Antiviral potential of coconut (Cocos nucifera L.) oil and COVID-19

Background: COVID-19 caused by the novel SARS Coronavirus-2 (SARS-CoV-2) is causing serious blockades in the global public health sphere. In the absence of a powerful antiviral treatment, exploration of plant-based products with antiviral potential has gained interest. Scope and Approach: This commentary presents the prospects of utilizing coconut oil directly or its derivatives such as monolaurin in treating COVID-19 with a special emphasis on their biochemical characteristics features. The potential pitfalls therein and way forward are also highlighted. Keyfindings and conclusions: There are enough research-backed evidences to demonstrate the antiviral capabilities of coconut oil and monolaurin. Possibility of developing a medium chain fatty acid-based nasal spray as a prophylactic or therapeutic is also discussed. Nevertheless, the potential impediments in devising suitable therapeutic models to treat SARS-CoV-2 are presented.

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Physicochemical Properties of Virgin Coconut Oil Extracted from Different Coconut (Cocos nucifera L) Varieties

CORD ◽

10.37833/cord.v37i.440 ◽

2021 ◽

Vol 37 ◽

pp. 1-10

Author(s):

Dilani Hewa Pathirana ◽

Chandi Yalegama ◽

Darshana Jayawardhana Arachige ◽

Malki Senarathne

Keyword(s):

Fatty Acid ◽

Sri Lanka ◽

Antioxidant Capacity ◽

Fatty Acid Profile ◽

Cocos Nucifera ◽

Coconut Oil ◽

Total Phenolic ◽

Virgin Coconut Oil ◽

Phenolic Substances ◽

Cocos Nucifera L

Virgin coconut oil (VCO) is a superior edible oil extracted from fresh coconut (Cocos nucifera L) kernel using mixed coconut varieties without considering the varietal effect. Therefore, this research focuses on the quality evaluation of VCO extracted from four types of coconut varieties, namely Sri lanka Tall×Tall (TT), a tall variety of Gon Thambili (GT), a tall variety of Ran Thambili (RT) and Philippines tall variety of San Ramon (SR). Mature coconuts from each variety were collected from the Bandirippuwa Estate of the Coconut Research Institute, Sri Lanka to extract VCO by cold press oil extraction method. The extractability of VCO from different varieties was investigated. Moisture, free fatty acid (FFA), fatty acid profile (gas chromatography), peroxide value (PV), color (Lovibond scale), total phenolic substances (Galic acid equivalent), antioxidant capacity (α,α-diphenyl-β-picrylhydrazyl, 0.1mM – DPPH method) and sun protection factor (SPF) of VCO extracted from each variety were analyzed. The experiment was conducted as a completely randomized design with three replicates. Data were analyzed using ANOVA using Tukey’s test by MINITAB 17. Oil extractability (58%-59%), FFA (0.04%-0.12%), color (0.43–0.93) and fatty acid profile of VCO did not show variation among varieties. A higher concentration of total phenolic substances was observed in GT (0.24±0.03mg GAE/100g) while antioxidant capacity (857.19±14.99mg/ml) and SPF (8.99±1.26) was rich in RT.

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Life Lessons of the Pandemic ”Covid - 19”

International Journal of Research in Pharmaceutical Sciences ◽

10.26452/ijrps.v11ispl1.2814 ◽

2020 ◽

Vol 11 (SPL1) ◽

pp. 469-471 ◽

Cited By ~ 1

Author(s):

Bhagyashri Vijay Chaudhari ◽

Priya P. Chawle

Keyword(s):

Public Health ◽

Review Article ◽

Public Health Emergency ◽

The Novel ◽

Global Public Health ◽

Strange Situation ◽

Republic Of China ◽

Lifetime History ◽

The People ◽

Life Lessons

“A lesson learned the hard way is a lesson learned for a lifetime.” Every bad situation hurts; however, it sure does teach us something a lesson. In the same manner of a new lesson for Human lifetime, history is observing 'The Novel COVID-19 ’, a very horrible and strange situation created due to fighting with a microscopic enemy. WHO on 11 February 2020 has announced a name for new disease as - 19 and has declared as a global public health emergency and subsequently as pandemic because of its widespread. This began as an outbreak in December 2019, with its in Wuhan, the People Republic of China has emerged as a public health emergency of international concern. is the group of a virus with non-segmented, single-stranded and positive RNA genome. This bad situation of pandemic creates new scenes in the life of people in a different manner, which will be going to be life lessons for them. Such lessons should be kept in mind for the safety of living beings and many more things. In this narrative review article, reference was taken from a different article published in various databases which include the view of different authors and writers on the "Lessons to be from Corona".

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Formulation of Face-Wash from Coconut (Cocos nucifera (L.)) Oil in Ben Tre Province, Vietnam

Key Engineering Materials ◽

10.4028/www.scientific.net/kem.882.183 ◽

2021 ◽

Vol 882 ◽

pp. 183-190

Author(s):

Tran Thi Kim Ngan ◽

Tran Thien Hien ◽

Le Thi Hong Nhan ◽

Xuan Tien Le

Keyword(s):

Cocos Nucifera ◽

Personal Care Products ◽

Coconut Oil ◽

Sulfate Solution ◽

Lauryl Sulfate ◽

Personal Care ◽

Sodium Lauryl Ether Sulfate ◽

Lauryl Ether ◽

Human Care ◽

Cocos Nucifera L

Today, the need for human care and beauty is increasing. The use of personal care products, especially those from nature, has been given special attention by consumers. With diverse features and good effects on the human body, especially the skin, coconut oil is being cared for by many manufacturers. With the aim of diversifying personal care products from coconut oil, this research has initially achieved positive results. Soap saponified as raw soap is considered to have good cleaning effect (better than sodium lauryl sulfate solution (SLS) when diluted to the same concentration). The combination of 10% crude soap and 4% sodium lauryl ether sulfate (SLES) surfactants formulate cleansing products with effective cleansing properties. Ingredients auxiliary cleaners, moisturizing, and softening, antioxidants are added with the appropriate content to improve the disadvantages of raw soap. The personal care products that have been studied have the potential to enter the cosmetic market and attract many consumers.

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Profil Kolestrol Darah Tikus Setelah Pemberian Virgin Coconut Oil Dan Minyak Zaitun

Bioma Berkala Ilmiah Biologi ◽

10.14710/bioma.17.2.102-105 ◽

2015 ◽

Vol 17 (2) ◽

pp. 102

Author(s):

Muhammad Anwar Djaelani

Keyword(s):

Fatty Acid ◽

Olive Oil ◽

Coconut Oil ◽

Chain Fatty Acid ◽

Medium Chain Fatty Acid ◽

Virgin Coconut Oil ◽

Medium Chain

Tingginya kadar kolestrol dalam tubuh menjadi pemicu munculnya berbagai penyakit. Masyarakat berusaha menurunkan kadar kolesterol dalam tubuhnya. Komponen VCO berupa asam lemak jenuh sekitar 90% dan asam lemak tak jenuh sekitar 10%. Asam lemak jenuh VCO didominasi oleh asam laurat. VCO mengandung asam laurat dan asam kaprilat. Keduanya merupakan asam lemak rantai sedang yang biasa disebut Medium Chain Fatty Acid (MCFA). Minyak zaitun atau Olive oil mengandung lemak tak jenuh yang tinggi terutama asam oleat dan polifenol. Polifenol merupakan antioksidan yang dapat mengikat LDL teroksidasi. Penelitian ini bertujuan untuk mengkaji efek asam lemak jenuh yang menggunakan VCO dan efek asam lemak tak jenuh yang menggunakan minyak zaitun terhadap profil kolesterol darah pada tikus putih. Penelitian ini menggunakan Tikus putih jantan sebanyak 25 ekor yang dibagi dalam 5 kelompok perlakuan yaitu P1 adalah kelompok kontrol, P2 kelompok yang diberi VCO 5 mL/kg pakan, P3 kelompok yang diberi VCO 10 mL/kg pakan, P4 kelompok yang diberi minyak zaitun 5 mL/kg pakan dan P5 kelompok yang diberi minyak zaitun 10 mL/kg pakan. Tiap perlakuan diulang sebanyak 5 kali. Perlakuan selama 4 minggu. Variabel yang diamati meliputi kadar Kolesterol total, HDL dan LDL darah tikus. Data yang didapat, dianalisis menggunakan ANOVA. Hasil yang didapat menunjukkan pada perlakuan dengan VCO menunjukkan pengaruh yang tidak signifikan terhadap perubahan ketiga variabel penelitian. Pada perlakuan dengan minyak zaitun kadar HDL tidak terdapat perbedaan yang signifikan antar kelompok perlakuan, kadar Kolesterol total pada kelompok perlakuan menunjukkan penurununan yang tidak signifikan dan kadar LDL pada kelompok perlakuan 10 mL/kg pakan menunjukkan penurununan yang signifikan. Dapat disimpulkan bahwa pemberian VCO tidak berpengaruh pada profil kolestrol darah tikus normolipidemia, dan minyak zaitun berpotensi menimbulkan respon penurunan profil kolesterol tikus pada kadar ≥10 mL/kg pakan. Kata kunci: tikus putih, Kolesterol total, HDL dan LDL, Minyak Zaitun, VCO.

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Coronavirus Pandemic: a major public health crisis for the developed and developing world

The Journal of Infection in Developing Countries ◽

10.3855/jidc.12995 ◽

2021 ◽

Vol 15 (03) ◽

pp. 366-369

Author(s):

Rooh Ullah ◽

Muhammad Suleman Rana ◽

Mehmood Qadir ◽

Muhammad Usman ◽

Niaz Ahmed

Keyword(s):

Public Health ◽

Severe Acute Respiratory Syndrome ◽

Viral Infection ◽

The Novel ◽

Global Public Health ◽

Health Crisis ◽

Public Health Crisis ◽

The World ◽

Novel Coronavirus ◽

Day By Day

Pandemic of novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infections in China is now become global public health crisis. At present 87.64% of the world is infected by this deadly illness. The risk from this epidemic depends on the nature of the virus, including how well it transmits from person to person, and the complications resulting from this current illness. The novel coronavirus has killed thousands of people in China and other countries as well; its rate of mortality is increasing day by day. There is an urgent need to control the virus by developing vaccine or any other antiviral drugs to save the world from this deadly viral infection.

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Extraction of Coconut Oil (Cocos nucifera L.) through Fermentation System

Biodiversitas Journal of Biological Diversity ◽

10.13057/biodiv/d100309 ◽

2009 ◽

Vol 10 (3) ◽

pp. 151-157 ◽

Cited By ~ 12

Author(s):

RINI HANDAYANI

Keyword(s):

Cocos Nucifera ◽

Coconut Oil ◽

Fermentation System ◽

Cocos Nucifera L

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Genes Involved in Lipid Metabolism in Coconut

Innovation in the Food Sector Through the Valorization of Food and Agro-Food By-Products ◽

10.5772/intechopen.90998 ◽

2021 ◽

Author(s):

Wei Xia

Keyword(s):

Fatty Acid ◽

Lipid Metabolism ◽

Lauric Acid ◽

Cocos Nucifera ◽

Evolutionary Relationship ◽

Coconut Oil ◽

Coconut Palm ◽

Acyl Donor ◽

Fatty Acid Accumulation

Coconut palm (Cocos nucifera L) is an economically important monocot plant grown in tropical and subtropical regions. Coconut oil is stored in a solid endosperm and has 47.48–50.5% fatty acid component as lauric acid (C12:0). Present research showed that acyl-acyl carrier protein thioesterases (FatA/B) and lysophosphatidic acid acyltransferase (LAAPT) are key enzymes determining medium-chain fatty acid accumulation in coconut oil. Among five CnFatB genes, CnFatB3 expressed specifically in endosperm and in vitro experiment showed that this gene made mainly lauric acid (C12:0) and tetradecenoic acid (C14:1). Overexpression of CnFatB3 in Arabidopsis increased the amounts of C12:0 and C14:0 in transgenic plant. CnLPAAT gene that is expressed specifically in coconut endosperm showed a preference for using acyl-CoAs containing C10:0, C12:0, and C14:0 acyl groups as acyl-donor substrates. Coconut and oil palm are closely related species with approximately 50% lauric acid (C12:0) in their endosperm. The two species have a close evolutionary relationship between predominant gene isoforms and high conservation of gene expression bias in the lipid metabolism pathways. Moreover, since no stable transformation system has been constructed in coconut palm, gene function validations have been done in vitro, or genes transformed into a heterologous system.

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