve the angiogenic imbalance in preeclampsia, we also aimed to examine whether sulfasalazine could affect sFlt-1 or PlGF levels. Methods Making use of a nationwide, observational, prospective cohort study on pregnant women with RA, sFlt-1 and PlGF were measured in the third trimester. A total of 221 women, aged 21–42 years, were included, with a median gestational age of 30 + 3 weeks. Results No differences in sFlt-1 or PlGF were observed between women with high, intermediate or low disease activity (p= 0.07 and p= 0.41), whereas sFlt-1 and PlGF did not correlate with DAS28-CRP score (r=-0.01 and r=-0.05, respectively). Four (2%) women with a sFlt-1/PlGF-ratio ≤38 developed preeclampsia in comparison to three (43%) women with a ratio &gt; 38, corresponding to a negative predictive value of 98.1%. Sulfasalazine users (n = 57) did not show altered levels of sFlt-1 or PlGF in comparison to non-sulfasalazine users (n = 164, p= 0.91 and p= 0.11). Conclusion Our study shows that in pregnant women with RA, the sFlt-1/PlGF-ratio is not altered due to disease activity and a cut-off ≤38 can be used to exclude preeclampsia. Additionally, sulfasalazine use did not affect sFlt-1 or PlGF levels in this population.

scholarly journals Estimation of gestational age using foetal kidney length during second and third trimester in south Indian population

Biomedicine ◽  
2021 ◽  
Vol 40 (4) ◽  
pp. 436-441
Author(s):  
Kalpana Ramachandran ◽  
Arunthathy Gnaneshwar ◽  
Robert Dinesh Kumar ◽  
Parvathavarthine CR ◽  
Sri Santhana Krishnan V
Keyword(s):  
Gestational Age ◽  
Tertiary Care ◽  
Abdominal Circumference ◽  
South Indian Population ◽  
Strong Positive Correlation ◽  
Third Trimester ◽  
Age Assessment ◽  
South Indian ◽  
Kidney Length ◽  
Foetal Kidney

Introduction and Aim: Gestational age assessment in women with indeterminate last menstrual period has always remained an enigma. Though multiple parameters have been found useful in providing an indirect age assessment, various studies have now shown that the ultrasonographic measurement of foetal kidney length during the second and third trimester of pregnancy is a viable alternative in foetal age assessment. Methods: This prospective study was conducted among the antenatal women with singleton uncomplicated pregnancy during 18 to 40 weeks of gestation attending the outpatient department for routine ultrasound foetal biometry in a tertiary care referral institution in South India, during January 2019 to June 2019. A total of hundred and thirty-five antenatal mothers were included in this study. Data entry was done in Microsoft Excel and data analysis was done using Statistical Package for Social Sciences (SPSS). Results: There was a strong positive correlation between GA and MKL. Regression model (Model 1) for Mean kidney length showed significant correlation and regression models (Model 2) for MKL and routine foetal biometric parameters like biparietal diameter, femur length and abdominal circumference were found to be significantly correlated. Conclusion: Mean foetal kidney length can alone predict gestational age and by combining it with the other biometric indices to give a better estimation of gestational age.

The effect of ear acupressure medicine at the “Shen Men” point on the nausea and vomiting during pregnancy

2021 ◽  
Vol 15 (5) ◽  
pp. 1774-1779
Author(s):  
Sanaz Nehbandani ◽  
Hajar Salehi ◽  
Khadije Rezaie Keikhaie ◽  
Hossein Rashki Ghalenow ◽  
Fatemeh Mirzaie ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Gestational Age ◽  
Intervention Group ◽  
Nausea And Vomiting ◽  
Control Group ◽  
Health Clinics ◽  
Significant Difference ◽  
Quasi Experimental ◽  
The Mean ◽  
The Difference

Introduction & Objective: Nausea and vomiting during pregnancy is one of the most common gastrointestinal disorders that more than 85% of pregnant women experience. However, controlling and treating this complication is still one of the most important issues in antenatal care. Therefore, the aim of this study was to investigate the effect of ear acupressure at Shen Men point on relieving nausea, vomiting and retching during pregnancy. Materials and Methods: In this quasi-experimental study, 100 pregnant women with a gestational age of less than 16 weeks attending the health clinics of Zabol city during 2019-2020 were studied in two control and intervention groups (n = 50 in each group). The samples in the intervention group were trained to apply pressure on their ears’ Shen Men point with the thumb for three minutes three times a day (morning, noon, and night), for a duration of one month. At the end of second and fourth weeks, the data were collected using the Rhodes index form and then, were analyzed by SPSS software version 22. Results: According to the results, there was no significant difference between the two groups in terms of age, gestational age, occupation and education. The difference in the mean scores of nausea, vomiting and retching was not statistically significant between the control and intervention groups before the study. But four weeks after the study, a significant difference was observed in the mean scores of vomiting, nausea and retching between the two groups, so that the mean scores of vomiting, nausea and retching were significantly lower in the intervention group than in the control group. Conclusion: The ear acupressure medicine at the Shen men point can be used as a non-invasive, safe and inexpensive method to relieve nausea, vomiting and retching during pregnancy. Keywords: Acupressure medicine, Shen Men, Vomiting, Pregnancy, Nausea, Retching, Rhodosis

scholarly journals Kisspeptin: new biomarker of pregnancy

2019 ◽  
Vol 8 (8) ◽  
pp. 3021
Author(s):  
Priyanka Meena ◽  
Rati Mathur ◽  
Mohan L. Meena
Keyword(s):  
Pregnant Women ◽  
Gestational Age ◽  
Positive Relationship ◽  
Elisa Method ◽  
Medical College ◽  
Obstetrics And Gynaecology ◽  
Study Participants ◽  
Relationship Of ◽  
The Relationship ◽  
Single Blood Sample

Background: The recently identified hormone kisspeptin has been suggested to play an important regulatory role in placentation. The aim and objective of the study is the measurement of serum kisspeptin level in asymptomatic pregnant women and to find out the association of serum kisspeptin with gestational age in women with early pregnancy.Methods: This was a longitudinal study to the evaluation of 178 asymptomatic pregnant women with a gestation of 6 to 16 weeks attending routine antenatal booking visit recruited as study participants from the Antenatal Clinical of Obstetrics and Gynaecology Department, S.M.S. Medical College and Attached Hospitals, Jaipur, Rajasthan, India.Results: After initial clinical examination of every participant, a single blood sample was taken for the measurement of serum kisspeptin. Serum kisspeptin measurement test was performed by ELISA method and results were expressed as ng/ml. Pregnancy outcome was recorded prospectively. Mean serum kisspeptin level of study participants was 2.80±1.87ng/ml and median were 2.41 (Range 0.244-14.06ng/ml). Our result showed the relationship of serum kisspeptin with gestational age (GA) (p<0.000).Conclusions: serum kisspeptin level increases in pregnancy and showed positive relationship with gestational age significantly (p<0.000).

Sign in / Sign up

Export Citation Format

Share Document