Results of X-ray endovascular hemostasis in the treatment of malignant neoplasms of the colon and rectum, complicated by bleeding

2016 ◽  
Vol 21 (4) ◽  
pp. 186-189
Author(s):  
Alexey V. Shelekhov ◽  
V. V Dvornichenko ◽  
A. V Munkuev ◽  
R. I Rasulov ◽  
S. I Radostev ◽  
...  

There are present near results of X - ray endovascular hemostasis in patients suffering from malignant neoplasm of rectosigmoid colon and rectum complicated by bleeding. Patients were divided into basic group (n=16) where the X - ray-endovascular hemostasis was performed and control group (17 patients) where the conservative methods of hemostasis were used. For angiography there was used X-raysurgical complex “GE INNOVA 4100” (General Electric, USA) and ”SHIMADZU” (Shimadzu Corporation, Japan). After preformed hemostasis, the patients of the control and basic groups for rectal cancer were undergone to preoperative radiotherapy, then radical surgery, for rectosigmoid cancer - surgical treatment. The quantity, volume of donor blood products in the treatment ofpatients of the control group were used in a significantly greater extent (p

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Claudia Bănescu ◽  
Adrian P. Trifa ◽  
Smaranda Demian ◽  
Erzsebeth Benedek Lazar ◽  
Delia Dima ◽  
...  

The genetic polymorphisms of X-ray repair cross complementing group 1 (XRCC1), X-ray repair cross complementing group 3 (XRCC3), and xeroderma pigmentosum complementation group D (XPD) repair genes may lead to genetic instability and leukemogenesis. The purpose of the study was to evaluate the association betweenXRCC1Arg399Gln, Arg280His and Arg194Trp,XRCC3Thr241Met, andXPDLys751Gln polymorphisms and the risk of developing CML in Romanian patients. A total of 156 patients diagnosed with CML and 180 healthy controls were included in this study. We found no association between CML andXRCC1orXRCC3variant genotypes in any of the investigated cases. A significant difference was observed in the variant genotype frequencies of theXPDLys751Gln polymorphism between the patients with CML and control group (for variant homozygous genotypes,OR=2.37; 95%CI=1.20–4.67;Pvalue = 0.016 and for combined heterozygous and variant homozygous genotypes,OR=1.72; 95%CI=1.10–2.69;Pvalue = 0.019). This was also observed when analyzing the variant 751Gln allele (OR=1.54; 95%CI=1.13–2.11;Pvalue = 0.008). Our results suggest that theXPDLys751Gln variant genotype increases the risk of CML.


PLoS ONE ◽  
2020 ◽  
Vol 15 (12) ◽  
pp. e0243492
Author(s):  
Monika Pierzak ◽  
Aldona Kubala-Kukuś ◽  
Dariusz Banaś ◽  
Ilona Stabrawa ◽  
Jolanta Wudarczyk-Moćko ◽  
...  

Total reflection X-ray fluorescence analysis (TXRF) was used to determine chromium, selenium and bromine concentrations in blood serum samples of 50 patients with parenteral nutrition treatment. The concentrations were measured two times, namely in the first day (I measurement) of the treatment and the seventh day (II measurement) after the chromium and selenium supplementation. For comparison purposes also serum samples of 50 patients without nutritional disorders, admitted to a planned surgical procedure to remove the gall bladder (cholecystectomy), were analyzed and treated as the control group. Descriptive statistics of measured concentrations of Cr, Se and Br both for the studied and control groups was determined. In order to check the effectiveness of Cr and Se supplementation, the results of the first and seventh day measurements for studied group were statistically compared with each other, with literature reference values and with the results of the control group (two-group comparison). These comparisons indicate the effectiveness of selenium supplementation in the applied treatment procedure. In the case of Cr and Br concentrations no statistically significant differences were observed. We conclude that monitoring of the concentration of the important trace elements in human serum should be standard procedure in parenteral nutrition treatment. In this monitoring the TXRF technique can be successfully used.


2020 ◽  
Vol 8 (4_suppl3) ◽  
pp. 2325967120S0028
Author(s):  
Daniel W. Green ◽  
Sreetha Sidharthan ◽  
Lindsay M. Schlichte

Background: Osgood-Schlatter disease (OSD) is a traction apophysitis caused by repetitive strain and chronic avulsion of the secondary ossification center of the tibal tuberosity from the patellar tendon. Purpose: The aim of this study was to determine if OSD is associated with increased posterior tibial slope (PTS). Methods: A total of 40 knees with OSD and 32 control knees examined by the senior author between 2008 and 2019 were included. Patients aged 10 to 15 years old with clinical diagnosis of OSD supported by radiographic findings on lateral X-ray and MRI were eligible. Age- and sex-matched subjects with history of anterior knee pain but no evidence of OSD on clinical exam and no fragmentation of the tibial tubercle on lateral X-Ray and MRI were included in the control group. PTS was defined as the angle between the reference line and a line drawn tangent to the uppermost anterior and posterior edges of the medial tibial plateau. Measurements were carried out in duplicate on true lateral X-Rays by two blinded investigators. Interrater reliability of posterior tibial slope measurements between the two examiners was evaluated using intraclass correlation coefficient (ICC). Independent-sample student t-test was used to compare PTS in the OSD and control knees. Results: Mean age at time of lateral radiograph was 12.6 ± 1.6 years and 51% (37/72) of knees were male. There were no differences in age, sex, and laterality of knees between the OSD and control groups. Mean PTS was significantly higher in the OSD group (12.23º ± 3.58º) compared to the control group (8.82 º ± 2.76 º, p<0.001) (Figure 1). ICC was 0.931 (95% confidence interval, 0.890 to 0.957) for measurement of PTS between the two examiners, indicating almost perfect interrater reliability. Conclusion: This study is the first to identify an association between OSD and increased PTS. The clinical implications of this novel finding have not yet been elucidated. However, several studies have demonstrated that increased PTS is a risk factor for ACL injury and re-tear. It may be speculated in patients with OSD, stress from the extensor mechanism through the patellar tendon loads the anterior portion of the tibia disproportionately to the posterior segment, thereby resulting in asymmetric growth and an increased PTS. [Figure: see text]


2021 ◽  
Vol 26 (2) ◽  
pp. 20-22
Author(s):  
Adeline Larisa Horga

Abstract Procalcitonin is a new generation marker used to differentiate bacterial from viral pneumonia. Although it is not a test routinely used in practice, it can be included in diagnosis and treatment algorithm of pneumonia in children. Studies have shown the effectiveness of procalcitonin in determining of duration of antibiotherapy and hospitalization, too. The test is superior to the other laboratory parameters, compared to reactive C protein, inclusively. Depending on the result of the pulmonary x-ray (bacterial pneumonia) admitted patients were included in: study group – patients with increased values of procalcitonin, and control group – patients with normal values ones. The study proposed a comparative analysis; the correlation index was used to demonstrate how laboratory parameters can interact, and the evolutionary trend of studied parameters was analysed. The results are consistent with the literature data, validating the superiority of procalcitonin in establishing the etiologic diagnosis and the treatment evaluation in bacterial pneumonia in children.


Author(s):  
Sakhin V.T. ◽  
Kryukov E.V. ◽  
Gordienko A.V. ◽  
Pisarevskaya O.N. ◽  
Rukavitsyn O.A.

Relevance. Anemia of chronic diseases has a significant impact on the quality of life of patients with malignant neoplasms, as well as on the course of the underlying disease and prognosis. Aim. To study the characteristics of the secretion of interleukin-1β (IL-1β), interferon-γ (INF-γ) in patients with malignant neoplasms with and without anemia of chronic diseases. To study the effect of these cytokines on hemoglobin synthesis, erythropoiesis and some indicators of iron metabolism. To propose a working version of the classification of anemia of chronic diseases based on the leading pathogenetic factor in the development of anemia. Material and methods. The study involved 42 (27 patients with anemia - 19 men, 8 women, average age 65.1 ± 8.1 years, 15 without it, 10 men, 5 women, average age 61.1 ± 10.1 years) patients with II- Stage IV malignant neoplasm. A comparative analysis was carried out between groups with and without anemia and a correlation analysis between IL-1β, INF-γ and indicators of hemogram, iron metabolism, C-reactive protein (CRP), hepcidin. Results. In patients with malignant neoplasms and ACD, in comparison with patients in the control group, a more pronounced inflammation was proved, accompanied by an increase in the synthesis of ferritin, CRP and IL-1β, INF-γ (p <0.05). For IL-1β, a moderate correlation was found with the concentration of iron (r = 0.46), CST (r = 0.48), hemoglobin (r = -0.61) and a strong correlation with the concentrations of hepcidin (r = 0.8), ferritin (r = 0.78), CRP (r = 0.87). A weak correlation was found between IL-1β and the number of erythrocytes, TIBC and transferrin. For IFN-γ, a moderate correlation was established with erythrocytes (r = -0.68), hemoglobin (r = -0.57), CST (r = -0.57), ferritin (r = 0.57) and a strong correlation connection with CRP (r = 0.83), hepcidin (r = 0.9), transferrin (r = -0.83). A weak correlation has been established between INF-γ and the concentration of iron, TIBC. Conclusions. In patients with malignant neoplasms and ACD, a more pronounced inflammation was proved, accompanied by an increase in the synthesis of ferritin, CRP and IL-1β, INF-γ. The influence of the investigated cytokines on erythropoiesis, synthesis of hemoglobin and hepcidin, and iron metabolism has been proved. This reflects the pleiotropic effect of these cytokines and the complex pathogenesis of ACD in patients with malignant neoplasms, including erythropoiesis disorders, changes in iron metabolism, and increased synthesis of proinflammatory cytokines. A working version of the classification of ACD (with a predominant iron deficiency, with impaired regulatory mechanisms of erythropoiesis, with insufficient production of erythropoietin) has been proposed.


Author(s):  
Henry I. Smith ◽  
D.C. Flanders

Scanning electron beam lithography has been used for a number of years to write submicrometer linewidth patterns in radiation sensitive films (resist films) on substrates. On semi-infinite substrates, electron backscattering severely limits the exposure latitude and control of cross-sectional profile for patterns having fundamental spatial frequencies below about 4000 Å(l),Recently, STEM'S have been used to write patterns with linewidths below 100 Å. To avoid the detrimental effects of electron backscattering however, the substrates had to be carbon foils about 100 Å thick (2,3). X-ray lithography using the very soft radiation in the range 10 - 50 Å avoids the problem of backscattering and thus permits one to replicate on semi-infinite substrates patterns with linewidths of the order of 1000 Å and less, and in addition provides means for controlling cross-sectional profiles. X-radiation in the range 4-10 Å on the other hand is appropriate for replicating patterns in the linewidth range above about 3000 Å, and thus is most appropriate for microelectronic applications (4 - 6).


2010 ◽  
Vol 80 (1) ◽  
pp. 65-73 ◽  
Author(s):  
Pei-Min Chao ◽  
Wan-Hsuan Chen ◽  
Chun-Huei Liao ◽  
Huey-Mei Shaw

Conjugated linoleic acid (CLA) is a collective term for the positional and geometric isomers of a conjugated diene of linoleic acid (C18:2, n-6). The aims of the present study were to evaluate whether levels of hepatic α-tocopherol, α-tocopherol transfer protein (α-TTP), and antioxidant enzymes in mice were affected by a CLA-supplemented diet. C57BL/6 J mice were divided into the CLA and control groups, which were fed, respectively, a 5 % fat diet with or without 1 g/100 g of CLA (1:1 mixture of cis-9, trans-11 and trans-10, cis-12) for four weeks. α-Tocopherol levels in plasma and liver were significantly higher in the CLA group than in the control group. Liver α-TTP levels were also significantly increased in the CLA group, the α-TTP/β-actin ratio being 2.5-fold higher than that in control mice (p<0.01). Thiobarbituric acid-reactive substances were significantly decreased in the CLA group (p<0.01). There were no significant differences between the two groups in levels of three antioxidant enzymes (superoxide dismutase, glutathione peroxidase, and catalase). The accumulation of liver α-tocopherol seen with the CLA diet can be attributed to the antioxidant potential of CLA and the ability of α-TTP induction. The lack of changes in antioxidant enzyme protein levels and the reduced lipid peroxidation in the liver of CLA mice are due to α-tocopherol accumulation.


Author(s):  
Abdullah Farih

The objective of this study is to measure whether there is or not significant effect of teaching reading by utilizing Hot Potatoes software toward students’ reading comprehension of descriptive text. The variables used were the teaching treatment of Hot Potatoes Software as the independent variable and the students’ reading comprehension of Descriptive Text as dependent variable. Then, the research designed was Quasi-experimental design and the presentation of data used was quantitative. The data were obtained from the eleventh grade, of which 28 students were taken as sample. The students are divided into two groups; experiment group consisted of 12 students and control group consists of 16 students. To get the data, the pre-test and post-test were applied and then analyzed using t-test formula. The researcher had concluded that there is Significant effect of Hot Potatoes Software toward the students’ reading comprehension achievement. The result showed that mean of students’ post-test was increased. It is proved by the t-test (8.54) which is higher than t-table (2.05) at level of significance 5%. It means that the alternative hypothesis was accepted and it proved that Hot Potatoes Software had significant effect toward students’ reading comprehension of Descriptive Text


2017 ◽  
Vol 3 (1) ◽  
pp. 76
Author(s):  
Siti Asiyah ◽  
Dwi Estuning Rahayu ◽  
Wiranti Dwi Novita Isnaeni

The needed of Iron Tablet in pregnancy was increase than mother who not pregnant.  That  cause of  high metabolism at the pregnancy for formed of  fetal organ and energy. One of effort for prevent anemia in mother pregnant with giving the Iron tablet and vitamin c. The reason of  this research in 4 June – 11 July 2014 is for compare the effect of  iron tablet suplementation with and without vitamin C toward Hemoglobin level in mother pregnant With Gestational Age Of 16-32 Weeks In Desa Keniten Kecamatan Mojo Kabupaten Kediri. This research method using comparative analytical.  Research design type of Quasy Eksperiment that have treatment group and control group. Treatment group will giving by Iron tablet and 100 mg vitamin C, and control group just giving by iron tablet during 21 days. Population in this research are all of mother pregnant with Gestational Age Of 16-32 Weeks with Sampling technique is  cluster random sampling is 29 mother pregnant. Comparison analysis of  iron tablet suplementation effect with and without vitamin C toward Hemoglobin level in mother pregnant With Gestational Age Of 16-32 Weeks, data analysis using Mann Whitney U-test and the calculated U value (44,5) less than U-table (51). So there was difference of iron tablet suplementation effect with and without vitamin C toward Hemoglobin level in mother pregnant With Gestational Age Of 16-32 Weeks Therefore, the addition of vitamin C on iron intake is needed to increase the uptake of iron tablets. When the amount of iron uptake increases, the reserves of iron in the body will also increase, so as to prevent anemia in pregnant women; Keywords : Iron Tablet (Fe), Vitamin C, Hemoglobin level, Mother Pregnant


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