QUANDO INDICAR O USO DA FIBRINA RICA EM PLAQUETAS (PRF) NA IMPLANTODONTIA ORAL? - REVISÃO DE LITERATURA

2020 ◽  
Author(s):  
Rodrigo Resende
Keyword(s):  
Low Cost ◽  
Dense Matrix ◽  
Daily Lives ◽  
Platelet Rich Fibrin ◽  
Oral Implants ◽  
Osseointegrated Implants ◽  
Wide Range ◽  
Oral Implant ◽  
Implant Dentistry ◽  
External Trauma

Resumo            Nos últimos anos em todo o mundo, diversas pesquisas científicas realizadas nas áreas de Medicina e Odontologia tem tido como seu tema central à engenharia tecidual envolvendo biomateriais. Essas pesquisas estão sendo realizadas para que possa responder algumas lacunas encontradas no tratamento de lesões relacionados a tecidos moles e duros para uma correta e completa reabilitação dos pacientes. Com isso, os biomateriais enriquecidos com plaquetas ganharam uma maior evidência por estarem proporcionado ótimos resultados no dia a dia da clínica odontológica, em especial na área de implatodontia oral, onde há uma grande necessidade de reabilitar pacientes que sofreram perdas desses tecidos e que se torna imprescindível sua recuperação para um correto posicionamento dos implantes osseointegráveis. A Fibrina Rica em Plaquetas (PRF) é um concentrado, obtido de sangue centrifugado do próprio paciente sem qualquer aditivo, que pode ser considerado um biomaterial de cicatrização autólogo que possui incorporado a ele leucócitos, plaquetas e uma vasta gama de proteínas-chave em uma uma matriz densa de fibrina. As aplicações clínicas deste biomaterial na clínca de implantodontia oral são no prenchimento de alvéolos pós-extração para hemostasia ou associado a enxertos ósseos, levantamento de seio-maxilar ficando em contato direto com a membrana de Schneider, no recobrimento de enxertos instalados sobre alvéolos para que se evite exposição ou traumas externos, dentre outros que auxiliam o dia a dia dos profissionais que trabalham nesta área. Isso com um baixo custo e uma alta taxa de sucesso. O objetivo deste trabalho é realizar uma revisão da literatura demostrando as vantagens e indicações do uso deste biomaterial como auxilio no tratamento de pacientes na clínica de implantodontia oral.Palavras-chave: Fibrina rica em plaquetas; Implantodontia; Biomaterial.Abstract In recent years around the world, several scientific researches carried out in the areas of Medicine and Dentistry have had as their central theme the tissue engineering involving biomaterials. These researches are being conducted to answer some gaps found in the treatment of soft and hard tissue-related injuries for correct and complete rehabilitation of patients. With this, platelet-enriched biomaterials have gained greater evidence because they provide excellent results in daily dental practice, especially in the area of oral implants, where there is a great need to rehabilitate patients who have suffered loss of these tissues. their recovery is essential for the correct positioning of osseointegrated implants. Platelet Rich Fibrin (PRF) is a concentrate obtained from the patient's own centrifuged blood without any additive that can be considered an autologous healing biomaterial that incorporates leukocytes, platelets and a wide range of key proteins into it. a dense matrix of fibrin. The clinical applications of this biomaterial in the oral implant dentistry clinic are in the filling of post-extraction alveoli for hemostasis or associated with bone grafts, sinus-maxillary lift being in direct contact with the Schneider membrane, in the covering of grafts installed over the alveoli so that Avoid exposure or external trauma, among others that help the daily lives of professionals working in this area. This with a low cost and a high success rate. The aim of this paper is to perform a literature review demonstrating the advantages and indications of the use of this biomaterial as an aid in the treatment of patients in the oral implant dentistry clinic. Key-words: Platelet-rich fibrin; Implant dentistry; Biomaterial.

scholarly journals QUANDO INDICAR O USO DA FIBRINA RICA EM PLAQUETAS (PRF) NA IMPLANTODONTIA ORAL? - REVISÃO DE LITERATURA

2020 ◽  
Author(s):  
Rodrigo Resende
Keyword(s):  
Low Cost ◽  
Dense Matrix ◽  
Daily Lives ◽  
Platelet Rich Fibrin ◽  
Oral Implants ◽  
Osseointegrated Implants ◽  
Wide Range ◽  
Oral Implant ◽  
Implant Dentistry ◽  
External Trauma

Resumo            Nos últimos anos em todo o mundo, diversas pesquisas científicas realizadas nas áreas de Medicina e Odontologia tem tido como seu tema central à engenharia tecidual envolvendo biomateriais. Essas pesquisas estão sendo realizadas para que possa responder algumas lacunas encontradas no tratamento de lesões relacionados a tecidos moles e duros para uma correta e completa reabilitação dos pacientes. Com isso, os biomateriais enriquecidos com plaquetas ganharam uma maior evidência por estarem proporcionado ótimos resultados no dia a dia da clínica odontológica, em especial na área de implatodontia oral, onde há uma grande necessidade de reabilitar pacientes que sofreram perdas desses tecidos e que se torna imprescindível sua recuperação para um correto posicionamento dos implantes osseointegráveis. A Fibrina Rica em Plaquetas (PRF) é um concentrado, obtido de sangue centrifugado do próprio paciente sem qualquer aditivo, que pode ser considerado um biomaterial de cicatrização autólogo que possui incorporado a ele leucócitos, plaquetas e uma vasta gama de proteínas-chave em uma uma matriz densa de fibrina. As aplicações clínicas deste biomaterial na clínca de implantodontia oral são no prenchimento de alvéolos pós-extração para hemostasia ou associado a enxertos ósseos, levantamento de seio-maxilar ficando em contato direto com a membrana de Schneider, no recobrimento de enxertos instalados sobre alvéolos para que se evite exposição ou traumas externos, dentre outros que auxiliam o dia a dia dos profissionais que trabalham nesta área. Isso com um baixo custo e uma alta taxa de sucesso. O objetivo deste trabalho é realizar uma revisão da literatura demostrando as vantagens e indicações do uso deste biomaterial como auxilio no tratamento de pacientes na clínica de implantodontia oral.Palavras-chave: Fibrina rica em plaquetas; Implantodontia; Biomaterial.Abstract In recent years around the world, several scientific researches carried out in the areas of Medicine and Dentistry have had as their central theme the tissue engineering involving biomaterials. These researches are being conducted to answer some gaps found in the treatment of soft and hard tissue-related injuries for correct and complete rehabilitation of patients. With this, platelet-enriched biomaterials have gained greater evidence because they provide excellent results in daily dental practice, especially in the area of oral implants, where there is a great need to rehabilitate patients who have suffered loss of these tissues. their recovery is essential for the correct positioning of osseointegrated implants. Platelet Rich Fibrin (PRF) is a concentrate obtained from the patient's own centrifuged blood without any additive that can be considered an autologous healing biomaterial that incorporates leukocytes, platelets and a wide range of key proteins into it. a dense matrix of fibrin. The clinical applications of this biomaterial in the oral implant dentistry clinic are in the filling of post-extraction alveoli for hemostasis or associated with bone grafts, sinus-maxillary lift being in direct contact with the Schneider membrane, in the covering of grafts installed over the alveoli so that Avoid exposure or external trauma, among others that help the daily lives of professionals working in this area. This with a low cost and a high success rate. The aim of this paper is to perform a literature review demonstrating the advantages and indications of the use of this biomaterial as an aid in the treatment of patients in the oral implant dentistry clinic. Key-words: Platelet-rich fibrin; Implant dentistry; Biomaterial.

scholarly journals Platelet analogues in periodontal regeneration: A narrative review

2022 ◽  
Vol 7 (4) ◽  
pp. 211-215
Author(s):  
Vinayaka Ambujakshi Manjunatha ◽  
Ankitha Anil Jadhav ◽  
Chaitanya Sree Chalichamala ◽  
Annavarapu Sahithi ◽  
Harsha Madakaripura Dasegowda
Keyword(s):  
Sports Medicine ◽  
Platelet Rich Plasma ◽  
Periodontal Regeneration ◽  
Preparation Technique ◽  
Time Transfer ◽  
Platelet Rich Fibrin ◽  
Technological Characteristics ◽  
Wide Range ◽  
Implant Dentistry ◽  
Dental Applications

Platelet analogues (PA; platelet rich plasma and platelet rich fibrin) are autologous bioactive compounds that have a wide range of medical and dental applications, including periodontal, maxillofacial, Plastic surgery and sports medicine. The aim of these technologies is to collect all the constituents of a patient's blood sample so that they can be used to promote tissue regeneration and improve healing. Since 1954, PA has come a long way. Periodontology and implant dentistry have both benefited from the use of PAs. However, the non-standard preparation technique, processing time, transfer of concentrates, centrifugation temperature, vibration, etc. are all variables that contribute to the various results described in the literature. This study will retrace the evolution of PAs, their preparation procedures, their clinical and technological characteristics and their uses.

Possession and Repetition

2012 ◽  
Vol 6 (1-3) ◽  
pp. 243-259 ◽  
Author(s):  
Yohan Yoo
Keyword(s):  
First Century ◽  
Daily Lives ◽  
Modern Times ◽  
Sacred Texts ◽  
New Methods ◽  
Wide Range ◽  
Lay Buddhists ◽  
Iconic Status ◽  
And Function ◽  
To Receive

This article demonstrates the need for the iconic status and function of Buddhist scripture to receive more attention by illuminating how lay Korean Buddhists try to appropriate the power of sutras. The oral and aural aspects of scripture, explained by Wilfred Cantwell Smith, provide only a limited understanding of the characteristics of scripture. It should be noted that, before modern times, most lay people, not only in Buddhist cultures but also in Christian and other traditions, neither had the chance to recite scriptures nor to listen to their recitations regularly. Several clear examples demonstrate contemporary Korean Buddhists’ acceptance of the iconic status of sutras and their attempt to appropriate the power and status of those sacred texts. In contemporary Korea, lay Buddhists try to claim the power of scriptures in their daily lives by repeating and possessing them. Twenty-first century lay believers who cannot read or recite in a traditional style have found new methods of repetition, such as internet programs for copying sacred texts and for playing recordings of their recitations. In addition, many Korean Buddhists consider the act of having sutras in one’s possession to be an effective way of accessing the sacred status and power of these texts. Hence, various ways of possessing them have been developed in a wide range of products, from fancy gilded sutras to sneakers embroidered with mantras.

scholarly journals Information and information resources in COVID-19: Awareness, control, and prevention

2021 ◽  
pp. 096100062110165
Author(s):  
Mohammadhiwa Abdekhoda ◽  
Fatemeh Ranjbaran ◽  
Asghar Sattari
Keyword(s):  
Low Cost ◽  
Information Resources ◽  
Age And Gender ◽  
Use Of Resources ◽  
Strategic Approach ◽  
Wide Range ◽  
Data Collection Instrument ◽  
Control And Prevention ◽  
And Gender ◽  
And Control

This study was conducted with the aim of evaluating the role of information and information resources in the awareness, control, and prevention of COVID-19. This study was a descriptive-analytical survey in which 450 participants were selected for the study. The data collection instrument was a researcher-made questionnaire. Descriptive and inferential statistics were used to analyze the data through SPSS. The findings show that a wide range of mass media has become well known as information resources for COVID-19. Other findings indicate a significant statistical difference in the rate of using information resources during COVID-19 based on age and gender; however, this difference is not significant regarding the reliability of information resources with regard to age and gender. Health information has an undisputable role in the prevention and control of pandemic diseases such as COVID-19. Providing accurate, reliable, and evidence-based information in a timely manner for the use of resources and information channels related to COVID-19 can be a fast and low-cost strategic approach in confronting this disease.

scholarly journals Advanced mycelium materials as potential self-growing biomedical scaffolds

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Maria Elena Antinori ◽  
Marco Contardi ◽  
Giulia Suarato ◽  
Andrea Armirotti ◽  
Rosalia Bertorelli ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Low Cost ◽  
Direct Interaction ◽  
Dermal Fibroblasts ◽  
Engineering Systems ◽  
Edible Fungi ◽  
Avant Garde ◽  
Fibrous Network ◽  
Body Tissues ◽  
Wide Range

AbstractMycelia, the vegetative part of fungi, are emerging as the avant-garde generation of natural, sustainable, and biodegradable materials for a wide range of applications. They are constituted of a self-growing and interconnected fibrous network of elongated cells, and their chemical and physical properties can be adjusted depending on the conditions of growth and the substrate they are fed upon. So far, only extracts and derivatives from mycelia have been evaluated and tested for biomedical applications. In this study, the entire fibrous structures of mycelia of the edible fungi Pleurotus ostreatus and Ganoderma lucidum are presented as self-growing bio-composites that mimic the extracellular matrix of human body tissues, ideal as tissue engineering bio-scaffolds. To this purpose, the two mycelial strains are inactivated by autoclaving after growth, and their morphology, cell wall chemical composition, and hydrodynamical and mechanical features are studied. Finally, their biocompatibility and direct interaction with primary human dermal fibroblasts are investigated. The findings demonstrate the potentiality of mycelia as all-natural and low-cost bio-scaffolds, alternative to the tissue engineering systems currently in place.

scholarly journals Rheology and Water Absorption Properties of Alginate–Soy Protein Composites

Polymers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 1807
Author(s):  
Estefanía Álvarez-Castillo ◽  
José Manuel Aguilar ◽  
Carlos Bengoechea ◽  
María Luisa López-Castejón ◽  
Antonio Guerrero
Keyword(s):  
Soy Protein ◽  
Water Solubility ◽  
Divalent Cations ◽  
Low Cost ◽  
Soy Protein Isolate ◽  
Protein Isolate ◽  
Guluronic Acid ◽  
Wide Range ◽  
Anionic Polysaccharides ◽  
Porous Matrices

Composite materials based on proteins and carbohydrates normally offer improved water solubility, biodegradability, and biocompatibility, which make them attractive for a wide range of applications. Soy protein isolate (SPI) has shown superabsorbent properties that are useful in fields such as agriculture. Alginate salts (ALG) are linear anionic polysaccharides obtained at a low cost from brown algae, displaying a good enough biocompatibility to be considered for medical applications. As alginates are quite hydrophilic, the exchange of ions from guluronic acid present in its molecular structure with divalent cations, particularly Ca2+, may induce its gelation, which would inhibit its solubilization in water. Both biopolymers SPI and ALG were used to produce composites through injection moulding using glycerol (Gly) as a plasticizer. Different biopolymer/plasticizer ratios were employed, and the SPI/ALG ratio within the biopolymer fraction was also varied. Furthermore, composites were immersed in different CaCl2 solutions to inhibit the amount of soluble matter loss and to enhance the mechanical properties of the resulting porous matrices. The main goal of the present work was the development and characterization of green porous matrices with inhibited solubility thanks to the gelation of alginate.

scholarly journals Optically transparent and very thin structure against electromagnetic pulse (EMP) using metal mesh and saltwater for shielding windows

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Duy Tung Phan ◽  
Chang Won Jung
Keyword(s):  
Electromagnetic Pulse ◽  
Low Cost ◽  
High Energy ◽  
Metal Plate ◽  
Optical Transparency ◽  
Shielding Effectiveness ◽  
Concrete Wall ◽  
Metal Mesh ◽  
Wide Range ◽  
Optically Transparent

AbstractAn electromagnetic pulse (EMP) with high energy can damage electronic equipment instantly within a wide range of thousands of kilometers. Generally, a metal plate placed inside a thick concrete wall is used against an EMP, but it is not suitable for an EMP shielding window, which requires not only strong shielding effectiveness (SE) but also optical transparency (OT). In this paper, we propose a very thin and optically transparent structure with excellent SE for EMP shielding window application. The proposed structure consists of a saltwater layer held between two glass substrates and two metal mesh layers on the outside of the glass, with a total thickness of less than 1.5 cm. The SE and OT of the structure are above 80 dB and 45%, respectively, which not only meet the requirement of EMP shielding for military purposes but also retain the procedure of good observation. Moreover, the OT of the structure can be significantly improved using only one metal mesh film (MMF) layer, while the SE is still maintained high to satisfy the required SE for home applicants. With the major advantages of low cost, optical transparency, strong SE, and flexible performance, the proposed structure can be considered a good solution for transparent EMP shielding windows.

scholarly journals Photocatalytic three-component asymmetric sulfonylation via direct C(sp3)-H functionalization

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Shi Cao ◽  
Wei Hong ◽  
Ziqi Ye ◽  
Lei Gong
Keyword(s):  
Asymmetric Catalysis ◽  
Organic Synthesis ◽  
Photochemical Reaction ◽  
Low Cost ◽  
Bioactive Molecules ◽  
Atom Economy ◽  
Mild Conditions ◽  
Wide Range ◽  
Unsaturated Carbonyl Compound ◽  
Direct Functionalization

AbstractThe direct and selective C(sp3)-H functionalization of cycloalkanes and alkanes is a highly useful process in organic synthesis owing to the low-cost starting materials, the high step and atom economy. Its application to asymmetric catalysis, however, has been scarcely explored. Herein, we disclose our effort toward this goal by incorporation of dual asymmetric photocatalysis by a chiral nickel catalyst and a commercially available organophotocatalyst with a radical relay strategy through sulfur dioxide insertion. Such design leads to the development of three-component asymmetric sulfonylation involving direct functionalization of cycloalkanes, alkanes, toluene derivatives or ethers. The photochemical reaction of a C(sp3)-H precursor, a SO2 surrogate and a common α,β-unsaturated carbonyl compound proceeds smoothly under mild conditions, delivering a wide range of biologically interesting α-C chiral sulfones with high regio- and enantioselectivity (>50 examples, up to >50:1 rr and 95% ee). This method is applicable to late-stage functionalization of bioactive molecules, and provides an appealing access to enantioenriched compounds starting from the abundant hydrocarbon compounds.

Glycans in scaffold design in tissue reconstruction

2021 ◽  
pp. 088391152199784
Author(s):  
Nipun Jain ◽  
Shashi Singh
Keyword(s):  
Cell Attachment ◽  
Low Cost ◽  
Growth Conditions ◽  
Downstream Signaling ◽  
Cell Carrier ◽  
Wide Range ◽  
Proliferation And Differentiation ◽  
Different Types ◽  
Tissue Reconstruction ◽  
A Cell

Development of an artificial tissue by tissue engineering is witnessed to be one of the long lasting clarified solutions for the damaged tissue function restoration. To accomplish this, a scaffold is designed as a cell carrier in which the extracellular matrix (ECM) performs a prominent task of controlling the inoculated cell’s destiny. ECM composition, topography and mechanical properties lead to different types of interactions between cells and ECM components that trigger an assortment of cellular reactions via diverse sensing mechanisms and downstream signaling pathways. The polysaccharides in the form of proteoglycans and glycoproteins yield better outcomes when included in the designed matrices. Glycosaminoglycan (GAG) chains present on proteoglycans show a wide range of operations such as sequestering of critical effector morphogens which encourage proficient nutrient contribution toward the growing stem cells for their development and endurance. In this review we discuss how the glycosylation aspects are of considerable importance in everyday housekeeping functions of a cell especially when placed in a controlled environment under ideal growth conditions. Hydrogels made from these GAG chains have been used extensively as a resorbable material that mimics the natural ECM functions for an efficient control over cell attachment, permeability, viability, proliferation, and differentiation processes. Also the incorporation of non-mammalian polysaccharides can elicit specific receptor responses which authorize the creation of numerous vigorous frameworks while prolonging the low cost and immunogenicity of the substance.

scholarly journals Burkholderia thailandensis E264 as a promising safe rhamnolipids’ producer towards a sustainable valorization of grape marcs and olive mill pomace

2021 ◽  
Author(s):  
Alif Chebbi ◽  
Massimiliano Tazzari ◽  
Cristiana Rizzi ◽  
Franco Hernan Gomez Tovar ◽  
Sara Villa ◽  
...  
Keyword(s):  
Energy Source ◽  
Olive Oil ◽  
Low Cost ◽  
Carbon Sources ◽  
Burkholderia Thailandensis ◽  
Rhamnolipid Production ◽  
Key Points ◽  
Wide Range ◽  
Long Chain ◽  
Olive Mill

Abstract Within the circular economy framework, our study aims to assess the rhamnolipid production from winery and olive oil residues as low-cost carbon sources by nonpathogenic strains. After evaluating various agricultural residues from those two sectors, Burkholderia thailandensis E264 was found to use the raw soluble fraction of nonfermented (white) grape marcs (NF), as the sole carbon and energy source, and simultaneously, reducing the surface tension to around 35 mN/m. Interestingly, this strain showed a rhamnolipid production up to 1070 mg/L (13.37 mg/g of NF), with a higher purity, on those grape marcs, predominately Rha-Rha C14-C14, in MSM medium. On olive oil residues, the rhamnolipid yield of using olive mill pomace (OMP) at 2% (w/v) was around 300 mg/L (15 mg/g of OMP) with a similar CMC of 500 mg/L. To the best of our knowledge, our study indicated for the first time that a nonpathogenic bacterium is able to produce long-chain rhamnolipids in MSM medium supplemented with winery residues, as sole carbon and energy source. Key points • Winery and olive oil residues are used for producing long-chain rhamnolipids (RLs). • Both higher RL yields and purity were obtained on nonfermented grape marcs as substrates. • Long-chain RLs revealed stabilities over a wide range of pH, temperatures, and salinities

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