Dietary practices in type 2 diabetes patients at Bhopal, Madhya Pradesh: a cross-sectional study

Background: Diabetes mellitus (DM) is a rapidly growing health problem in India. Diet and physical activity are important modifiable risk factors affecting the incidence, severity and management of DM. The aim of the study was to assess diet of diabetes mellitus patients. 87 adults from a cohort of diabetic patients attending the Medical Clinics at the Hamidia Hospital Bhopal were invited for the study.Methods: Information about their nutritional status & food consumption pattern was taken by 24-hour dietary recall and food frequency questionnaire. Data was analysed using Epi Info and MS Excel. Frequency counts and percentages were used to describe the demographic characteristics of the participants while the significance difference in between male and female participants. The significance level was set at P <0.05 and 0.01. Statistical analysis used: MS Excel and Epi Info.Results: The study sample was 87 out of which 56 were females and 31 were males; mean age of DM patients was 48.21±12.98.The mean energy intake was 1386.52 kcal and 1125.79 kcal among male and female. The mean protein intake was 68.71 g and 50.50 among male and female diabetics. There was significant difference between male and female age. There were no significant difference in body mass index and waist hip ratio between male and female. 30 (34.5%) & 16 (18.4%) were overweight and obese respectively.Conclusions: Based on these findings, the dietary practices of diabetic patients are inadequate and require improvement. Education and counselling about diet of a diabetes patient is needed.

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Genetic homozygosity as a marker of smoking dependency

Genetika ◽

10.2298/gensr203009b ◽

2020 ◽

Vol 52 (3) ◽

pp. 1009-1019

Author(s):

Slavko Brankovic ◽

Dejan Nikolic ◽

Dragoslav Marinkovic ◽

Suzana Cvjeticanin

Keyword(s):

Cross Sectional Study ◽

Male Gender ◽

Sectional Study ◽

Cross Sectional ◽

Male And Female ◽

Mean Values ◽

Individual Variations ◽

Significant Difference ◽

The Mean ◽

The Individual

The aim of our study was to evaluate the morphogenetic variability as a marker of smoking dependency in adult smokers versus controls and to investigate the presence and the degree of morphogenetic variability difference between male and female smokers versus same gender controls. The cross-sectional study evaluated 241 smokers and 185 nonsmoker individuals as controls. We analyzed 17 homozygous recessive characteristics (HRC). There was a significant difference in the individual variations of 17 HRCs between the controls and smokers (??2=61.400, p<0.001; for females ??2=79.440, p<0.001; for males ??2=84.972, p<0.001). The mean values of HRCs significantly differed between smokers and controls (MV?SEM(Controls) -4.79?0.13, MV?SEM(Smokers) -5.70?0.12; p<0.001). For males, presence of 6/17 (35.29% genetic homozygosity) HRCs (OR=6.12) was to the certain degree predictor for smoking dependency. Higher degree of genetic homozygosity, changed variability and male gender, might be some among potential numerous factors that could have impact on smoking development and dependence.

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Myeloperoxidase as an Important Predictor of Cardiovascular Risk in Individuals with Rheumatoid Arthritis

10.21203/rs.3.rs-641421/v1 ◽

2021 ◽

Author(s):

Elisangela Gueiber Montes ◽

Fabiana Postiglioni Mansani ◽

Alceu de Oliveira Toledo Júnior ◽

Marcelo Derbli Schafranski ◽

Bruno Queiroz Zardo ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Cardiovascular Risk ◽

Cross Sectional Study ◽

Important Predictor ◽

Diabetic Patients ◽

Glucocorticoid Treatment ◽

Cross Sectional ◽

Significance Level ◽

Dose Time ◽

Significant Difference

Abstract Background: Rheumatoid arthritis is an inflammatory disease with joint manifestations. In the presence of extra-articular manifestations, the morbidity and severity of the disease increases. Glucocorticoid is used as a treatment and may result in side effects related to cardiovascular risk. Methods: This was a cross-sectional study including 59 volunteers with rheumatoid arthritis receiving treatment at a Hospital of Campos Gerais, that aimed to establish the relation between cardiovascular risk, glucocorticoid treatment and myeloperoxidase in these patients. Subjects were divided into two groups: using (n = 39) and without glucocorticoids (n = 20). They underwent clinical evaluation, physical examination and blood samples were taken. Statistical analysis was performed using Student's t-test and Mann-Whitney test. Logistic regression was performed to assess cardiovascular risk. The significance level was 5% (α = 0.05). Calculations were performed using the Statistical Package for the Social Science version 21.0. Results: There has been a significant difference between groups in blood glucose values (p = 0.012), that can be explained by the different percentage of diabetic patients in the groups. When assessed cardiovascular risk using the predictors of glucocorticoid dose, time of glucocorticoid use, myeloperoxidase, and C-reactive protein together, these were responsible for significantly predicting cardiovascular risk (p = 0.015). Conclusions: A significant relation between the predictor myeloperoxidase alone was also demonstrated (p = 0.037), may it be an important predictor of cardiovascular risk among individuals with rheumatoid arthritis.

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Exposure Assessment of Artificial Sweeteners among Type 2 Diabetic, Overweight and Obese Individuals

The Indian Journal of Nutrition and Dietetics ◽

10.21048/ijnd.2016.53.3.5297 ◽

2016 ◽

Vol 53 (3) ◽

pp. 268

Author(s):

A. Bhagyasri ◽

R. Naveen Kumar ◽

N. Balakrishna ◽

V. Sudershan Rao

Keyword(s):

Exposure Assessment ◽

Daily Intake ◽

Cross Sectional Study ◽

Consumption Pattern ◽

Cross Sectional ◽

Significant Difference ◽

Overweight Group ◽

The Mean ◽

Type 2 Diabetic

In recent years consumption of artificially sweetened foods and beverages became popular in India, with the regulatory formulations to use them in selected foods; their inclusion especially in sweets, biscuits and beverages has increased. There are many concerns rising regarding their safety and is becoming an area of controversy. So an exposure assessment has been carried out to evaluate intake levels among type II diabetic, overweight and obese individuals. A cross-sectional study design was applied and a food frequency questionnaire was used to obtain the information on consumption pattern. Range, standard deviation and mean daily intake levels were calculated and the values were compared with an appropriate Acceptable Daily Intake (ADI). Results indicated that, the mean daily intake levels of aspartame (0.85±0.75) were found to be high among type 2 diabetic individuals whereas sucralose (0.41±0.41) and acesulfame-k (0.07±0.02) were high among overweight group. There was a significant difference (p<0.0001) observed in intake levels among both groups and all the sweeteners were found to be well within the ADI levels.

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Oxidative stress in chronic periodontitis patients with type II diabetes mellitus

European Journal of Dentistry ◽

10.4103/ejd.ejd_244_17 ◽

2018 ◽

Vol 12 (02) ◽

pp. 225-231 ◽

Cited By ~ 4

Author(s):

Ruby Ramya Vincent ◽

Devapriya Appukuttan ◽

Dhayanand John Victor ◽

Aruna Balasundaram

Keyword(s):

Oxidative Stress ◽

Diabetes Mellitus ◽

Periodontal Disease ◽

Diabetic Patients ◽

Clinical Parameters ◽

Type Ii ◽

Chronic Periodontal Disease ◽

Significant Difference ◽

The Mean ◽

Group 1

ABSTRACT Objective: Oxidative stress (OS) refers to the disequilibrium between free radicals and antioxidant defense mechanisms and is significantly implicated in the pathogenesis of chronic degenerative and inflammatory diseases such as chronic periodontal disease (CP) and diabetes mellitus (DM). This study aimed to evaluate the total antioxidants capacity (TAOC) and total oxidants status (TOS) in the gingival crevicular fluid (GCF) in CP participants with type II DM. Materials and Methods: A total of 80 participants were allotted into four groups as follows: Group 1: Generalized CP (GCP) without type II DM (n = 20); Group 2: GCP with type II DM (n = 20); Group 3: Type II DM without CP (n = 20); and Group 4: Systemically and periodontally healthy (PH) (n = 20). Clinical parameters such as plaque index, gingival index, probing pocket depth, and clinical attachment level were recorded. Pooled GCF was collected followed by the estimation of TAOC, TOS, and OS index (OSI) using Erel O Colorimetric analysis. Results: The clinical parameters recorded showed the statistically significant difference (P < 0.001) between the groups. The mean TAOC value was the highest in PH group. The mean TOS and OSI were higher in Group 1, 2, and 3 participants when compared to the PH participants. All the biochemical parameters evaluated showed a statistically significant difference (P < 0.001) between groups. Conclusions: The study further validates the use of OSI as a marker for periodontal disease activity and emphasizes the role of OS in the pathogenesis of Type II diabetic patients with the chronic periodontal disease.

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Quality of Life in Type 2 Diabetic Patients

Acta Facultatis Medicae Naissensis ◽

10.2478/afmnai-2014-0024 ◽

2014 ◽

Vol 31 (3) ◽

pp. 193-200 ◽

Cited By ~ 7

Author(s):

Ana Spasić ◽

Radmila Veličković Radovanović ◽

Aleksandra Catić Đorđević ◽

Nikola Stefanović ◽

Tatjana Cvetković

Keyword(s):

Quality Of Life ◽

Diabetes Mellitus ◽

Short Form ◽

Diabetic Patients ◽

Type 2 Diabetic Patients ◽

Cross Sectional ◽

Significant Difference ◽

Type 2 Diabetic

Summary The presence of diabetes mellitus leads to a decrease in life quality in all domains. The aim of our study was to evaluate the quality of life (QOL) in diabetic patients and the factors affecting it in type 2 diabetic mellitus patients. We conducted a cross-sectional study that included 86 patients with type 2 diabetes mellitus, in the territory of the City of Niš. Health-related QOL of patients was measured using the short form survey (SF-36) that produces an 8-scale health profile. The average duration of diabetes was 12.76±8.08 years. The best QOL in all areas was observed in patients diagnosed with diabetes less than 10 years ago p<0.05) and younger than 65 years. Male respondents perceived a better QOL compared to women, especially in the vitality and pain domains. The patients with comorbidity (93.64%) had lower QOL score in all domains. There was no significant difference in the QOL of patients with diabetes compared to the level of education. High QOL represents an ultimate goal and an important outcome of all medical interventions in diabetic patients. Factors related to lower QOL included: older age, female gender, and existence of comorbidities. Uncontrolled diabetic patients had a lower QOL than controlled diabetics.

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Psychological Study of Anxiety among Diabetic Patients

International Journal of Indian Psychology ◽

10.25215/0501.028 ◽

2017 ◽

Vol 5 (1) ◽

Author(s):

Parth R. Desai

Keyword(s):

Diabetic Patient ◽

Urban Area ◽

Rural Area ◽

T Test ◽

Anxiety Scale ◽

Diabetic Patients ◽

Male And Female ◽

Psychological Study ◽

Significant Difference ◽

The Mean

The main aim of the present study is to find out the level of Anxiety among diabetic patient. It was hypothesized that the level of and Anxiety will differ in diabetic patients with regards to gender and type of area. The sample consists of total 120 (60 patients of urban and 60 patients of rural area) the sample is selected from city and various villages, by using purposive technique. Anxiety scale prepared by A.K.P. Sinha and L.N.K. Sinha devised this test and it is available both test in Hindi and English. Gujarati Adoption by Bhatt D. J. (1999). The data was scored, analyzed as per the manual. ‘t’ test was being calculated. The result showed that (1) There is no significant difference between the mean score of anxiety among male and female diabetic patient. (2) There is significant difference between the mean score of anxiety among type of area i.e. urban and rural. Thereafter could be said that, diabetic patient of rural area show more anxiety than diabetic patient of urban area.

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Evaluation of sweet taste sensitivity in type-II Diabetes Mellitus patients

International Journal of Clinical and Biomedical Research ◽

10.31878/ijcbr.2020.63.03 ◽

2020 ◽

pp. 10-12

Author(s):

Z. Naveen Kumar ◽

B.N.S. Gowri Kumari

Keyword(s):

Diabetes Mellitus ◽

Type Ii Diabetes ◽

Type Ii Diabetes Mellitus ◽

Sweet Taste ◽

Cross Sectional Study ◽

Taste Sensitivity ◽

Diabetic Patients ◽

Type Ii ◽

Cross Sectional ◽

The Mean

Background: The objective is to evaluate the sweet taste sensitivity among type-II diabetes mellitus patients. Methods: This is a cross sectional study consisted of 227 subjects (127 type-II Diabetic patients & 100 non diabetic individuals) of both the genders and age matched. Sweet taste sensitivity tests were done using different concentrations of glucose solution and compared among the diabetic patients with FBS more than 180mg/dl and diabetic patients with FBS less than 180mg/dl and also compared among the diabetic patients and non diabetic individuals. The final concentration at which patient was able to perceive the taste was recorded. statistical analysis was done using Student’s unpaired T test. Pvalues of < 0.05 were considered to be statistically significant. Results: The mean of sweet taste sensitivity among diabetic patients with FBS >180 mg/dl was 6245 mg/l and the mean of sweet taste sensitivity in the diabetic patients with FBS <180 mg/dl was 2249mg/l with P<0.001 which is significant. The mean of sweet taste sensitivity among diabetic patients with FBS >180 mg/dl was 6245mg/l and the mean of sweet taste sensitivity in the non diabetic individuals was 1979mg/l with P<0.01 which is significant. the mean of sweet taste sensitivity among diabetic patients with FBS <180 mg/dl was 2249 mg/l and the mean of sweet taste sensitivity in the non diabetic individuals was 1979mg/l with P>0.05 which is not significant. Conclusion: In our study it was concluded that type-II Diabetes Mellitus patients have lesser sensitivity for the sweet taste. Loss of sensitivity leads to the increase in sugar consumption being the risk factor for worsening the disease.

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Gender based variation of lipid abnormalities in type-2 diabetes mellitus patients

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20213934 ◽

2021 ◽

Vol 9 (10) ◽

pp. 3068

Author(s):

Arpita Jaidev ◽

Hitesh Shah ◽

Liggy Andrews ◽

Bhavisha N. Vagheda

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Total Cholesterol ◽

Blood Sugar ◽

Density Lipoprotein ◽

Diabetic Patients ◽

Male And Female ◽

Significant Difference

Background: Dyslipidemia has a varying pattern among the male and female patients of type 2 diabetes mellitus (DM).Methods: This study was conducted in the out-patient department (OPD) of department of medicine at GMERS, Patan, Gujarat from July 2020 to December 2020 for a period of six months. Fasting blood sugar, hemoglobin A1c (FBS, HbA1c) lipid profile triacylglycerol-triglyceride, total cholesterol, low density lipoprotein cholesterol and high-density lipoprotein cholesterol (TG, TC, LDL-C, and HDLC) were measured. Statistical analyses were performed with the SPSS software program.Results: A total number of 200 type 2 DM patients (100 males and 100 females) attending to GMERS OPD were recruited in this study. Blood sugar was higher than normal in both male and female (FBS=142.44±36.21, 146.40±41.49 respectively). TG level was also higher in two groups of study subjects with female level slightly more than male (164.99±67.1and 138.21±70 respectively) with no significant difference between the groups (p>0.05).Total cholesterol and LDL-C level was within normal physiological level in both groups, where-as these levels were higher in female in comparison to male (TC=198.07±40.82 and 169.5±36.13 respectively, LDLC=118±34 and 99±27, respectively), showing significant difference between the groups (p=0.014). HDL-C was not below normal in both male (41±5.4) and female (43.99±4.31); however, HDL-C was slightly higher in female than male and the difference was significant (p=0.0129).Conclusions: Dyslipidemia was noticed in a greater proportion of female diabetic patients than male diabetic patients.

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EFFECT OF DIABETES MELLITUS ON RIFAMPICIN PEAK SERUM CONCENTRATION

International Journal of Pharmacy and Pharmaceutical Sciences ◽

10.22159/ijpps.2016v8i10.13238 ◽

2016 ◽

Vol 8 (10) ◽

pp. 149

Author(s):

Saranya P. ◽

Parthasarathy V. ◽

Hariprasad B. ◽

Shobha Rani H.

Keyword(s):

Diabetes Mellitus ◽

Serum Concentration ◽

Pulmonary Tuberculosis ◽

Tertiary Care ◽

Peak Serum Concentration ◽

Peak Serum ◽

Diabetic Patients ◽

Care Hospital ◽

Significant Difference ◽

The Mean

Objective: To comparatively analyze the peak serum concentration (Cmax) of rifampicin and to determine the incidence of decreased Cmax between diabetic and non-diabetic adult pulmonary tuberculosis patients.Methods: A cross-sectional observational study was carried out in the chest and tuberculosis (TB) department of a tertiary care hospital after the approval of the institutional ethics committee. Five millilitre (ml) of blood was withdrawn by venipuncture from each patient at a time point of 2 h post dose administration at steady state concentration (Css). The separated serum was centrifuged at a rate of 3500 rotations per minute (rpm) for a period of fifteen minutes and the resultant serum was stored at-70 ° C until analysis. Estimation of rifampicin concentration was carried out in Thermo TSQ Ultra (MS/MS) with Shimadzu 20 AD UFLC LC-MS.Results: The mean (Standard Deviation (SD)) age of the study population was 46.8 (14.2) years. The mean serum Cmax of rifampicin was significantly less in diabetic patients with pulmonary tuberculosis (p=0.0305). Statistically, a significant difference in the incidence of a decrease in Cmax was found between diabetic and non-diabetic patients (p=0.0335). Diabetes mellitus was found to be the predominant factor that affects rifampicin Cmax.Conclusion: In this study, an effect of diabetes mellitus (DM) on the peak serum concentration of rifampicin was observed. Patients with hyperglycemia levels had significantly reduced levels of rifampicin serum concentrations, thus showing an inversely proportional relationship between blood glucose and rifampicin serum levels.

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Kromium serum dan asupan mikromineral pada penyandang diabetes tipe 2

Jurnal Gizi Klinik Indonesia ◽

10.22146/ijcn.18883 ◽

2017 ◽

Vol 13 (4) ◽

pp. 135

Author(s):

Ni Ketut Sutiari ◽

Rimbawan Rimbawan ◽

Clara Meliyanti Kusharto ◽

Purwantyastuti Ascobat ◽

Adi Teruna Effendi

Keyword(s):

Health Care ◽

Primary Health Care ◽

Diabetic Patients ◽

Cross Sectional ◽

Zinc Intake ◽

Primary Health ◽

Serum Chromium ◽

Significant Difference ◽

Aas Method ◽

The Mean

Background: Status of minerals such as zinc, magnesium, and chromium among diabetic patients are considered lower than non-diabetic peoples, both in the serum and intake. Some reviews show that those minerals contribute to carbohydrate metabolism among diabetic patients.Objective: This study aims to explore intake of zinc, magnesium, and chromium among DMT2 in Denpasar.Method: This is a cross-sectional analytic study. The population was all (70) DMT2 patients registered at Chronic Disease Service (Prolanis) at two Primary Health Care (PHC) Denpasar Utara III PHC and Denpasar Timur I PHC. The sample for the study was DMT2 patients and non-diabetic people age 50-70 years reside in Denpasar city. DMT2 patients were randomly selected with simple random technique, while non-diabetic peoples were non-randomly selected. The level of serum chromium was measured by AAS method, whereas microminerals intake were collected by a recall and SQ-FFQ method. Data was analyzed descriptively and differences were tested with two independent t-test at 95% confidence level.Results: The mean of serum chromium DMT2 and non-diabetic were 0.044 mg/L and 0.094 mg/L respectively. The mean±SEM magnesium (DMT2 316.1±22.4 mg/day; non-diabetic 211.0±33.5 mg/day), zinc intake was (DMT2 8.4±0.7 mg/day; non-diabetic 6.2±0.8 mg/day), and chromium (DMT2 10.8±1.3 µg/day; non-diabetic 8.7±0.9µg/day). A significant difference was found between magnesium intake (p=0.01).Conclusion: The study showed that zinc, magnesium and chromium intake is appeared higher among DMT2 patients compare to non-diabetic in Denpasar region.

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