scholarly journals BLOOD SMEAR PROFILE OF PATIENTS WITH DENGUE HEMORRHAGIC FEVER IN BALI ROYAL HOSPITAL

2021 ◽  
Vol 5 (1) ◽  
pp. 39
Author(s):  
I Made Dwi Mertha Adnyana ◽  
Ni Luh Gede Sudaryati ◽  
A.A Komang Suardana

Background: Each year, dengue hemorrhagic fever has grown. Clinical hematological examinations and blood preparations are used to confirm the diagnosis. Purpose: To detect, assess and characterize dengue hemorrhagic fever blood smear at Bali Royal Hospital. Method: Cross-sectional descriptive observational study-was conducted in April at Bali Royal Hospital on 37 patients with dengue hemorrhagic fever, clinical hematological tests and the manufacture of blood preparations identified using inclusion and exclusion criteria. Platelet counts, hemoglobin levels, hematocrit values, leukocyte counts, clinic degrees, gender and age, and blue plasma lymphocytes, are all used in hematological analyzed by univariate, ANOVA and BNT tests to analyze data. Result: Patients with dengue hemorrhagic fever are mostly toddlers and children (35.13%), women (54.0%), and dengue fever degree I (64.86%) with positive blue plasma lymphocytes (51.36%). Platelet counts, hemoglobin levels, hematocrit values, and leukocyte counts are significantly changed on days 3, 6, and 9, with probability values (p=0.000) less than p=0.01. The findings of the BNT test indicate that the number of platelets and haemoglobin on various days is significantly different (p<0.01), but the hematocrit value and leukocyte calculation are not significantly different (p>0.01). Conclusion: Clinical hematological tests and blood preparations reveal a blood component anomaly in Dengue Haemorragic Fever (DHF) patients at Bali Royal Hospital on days 3, 6, and 9.

2014 ◽  
Vol 1 (2) ◽  
Author(s):  
Restiayuh Patandianan

Abstract : Dengue hemorrhagic fever (DHF) is an infectious disease caused by the dengue virus and transmitted by Aedes mosquitoes. DHF affects children tend to further increase the morbidity and mortality that needed more attention, both clinical symptoms and laboratory results. In laboratory hemoglobin levels and platelet counts normal weight changes corresponding degree of illness. This research was an analytic retrospective with a cross-sectional. Data sources were secondary data from medical records at BLU RSUP Prof. Dr. R. D. Kandou Manado. Samples were obtained 56 patients who met the inclusion criteria DHF of the total population sample of 137 patients. The results of the data obtained is then processed into statistical data using parametric test (Pearson test) for found the relationship between hemoglobin levels with platelet counts with α = 0,05. . It was found that there was no relationship between hemoglobin levels with platelet counts (p=0,097). Conclusion In this study there was no significant correlation between hemoglobin levels with platelet counts in DHF.Keywords: dengue hemorrhagic fever, hemoglobin levels, platelet counts.Abstrak: Demam berdarah dengue merupakan penyakit infeksi yang disebabkan oleh virus dengue dan ditularkan oleh nyamuk Aedes. DBD yang menyerang anak-anak cenderung lebih meningkatkan morbiditas dan mortalitas sehingga diperlukan perhatian lebih, baik pada gejala klinis maupun hasil laboratorium. Pada pemeriksaan laboratorium kadar hemoglobin dan jumlah trombosit biasa mengalami perubahan. Penelitian ini bersifat analitik retrospektif dengan pendekatan cross sectional. Sumber data merupakan data sekunder dari rekam medik Depertemen Ilmu Kesehatan Anak di BLU RSUP Prof. Dr. R. D Kandou Manado. Sampel penilitian diperoleh 56 pasien DBD yang memenuhi kriteria inklusi dari total populasi sampel 137 pasien. Hasil penelitian diuji menggunakan uji parametrik (Uji Pearson), untuk mengetahui hubungan kadar hemoglobin dengan jumlah trombosit dengan α = 0,05. Uji Pearson menunjukkan tidak ada hubungan antara kadar hemoglobin dengan jumlah trombosit (p=0,097). Disimpulkan bahwa tidak ada hubungan antara kadar hemoglobin dengan jumlah trombosit.Kata Kunci: demam berdarah dengue, hemoglobin, trombosit


2019 ◽  
Vol 1 (1) ◽  
pp. 38-44
Author(s):  
Vudhya Ulhaq Kafrawi ◽  
Nadia Purnama Dewi ◽  
Prima Adelin

Dengue Hemorrhagic Fever (DHF) is a disease caused by the dengue virus. The West Sumatra Health Service reported that the city of Padang was the highest city in the incidence of dengue hemorrhagic fever in West Sumatra. It is known that platelet counts and hematocrit levels are important indicators in determining the occurrence of shock and the severity of the disease. This type of research is a descriptive study using a cross sectional design with a retrospective approach, this study was conducted at the Siti Rahmah Islamic Hospital in Padang. The population in this study were all medical record data of patients who had been diagnosed with dengue hemorrhagic fever by a specialist in internal medicine at the Siti Rahmah Islamic Hospital in Padang period 1 January-31 December 2017, as many as 162 people with 62 samples using Simple random sampling technique. Univariate analysis is presented in the form of a frequency distribution       table. Based on the results of the study, it was found that the highest age was early adulthood, which was 69.4% and the highest sex was women, 58.1%. The highest clinical degree is degree 1, which is 58.1%. Most of the patients had platelet counts <100,000 cells / mm3 is 64.5% with an average platelet count of 87,790 cells / mm3. Most of the normal hematocrit levels were 67.7% with an average hematocrit level of 40.45%. Based on degree 1 most with platelet counts <100,000 cells / mm3 which is 55.6%, at degree 2 mostly with platelet counts <100,000 cells / mm3 which is 76.9% and based on degree 1 most hematocrit levels are normal is 63.9 % and at degree 2 most of the normal hematocrit levels are 73.1%.


Animals ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 347
Author(s):  
Emma Strous ◽  
Arne Vanhoudt ◽  
Anja Smolenaars ◽  
Gerdien van Schaik ◽  
Matthijs Schouten ◽  
...  

Platelet and leukocyte count reference intervals (RIs) for cattle differ by age and while adult RIs are known, RIs for calves are studied less. The aims of this observational study are to evaluate variation of platelet counts of Holstein Friesian calves over the first 14 days of life and to propose RIs for platelet and leukocyte counts of Holstein Friesian calves aged 0–60 days. In a longitudinal study, 19 calves were blood sampled 17 times, in the first 14 days of their lives. Blood was collected in a citrate blood tube and platelet counts were determined. We assessed the course of platelet counts. In a field study, 457 healthy calves were blood sampled once. Blood was collected in an EDTA blood tube and platelet and leukocyte counts were determined. The RIs were calculated by the 2.5 and 97.5 percentiles. Platelet counts started to increase 24 h after birth (mean platelet count 381 × 109/L ± 138 × 109/L) and stabilized after five days (mean platelet count 642 × 109/L ± 265 × 109/L). In calves up to six days of age, platelet counts were lower than in calves older than five days. In conclusion, the RIs of platelet and leukocyte counts in calves were wider in range than the RIs for adult cattle, therefore, calf specific RIs for platelet and leukocyte counts should be used. From 6 until 60 days of age, we propose an RI for platelet counts of 287–1372 × 109/L and for the first 60 days of life an RI for leukocyte counts of 4.0–18.9 × 109/L.


2007 ◽  
Vol 47 (4) ◽  
pp. 150 ◽  
Author(s):  
M. Tatang Puspanjono ◽  
Abdul Latief ◽  
Alan R. Tumbelaka ◽  
Sudigdo Sastroasmoro ◽  
Hartono Gunardi

Background Dengue shock syndrome (DSS) mortality is still high.Monitoring of blood lactate level is important to evaluate shock.Objectives The study were to review the difference between bloodlactate level of DSS and that of dengue hemorrhagic fever (DHF),to correlate blood lactate level with hypoxia state as shock riskfactors (PaO 2 , oxygen saturation, and anion gap) and to determinethe cut-off point of blood lactate level to predict shock.Methods The study was carried out at the Department of ChildHealth, Medical School, University of Indonesia, CiptoMangunkusumo Hospital, Jakarta, from January until July 2006.Three mL venous blood specimen was collected from all subjectsfor peripheral blood, blood gasses, serology, and blood lactateexaminations. This study consisted of a retrospective cohort anda cross sectional method. Data were analyzed with Chi-squaretest. Continous data tested using Mann-Whitney method. Toknow the correlation between blood lactate level and shock riskfactors we use logistic regression test.Results In DSS group, 73% shows hyperlactatemia (lactate =2mmol/L). Conversion of lactate means between two groups issignificantly different from day one to day two and three. Therewas a negative correlation between lactate level and pO 2 andoxygen saturation. Oxygen saturation is the only value that hasclinical correlation. Regressions analysis can be applied using Y= 7.05–0.05 X equation. The cut-off point of lactate level asmarker for shock by using ROC curve is 32.015 mmol/L with 70%sensitivity and 83.3% specificity.Conclusions Hyperlactatemia in DSS can be considered as a signfor unappropriate treatment of shock. Blood lactate level can beused as a biochemical marker for tissue hypoxia, to assess severityof the disease, as monitoring of treatment, and has prognosticvalue of DHF cases.


2018 ◽  
Vol 5 (3) ◽  
pp. 383
Author(s):  
Sofa Nutrima Rismawati

ABSTRACTFree Number of larvae (ABJ) in RW 15, Wonokusumo Village is 85%. However, the incidence of Dengue Hemorrhagic Fever (DHF) is still high, ie 17 cases. The high incidence rate of DHF is due to the interaction between host, agent and environment. Host in terms of behavior, dengue virus as an agent and environment derived from the surrounding conditions that can cause and trigger the spread of DHF. The purpose of this research is to analyze the relationship of host and environment behavior to the occurrence of DHF in RW 15. This research using cross sectional design. Random sampling using the guy method. How to calculate the method guy is 10% of the population so that obtained a sample of 78 respondents. Primary data collection technique is done through indepth interview and filling questionnaire. Secondary data collection was obtained from Wonokusumo Puskemas report and report from Surabaya City Health Office. The research was conducted in RW 15. The result of bivariate statistic test showed significant relation between knowledge, attitude, action and environment against DHF incidence with p> α, 0,00> 0,05. The conclusion of this research is that there is host and environment interaction to DHF incidence. Suggestion of this research is procurement of work program every month, independent larvae monitoring movement by society and 3M movement plus every week on Thursday and procurement of training of cadre jumantik about how and regulation of dosage of abate powder according to dose.Keywords: host behavior, environment, disease Dengue Hemorrhagic Fever


2009 ◽  
Vol 49 (5) ◽  
pp. 259
Author(s):  
Hendra Widjaja ◽  
Max F. J. Mantik

Background Thrombocyte and endothelial cells play animportant role in dengue hemorrhagic fever pathogenesis.Thrombomodulin is a part of glycoprotein membrane inendothelial cells. Therefore, thrombomodulin level willincrease if endothelial cells disruption occurs.Objective To acknowledge the correlation between thedegree of dengue hemorrhagic fever and thrombomodulinlevel.Methods This was a cross-sectional study. Subjects werehospitalized pediatric patients with age ranging from oneto 13 year old in pediatric ward at Pro£ Dr. R.D. KandouHospital, Manado, who had fever. Three milliliters of bloodwere taken from vein, and were divided for two tests whichwere routine blood analysis and thrombomodulin analysis.Different data resulted from the dengue hemorrhagic fevergroup were processed, and analyzed statistically using F Testand LSD (least significant difference) test. The relationbetween dengue hemorrhagic fever and thrombomodulinwas analyzed with Spearman correlation coefficient.Results There was a significant result in the difference ofthrombomodulin level on four dengue hemorrhagic fevergroups which were classified according to the severity ofdengue hemorrhagic fever. There was a very significantpositive correlation between the severity of denguehemorrhagic fever and thrombomodulin level in detectingendothelial cells impairment.Conclusion Thrombomodulin level can be used as amarker to detect endothelial cells impairment in denguehemorrhagic fever. Higher grade of dengue hemorrhagicfever will have higher thrombomodulin level.


2018 ◽  
Vol 13 (3) ◽  
pp. 338-344
Author(s):  
Fithria Dyah Ayu Suryanegara ◽  
Suparmi Suparmi ◽  
Ndaru Setyaningrum

Dengue hemorrhagic fever (DHF) has a high incidence rate, especially in the tropical and subtropical area. Various efforts have been made as an attempt to empower the community in PSN-dengue program, but has not yet reached the optimal result. COMBI (Communication for Behavioral Impact) is a dynamic team working to formulate and deliver the message, materials, and appropriate communication media for community problems found by way of a mutually agreed settlement of the problem.Quantitative research was done by cross sectional method to check the water storage containers inside the houses of the respondents. The number of the respondents were 990 male (38.1%), 1612 female (61.9%). Three (0.1%) respondents were aged <17 years, 249 (9.6%) were 17-25 years old, 526 (20.2%) were 26-35 years old, 706 (27.1%) were 36-45 years old, 602 (23.1%) were 46-55 years old, 348 (13.4%) were 56-65 years old, 173 (6.7%) were >65 years old. Most dominant level of education and employment statuses were 1107 (42.5%) high school and 858 (32.9%) were housewives. The average numbers of Larva Free Index in Sleman Regency, Bantul Regency and Yogyakarta municipality were - 75.8%; 70.9%; and 77.3% respectively. The average CI in Yogyakarta municipality was 7.05%, Sleman Regency was 9.68%, and Bantul Regency was 20.86%. The average HI in Yogyakarta municipality was 22.7%, Sleman Regency was 24.13%, and Bantul Regency was 29.02%. This study suggested that the LFI, CI and HI were not in accordance with the target of the Ministry of Health.


2021 ◽  
Vol 13 (1) ◽  
pp. 27-34
Author(s):  
Retno Hestiningsih ◽  
Govinda Restu Syahputra ◽  
Martini Martini ◽  
Sri Yuliawati ◽  
M. Arie Wuryanto ◽  
...  

Sendangmulyo Village is one of the DHF (Dengue Hemorrhagic Fever) endemic areas in Semarang City. Previous studies reported that Aedes spp. active biting at night (nocturnal biting activity) in some areas in Indonesia. This indicates that changes in the blood-sucking behavior of Aedes spp mosquitoes can have an impact on dengue transmission. This research is a descriptive study with a cross-sectional study design. The study was conducted in 64 houses. The mosquito field collection was carried out using the resting mosquito collection method at 18.00-06.00 WIB. Observations of environmental parameters were also carried out to determine the temperature and humidity of the environment around the breeding grounds of Aedes spp. The results showed that there was a change in Aedes spp's blood-sucking activity from 16.00-17.00 WIB to 18.00-20.00 WIB. The distribution of Aedes albopictus in Sendangmulyo Village was 18% of the total Aedes spp. mosquitoes collected with a Resting Rate (RR) value of 0.98%. The average temperature and humidity in the area were 28.6 °C and 77.2%, respectively. This change in blood-sucking activity in Aedes spp has the potential to increase the risk of spreading DHF in Sendangmulyo Village. Dengue Hemorrhagic Fever vector control efforts need to be improved. Abstrak Kelurahan Sendangmulyo merupakan salah satu daerah endemis DBD (Demam Berdarah Dengue) di Kota Semarang. Studi-studi sebelumnya melaporkan bahwa Aedes spp. aktif menggigit pada malam hari (aktivitas menggigit nokturnal) di beberapa daerah di Indonesia. Hal ini mengindikasikan adanya perubahan perilaku menghisap darah nyamuk Aedes spp. dapat berdampak pada penularan dengue. Penelitian ini merupakan penelitian deskriptif dengan desain studi cross sectional. Penelitian dilakukan pada 64 rumah. Koleksi lapangan nyamuk dilakukan dengan metode  koleksi nyamuk istirahat  pada pukul 18.00-06.00 WIB. Pengamatan parameter lingkungan juga dilakukan untuk mengetahui suhu dan kelembaban lingkungan disekitar tempat perkembangbiakan Aedes spp. Hasil penelitian menunjukkan adanya perubahan aktivitas menghisap darah Aedes spp dari pukul 16.00-17.00 WIB menjadi pukul 18.00-20.00 WIB. Sebaran Aedes albopictus di Kelurahan Sendangmulyo adalah  18% dari total nyamuk Aedes spp yang terkoleksi dengan nilai Resting Rate (RR) sebesar 0,98%. Rata-rata suhu dan kelembaban di daerah tersebut masing-masing adalah 28,6 °C dan 77,2%. Perubahan aktivitas menghisap darah pada Aedes spp ini berpotensi meningkatkan risiko penyebaran DBD  di  Kelurahan Sendangmulyo. Upaya pengendalian vektor DBD perlu ditingkatkan.  


Author(s):  
Wahyu Ajisah ◽  
Irnawati Marsaulina ◽  
R. Kintoko Rochadi

Indonesia is a dengue endemic area and it has an epidemic once in 4-5 years. Until now it tends to increase in number of cases as well as its widespread. Researchers investigated that socio-demography, knowledge and attitudes related to dengue disease affecting the participation of housewives in prevention of dengue fever dengue mosquito through questionnaires and interviews. This research was conducted descriptively with cross sectional approach to 72 housewives in sub-district Muara Dua, Lhokseumawe, Aceh, Indonesia using sample purposive sampling process. The relationship between the characteristics of housewives with their involvement in prevention of Dengue Hemorrhagic Fever (DHF) was analyzed using Pearson correlation analysis. More than 75% of respondents live in endemic areas and over 68% of respondents knew that dengue is transmitted through mosquitoes. 50% of respondents knew that 3M (draining the water reservoir, closing the water reservoir and burying the garbage) Plus as DHF prevention but only 37.5% of respondents have applied 3M Plus even though they know that it needs to be continuously done throughout the year especially in the rainy season. The respondents' participation in prevention of DHF disease in moderate category was 50 respondents (69.44%), 9 respondents (12.5%) were categorized as low in participation and only 13 respondents (18.06%) were categorized as very good in participation in the effort to eliminate DHF. There was a highly significant correlation between knowledge and attitude (p <0.01) and there was a significant correlation in education (p <0.05) of housewives with their actions in the prevention of dengue hemorrhagic fever. This reflects the urgent need for advocacy programs in raising awareness of DHF in the community. The nearest inter-sector collaborates with the medical, veterinary, community and local authority sectors to ensure the availability of DHF prevention services besides 3M Plus, also a monitoring officer/home and public health service to undertake health promotion programs of DHF prevention. This is a key element to eliminate deaths from dengue fever which occur every year.


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