scholarly journals Demographic Diversity of Food Intake and Prevalence of Kidney Stone Diseases in Indian Continent

2018 ◽  
Author(s):  
Manalee Guha ◽  
Hritwick Banerjee ◽  
Pubali Mitra ◽  
Madhusudan Das
Keyword(s):  
Food Intake ◽  
Kidney Stone ◽  
Global Economy ◽  
Bone Fractures ◽  
Heart Diseases ◽  
Human Growth ◽  
Good Health ◽  
Idiopathic Hypercalciuria ◽  
Coronary Heart Diseases

Food intake plays a pivotal role of human growth, which necessarily contributes 45% of global economy and wellbeing in general. Consumption of balanced food is elementary for overall good health while a shift of equilibrium can lead to malnutrition, prenatal death, obesity, osteoporosis and bone fractures, coronary heart diseases (CHD), idiopathic hypercalciuria, diabetes and many more. Though CHD, osteoporosis, malnutrition, obesity are being classified thoroughly in the literature, there are fragmented findings in the regime of kidney stone diseases (KSD) and the correlation with food intake therein. KSD associated with hematuria and renal failure poses an increasing threat to the healthcare and global economy while its emergence of Indian populations is being affected with multi-factorial urological disorder resulting from several factors. In this realm, epidemiological, biochemical, macroeconomic situations been portrayed when food intake is also a paramount importance which rarely been forecasted. Hence, in this article we will be reviewing the corollary connotation with diverse food consumption and the efficacy it plays in KSD extrapolating in Indian context.

scholarly journals The Demographic Diversity of Food Intake and Prevalence of Kidney Stone Diseases in the Indian Continent

Foods ◽  
2019 ◽  
Vol 8 (1) ◽  
pp. 37
Author(s):  
Manalee Guha ◽  
Hritwick Banerjee ◽  
Pubali Mitra ◽  
Madhusudan Das
Keyword(s):  
Food Intake ◽  
Kidney Stone ◽  
Global Economy ◽  
Bone Fractures ◽  
Heart Diseases ◽  
Human Growth ◽  
Good Health ◽  
Idiopathic Hypercalciuria ◽  
Coronary Heart Diseases ◽  
Balanced Diet

Food intake plays a pivotal role in human growth, constituting 45% of the global economy and wellbeing in general. The consumption of a balanced diet is essential for overall good health, and a lack of equilibrium can lead to malnutrition, prenatal death, obesity, osteoporosis and bone fractures, coronary heart diseases (CHD), idiopathic hypercalciuria, diabetes, and many other conditions. CHD, osteoporosis, malnutrition, and obesity are extensively discussed in the literature, although there are fragmented findings in the realm of kidney stone diseases (KSD) and their correlation with food intake. KSD associated with hematuria and renal failure poses an increasing threat to healthcare infrastructures and the global economy, and its emergence in the Indian population is being linked to multi-factorial urological disorder resulting from several factors. In this realm, epidemiological, biochemical, and macroeconomic situations have been the focus of research, even though food intake is also of paramount importance. Hence, in this article, we review the corollary associations with the consumption of diverse foods and the role that these play in KSD in an Indian context.

scholarly journals A negatív érzelmek és a szív- és érrendszeri betegségek összefüggései

2018 ◽  
Vol 159 (48) ◽  
pp. 2005-2010
Author(s):  
Piroska Balog
Keyword(s):  
Cardiovascular Diseases ◽  
Cardiovascular Health ◽  
Heart Diseases ◽  
Negative Emotions ◽  
Anger Expression ◽  
Coronary Heart Diseases ◽  
Vital Exhaustion ◽  
Symptoms Of Depression ◽  
European Guidelines

Abstract: With regard to cardiovascular health, the role of negative emotions, particularly that of depression, anxiety, vital exhaustion and hostility has been studied the most widely. Mainly the somatic symptoms of depression and, out of anxiety disorders, generalised anxiety and panic disorder have been linked to cardiovascular diseases. Based on an analysis of interviews of patients having suffered myocardial infarction, it was found that vital exhaustion (a combination of loss of energy, increased irritability, and general demoralization) is a precursor of infarction. Vital exhaustion has proven to contribute to the development of coronary heart diseases, being one of the most important risk factors in both sexes. With regard to hostility, studies show that anger suppression and destructive anger expression (blaming others) are closely linked to a higher incidence of coronary heart diseases. Evidence shows that the relationship between negative emotions and cardiovascular diseases is one of a two-way causality, that is, the presence of a cardiovascular disease may also enhance negative emotions, low heart rate variability playing a crucial role in both diseases. This study also presents interview questions suggested by the European Guidelines (2016) to estimate negative emotions related to coronary heart diseases. Orv Hetil. 2018; 159(48): 2005–2010.

scholarly journals GC-FID and NMR Spectroscopic Studies on Gamma Irradiated Walnut Lipids

2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
Vassilia J. Sinanoglou ◽  
Irini F. Strati ◽  
Katerina Kokkotou ◽  
Dimitra Lantzouraki ◽  
Constantinos Makris ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Profile ◽  
Irradiation Dose ◽  
Heart Diseases ◽  
Juglans Regia ◽  
Spectroscopic Studies ◽  
Protective Role ◽  
Spectroscopic Techniques ◽  
Coronary Heart Diseases

Walnuts have an excellent fatty acid profile, beneficial for coronary heart diseases. A diet rich in walnuts has shown to decrease the total and LDL cholesterol levels as well as lipoprotein levels. In this study, the effects of different doses ofγ-irradiation and different packaging conditions on proximate composition and fatty acid profile of walnuts (Juglans regiaL.) were investigated merging data from different spectroscopic techniques. Walnuts moisture, ash, fat, and protein content as well as fatty acid profile were evaluated immediately after irradiation. GC-FID results showed that SFA increased and MUFA and PUFA decreased with the increase of irradiation dose. Moreover, MUFA/SFA and PUFA/SFA ratios decreasedP<0.05compared to control samples. Furthermore, NMR spectroscopy was implemented to examine possible discrimination patterns based on irradiation dose and packaging. This approach revealed the role of PUFA decrease with the parallel increase of irradiation dose while indicating the protective role of vacuum and MAP compared to air packaging. In conclusion, at irradiation doses of up to 5 kGy, the walnuts retained the nutritional benefits of its fatty acids, in particular MUFA and PUFA. Concerning the different types of packaging, greater stability in the nuts was observed using MAP packaging.

scholarly journals Role of Platelets in the Pathogenicity of Atherosclerosis and Thrombosis in Coronary Heart Diseases

2021 ◽  
Vol 6 (3) ◽  
pp. 96-107
Author(s):  
Abubakar Auwal Nasir ◽  
Erhabor Osaro ◽  
Ibrahim Mohammed ◽  
Ahmed Hamidu Marafa ◽  
Yakubu Abdulrahman
Keyword(s):  
Heart Diseases ◽  
Coronary Heart Diseases ◽  
Cytokines And Chemokines ◽  
Activated Platelets ◽  
Chronic Inflammatory Condition ◽  
Inflammatory Chemokines ◽  
Intimal Layer ◽  
Artery Disease ◽  
Major Mediator

Atherosclerosis is a chronic inflammatory process that results in coronary artery disease, peripheral artery disease and in many cases of stroke. It is a disease that involves multiple inflammatory cytokine which is regarded as the primary underlying cause of cardiovascular diseases (CVD). CVD is the leading cause of death in the developed and developing countries like Nigeria. From pathological perspective, the chronic inflammatory condition of atherosclerosis occurs due to interplay between platelets, monocytes, macrophages. Physiologically platelets play a significant role in coagulation and repair of endothelial injury. Pathologically, studies have shown that activated platelets release multiple inflammatory cytokines and chemokines that serve as positive mediators of atherosclerosis. This chemokine is (RANTES, P-selectin and PF-4). Activated platelet release p-selectin that mediate platelet adhesion and rolling to injured endothelial cell, RANTES trigger the recruitment of monocytes into the sub- endothelium and PF4 promote the differentiation of monocytes into macrophages in the intimal layer of the endothelium which engulf ox-LDL to form FOAM cells. Thus, the aim of this review is to understand and describe the role of activated platelets in atherosclerosis as well as therapeutic target of these platelet inflammatory chemokines which is the major mediator of atherosclerosis in human.

Abstract 16007: Myeloid-specific Deletion in Lipid Phosphate Phosphatase3 (plpp3) Increases Cardiac Inflammation

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Himi Tripathi ◽  
Kazuhiro Shindo ◽  
Renee Donahue ◽  
Erhe Gao ◽  
Andrew J Morris ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Cardiac Remodeling ◽  
Cardiac Tissue ◽  
Heart Diseases ◽  
Inflammatory Cells ◽  
Littermate Control ◽  
Cell Content ◽  
Coronary Heart Diseases ◽  
Lipid Phosphate

Introduction and Hypothesis: Acute myocardial infarction (AMI) is the leading cause of morbidity and mortality worldwide. The innate immune response plays a major role in cardiac remodeling after AMI. Lysophosphatidic acid (LPA), produced by autotaxin (ATX) and degraded by Lipid phosphate phosphatase 3 (LPP3), regulates monocytosis and promotes inflammation. However, the role of LPP3 in post-AMI inflammation is not understood. Here, we investigated the possible role of Myeloid-specific Plpp3 KO mice in cardiac and systemic inflammation and resulting in adverse cardiac remodeling post-MI. Methods and Results: To generate mice with Myeloid-specific Plpp3 deletion , female Plpp3 fl/fl mice were crossed to male Plpp3 mice expressing Cre recombinase under the control of the LysM promoter to generate lysm-plpp3. mice. These mice and their littermate control underwent MI or sham surgery. Inflammatory cell content was assessed using flow cytometry and immunohistochemistry. Cardiac function and scar size were assessed by echocardiography and Mason Trichrome staining, respectively. Increased number of Ly6C hi monocytes (CD45 + /Ly6C/G hi /CD115 hi ) and pro-inflammatory macrophages (CD45 + /F4-80 + /CD11b + ) (CD45 + /F4-80 + /CD86 + ), in cardiac tissue of Cre+LysM mice was observed compared to Cre-fl/fl littermate controls during peak post-MI inflammation, as assessed by flow cytometry ( Fig.1A-C ). This increase in inflammatory cells and inflammation may be the consequence of the significant increase in bone marrow and spleen progenitor cell count and proliferation. Moreover, Cre+LysM mice cardiac functional recovery was also reduced significantly ( Fig. 1D-F ) as assessed by echocardiography. Conclusion: Myeloid-specific Plpp3 deletion increases the deleterious effects of inflammation on the ischemic myocardium and ATX/ LPA signaling could represent a novel therapeutic target for future clinical studies of coronary heart diseases.

scholarly journals Paracellular calcium transport in the proximal tubule and the formation of kidney stones

2019 ◽  
Vol 316 (5) ◽  
pp. F966-F969
Author(s):  
Joshua N. Curry ◽  
Alan S. L. Yu
Keyword(s):  
Proximal Tubule ◽  
Kidney Stones ◽  
Calcium Transport ◽  
Kidney Stone ◽  
Stone Formation ◽  
Idiopathic Hypercalciuria ◽  
Recent Developments ◽  
Calcium Reabsorption ◽  
Kidney Stone Formation

The proximal tubule (PT) is responsible for the majority of calcium reabsorption by the kidney. Most PT calcium transport appears to be passive, although the molecular facilitators have not been well established. Emerging evidence supports a major role for PT calcium transport in idiopathic hypercalciuria and the development of kidney stones. This review will cover recent developments in our understanding of PT calcium transport and the role of the PT in kidney stone formation.

scholarly journals Role of Vitamin E in Boosting the Immunity from Neonates to Elderly

2021 ◽  
Author(s):  
Mariyappan Kowsalya ◽  
Mohan Prasanna Rajeshkumar ◽  
Thangavel Velmurugan ◽  
Kattakgounder Govindaraj Sudha ◽  
Saheb Ali
Keyword(s):  
Vitamin E ◽  
Respiratory Health ◽  
Heart Diseases ◽  
Well Being ◽  
Preterm Neonates ◽  
Vitamin E Deficiency ◽  
Coronary Heart Diseases ◽  
Oxidative Resistance

The vitamin E is a fat-soluble vitamin which occurs as a tocopherol component abundant in humans. The vitamin E supplements in humans and animals have provided numerous health benefits. The vitamin E is rich in antioxidants which slow the aging process and reduce the free radical damage. Vitamin E isoforms play an important role in respiratory health. It is also important in health and well-being of preterm neonates. Vitamin E deficiency in new born includes hemolytic anemia, disease of retina, bronchopulmonary dysplasia. Further, in vitro studies, vitamin E has increased the oxidative resistance and prevents the atherosclerotic plaque. The consumption of vitamin E rich foods reduces coronary heart diseases. This chapter focuses on the treatment of vitamin E deficiency in preterm babies and the role of vitamin E in preventing coronary heart diseases.

scholarly journals ROLE OF MICRONUTRIENTS IN HEART DISEASES

2021 ◽  
pp. 1-5
Author(s):  
NAMRATA KHAIRNAR ◽  
PRASHANT PINGALE ◽  
SUNIL AMRUTKAR
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Older Patients ◽  
Aging Process ◽  
Heart Diseases ◽  
Vitamin B1 ◽  
Selenium Deficiency ◽  
Coronary Heart Diseases

Heart disease is a common occurrence in older patients in the civilized culture, and the rate is predicted to rise as the software advances. Patients with heart disease should be intended to eat a salt-free diet to lose adiposity. Diet is also critical for heart disease patients; those with nutrition deficits have a low deep prognosis. A growing body of research indicates a correlation between heart disease and a lack of micronutrients. Repairable heart disease has been linked to thiamine and selenium deficiency. Micronutrients and heart disease may, nevertheless, have a more moderate association, according to recent research. This article looks at studies that looked at micronutrient consumption, supplement effectiveness, and micronutrient ingestion in heart disease patients, with an emphasis on retinol, ascorbic acid, a fat-soluble vitamin, vitamin B1, other B vitamins, cholecalciferol, folate, iron, and copper. Because aging is the leading cause of coronary heart disease, treatments intended to reduce down the aging process or improving life expectancy are distinctly different from their standards for the treatment of coronary heart disease. Altering risky life decisions which might relate to aging and coronary heart diseases, such as nicotine usage, obesity, and unique lifestyles, is increasingly become part of the quality of practice.

Examining the Effect of Mitochondrial Fission and Fusion Events on the Heart

2017 ◽  
pp. 73-92
Author(s):  
Ashim Malhotra ◽  
Shivani Soni
Keyword(s):  
Heart Failure ◽  
Fusion Proteins ◽  
Growth And Development ◽  
Heart Diseases ◽  
Mitochondrial Fission ◽  
Human Growth ◽  
Cardiovascular Therapy ◽  
Functional Part ◽  
Human Growth And Development

Mitochondria constitute an integral structural and functional part of the cardiac muscle. The heart muscle relies on the mitochondrial production of fatty acids and ATP as sources of energy during different stages of human growth and development. New mitochondria are created from existing ones by a process called mitochondrial biogenesis which involves both fusion and fission events controlled by a bevy of proteins such as Drp1, OPA1, Mfn1, and Mfn2. In this chapter, we examine the role of these mitochondrial fission and fusion proteins in regulating various heart diseases, particularly, reperfusion injury, dilated cardiomyopathy, and heart failure. It is our intent to examine whether any of these proteins may serve as future candidates for cardiovascular therapy.

Potential Uses of Vinegar as a Medicine and Related in vivo Mechanisms

2016 ◽  
Vol 86 (3-4) ◽  
pp. 127-151 ◽  
Author(s):  
Zeshan Ali ◽  
Zhenbin Wang ◽  
Rai Muhammad Amir ◽  
Shoaib Younas ◽  
Asif Wali ◽  
...  
Keyword(s):  
Chemical Structure ◽  
Review Paper ◽  
Heart Diseases ◽  
Folk Medicine ◽  
Active Role ◽  
Current Review ◽  
Different Types ◽  
Positive Effect

While the use of vinegar to fi ght against infections and other crucial conditions dates back to Hippocrates, recent research has found that vinegar consumption has a positive effect on biomarkers for diabetes, cancer, and heart diseases. Different types of vinegar have been used in the world during different time periods. Vinegar is produced by a fermentation process. Foods with a high content of carbohydrates are a good source of vinegar. Review of the results of different studies performed on vinegar components reveals that the daily use of these components has a healthy impact on the physiological and chemical structure of the human body. During the era of Hippocrates, people used vinegar as a medicine to treat wounds, which means that vinegar is one of the ancient foods used as folk medicine. The purpose of the current review paper is to provide a detailed summary of the outcome of previous studies emphasizing the role of vinegar in treatment of different diseases both in acute and chronic conditions, its in vivo mechanism and the active role of different bacteria.

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