Probiotic Attributes of Lactobacillus fermentum NKN51 Isolated from Yak Cottage Cheese and the Impact of Its Feeding on Growth, Immunity, Caecal Microbiology and Jejunal Histology in the Starter Phase of Broiler Birds

2020 ◽  
Author(s):  
Ajit S. Yadav ◽  
Geeta . ◽  
Suchismita Pradhan ◽  
Ravi Rajoria ◽  
Asok Kumar M ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Production Performance ◽  
Lactobacillus Fermentum ◽  
Cottage Cheese ◽  
Great Success ◽  
Meat Industry ◽  
Poultry Production ◽  
Gut Health ◽  
Growth Promoters ◽  
The Impact

Background: The discovery of antibiotics was a great success in control of the pathogenic infections in living beings. In addition, it also played a significant role in upliftment of the meat industry with their use as the growth promoters in the food animals including poultry. However, massive and incorrect use of antibiotics has resulted in the adverse outcome of antibiotic resistance over the years. In order to limit the antibiotic resistance at industry level itself, exploration of the possible alternatives such as probiotics is the need of the hour to replace the antibiotics in poultry industry without compromising the productivity. Hence, the present study was conducted to explore the effects of a novel probiotic bacterium, Lactobacillus fermentum NKN51 on the production performance of the broilers with an aim to replace the antibiotics in poultry production. Methods: In the present study, a total of 128 broiler birds were grouped randomly into four treatment groups which were fed basal diet (BD) along with the different levels of L. fermentum NKN51,viz.,T1 (BD+107cfu/gm), T2(BD+106cfu/gm), T3 (BD+105cfu/gm) and T4 or control (BD only) for a period of 28 days so as to observe the effect of Lactobacillus fermentum NKN51 in the starter phase of the broiler birds in terms of growth, immunity, gut health and physiology. Result: The result revealed that the group of broiler birds supplemented with Lactobacillus fermentum NKN51 at the level of 107cfu/gm of basal feed had significantly better growth performance, cell mediated and humoral immunity, gut health and jejunal histology in terms of villus height, VH:CD ratio and intestinal absorption capacity. Thus, Lactobacillus fermentum NKN51 was found as an ideal probiotic supplement exhibiting better potential in enhancing the efficiency of broiler birds in terms of improved productivity.

Use of antimicrobial alternatives in broilers and their impacts on health and productive performance.

2021 ◽  
Vol 16 (001) ◽  
Author(s):  
Leandro M. Redondo
Keyword(s):  
One Health ◽  
Irreversible Process ◽  
Growth Promotion ◽  
Resistant Bacteria ◽  
Poultry Production ◽  
Productive Performance ◽  
Gut Health ◽  
Growth Promoters ◽  
The One ◽  
The Impact

Abstract Antimicrobials are the keystone of therapy for bacterial infectious diseases. The One Health approach recognizes that the health of humans, animals, and the environment are intricately connected, where the use of antimicrobials in animals select for resistant bacteria which carries resistant genetic elements that can be transmitted from animals to humans. Therefore, antimicrobials use should be limited to treat sick animals. The removal of antimicrobials as growth promoters from animal diets is a growing and irreversible process that led to develop, select, and use cost and effective alternatives in poultry production. The most popular alternatives widely used in several regions of the world include metals, enzymes, organic acids, probiotics, prebiotics, synbiotics, phytochemicals and combinations of them. The expected outcomes in health and productive performances of poultry chickens can be achieved if those antimicrobial alternatives are able to control some factors that influence gut health and productivity. The present review focuses on the impact of most widespread alternatives used for growth promotion on microbiota, immune system, and oxidative status.

scholarly journals Pretreatment with probiotics ameliorate gut health and necrotic enteritis in broiler chickens, a substitute to antibiotics

AMB Express ◽  
2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Danish Sharafat Rajput ◽  
Dong Zeng ◽  
Abdul Khalique ◽  
Samia Sharafat Rajput ◽  
Hesong Wang ◽  
...  
Keyword(s):  
Broiler Chickens ◽  
Production Systems ◽  
Economic Losses ◽  
Necrotic Enteritis ◽  
Poultry Production ◽  
Gut Health ◽  
Growth Promoters ◽  
Broiler Performance ◽  
Antibiotic Growth Promoters ◽  
Microbial Strains

AbstractNecrotic enteritis (NE) is being considered as one of the most important intestinal diseases in the recent poultry production systems, which causes huge economic losses globally. NE is caused by Clostridium perfringens, a pathogenic bacterium, and normal resident of the intestinal microflora of healthy broiler chickens. Gastrointestinal tract (GIT) of broiler chicken is considered as the most integral part of pathogen’s entrance, their production and disease prevention. Interaction between C. perfringens and other pathogens such as Escherichia coli and Salmonella present in the small intestine may contribute to the development of NE in broiler chickens. The antibiotic therapy was used to treat the NE; however European Union has imposed a strict ban due to the negative implications of drug resistance. Moreover, antibiotic growth promoters cause adverse effects on human health as results of withdrawal of antibiotic residues in the chicken meat. After restriction on use of antibiotics, numerous studies have been carried out to investigate the alternatives to antibiotics for controlling NE. Thus, possible alternatives to prevent NE are bio-therapeutic agents (Probiotics), prebiotics, organic acids and essential oils which help in nutrients digestion, immunity enhancement and overall broiler performance. Recently, probiotics are extensively used alternatives to antibiotics for improving host health status and making them efficient in production. The aim of review is to describe a replacement to antibiotics by using different microbial strains as probiotics such as bacteria and yeasts etc. having bacteriostatic properties which inhibit growth of pathogens and neutralize the toxins by different modes of action.

scholarly journals The impact of vitamin E and/or selenium dietary supplementation on growth parameters and expression levels of the growth-related genes in broilers

2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Olla A. Khalifa ◽  
Rasha A. Al Wakeel ◽  
Shabaan A. Hemeda ◽  
Mohamed M. Abdel-Daim ◽  
Ghadeer M. Albadrani ◽  
...  
Keyword(s):  
Health Status ◽  
Vitamin E ◽  
Liver Tissue ◽  
General Health ◽  
Dietary Supplementation ◽  
Production Performance ◽  
Poultry Production ◽  
General Health Status ◽  
Production Parameters ◽  
The Impact

Abstract Background Broilers are continuously stressed because of the rapid growth rate and the environmental issues associated with industrialized poultry production systems, which lead to higher susceptibility for infection with pathogens. It is well known that vitamin E (Vit. E) and selenium (Se) supplementation have protective functions in such stressful conditions. This protocol was to investigate the impact of Vit. E and/or Se on the production performance, some serum biochemistry, and expression of some growth-related gene in the liver tissue of the broilers. The day-old chicks were allotted into four groups according to the supplement; Control group and groups supplemented with Vit. E and/or Se into Vit. E group (100 mg Vit. E/kg diet), Se group (0.3 mg sodium selenite/kg diet), and Vit E + Se group that supplemented with both Vit. E and Se. Results The data of the present experiment showed that dietary inclusion of Vit. E and/or Se significantly (P ≤ 0.05) improved the production parameters without any side effect on the general health status of the broilers, which indicated by normal serum biochemical parameters. Moreover, the treatments positively affected the expression of some genes related to growth performance including growth hormone receptor (GHR) and insulin-like growth factor 1 (IGF1) in the liver tissue of broilers. Conclusion Dietary supplementation of Vit. E and/or Se improved the production parameters and upregulate the growth-related genes without effect on the general health status of the broilers.

scholarly journals Seaweeds, Intact and Processed, as a Valuable Component of Poultry Feeds

2020 ◽  
Vol 8 (8) ◽  
pp. 620
Author(s):  
Izabela Michalak ◽  
Khalid Mahrose
Keyword(s):  
Feed Additives ◽  
Production Performance ◽  
Biologically Active ◽  
Poultry Production ◽  
Waste Biomass ◽  
Growth Promoters ◽  
Active Compounds ◽  
Renewable Biomass ◽  
Poultry Nutrition ◽  
Poultry Feeding

Poultry production is an important area of the agricultural economy. Nowadays, there is an interest in novel sources of feed additives that will improve production performance and poultry health. As an easily available and renewable biomass rich in biologically active compounds, seaweeds can meet this demand. Different forms of seaweeds–seaweed powder from naturally occurring biomass, cultivated or waste biomass, extracted compounds, post-extraction residues or liquid extracts–may be used in poultry feeding. Inclusion of this unconventional material in the poultry nutrition can positively influence the poultry performance along with its health and enrich poultry products with active compounds, such as micro- and macroelements, polyunsaturated fatty acids and pigments. Seaweeds also reduce lipids and cholesterol in eggs. Moreover, due to their unique properties, they can serve as an alternative to antibiotic growth promoters. This review presents the latest developments in the use of seaweeds in poultry nutrition, as well as its limitations.

scholarly journals The Impact of Animal Agriculture on Human Health

2021 ◽  
Author(s):  
Andrea Kassay
Keyword(s):  
Antibiotic Resistance ◽  
Infectious Diseases ◽  
Health Problems ◽  
Human Diseases ◽  
Meat Industry ◽  
Animal Agriculture ◽  
The Us ◽  
Excessive Consumption ◽  
Us Fda ◽  
The Impact

Animal agriculture contributes to many health problems that exist today, such as the spread of infectious diseases, antibiotic resistance, and chronic human diseases like heart disease and cancer. With regards to infectious diseases, most modern day infections were unknown before the domestication of animals. Industrial agriculture forces a large number of genetically similar animals into unsanitary situations, providing the perfect conditions for viruses to emerge and spread to different species. With regards to antibiotic resistance, the US FDA estimates that each year, 80% of microbial drugs are sold to the meat industry. Countries that have the most microbial resistance also have the highest use of antimicrobials, such as penicillins, tetracyclines, and sulfonamides in animal agriculture. With regards to chronic human diseases, there is extensive evidence that the excessive consumption of animal-based products can lead to chronic diseases such as cardiovascular disease and some types of cancer. The purpose of this article is to further discuss how animal agriculture may be a cause of these current health problems and how adopting a plant-based diet can be a potential solution.

129 Maternal Nutrition and in Ovo Feeding Affect Gut Health and Performance of Poultry

2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 68-69
Author(s):  
Rajesh Jha ◽  
Razib Das ◽  
Pravin Mishra
Keyword(s):  
Growth Performance ◽  
Maternal Nutrition ◽  
Nutrient Utilization ◽  
Feed Additives ◽  
Poultry Production ◽  
Limited Information ◽  
Gut Health ◽  
Growth Promoters ◽  
In Ovo ◽  
In Ovo Feeding

Abstract Maintaining a healthy gastrointestinal tract (GIT) is critical for better nutrient utilization, optimum performance, and overall health of poultry. Thus, several nutritional strategies have been tried to improve poultry’s gut health. More recently, different nutrients and feed additives are being used in poultry diets with some success when antibiotic growth promoters (AGP) are not an acceptable option anymore. However, effective modulation of gut health depends on the methods and timing of the compound being available to host animals. Routinely, the alternatives to AGP like prebiotics, probiotics, symbiotic, enzymes, and other nutrients are provided in feed or water to poultry. However, the GIT of the newly hatched poultry is functionally immature, despite going through significant morphological, cellular, and molecular changes toward the end of incubation. Thus, the early growth and development of GIT are of critical importance to enhance nutrients utilization and optimize the growth performance of poultry. Maternal nutrition and in ovo feeding have been used and found to be effective in improving gut health but with inconsistent results. The effects of maternal nutrition on the development and viability of embryo and post-hatch growth performance of birds are documented. However, there is limited information on how maternal nutrition affects the gut health of chicks. In contrast, information on the same from in ovo feeding of nutrients and feed additives has increased in recent years. The results show that in ovo feeding can be a good tool to modulate gut health of post-hatch birds positively. However, more information is needed on the proper route and time of inoculation, optimum doses, and effective combination of different compounds to maximize the benefits of in ovo feeding technique in poultry production.

scholarly journals Overview of Prebiotics and Probiotics: Focus on Performance, Gut Health and Immunity – A Review

2017 ◽  
Vol 17 (4) ◽  
pp. 949-966 ◽  
Author(s):  
Pratima Acharya Adhikari ◽  
Woo Kyun Kim
Keyword(s):  
Growth Performance ◽  
Bacterial Resistance ◽  
Intestinal Bacteria ◽  
Mechanisms Of Action ◽  
Feed Additives ◽  
Poultry Production ◽  
Gut Health ◽  
Growth Promoters ◽  
In Ovo ◽  
Poor Growth

AbstractDue to the threat and emergence of bacterial resistance against antibiotics, the use of in-feed antibiotics at therapeutic and subtherapeutic levels has been limited. Complete withdrawal of antibiotics as growth promoters (AGP) has led to poor gut health signs in chickens that include conditions like wet litter, intestinal bacteria overgrowth, poor growth performance, malabsorption and various diseases. Two of the most common alternatives to AGP are prebiotics and probiotics. Both prebiotics and probiotics have become the potential feed additives that improve the gut health, immune system and microbiota by various mechanisms of action, and enhance growth performance of chickens. The review discusses the modes of action like antibacterial, competitive exclusion (CE), and immunomodulatory properties of prebiotics and probiotics, particularly in poultry.In ovofeeding of prebiotics and probiotics with promising effect on growth performance and reduction of pathogens likeSalmonellais also discussed in this review. However, it is necessary to conduct more research with prebiotics and probiotics as well as other feed additives to understand the detailed mechanisms of action and identify better alternatives for poultry production and health.

scholarly journals The Effect of α-Monolaurin and Butyrate Supplementation on Broiler Performance and Gut Health in the Absence and Presence of the Antibiotic Growth Promoter Zinc Bacitracin

Antibiotics ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 651
Author(s):  
Bakang R. Letlole ◽  
Ellen P. C. W. Damen ◽  
Christine Jansen van Rensburg
Keyword(s):  
Bacterial Resistance ◽  
Feed Additives ◽  
Growth Promoter ◽  
Gut Health ◽  
Feed Conversion ◽  
Growth Promoters ◽  
Broiler Performance ◽  
Positive Effects ◽  
Zinc Bacitracin ◽  
The Impact

The use of antibiotic growth promoters (AGP) is common practice to improve broiler production and performance. The use of AGP is under discussion as it can induce bacterial resistance. The purpose of this study was to determine the impact of removing AGP from broiler feed and study the effect of feed additives. For those countries where in-feed AGP are still permitted, the effect of the products in the presence of AGP was evaluated. Half the number of male broilers received a diet free of AGP, whereas the other half received a diet supplemented with zinc bacitracin at 0.5 g/kg. Both diets were either without additional additives or combined with a coated sodium butyrate, α-monolaurin or a combination of these additives. Raised under optimal conditions, the incorporation of AGP had no effect on broiler performance, but negatively affected villi height and villi height to crypt depth (VH:CD) ratio in the duodenum. In the absence of AGP, butyric acid and α-monolaurin had a positive effect on villi height. In the presence of AGP, α-monolaurin resulted in the lowest feed conversion ratio and improved VH:CD ratio in the duodenum, jejunum and ileum. Both feed additives had minimal effect on performance parameters but showed small positive effects on gut health in the absence of AGP and could play a role in the strategy to replace AGP.

scholarly journals 16S rRNA Sequencing Analysis of the Gut Microbiota in Broiler Chickens Prophylactically Administered with Antimicrobial Agents

Antibiotics ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 146 ◽  
Author(s):  
Matteo Cuccato ◽  
Selene Rubiola ◽  
Diana Giannuzzi ◽  
Elena Grego ◽  
Paola Pregel ◽  
...  
Keyword(s):  
16S Rrna ◽  
Gut Microbiota ◽  
Broiler Chickens ◽  
Antimicrobial Agents ◽  
Alpha Diversity ◽  
Rrna Gene ◽  
Sequencing Analysis ◽  
Poultry Production ◽  
Growth Promoters ◽  
The Impact

In poultry production, gut microbiota (GM) plays a pivotal role and influences different host functions related to the efficiency of production performances. Antimicrobial (AM) use is one of the main factors affecting GM composition and functions. Although several studies have focused their attention on the role of AMs as growth promoters in the modulation of GM in broilers, the consequences of higher AM concentrations administered during prophylactic treatments need to be better elucidated. For this purpose, 16S rRNA gene sequencing was performed to evaluate the impact of different prophylactic AM protocols on the composition and diversity of the broiler GM. Diversity analysis has shown that AM treatment significantly affects alpha diversity in ileum and beta diversity in both ileum and caecum. In ileal samples, the Enterobacteriaceae family has been shown to be particularly affected by AM treatments. AMs have been demonstrated to affect GM composition in broiler. These findings indicate that withdrawal periods were not enough for the restoral of the original GM. Further studies are needed for a better elucidation of the negative effects caused by an altered GM in broilers.

scholarly journals The Effect of Antibiotic Growth Promoters (AGP) on Antibiotic Resistance and the Digestive System of Broiler Chicken in Sleman, Yogyakarta

2021 ◽  
Vol 33 ◽  
pp. 04005
Author(s):  
Tri Untari ◽  
Okti Herawati ◽  
Marla Anggita ◽  
Widya Asmara ◽  
Agnesia Endang Tri Hastuti Wahyuni ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Digestive Tract ◽  
Broiler Chickens ◽  
Broiler Chicken ◽  
Feed Additives ◽  
Public Understanding ◽  
Economic Losses ◽  
Growth Promoters ◽  
Antibiotic Growth Promoters ◽  
The Impact

Chicken is a major source of animal protein consumption in Indonesia. The problem facing the poultry industry is the incidence of resistance which increases mortality of the chicken production. One of the causes of resistance case is the use of antibiotics in feed additives. The public understanding about the effects of the use of antibiotic growth promoters (AGP) in chickens in antibiotic resistance and the digestive tract of chicken needs to be done to avoid the impact on economic losses and health problems. This study aims to provide an understanding of the effects of the use of antibiotic growth promoters (AGP) on antibiotic resistance and the digestive tract of broiler chickens. This study was carried out at a broiler chicken farm in Sleman, Yogyakarta. Based on the histopathological result of the digestive tract of chickens that were given antibiotics as AGP, there was no inflammation occurs, but the administration of antibiotics caused antibiotic resistance in various type of antibiotics including tetracycline (90% resistance), streptomycin (60% resistance), amoxicillin (50% resistance), erythromycin (80% resistance), and no resistance for gentamycin.

Sign in / Sign up

Export Citation Format

Share Document