scholarly journals Antimicrobial activities of different agents including pyrophyllite against foodborne pathogens: A brief review

2021 ◽  
pp. 189-201
Author(s):  
Aleksandra Bocarov-Stancic ◽  
Jelena Krulj ◽  
Marijana Maslovaric ◽  
Marija Bodroza-Solarov ◽  
Rade Jovanovic ◽  
...  
Keyword(s):  
Foodborne Pathogens ◽  
Metal Ion ◽  
Fungal Pathogens ◽  
Antimicrobial Agents ◽  
Antibacterial Properties ◽  
Antimicrobial Properties ◽  
Antimicrobial Activities ◽  
Biological Origin ◽  
Antibacterial And Antifungal Activities ◽  
Mineral Adsorbents

There has been worldwide an increasing interest and more strict criteria for food/feed safety including absence or reduction of the total number of microorganisms (bacteria, moulds and yeasts). Besides heavy metals, materials of biological origin (plant extracts, bio waste, chitosan etc.), some mineral adsorbents also have antimicrobial properties. There is much information about the antibacterial activity of the modified bentonite, montmoriollonite, smectute, zeolites and antifungal activity of various metal ion-exchanged zeolites and natural mineral clay, but there is almost no information about the antimicrobial properties of pyrophyllite, a monoclinic mineral from the group of phyllosilicates. This work summarizes the recent developments of antimicrobial agents and their application, current research, and trends in the area, highlighting pyrophyllite and its potential applications. Pyrophyllite, an unexploited mineral, possesses antimicrobial properties such as antibacterial and antifungal activities against foodborne pathogens which contributes to the protection of consumer?s health and preservation of the environment. Results from preliminary investigations indicate that pyrophyllite showed antibacterial properties against Escherichia coli, Staphylococcus aureus, Enterococcus faecalis, and antifungal properties against fungal pathogens (Fusarium oxysporum, Phoma glomerata and Rhizoctonia solani). This mineral can also be used for biological control of F. oxysporum in the soil for growing potato.

scholarly journals Isolation and Characterization of Fengycins Produced by Bacillus amyloliquefaciens JFL21 and Its Broad-Spectrum Antimicrobial Potential Against Multidrug-Resistant Foodborne Pathogens

2020 ◽  
Vol 11 ◽  
Author(s):  
Long-Zhen Lin ◽  
Qian-Wang Zheng ◽  
Tao Wei ◽  
Zi-Qian Zhang ◽  
Chao-Fan Zhao ◽  
...  
Keyword(s):  
Foodborne Pathogens ◽  
Fungal Pathogens ◽  
Proteolytic Enzymes ◽  
Gel Filtration ◽  
Antimicrobial Properties ◽  
Multidrug Resistant ◽  
Antimicrobial Activities ◽  
Food Preservation ◽  
Antimicrobial Substance ◽  
Isolation And Characterization

The continuing emergence and development of pathogenic microorganisms that are resistant to antibiotics constitute an increasing global concern, and the effort in new antimicrobials discovery will remain relevant until a lasting solution is found. A new bacterial strain, designated JFL21, was isolated from seafood and identified as B. amyloliquefaciens. The antimicrobial substance produced by B. amyloliquefaciens JFL21 showed low toxicity to most probiotics but exhibited strong antimicrobial activities against multidrug-resistant foodborne pathogens. The partially purified antimicrobial substance, Anti-JFL21, was characterized to be a multiple lipopeptides mixture comprising the families of surfactin, fengycin, and iturin. Compared with commercially available polymyxin B and Nisin, Anti-JFL21 not only could exhibit a wider and stronger antibacterial activity toward Gram-positive pathogens but also inhibit the growth of a majority of fungal pathogens. After further separation through gel filtration chromatography (GFC), the family of surfactin, fengycin, and iturin were obtained, respectively. The results of the antimicrobial test pointed out that only fengycin family presented marked antimicrobial properties against the indicators of L. monocytogenes, A. hydrophila, and C. gloeosporioides, which demonstrated that fengycins might play a major role in the antibacterial and antifungal activity of Anti-JFL21. Additionally, the current study also showed that the fengycins produced by B. amyloliquefaciens JFL21 not only maintained stable anti-Listeria activity over a broad pH and temperature range, but also remained active after treatment with ultraviolet sterilization, chemical reagents, and proteolytic enzymes. Therefore, the results of this study suggest the new strain and its antimicrobials are potentially useful in food preservation for the biological control of the multidrug-resistant foodborne pathogens.

scholarly journals Facile Synthesis of Antimicrobial Aloe Vera-“Smart” Triiodide-PVP Biomaterials

Biomimetics ◽  
2020 ◽  
Vol 5 (3) ◽  
pp. 45 ◽  
Author(s):  
Zehra Edis ◽  
Samir Haj Bloukh
Keyword(s):  
Antimicrobial Agents ◽  
Microstructural Analysis ◽  
Aloe Vera ◽  
Antimicrobial Properties ◽  
Surgical Site Infections ◽  
Halogen Bonding ◽  
Polyglycolic Acid ◽  
Antimicrobial Activities ◽  
One Pot

Antibiotic resistance is an eminent threat for the survival of mankind. Nosocomial infections caused by multidrug resistant microorganisms are a reason for morbidity and mortality worldwide. Plant-based antimicrobial agents are based on synergistic mechanisms which prevent resistance and have been used for centuries against ailments. We suggest the use of cost-effective, eco-friendly Aloe Vera Barbadensis Miller (AV)-iodine biomaterials as a new generation of antimicrobial agents. In a facile, one-pot synthesis, we encapsulated fresh AV gel with polyvinylpyrrolidone (PVP) as a stabilizing agent and incorporated iodine moieties in the form of iodine (I2) and sodium iodide (NaI) into the polymer matrix. Ultraviolet-visible spectroscopy (UV-Vis), Fourier transform infrared spectroscopy (FT-IR), x-ray diffraction (XRD), microstructural analysis by scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS) verified the composition of AV-PVP-I2, AV-PVP-I2-NaI. AV, AV-PVP, AV-PVP-I2, AV-PVP-I2-NaI, and AV-PVP-NaI were tested in-vitro by disc diffusion assay and dip-coated on polyglycolic acid (PGA) sutures against ten microbial reference strains. All the tested pathogens were more susceptible towards AV-PVP-I2 due to the inclusion of “smart” triiodides with halogen bonding in vitro and on dip-coated sutures. The biocomplexes AV-PVP-I2, AV-PVP-I2-NaI showed remarkable antimicrobial properties. “Smart” biohybrids with triiodide inclusions have excellent antifungal and promising antimicrobial activities, with potential use against surgical site infections (SSI) and as disinfecting agents.

Phytochemical Screening, Antimicrobial Activities and Nutritional content of Jatropha Tanjorensis Leaves

2019 ◽  
Vol 1 ◽  
pp. 108-113
Author(s):  
B A Anhwange ◽  
I G Agbidye ◽  
B A Kyenge ◽  
P O Ngbede
Keyword(s):  
Proximate Composition ◽  
Antimicrobial Agents ◽  
Reducing Sugars ◽  
Antimicrobial Properties ◽  
Antimicrobial Activities ◽  
Phytochemical Screening ◽  
Bioactive Components ◽  
Standard Procedures ◽  
Hexane Extracts

The leaves of Jatropha tanjarensis were collected and assessed for their phytochemical compositions and antimicrobial activities using methanolic and hexane extracts as to determine the bioactive components and their effects on microorganisms. Also, the nutritional potential was investigated through the determination of proximate composition using standard procedures. The result of phytochemical screening indicated the presence of saponins, cardiac glycosides, reducing sugars, steroids, alkaloids and flavonoids in methanolic extract, the same observation was recorded in n-hexane extract except that reducing sugars were absent and phlobotannins were present. The antimicrobial activities of the leaves extract show that it have some antimicrobial properties. Results of the proximate composition and mineral analysis revealed that the plant is a good source of fiber and minerals. Therefore, leaves of Jatropha tanjarensisapart from being used as antimicrobial agents, can serve as good sources of fiber and minerals when used as vegetables.

scholarly journals Antimicrobial Ionic Liquids with Fumarate Anion

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Biyan He ◽  
Guangnan Ou ◽  
Changyi Zhou ◽  
Meihong Wang ◽  
Suyan Chen
Keyword(s):  
Ionic Liquids ◽  
Antimicrobial Agents ◽  
Antimicrobial Properties ◽  
Antimicrobial Activities ◽  
Biological Properties ◽  
Research Field ◽  
Potassium Sorbate ◽  
Gravimetric Analysis ◽  
Antimicrobial Drugs ◽  
Active Research

The shortage of new antimicrobial drugs and increasing resistance of microbe to antimicrobial agents have been of some concern. The formulation studies of new antibacterial and antifungal agents have been an active research field. Ionic liquids are known as designed liquids with controllable physical/chemical/biological properties and specific functions, which have been attracting considerable interest over recent years. However, no attention has been made towards the preparation of ionic liquids with antimicrobial activities. In this paper, a new class of ionic liquids (ILs) with fumarate anion was synthesized by neutralization of aqueous 1-butyl-3-methylimidazolium hydroxide with equimolar monoester fumarate and characterized using NMR and thermal gravimetric analysis. The ILs are soluble in water and polar organic solvents and also soluble in the common ILs. The antimicrobial activities of the ILs are more active than commercially available potassium sorbate and are greatly affected by the alkyl chain length. The significant antimicrobial properties observed in this research suggest that the ILs may have potential applications in the modern biotechnology.

scholarly journals Multifunctional Therapeutic Potential of Phytocomplexes and Natural Extracts for Antimicrobial Properties

Antibiotics ◽  
2021 ◽  
Vol 10 (9) ◽  
pp. 1076
Author(s):  
Md. Mominur Rahman ◽  
Md. Saidur Rahaman ◽  
Md. Rezaul Islam ◽  
Md. Emon Hossain ◽  
Faria Mannan Mithi ◽  
...  
Keyword(s):  
Antimicrobial Agents ◽  
Therapeutic Potential ◽  
Antimicrobial Properties ◽  
Antimicrobial Activities ◽  
New Drugs ◽  
Animal Origin ◽  
Multiple Drug ◽  
Common Source ◽  
Phagocytic Cells ◽  
Natural Extracts

Natural products have been known for their antimicrobial factors since time immemorial. Infectious diseases are a worldwide burden that have been deteriorating because of the improvement of species impervious to various anti-infection agents. Hence, the distinguishing proof of antimicrobial specialists with high-power dynamic against MDR microorganisms is central to conquer this issue. Successful treatment of infection involves the improvement of new drugs or some common source of novel medications. Numerous naturally occurring antimicrobial agents can be of plant origin, animal origin, microbial origin, etc. Many plant and animal products have antimicrobial activities due to various active principles, secondary metabolites, or phytochemicals like alkaloids, tannins, terpenoids, essential oils, flavonoids, lectins, phagocytic cells, and many other organic constituents. Phytocomplexes’ antimicrobial movement frequently results from a few particles acting in cooperative energy, and the clinical impacts might be because of the direct effects against microorganisms. The restorative plants that may furnish novel medication lead the antimicrobial movement. The purpose of this study is to investigate the antimicrobial properties of the phytocomplexes and natural extracts of the plants that are ordinarily being utilized as conventional medications and then recommended the chance of utilizing them in drugs for the treatment of multiple drug-resistant disease.

Phytochemical Analysis and Antimicrobial Activities of Atalantia monophylla (L) Correa and Atalantia racemosa Wight and Arn

2019 ◽  
Vol 15 (4) ◽  
pp. 427-436
Author(s):  
Mahadevan Subramaniyan ◽  
Vijayakumar Subramaniyan ◽  
Arulmozhi Praveenkumar
Keyword(s):  
Fungal Pathogens ◽  
Leaf Extract ◽  
Antimicrobial Properties ◽  
Antimicrobial Activities ◽  
Diffusion Method ◽  
Phytochemical Analysis ◽  
Root Bark ◽  
Human Pathogens ◽  
Microdilution Method ◽  
Isolation And Characterization

Background: Infectious diseases are major leading cause of death in all parts of the world, because of the appearance of new multi drug resistant microbes. Therefore, the discovery of potential drug for effective treatment will help the slaughter of the microbes. The aim of the present study is to evaluate the presence of photochemical and antimicrobial activities of various crude extracts of leaves, fruits and root bark of Atalantia monophylla and Atalantia racemosa against human pathogens by using well diffusion method. Methods: Antimicrobial properties of the various extracts of Atalantia monophylla and Atalantia racemosa were studied against some human pathogenic microbes such as Gram-positive Bacteria, (Bacillus subtilis, Bacillus cereus, Staphylococcus aureus) Gram-negative Bacteria (Klebsiella pneumoniae, Pseudomonas aeruginosa, Escherichia coli) and human opportunistic fungal pathogens (Candida albicans and Aspergillus niger). All the extracts were comparable with standard drugs (Ciprofloxacin, Gentamicin, Nystatin. and Amphotericin B). Minimum inhibitory concentration (MIC), minimum bactericidal /fungicidal concentration (MBC/MFC) values were determined through a microdilution method. The phytochemical analysis of these plant extracts were carried out using standard mthods. Results: Methanolic leaf extract of A. monophylla has showed excellent antimicrobial activity against S. aureus (40mm). As well, the A. racemosa methanolic leaf extract shows notable inhibitory activity against S. aureus (38mm). At the same time, the least inhibition was observed in aqueous extract of A. monophylla against E.coli (9mm). The MIC ranged from 0.78 µg/mL to 50 µg/mL and MBC/MFC 1.56 to 50 µg/mL were recorded. Phytochemical analysis of alkaloids, steroids, saponins, flavonoids, tannins, terpenoids, phenolics and cardiae glycoside were recorded in various extracts of A. monophylla and A. racemosa respectively. Flavonoids, phenolics and cardiac glycoside were present only in methonalic leaf extract of A. monophylla. Conclusion: The result of this study concluded that methanolic leaf extract has possessed novel compounds with significant antimicrobial properties. Hence, we recommend this plant for further studies on the isolation and characterization of that lead antimicrobial potential molecule.

Antimicrobial Evaluation, Molecular Docking and ADME Properties of Indole Amide Derivatives

2021 ◽  
Vol 18 ◽  
Author(s):  
Derya Doğanay ◽  
Sevval M. Özcan ◽  
Ahmet M. Şentürk ◽  
Süreyya Ölgen
Keyword(s):  
Molecular Docking ◽  
In Silico ◽  
Bacterial Infections ◽  
Antimicrobial Agents ◽  
Antimicrobial Properties ◽  
Antimicrobial Activities ◽  
In Vitro Tests ◽  
Lipinski’S Rule ◽  
Amide Derivatives

Background: Besides the viral infections, bacterial infections can cause serious and life-threatening complications and drug resistance is an important problem to fight bacterial infections. Therefore, it is important to discover novel antimicrobial agents to fight such infections. Objective: Several indole containing antimicrobial drug development studies have been reported in literature that provided strong evidences for good antimicrobial activities against a variety of microorganisms. Taken into consideration from these findings, antimicrobial properties of previously synthesized 16 indole amide derivatives were evaluated by in vitro tests against 14 different microorganisms, and also molecular docking and in silico prediction studies were used to identify structure-activity relationship of compounds. Methods: Antimicrobial activity of compounds was determined by disc diffusion and tube dilution methods. Molecular docking of compounds was studied to determine the relationship between the structure of compounds with DNA gyrase interactions of microorganisms by using the version of Autodock vina 4.2.6. Mol inspiration and Swiss ADME prediction online software programs were also used to identify drug-like properties of compounds. Results: The results showed that some compounds exhibited quite pronounced antibacterial and antifungal activities compared to reference drugs. These results were also supported by molecular docking studies and in silico ADME calculations presented that all tested compounds obey the Lipinski’s Rule of Five and are metabolized by CYP450 enzymes. Conclusion: It can be concluded that these results can be taken as reference in the development of new indole-based antimicrobial agents.

scholarly journals SYNTHESIS, CHARACTERIZATION AND IN VITRO ANTIMICROBIAL EVALUATION OF SOME NOVEL BENZIMIDAZOLE DERIVATIVES BEARING HYDRAZONE MOIETY

2017 ◽  
Vol 10 (16) ◽  
pp. 1
Author(s):  
Jayanta Sarma ◽  
Gurvinder Singh ◽  
Mukta Gupta ◽  
Reena Gupta ◽  
Bhupinder Kapoor
Keyword(s):  
Antibacterial Properties ◽  
Antimicrobial Properties ◽  
Aromatic Aldehydes ◽  
Antibacterial Activities ◽  
Antimicrobial Activities ◽  
Benzimidazole Derivatives ◽  
E Coli ◽  
Antimicrobial Evaluation ◽  
Antibacterial Potential

Objective: The synthesis of novel benzimidazole-hydrazone derivatives has been carried out based on the previous findings that both these pharmacophores possess potent antimicrobial activities. The antibacterial properties of synthesized derivatives were screened against both Gram-positive and Gram-negative bacteria.Methods: O-phenylenediamine on condensation with substituted aromatic acids in polyphosphoric acid gave benzimidazole nucleus which on reaction with ethyl chloroacetate and hydrazine hydrate in two different steps resulted in the formation of substituted acetohydrazides. The targeted compounds 6a-l were synthesized by reaction of substituted acetohydrazides with aromatic aldehydes and screened for their antibacterial potential by cup-plate method.Results: The synthesized benzimidazole-hydrazones exhibited moderate to strong antibacterial activities against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, and Pseudomonas aeruginosa. The compounds 6a-6f were found to be most effective against S. aureus, E. coli, and P. aeruginosa. Among all the synthesized compounds, the zone of inhibition of 6f in highest concentration, i.e., 100 μg/ml were found to be >31 mm against all the stains of bacteria.Conclusion: The antibacterial results revealed that the synthetized derivatives have significant antimicrobial properties and further structure activity relationship studies may develop more potent and less toxic molecules.

scholarly journals Antibacterial Composite Layers on Ti: Role of ZnO Nanoparticles

2016 ◽  
Vol 61 (1) ◽  
pp. 213-216
Author(s):  
A. Roguska ◽  
A. Belcarz ◽  
P. Suchecki ◽  
M. Andrzejczuk ◽  
M. Lewandowska
Keyword(s):  
Zno Nanoparticles ◽  
Antibacterial Properties ◽  
Antimicrobial Properties ◽  
Antimicrobial Activities ◽  
Bacterial Cells ◽  
Metallic Oxide ◽  
Moderate Amount ◽  
Orthopaedic Infections ◽  
Composite Layers ◽  
Biomedical Coatings

Problem of Post-operative infections of implant materials caused by bacterial adhesion to their surfaces is very serious. Enhancement of antibacterial properties is potentially beneficial for biomaterials value. Therefore, the metallic and metallic oxide nanoparticles attract particular attention as antimicrobial factors. The aim of this work was to create nanotubular (NT) oxide layers on Ti with the addition of ZnO nanoparticles, designed for antibacterial biomedical coatings. Antimicrobial activities of titanium, TiO2NT and ZnO/TiO2NT surfaces were evaluated against bacterial strain typical for orthopaedic infections: S. epidermidis. TiO2NT alone killed the free bacterial cells significantly but promoted their adhesion to the surfaces. The presence of moderate amount of ZnO nanoparticles significantly reduced the S. epidermidis cells adhesion and viability of bacterial cells in contact with modified surfaces. However, higher amount of loaded nanoZnO showed the reduced antimicrobial properties than the medium amount, suggesting the overdose effect.

scholarly journals Antibacterial Composite Layers on Ti: Role of ZnO Nanoparticles

2016 ◽  
Vol 61 (2) ◽  
pp. 937-940 ◽  
Author(s):  
A. Roguska ◽  
A. Belcarz ◽  
P. Suchecki ◽  
M. Andrzejczuk ◽  
M. Lewandowska
Keyword(s):  
Zno Nanoparticles ◽  
Antibacterial Properties ◽  
Antimicrobial Properties ◽  
Antimicrobial Activities ◽  
Bacterial Cells ◽  
Metallic Oxide ◽  
Moderate Amount ◽  
Orthopaedic Infections ◽  
Composite Layers ◽  
Biomedical Coatings

Abstract Problem of post-operative infections of implant materials caused by bacterial adhesion to their surfaces is very serious. Enhancement of antibacterial properties is potentially beneficial for biomaterials value. Therefore, the metallic and metallic oxide nanoparticles attract particular attention as antimicrobial factors. The aim of this work was to create nanotubular (NT) oxide layers on Ti with the addition of ZnO nanoparticles, designed for antibacterial biomedical coatings. Antimicrobial activities of titanium, TiO2 NT and ZnO/TiO2 NT surfaces were evaluated against bacterial strain typical for orthopaedic infections: S. epidermidis. TiO2 NT alone killed the free bacterial cells significantly but promoted their adhesion to the surfaces. The presence of moderate amount of ZnO nanoparticles significantly reduced the S. epidermidis cells adhesion and viability of bacterial cells in contact with modified surfaces. However, higher amount of loaded nanoZnO showed the reduced antimicrobial properties than the medium amount, suggesting the overdose effect.

Sign in / Sign up

Export Citation Format

Share Document