scholarly journals Comparison of lipid levels in the diabetic and non diabetic patients: a study in a tertiary care hospital

2017 ◽  
Vol 4 (6) ◽  
pp. 1573 ◽  
Author(s):  
Vydehi Veeramalla ◽  
Swetha Madas
Keyword(s):  
Total Cholesterol ◽  
Tertiary Care ◽  
Diabetic Patients ◽  
Low Density ◽  
Care Hospital ◽  
Lipid Levels ◽  
Normal Range ◽  
Cholesterol Levels ◽  
Patients With Diabetes ◽  
High Density Cholesterol

Background: The incidence of coronary artery diseases is 3 to 5 times higher in both male and female diabetic patients compared to general population. Individuals with diabetes may have several forms of dyslipidemia leading to additive cardiovascular risk of hyperglycemia. This study was therefore conducted to identify the levels of lipidemia in the diabetic patients in our area.Methods: This study was conducted on 100 diabetic and 100 healthy patients, with 50 patients were males and 50 were females in both groups. Blood was collected in sodium fluoride tubes for all the patients for the estimation of glucose (both fasting and post prandial) and in serum tubes for lipids such as Triglycerides, Total cholesterol, High density cholesterol, Low density cholesterol and Very low density cholesterol.Results: The total cholesterol among the males who were diabetic was in the normal range in 46% and high in 20% of the patients. Among the control, i.e. non diabetic patients, 76% of them had total cholesterol in the normal range and high cholesterol levels were observed in only 8% of them. The levels of triglycerides, total cholesterol and LDL were significantly higher in the patients with diabetes, compared to the non diabetic patients. HDL in these patients was significantly low.Conclusions: The incidence of raised lipid levels in the diabetic patients is very high and since the elevated levels of lipids especially in these patients can lead to CHD and its complications, it is important for the monitoring of these levels throughout the course of the disease.

scholarly journals Efficacy of Statins in Dyslipidemia: A Non interventional comparative study in a tertiary care hospital, Ajman, UAE

2014 ◽  
Vol 4 (5) ◽  
pp. 428-432 ◽  
Author(s):  
LJ John ◽  
EM Esheiba ◽  
MAM Fathi ◽  
AK Agarwal ◽  
J Sreedharan ◽  
...  
Keyword(s):  
Total Cholesterol ◽  
Tertiary Care ◽  
Care Hospital ◽  
Newly Diagnosed ◽  
Lipid Levels ◽  
Treatment Groups ◽  
Cholesterol Levels ◽  
Significant Difference ◽  
Efficacy Measure ◽  
Baseline Values

BackgroundThe reduction of serum total cholesterol and LDL-cholesterol levels varies with different statins. The objective of the present study was to compare the efficacy of Simvastatin, Atorvastatin and Rosuvastatin in the treatment of newly diagnosed dyslipidemia.Material and Methods:A prospective, non-interventional 12-week study was conducted after approval from the Ethics Committee. A total of 70 patients with newly diagnosed dyslipidemia receiving 20mg of Simvastatin, Atorvastatin or Rosuvastatin were included. The primary efficacy measure was reduction of lipid levels from the initial baseline values at the end of 12 weeks with the respective Statins. Data was analyzed using descriptive statistics, Paired -t test, and analysis of variance (ANOVA).Results:Of total 70 patients, 14 patients received Simvastatin; 40 patients received Atorvastatin and 16 patients received Rosuvastatin. Demographic and baseline clinical characteristics were similar between the three groups. Significant reduction in lipid levels (total cholesterol, and LDL) was seen within the three treatment groups (p<0.01). However, statistically significant difference in the reduction lipid levels was not observed between the three groups.Conclusion:We found no significant difference in the reduction of lipid levels between Simvastatin, Atorvastatin or Rosuvastatin patients with newly diagnosed dyslipidemia.DOI: http://dx.doi.org/10.3126/nje.v4i5.12023 Nepal Journal of Epidemiology 2014; 4(5):428-32

Chiropody May Prevent Amputations in Diabetic Patients on Peritoneal Dialysis

2003 ◽  
Vol 23 (3) ◽  
pp. 255-259 ◽  
Author(s):  
Jennifer Lipscombe ◽  
Sarbjit V. Jassal ◽  
Susan Bailey ◽  
Joanne M. Bargman ◽  
Stephen Vas ◽  
...  
Keyword(s):  
Peritoneal Dialysis ◽  
Vascular Disease ◽  
Peripheral Vascular Disease ◽  
Tertiary Care ◽  
Diabetic Patients ◽  
Care Hospital ◽  
Peripheral Vascular ◽  
Foot Care ◽  
Care Assessment ◽  
Patients With Diabetes

← Background A multidisciplinary approach has been shown to be of benefit in the prevention of lower limb ulceration and amputation in patients with diabetes, but there is less information on the role of such an approach in patients receiving dialysis treatment. ← Objective The purpose of the present study was to determine whether the institution of a chiropody program would result in fewer amputations in diabetic patients on peritoneal dialysis (PD). ← Design Retrospective chart review. ← Setting The PD program at a tertiary-care hospital. ← Patients Patients with diabetes that were enrolled in the PD program between January 1997 and December 1999, inclusive, that were offered the opportunity to see a chiropodist, and that agreed to be seen. A total of 132 patients were included. ← Intervention Education about foot care, assessment, and, in some instances, treatment by a chiropodist. ← Results Patients with an amputation were more likely to be male ( p < 0.01) and have peripheral vascular disease ( p < 0.001) compared to those without an amputation. They also had a lower average mean arterial pressure ( p < 0.05), lower weekly creatinine clearance ( p < 0.01), higher mean erythropoietin dose ( p < 0.05), and longer duration of end-stage renal disease ( p < 0.001). Factors that were predictive of shorter time to death or amputation were older age [hazard ratio (HR) = 1.03, p < 0.05], peripheral vascular disease (HR = 2.66, p < 0.01), and cerebrovascular disease (HR = 2.70, p < 0.01). Being seen by a chiropodist was protective (HR = 0.39, p < 0.01). ← Conclusion The current study suggests that a chiropody program may help to prevent amputation in patients with diabetes on PD.

scholarly journals Pattern of lipid levels of subjects seeking laboratory services in an established laboratory in the Dhaka city

2017 ◽  
Vol 16 (3) ◽  
pp. 375-379
Author(s):  
Syeda Fahmida Afrin ◽  
Abu Kholdun Al Mahmood ◽  
Kaniz Fatima Bari ◽  
Ferdousi Rahman ◽  
Zahid Hassan
Keyword(s):  
Total Cholesterol ◽  
Tertiary Care ◽  
Colorimetric Method ◽  
Reference Level ◽  
Care Hospital ◽  
Dhaka City ◽  
Lipid Levels ◽  
Female Ratio ◽  
Medical College ◽  
Laboratory Services

Background: Dyslipidemia is linked to the risk for coronary ischemic and cardiovascular disease. Considering the absence of national reference level for lipids in Bangladesh the present study was undertaken to look into the pattern of lipid levels among patients seeking laboratory services in a private medical college hospital.Materials and Methods: This cross sectional study was carried out in Ibn Sina Medical College Hospital in Dhaka city. Patients with antilipid and other medication which might affect the outcome were excluded. Consenting and eligible subjects seeking laboratory services were included in the study. Total 970 subjects finally entered in the study. Total cholesterol [TC], triglyceride and HDL-cholesterol [HDL-c] were measured by enzymatic colorimetric method. LDL-cholesterol [LDL-c] was derived using Friedewald equation. Data were expressed mean±SD, number (percent) as appropriate. Statistical analyses were carried out using SPSS version 17 tool. A p value <0.05 was taken as level of significance.Results: Male female ratio of the total subjects was 53.9:46.1. Of the total participants 27.1% were between 41-50 age group and 71% were between 31-60 years. Mean (SD) triglyceride, total cholesterol, HDL-c and LDL-c level for all participants was 182±134, 194±44, 38.4±11.5 and 119±37 respectively. Mean value of HDL-c for all subjects was 38.4mg/dl where as it’s cutoff value is 40 mg/dl and 50 mg/dl for male and female respectively suggesting relatively large number of subjects had HDL-c dyslipidemia of the study subjects. Percent subjects with isolated abnormal lipid component were 51%, 41%, 73.2% and 33.3% for triglyceride, total cholesterol, HDL-c and LDL-c respectively. Of the total subjects 22% had abnormal level of lipid for all four components.Conclusions: The data showed pattern of lipid levels of the subjects seeking laboratory services of a tertiary care hospital which might be taken a trend in the Bangladeshi population. Dyslipidemia appeared to be relatively high among the subjects studied of which HDL-c dyslipidemia was more prominent.Bangladesh Journal of Medical Science Vol.16(3) 2017 p.375-379

To Study the Frequency of Albuminuria in Diabetics Brought in with Stroke: A survey at Tertiary Care Hospital

2021 ◽  
Vol 15 (6) ◽  
pp. 1302-1304
Author(s):  
A. Malik ◽  
A. Akhtar ◽  
F. F Jang ◽  
M. Uthman
Keyword(s):  
Ischemic Stroke ◽  
Economic Status ◽  
Strong Predictor ◽  
Microvascular Complications ◽  
Strong Association ◽  
Tertiary Care ◽  
Diabetic Patients ◽  
Care Hospital ◽  
College Hospital ◽  
Patients With Diabetes

Background: Albuminuria is thought to be a separate risk factor for stroke. A strong association between diabetes related albuminuria and stroke has been published in the international literature. Albuminuria being a sign of endothelial dysfunction, atherosclerosis is a strong predictor of strokes. Aim: To investigate the albuminuria as a predictor of stroke in diabetics in our population. Study design: Observational study. Place and duration of study: This study was done in the Department of Neurology, Sharif Medical & Dental College/Hospital, Lahore from January to August 2019. Methodology: One hundred and fifty diabetic patients having ages 25 to 75 years presented with stroke were enrolled in this study. Demographics (age, sex, residence and socio-economic status) of the included population and types of stroke were recorded on study proforma after getting brain CT of each patient. Urine for albuminuria was examined under microscope. Results: In this study (63%) were males and 37% were females with M:F ratio 2.54:1. Major portion of the patients (43%) were ages between 25-45 years mean±SD 51.62±8.45. Ischemic stroke was found in 114 (76%) hemorrhagic in 24(16%) and undetermined in 12(8%) patients respectively. Albuminuria was found in 72(48%) patients, Group A 40(69%) had ischemic stroke, 10(17%) had hemorrhagic and 8(14%) had undetermined stroke. Conclusion: It is concluded that is strong relation between microvascular complications with macrovascular complication of diabetes (i.e. albuminuria with stroke). The stoke patients with diabetes has more frequency of albuminuria as compared to non diabetics. Keywords: Albuminuria, T2DM, Stroke, Hemorrhagic.

scholarly journals Awareness of Foot Care Among Patients with Diabetes Mellitus attending a Tertiary Care Hospital

2018 ◽  
Vol 6 (02) ◽  
Author(s):  
Dr.P. Ganesh Kumar MS. ◽  
Dr.P. Venkateswaran MS ◽  
Damini. T
Keyword(s):  
Economic Status ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Diabetic Patients ◽  
Care Hospital ◽  
Foot Care ◽  
Cross Sectional ◽  
Patients With Diabetes ◽  
Good Score ◽  
Convenience Sampling

Objective: To assess the awareness of diabetes foot and care for foot in known diabetic patients. Methods: A cross- sectional study was carried out using non probability convenience sampling wherein 150 diabetic respondents who fulfilled the inclusion criteria were included. A pre tested questionnaire was used to assess their knowledge and practices regarding foot care. 14 questions were asked and one point was allotted for each of 7 questions among them. A score of more than 70% (5-7) was considered good, score of 40% - 70% (3 – 5) was considered satisfactory and less than 40% (below 3) was considered poor. Results: The age of the respondents selected was above 50 years. About 48.7% of the respondents had good awareness, 38.6% had satisfactory awareness and 12.7% had poor awareness. Literacy status of the respondents seems to have a significant association with their awareness. Economic status is not a significant factor.

scholarly journals Prevalence and pattern of dyslipidemia in newly detected type 2 diabetes mellitus and its correlation with anthropometric parameters

2021 ◽  
Vol 9 (8) ◽  
pp. 2362
Author(s):  
Cynthia A. Sukumar ◽  
Arunachalam Ramachandran ◽  
Sudeep K.
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Total Cholesterol ◽  
Tertiary Care ◽  
The Body ◽  
Diabetic Patients ◽  
Care Hospital ◽  
Anthropometric Parameters ◽  
Who Criteria

Background: Globally 425 million people have diabetes mellitus (DM) of which 90% are type 2 DM. India carries nearly 70 million cases of DM. India is called the diabetes capital of the world. The escalating epidemic of type 2 diabetes has been attributed to increasing obesity and longevity. Due to the additive cardiovascular risk of hyperglycemia and hyperlipidemia, lipid abnormalities should be aggressively detected and treated as a part of comprehensive diabetic care. The study aimed at detecting the occurrence and pattern of dyslipidemia in newly-detected type 2 diabetic patients in a tertiary care hospital in South India.Methods: This cross-sectional study was conducted over a period of eighteen months. It comprised of 50 newly detected diabetics above the age of 18 years who satisfied the inclusion and exclusion criteria.Results: Fifty patients were included in the study which included 18 males and 32 females. The body mass index (BMI) was abnormal in 62% (as per the Asian criteria) and in 42% (as per the WHO criteria). The waist circumference (WC) was found to be high in 82% and 70% as per the Asian and the WHO criteria, respectively. Forty six percent of the population was found to have elevated total cholesterol levels. LDL was increased in 70% of the study population while triglycerides were elevated in 40%, total cholesterol in 46% and low HDL in 76% of the patients.Conclusions: A significant correlation was found between the fasting blood sugars (FBSs) and serum triglycerides. There was a positive correlation noted between the dyslipidemia and the anthropometric parameters recorded.

scholarly journals Vision-threatening diabetic retinopathy necessitating vitrectomy in a tertiary care hospital in coastal Karnataka, South India

2020 ◽  
Vol 17 (1) ◽  
pp. 101-107
Author(s):  
Narasimha Vasista Reddy ◽  
Yogish Subraya Kamath ◽  
Lavanya G. Rao ◽  
Krishna Addoor Rao ◽  
Shailaja Bhat Shenoy ◽  
...  
Keyword(s):  
Diabetic Retinopathy ◽  
South India ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Diabetic Patients ◽  
Care Hospital ◽  
Cross Sectional ◽  
Screening Programs ◽  
Patients With Diabetes ◽  
Advanced Stages

Background: The proportion of diabetic patients having vision-threatening diabetic retinopathy and those needing to undergo vitrectomy was documented. Methods: A cross-sectional observational study was conducted at a tertiary care hospital in coastal Karnataka, South India. All patients with diabetes mellitus visiting the ophthalmology department in the study period were screened for retinopathy, and the data regarding the presence of maculopathy and proliferative retinopathy were included as vision-threatening retinopathy. Results: Of the 1,435 diabetic patients included, 38.4% had retinopathy changes due to diabetes, with 8.71% having vision-threatening retinopathy and 1.81% needing vitrectomy. Conclusion: Although the proportion of vision-threatening retinopathy is small, the rapidly increasing diabetic population requires the setting up of more resources for tackling this condition, at least at the tertiary levels of the health-care system. However, considering the increased human and economic resources involved in setting up vitrectomy units, more emphasis on strengthening screening programs for early detection and referral to reduce the progression of retinopathy to advanced stages would be appropriate.

Prescribing trends of antidiabetic drugs in diabetic and hypertensive diabetic patients in an urban tertiary care hospital of Bangladesh

2017 ◽  
Vol 3 (3) ◽  
pp. 338-343
Author(s):  
Mohammad Didar Khan ◽  
Md. Ibrahim ◽  
Md. Mizanur Rahman Moghal ◽  
Dipti debnath ◽  
Asma Kabir ◽  
...  
Keyword(s):  
Urban Areas ◽  
Tertiary Care ◽  
Diabetic Patients ◽  
Care Hospital ◽  
Age Group ◽  
Microsoft Excel ◽  
Patient Profile ◽  
Prescribing Trends ◽  
Medical University ◽  
Insight Into

Objective: The present epidemiological study was conducted with the objectives of providing an insight into the current use of antidiabetic medications to diabetics and hypertensive diabetics in urban areas and determining how the patient factors influence the prescribing of antidiabetic medications. Methodology: Data of patients of past two years were collected from Bangabandhu Sheikh Mujib Medical University (BSMMU) Hospital, Dhaka, Bangladesh. The details were entered in the structured patient profile form. Data were statistically analyzed using the Microsoft Excel 2007 software. Result: A total of 958 patient’s data were collected and analyzed of which 632 (65.97 %) were males and 326 (34.03 %) were females. These patients were further categorized based on their age. 330 patients (34.45 %) belonged to the age group 20 – 44 years, 504 (52.61 %) to the age group 45 – 65 years and 124 (12.94 %) to the age group 65 – 80 years. 684 (71.4%) patients out of the 958 patients studied were suffering from coexisting hypertension. Co-existing hypertension was found to be more prevalent in the age group 45 – 65 years (67.69%) and was found more in females (84.04%). Conclusion: Metformin was the oral hypoglycemic which was the highest prescribed. In hypertensive diabetics Metformin and Pioglitazone were most frequently prescribed drugs. Biguanides and Insulin were the most commonly prescribed antidiabetics. A combination of two or more drugs of different classes was prescribed to hypertensive diabetics. It is necessary to have an improved understanding of the etiology and pathophysiology of diabetes to focus on research efforts appropriately.

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