scholarly journals A retrospective analysis of clinical profile of patients with cancer cervix in a rural medical college in Karnataka

2021 ◽  
Vol 8 (4) ◽  
pp. 502-506
Author(s):  
Bhavya H U ◽  
Muna Ellian ◽  
Geeta J Doppa
Keyword(s):  
Cervical Cancer ◽  
Socioeconomic Status ◽  
Low Socioeconomic Status ◽  
Invasive Cervical Cancer ◽  
Clinical Profile ◽  
Reproductive Age ◽  
Clinical Staging ◽  
Cancer Cervix ◽  
Medical College ◽  
Clinical Records

Cancer cervix is most common cause of cancerous deaths in females especially in developing countries. The pre-invasive stage of cervical cancer lasts for a long period and a small proportion progresses to an invasive lesion. In Indian set up, majority of the patients are presenting with an invasive lesion. To describe the clinical profile of patients presented with cervical cancer and to describe various treatments received by those patients.: The present study is a retrospective observational study done on confirmed cases of carcinoma cervix who attended rural medical college in Karnataka. Clinical records of the patients, who presented between November 2019 and November 2020 and were diagnosed with cervical cancer, were retrieved. The data related to demographic and clinical variables like age, socioeconomic status, education, symptoms, clinical staging, treatment and histopathology report were recorded. Data collected were entered in Microsoft Excel Office 2007and data analysed. Data were presented using descriptive statistics. The data was expressed in the form of frequencies and percentagesA total of 30 patients with the median age of 46 years were studied. Most common presentation was post coital bleeding (40%) followed by white discharge per vagina in 33%. Majority were under low socioeconomic status (70%). 60% presented in stage II and 30% in stage I. Chemoradiation was treatment of choice in 60% followed by surgery in 33% and 7% were lost to follow up. On histopathology, majority had squamous cell carcinoma (70%).The appropriate management of Cervical intraepithelial neoplasia(CIN) can prevent invasive cervical cancer. In this study most of them presented in advanced stage which could have been prevented with the regular screening and awareness among women in the reproductive age group. : Detection of pre invasive lesions or in situ cases remains important key to decreasing cervical cancer morbidity and mortality.

scholarly journals Increase Suicidal Mortality Rate Among Females in District Peshawar

2018 ◽  
Vol 5 (1) ◽  
pp. 18-21
Author(s):  
Farooq Ahmed Abro ◽  
Rizwan Zafar Ansari ◽  
Muhammad Yousaf ◽  
Riaz Gul ◽  
Anwar UI Haq ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Low Socioeconomic Status ◽  
Reproductive Age ◽  
Cultural Norms ◽  
Medicine Department ◽  
Low Socioeconomic ◽  
Medical College ◽  
Unwanted Pregnancies ◽  
Health Related ◽  
Almost All

OBJECTIVE: To study increased suicidal mortality rate among females in district Peshawar. METHODOLOGY: The bodies of women in the reproductive age who died because of fatal deliberate self-harming were examined at Forensic Medicine Department Khyber Medical College, Peshawar from January 2015 to September 2015. RESULTS: Forty-four bodies of females were autopsied. 13 (30%) were adolescents between the age of 10-18 years. 31 (70.4%) were aged between 19-48 years. 33 of the victims committed suicide due to health-related issues. 28 (64%) victims used poisons. In almost all cases (n=38) the incident happened when the victim was alone in house or left unattended. 30 (68%) victims were brought to hospitals for treatment. 13 were found to have recurrent attempt of self-harming. CONCLUSION: Females have increased tendency to commit suicide than males especially in their reproductive age. Low socioeconomic status, cultural norms, unwanted pregnancies and ill health are the major causes.

scholarly journals Experience of performing radical trachelectomy with uterine transposition in organ-preserving treatment of stage IB-II invasive cervical cancer

2021 ◽  
Vol 67 (1) ◽  
pp. 85-90
Author(s):  
Alyena Chernyshova ◽  
Vitaly Аntipov ◽  
Larisa Коlomiets ◽  
Vladimir Chernov ◽  
Victor Gyunter ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Radiation Therapy ◽  
Assisted Reproductive Technologies ◽  
Invasive Cervical Cancer ◽  
Reproductive Technologies ◽  
Reproductive Age ◽  
Treatment Modalities ◽  
Combined Modality Treatment ◽  
Radical Trachelectomy ◽  
Stage Ib

The development and implementation of organ-preserving treatment modalities is the priority trend in the current cancer treatment of patients of the reproductive age. Methods of expanding indications for organ-preserving treatment in cancer patients are becoming relevant. We present our experience in performing radical trachelectomy with uterine transposition in patients with stage IB-II cervical cancer. Our surgical technique allows the preservation of the uterus and adnexa in patients with invasive cervical cancer, who need to receive combined modality treatment including extended surgery followed by chemotherapy or radiation therapy to the pelvis. Transposition of the uterus and adnexa after radical abdominal or laparoscopic trachelectomy allows the movement of the uterus and ovaries out of the radiation field. After completion of radiation therapy, the uterus with adnexa is repositioned into the pelvis and uterine-vaginal anastomosis is formed using an implant made of titanium nickelide. Independent pregnancy and the use of assisted reproductive technologies are permitted after passing the time when distant metastases are most likely to develop.  

Utilization of Diagnostic Studies in the Pretreatment Evaluation of Invasive Cervical Cancer in the United States: Results of Intergroup Protocol ACRIN 6651/GOG 183

2005 ◽  
Vol 23 (30) ◽  
pp. 7454-7459 ◽  
Author(s):  
Marco A. Amendola ◽  
Hedvig Hricak ◽  
Donald G. Mitchell ◽  
Bradley Snyder ◽  
Dennis S. Chi ◽  
...  
Keyword(s):  
United States ◽  
Cervical Cancer ◽  
Data Analysis ◽  
Diagnostic Tests ◽  
Gynecologic Oncology ◽  
Invasive Cervical Cancer ◽  
The United States ◽  
Patterns Of Care ◽  
Clinical Staging ◽  
Gynecologic Oncology Group

Purpose To review the current utilization of diagnostic tests prescribed by the International Federation of Gynecology and Obstetrics (FIGO) clinical staging guidelines in the pretreatment work-up of invasive cervical cancer, and to compare the data with those of previous patterns of care studies. Patients and Methods This interdisciplinary American College of Radiology Imaging Network/Gynecologic Oncology Group prospective clinical trial was conducted between March 1, 2000, and November 11, 2002. Twenty-five participating institutions, all from the United States, enrolled a total of 208 patients. Only patients scheduled for surgery with biopsy-confirmed cervical cancer of clinical FIGO stage IB or higher were eligible. The patterns of care data analysis was based on 197 patients who met all inclusion criteria. The conventional FIGO-recommended tests used for pre-enrollment FIGO clinical stage classification were at the discretion of the treating physician; overall frequency of use was tabulated for each test. Results Use of cystoscopy (8.1%) and sigmoidoscopy or proctoscopy (8.6%) was significantly lower than in 1988 to 1989 (P < .0001 in each instance). Intravenous urography was used in only 1% of patients as compared with 42% in 1988 to 1989 and 91% in 1983. No patient included in the data analysis had barium enema or lymphangiography. Only 26.9% of patients had examination under anesthesia for FIGO clinical staging. Conclusion There is a large discrepancy between the diagnostic tests recommended by FIGO and the actual tests used for cervical cancer staging, suggesting a need to reassess the relevance of the FIGO guidelines to current clinical practice in the United States.

Neoadjuvant chemotherapy for locally advanced cervical cancer: Experience at the Instituto Oncologico Nacional SOLCA Guayaquil.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e15571-e15571
Author(s):  
Guillermo Paulson ◽  
Katherine Garcia ◽  
Mayra Santacruz ◽  
Ruth Ginger Engracia ◽  
Jose Francisco Mendoza
Keyword(s):  
Cervical Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Invasive Cervical Cancer ◽  
Locally Advanced ◽  
Progression Free Survival ◽  
Complete Response ◽  
Median Number ◽  
Number Of Cycles ◽  
Clinical Records ◽  
Cancer Experience

e15571 Background: Cervical cancer is the most common malignancy of women in Ecuador. The main problem of concomitant chemo-radiotherapy (CRT) is the delay in starting radiation therapy, economic and logistical problems for high demand in radiotherapy. It has been neoadjuvant chemotherapy (NACT) followed by CRT the main treatment at our center in order to find an alternative to long waits before the start of radiotherapy. The aim of this study was to determine the response to NACT followed by CRT in terms progression-free survival (PFS) and overall survival (OS). Methods: diagnosed with invasive cervical cancer locally advanced stage II-III were analyzed retrospectively reviewed clinical records of pre-existing data from 2008 to 2010. Results: after meeting the criteria of exclusion, leaving 116 cases. The median age: 49 years (range: 28-82 years). The histology was 73% (85) squamous cell carcinoma, 26% (30) adenocarcinoma and 0.9% (1) not specified. Patients with stage IIB: 81.9% (95), IIIA: 10.3% (12), IIIB: 7.8% (9). Of the 116 patients 69% (80) received NACT. The main NACT was paclitaxel 175mg/m2 + Cisplatin 75mg/m2 every 3 weeks 63.8% (74), the remaining group received another protocol, the median number of cycles of NACT was 5 (1 - 8 cycles), the start of radiotherapy since the conclusion of NACT was 53 days on average (1 to 285 days) and the main regimen of CRT concomitant was cisplatin 40mg/m2 weekly 47.5% (38). In the 49 patients who underwent NACT followed by CRT, a radiological study showed, complete response (CR) 38.8% (19), 18.4% partial response (PR) (9), disease progression (DP) 12.2% (6), stable disease (SD) 8.2% (4) and the end of treatment evaluation gynecological was performed and CR was obtained in 59.2% (29). Persistent or progressive disease after treatment was 22.4% (11), recurrence was 12.2% (6), local recurrence 2.0% (1), distant metastasis 10.2% (5). OS of NACT followed by CRT was 93.9% (46) and PFS was 65.3% (32), OS after CR was 96% (25 / 1) and then 91.7% PR (24 / 2) with p: 0.439. Conclusions: NACT followed by CRT is a valid option because it improves disease-related symptoms, but OS did not improve significantly even after CR.

Impact of socioeconomic status and degree of ethnic isolation on cervical cancer incidence among Hispanics and Asians in California.

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. 5605-5605
Author(s):  
Marie-Anne Froment ◽  
Audrey Roux ◽  
Mindy C. DeRouen ◽  
Scarlett Lin Gomez ◽  
Elizabeth A. Kidd
Keyword(s):  
Cervical Cancer ◽  
Socioeconomic Status ◽  
Cancer Incidence ◽  
Pap Smear ◽  
Invasive Cervical Cancer ◽  
The United States ◽  
Asian Women ◽  
Low Ses ◽  
Cervical Cancer Incidence ◽  
The Impact

5605 Background: The incidence of cervical cancer in the United States has declined since the introduction of the pap smear. However, differences exist based on ethnicity and socioeconomic status (SES).This study aimed to evaluate the impact of nativity, neighborhood SES and enclave (degree of ethnic isolation) on the incidence of cervical cancer in California. Methods: Using data from the California Cancer Registry, comprising three of the National Cancer Institute’s Surveillance Epidemiology and End Results (SEER) program registries, information on all primary invasive cervical cancer diagnosed in California from January 1, 1990, through December 31, 2004 was obtained. We analyzed the influence of enclave, SES, and nativity on cervical cancer incidence. Results: Among the 22,189 invasive cervical cancer cases diagnosed between 1990 and 2004, 50% were non-Hispanic white (NHW), 39% Hispanic and 11% Asian women. Seventy percent (70%) of the invasive cervical cancer cases were squamous cell carcinoma (SCC), 19% were adenocarcinoma and 11% other histologies. Approximately half (51%) of patients presented with localized disease, 33% regional disease, 10% distant disease and 6% unknown. By ethnic group, US born women showed lower rates of SCC compared to foreign-born women. Seventy-six percent (76%) of invasive cervical cases were observed in high enclave neighborhoods, and seventy percent (70%) were noted in low SES neighborhoods. Hispanics living in low SES and high enclave had 12.7 times (95% CI; 11.2-14.3) higher rate of cervical cancer than those living in high SES, low enclave neighborhoods. For Asian women incidence rates were 6 times (95% CI; 4.9-7.5) higher in the low SES, high enclave neighborhoods compared to those living in high SES, low enclave neighborhoods. Conclusions: More efforts should be done to reach out to and increase pap smear screening for women living in high enclave neighborhoods to help decrease the incidence of invasive cervical cancer cases in these groups of women.

scholarly journals Incidence of H. pylori in all Endoscopies Done at Saveetha Medical College over the Last Two Years (2018-2020)

2021 ◽  
pp. 293-298
Author(s):  
S. Kirthika ◽  
M. Vinoth
Keyword(s):  
Socioeconomic Status ◽  
Low Socioeconomic Status ◽  
Study Group ◽  
Age Group ◽  
Major Health ◽  
Low Socioeconomic ◽  
Medical College ◽  
Prompt Treatment ◽  
Increased Risk ◽  
H Pylori

Background: H. pylori infection is a major health ailment in most of the developing countries. The infection is associated with increasing morbidity and mortality ranging from chronic gastritis to gastric malignancies. The aim of this study is to assess the prevalence of H. pylori among patients tested positive for the same in Saveetha Medical College, Thandalam over the period of 2018-2020 and assess the incidence with factors like socioeconomic status, age and sex of the patients. Objectives: To determine the incidence of pylori for the patients who tested positive for the same over the period of 2018-2020. To assess the patients infected with pylori for various factors like age, sex and socioeconomic status. Materials and Methods: It is a retrospective type of study. The patients who tested positive for H. pylori infection in Saveetha Medical College over the period of 2018-2020 was taken into study. A total of 300 H. pylori infected patients were assessed for various factors like age, sex and socioeconomic status. Results: Out of 300 patients who tested positive for H.pylori were categorized based on age sex and socioeconomic status. Among 300 infected patients, 230 turned out to be men while only 70 cases seen among women. The prevalence was high among the age group > 60 (n=150; 50%) while the 40-60 recorded the second highest number of cases (30% n=90). 20-40 was the least affected group. Most of the cases were associated with low socioeconomic status, alcohol and smoking which contributes to the increased risk of acquiring the H. pylori infection. Conclusion: The incidence of H. pylori infection is high among the study group. Hence it is essential to provide prompt treatment and take adequate measures to prevent the risk factors.

scholarly journals Clinical Pattern of Liver Abscess among the Patients Admitted in Rajshahi Medical College Hospital

2015 ◽  
Vol 26 (2) ◽  
pp. 55-60
Author(s):  
Chanchal Kumar Ghosh ◽  
Fakhrul Alam ◽  
M Mahmuduzzaman ◽  
AKM Shamsul Kabir ◽  
M Saif Uddoula ◽  
...  
Keyword(s):  
Socioeconomic Status ◽  
Liver Abscess ◽  
Low Socioeconomic Status ◽  
Middle Aged ◽  
College Hospital ◽  
Low Socioeconomic ◽  
Clinical Pattern ◽  
Palm Wine ◽  
Medical College ◽  
History Of

Introduction: Liver abscess is an important clinical problem in tropical regions of the world. Current assessment of liver abscesses should allow for better understanding of the aetiopathogenesis of the disease. This study was conducted to find the clinical pattern and aetiopathogenesis of liver abscess in patients admitted in Rajshahi Medical College Hospital.Methodology: The present cross-sectional study was carried out in the Department of Medicine, Rajshahi Medical College Hospital (RMCH) on consecutive 34 patients of liver abscess admitted between the period of July 2002 and June 2003. Detailed history and clinical examination were performed in all patients. All routine investigations were done. Liver abscess was confirmed by ultrasonography (USG). Aspiration of liver abscess was done under sonographic guidance in the Nuclear Medicine Department of RMCH to diagnose the cause of liver abscess. Aspirated materials were sent for microscopical examination and culture and sensitivity in the Department of Microbiology of the same Institute.Result: The findings showed that early middle-aged population were usually affected by liver abscess followed by middle aged (mean age around 40 years). The patients were predominantly male with males being 16 times more likely to suffer from the disease than the females. Most of the patients belong to low socioeconomic status (82.4%). All patients had fever and malaise. Other common manifestations were loss of appetite, lump in the abdomen, intercostal tenderness, nausea/ vomiting, loss of weight. Less common presentations were diarrhoea (29.4%), jaundice (23.5%), cough (11.8%), chest pain (11.8%) and breathlessness (2.9%). Liver span of the patients measured by ultra-sonogram showed hepatomegaly in all cases. All patients with pyogenic liver abscess and 75% of the patients with amoebic abscess had the history of prolonged intake of fermented palm juice (palm wine). Microscopic examination of the pus/aspirate drawn from the liver revealed trophozoite in 7(20.6%) cases. However, on culture of the specimen, 12(35.3%) were culture positive and 22(64.7%) were culture negative.Conclusion: Middle-aged male with low socioeconomic status with the history of prolonged palm wine intake are the most common characteristic of patients with liver abscess. Multi-center study with large sample size is recommended to verify the findings of the present study.Bangladesh J Medicine Jul 2015; 26 (2) : 55-60

Role of Imaging in Pretreatment Evaluation of Early Invasive Cervical Cancer: Results of the Intergroup Study American College of Radiology Imaging Network 6651–Gynecologic Oncology Group 183

2005 ◽  
Vol 23 (36) ◽  
pp. 9329-9337 ◽  
Author(s):  
Hedvig Hricak ◽  
Constantine Gatsonis ◽  
Dennis S. Chi ◽  
Marco A. Amendola ◽  
Kathy Brandt ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Characteristic Curve ◽  
Gynecologic Oncology ◽  
Invasive Cervical Cancer ◽  
Clinical Staging ◽  
Gynecologic Oncology Group ◽  
Reference Standard ◽  
Oncology Group ◽  
Gynecology And Obstetrics ◽  
Ct And Mri

Purpose To compare magnetic resonance imaging (MRI) and computed tomography (CT) with each other and to International Federation of Gynecology and Obstetrics (FIGO) clinical staging in the pretreatment evaluation of early invasive cervical cancer, using surgicopathologic findings as the reference standard. Patients and Methods This prospective multicenter clinical study was conducted by the American College of Radiology Imaging Network and the Gynecologic Oncology Group from March 2000 to November 2002; 25 United States health centers enrolled 208 consecutive patients with biopsy-confirmed cervical cancer of FIGO stage ≥ IB who were scheduled for surgery based on clinical assessment. Patients underwent FIGO clinical staging, helical CT, and MRI. Surgicopathologic findings constituted the reference standard for statistical analysis. Results Complete data were available for 172 patients; surgicopathologic findings were consistent with FIGO stages IA to IIA in 76% and stage ≥ IIB in 21%. For the detection of advanced stage (≥ IIB), sensitivity was poor for FIGO clinical staging (29%), CT (42%), and MRI (53%); specificity was 99% for FIGO clinical staging, 82% for CT, and 74% for MRI; and negative predictive value was 84% for FIGO clinical staging, 84% for CT, and 85% for MRI. MRI (area under the receiver operating characteristic curve [AUC], 0.88) was significantly better than CT (AUC, 0.73) for detecting cervical tumors (P = .014). For 85% of patients, FIGO clinical staging forms were submitted after MRI and/or CT was performed. Conclusion CT and MRI performed similarly; both had lower staging accuracy than in prior single-institution studies. Accuracy of FIGO clinical staging was higher than previously reported. The temporal data suggest that FIGO clinical staging was influenced by CT and MRI findings.

scholarly journals A study on clinicopathological evaluation of rhinosporidiosis

2017 ◽  
Vol 5 (10) ◽  
pp. 4519
Author(s):  
Prangya Panda ◽  
Bijaya Kumar Sadangi ◽  
Dhaneswari Jena ◽  
Sarita Panda
Keyword(s):  
Socioeconomic Status ◽  
Low Socioeconomic Status ◽  
Pond Water ◽  
Lacrimal Sac ◽  
Low Socioeconomic ◽  
Medical College ◽  
Palpebral Conjunctiva ◽  
History Of ◽  
The Common ◽  
Almost All

Background: Rhinosporidiosis is a chronic granulomatous disease. Aim of the study was to do a clinicopathological evaluation of the cases of rhinosporidiosis. Study design was longitudinal.Methods: The study was undertaken in MKCG medical college. 151 cases of rhinosporidiosis were taken. Pedunculated or sessile, fleshy, polypoidal, reddish looking mass with spores on the surface were clinically diagnosed as rhinosporidiosis. Age, sex distribution, site of presentation and socioeconomic status was studied. The swellings of lacrimal sac were doughy in consistency. The conjunctival mass was excised and thermocautery applied. For the cases of lacrimal sac dacryocystectomy was done.Results: The cases were more common in male children of low socioeconomic status. Palpebral conjunctiva is the common site of involvement. History of pond bath was present in almost all the cases. History of bleeding from nose and eye was present in many cases.Conclusions: Rhinosporidiosis is a common condition of our locality. Treatment is simple by excising the growth and cauterising the site. Taking bath in pond water is supposed to be the cause of the disease. The disease can be prevented by avoiding pond bath.

scholarly journals Post Radiotherapy Uro-gynaecological Morbidities in Cancer Cervix-Retrospective Study

KYAMC Journal ◽  
2013 ◽  
Vol 3 (2) ◽  
pp. 273-276
Author(s):  
Mst. Atia Sultana ◽  
Kh. Shahnewaj ◽  
Monira Akhter ◽  
Meher Nigar Sharmin ◽  
Tasneema Rahman Shejuty ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Retrospective Study ◽  
Surgical Treatment ◽  
Patient Selection ◽  
Vaginal Discharge ◽  
Invasive Cervical Cancer ◽  
Genital System ◽  
Cancer Cervix ◽  
Vaginal Stenosis ◽  
Postcoital Bleeding

Aims & Objectives: This study aimed to investigate the complications related to uro-genital system of patients who received radiotherapy for invasive cervical cancer. The patient selection is randomized who were evaluated in OPD Obst. Gynae. Deptt.of KYAMCH after receiving their full course of radiotherapy.100 patients were evaluated. In this study most of the women were perimenopausal, having 2-5 children, most of them were presented with vaginal discharge & postcoital bleeding, most of them received surgical treatment followed by radiotherapy & chemotherapy. During radiotherapy most of them having no complains, some of them were suffering from frequency of micturation & dysuria. 31% patient suffered from dyspareunia, 17% vaginal stenosis, 7% vaginal discharge and 7% cystitis. KYAMC Journal Vol. 3, No.-2, January 2013, Page 273-276 DOI: http://dx.doi.org/10.3329/kyamcj.v3i2.15166

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