scholarly journals The effect of denture cleansing solution (H2O2) on the water solubility of self-cured acrylic resin

2018 ◽  
Vol 30 (3) ◽  
pp. 163
Author(s):  
Irsan Ibrahim ◽  
Prima Luthfia ◽  
Widuri Julia Aryani

Introduction: Denture cleanser must be able to remove bacterial plaque layers, eliminate food debris, with non-toxic properties. Denture cleansing was performed by immersing the denture into a solution of H2O2. Continuous denture wear can lead to plaque accumulation of Candida albicans colonies thus causes denture stomatitis. There was a slight dimensional stability difference of the self-cured acrylic base compared to the heat-cured after immersion in water. This study was aimed to analyse the effect of denture cleansing solution (H2O2) on the water solubility of self-cured acrylic resin. Methods: Twenty-four specimens of self-cured acrylic resin sized 15 x 20 x 2 mm, were divided into the control group (n = 12) and the treatment group (n = 12). All specimens were then immersed in the aquadest (control group) and H202(treatment group) for 6, 8, and 10 hours consecutively. Result: The average water solubility of self-cured acrylic resin soaked in H2O2 solution at 6 hours was 0.0007 µg/mm3; at 8 hours was 0.0011 µg/mm3; and at 10 hours was 0.0013 µg/mm3. The average water solubility of self-cured acrylic resin soaked in aquadest solution at 6 hours was 0.0013 µg/mm3; at 8 hours was 0.0080 µg/mm3; and at 10 hours was 0.0125 µg/mm3. Conclusion: The water solubility of the self-cured acrylic resin immersed in the H2O2 solution for 6, 8, and 10 hours was still below the ISO standard.Keywords: Self-cured acrylic resin, H2O2, immersion time, water solubility.

Polymers ◽  
2022 ◽  
Vol 14 (2) ◽  
pp. 230
Author(s):  
Salwa Omar Bajunaid ◽  
Bashayer H. Baras ◽  
Michael D. Weir ◽  
Hockin H. K. Xu

Denture stomatitis is a multifactorial pathological condition of the oral mucosa that affects up to 72% of denture wearers. It is commonly seen on the palatal mucosa and characterized by erythema on the oral mucosa that are in contact with the denture surface. The aim of this study was to incorporate 2-methacryloyloxyethyl phosphorylcholine (MPC) and dimethylaminohexadecyl methacrylate (DMAHDM) into a high impact polymethylmethacrylate heat-cured denture base acrylic resin as a potential treatment for denture stomatitis. We used a comparative study design to examine the effect of incorporating MPC as a protein repellent agent and DMAHDM as an antifungal agent to prevent the adherence of Candida albicans to the denture base material. The dual incorporation of MPC and DMAHDM reduced C. albicans biofilm colony-forming unit by two orders of magnitude when compared to the control group devoid of the bioactive agents. Although the addition of MPC and DMAHDM alone or in combination significantly reduced the flexural strength of the material, they showed reduced roughness values when compared to control groups. This new denture acrylic resin provides the benefit of enhancing C. albicans biofilm elimination through dual mechanisms of action, which could potentially reduce the prevalence of denture stomatitis.


2013 ◽  
Vol 14 (1) ◽  
pp. 80-83 ◽  
Author(s):  
Naveen S Yadav ◽  
Teerthesh Jain ◽  
Amrita Pandita ◽  
SMA Feroz ◽  
UK Kartika ◽  
...  

ABSTRACT Aim The purpose of this study was to evaluate and compare the flexural strength of commercially available acrylic (trevalone) and modified polymethylmethacrylate (PMMA). Materials and methods Four groups were tested; Group 1— control group regular MMA, group 2—2% methacrylic acid, 88% MMA, group 3—16% methacrylic acid, 84% MMA group 4— 20% methacrylic acid, 80% MMA 15 resin specimens of each group were polymerized. After processing, the specimens were subjected for flexural strength testing using three point bending test in a Universal Testing Machine. All data was statistically analyzed with one-way ANOVA, differences within the groups were analyzed by Scheffe's analysis. Results As the ratio of incorporated methacrylic acid to PMMA increased, the flexural strength decreased. Analysis of data revealed a significant decrease in flexural strength of specimens (p < 0.000) after incorporation of 12%, 16%, 20% methacrylic acid to heat polymerized acrylic resin, when compared with the control group. Lowest flexural strength was observed with specimens containing 20% methacrylic acid and highest flexural strength was observed with specimens containing conventional monomer without methacrylic acid. Conclusion It was observed that as the concentration of methacrylic acid in heat polymerized acrylic resin increases, the flexural strength decreases. Lowest flexural strength was observed with specimens containing 20% methacrylic acid and highest flexural strength was observed with specimens containing conventional monomer without methacrylic acid. Clinical significance The major advantages of addition of methacrylic acid to polymethylmethacrylate could be for the elderly people with restricted manual dexterity or cognitive disturbances, especially for patients who do not follow an adequate denture cleansing protocol and diabetic patients who are more susceptible for denture stomatitis. How to cite this article Jain T, Yadav NS, Pandita A, Feroz SMA, Kartika UK, Singh PP. A Comparative Evaluation of Flexural Strength of Commercially Available Acrylic and Modified Polymethylmethacrylate: An in vitro Study. J Contemp Dent Pract 2013;14(1):80-83.


2020 ◽  
Vol 16 (2) ◽  
pp. 61-63
Author(s):  
Kadek Ayu Wirayuni ◽  
◽  
Sintha Nugrahini

Accumulation of plaque and food scraps on an acrylic resin base will increase bacterial colonies and C. albicans which will cause denture stomatitis. Maintenance of denture hygiene using mechanical, chemical and combination of two methods. Basil leaf extract contain essential oils which are important in fight against resistant C. albicans biofilms. The purpose of this study was to determine the comparison of C. albicans colonies after cleaning various denture cleaning methods. The method of this study is used an experimental method, the study design is posttest only with control group design. Sample size of heat-cured acrylic resin plate is 40x12x3mm. this study use Kruskall-Wallis test and Mann-Whitney test as data analysis for comparison tests between groups (non-parametric test). The results showed that there were significant differences between the various cleansing methods used in reducing C. albicans colonies. The compotition of flavonoids basil leaf extract is anti-microbial which can prevent the entry of fungi that harm the body.


2015 ◽  
Vol 3 (2) ◽  
pp. 68-73
Author(s):  
Riezka Hanafiah Putri ◽  
Zulkarnain Agus ◽  
Eni Rahmi

Heat-polymerized  acrylic  resins  is  the  most  used  denture  base  material  in  prosthodontics.  One  of  mechanical properties of acrylic resins is transverse strength. It represents the masticatory pressure that is applied to denture base. Black tea is the second largest consumed beverage in the world. The aim of this study was to investigate the effect of black tea beverage on transverse strength of heat-polymerized acrylic resins. A total of 24 heat-polymerized acrylic resin plates (65×10×2,5 mm) were immersed in black tea beverage for 1, 4, and 20 days as treatment group and in aquadest for 1, 4, and 20 days as control group. The transverse strength of  acrylic samples were measured by three–point bending test by universal testing machine. Data were statistically analyzed using Independent t test. The transverse strength values of acrylic resin immersed in black tea beverage had no significant differences to the transverse strength values of acrylic resin immersed in aquadest with similar immersion time (p>0,05). There was no effect of black tea beverage on transverse strength of heat-polymerized acrylic resins. Immersion time decrease the transverse strength of heat-polymerized acrylic resins due to water sorption. Keywords: Heat-polymerized acrylic resins, black tea, transverse strength


e-GIGI ◽  
2013 ◽  
Vol 1 (2) ◽  
Author(s):  
Christian Dama

Resin akrilik sering digunakan sebagai bahan dari gigi tiruan, khususnya basis gigi tiruan. Adanya rongga-rongga mikro pada akrilik menjadi tempat perlekatan sisa-sisa makanan yang dapat meningkatkan jumlah mikroorganisme dalam rongga mulut, salah satunya ialah jamur Candida albicans. Pertumbuhan yang pesat dari jamur Candida albicans menjadi penyebab utama infeksi pada mukosa rongga mulut pemakai gigi tiruan lepasan akrilik, disebut denture stomatitis. Ekstrak kayu manis yang mengandung minyak atsiri, sinamaldehid, eugenol dan juga senyawa seperti flavonoid, Saponin, serta tanin memiliki efek antifungi. Tujuan penelitian ini untuk mengetahui pengaruh dari ekstrak kayu manis dan konsentrasi ekstrak kayu manis terhadap jumlah blastospora Candida albicans pada plat akrilik sehingga mampu mencegah dan menanggulangi penyakit denture stomatitis. Plat akrilik yang telah terkontaminasi dengan jamur Candida albicans direndam dalam ekstrak kayu manis dengan konsentrasi 20%, 30%, 40%, 50%, dan aquades sebagai kontrol. selanjutnya, plat akrilik di getarkan untuk menjatuhkan Candida albicans dalam tabung reaksi dan dihitung jumlah blastosporanya dengan metode pengenceran menggunakan cairan NaCl dan metode hitung langsung pada mikroskop. Hasil perhitungan statistik dengan uji Independent t-test diketahui terdapat perbedaan yang bermakna antara kelompok ekstrak kayu manis dan kelompok kontrol (p ≤ 0,05). Dari hasil penelitian dapat disimpulkan bahwa ekstrak kayu manis dapat memengaruhi pertumbuhan jumlah blastospora Candida albicans pada plat resin akrilik dan meningkat seiring dengan meningkatnya konsentrasi ekstrak kayu manis (cinnamomum burmanii) yang digunakan.Kata kunci: Resin akrilik, Candida albicans, ekstrak kayu manis.ABSTRACTAcrylic resin is often used as an ingredient of artificial teeth, denture base in particular. The existence of micro cavities in acrylic attachment to place leftover food that can increase the number of microorganisms in the oral cavity, one of which is Candida albicans. The rapid growth of Candida albicans is a main cause of infection in the oral mucosa acrylic removable denture wearers, called denture stomatitis. Cinnamon extract that contains essential oils, sinamaldehid, eugenol and also compounds such as flavonoids, saponins, and tannins have antifungal effects. The purpose of this study to determine the effect of cinnamon extract and cinnamon extract concentrations against Candida albicans blastospora number on acrylic plate so as to prevent and control disease denture stomatitis. Acrylic plate that has been contaminated with Candida albicans soaked in cinnamon extract with a concentration of 20%, 30%, 40%, 50%, and sterile water as a control. furthermore, acrylic plate vibrate to drop Candida albicans in a test tube and counted the number of blastospora by using saline dilution method and direct count method on the microscope. The results of calculations with the statistical test known Independent t-test significant difference between cinnamon extract group and the control group (p ≤ 0,05). From the results of this study concluded that cinnamon extract may affect the growth of Candida albicans blastospora on acrylic resin plate and increases with increasing concentration of the extract of cinnamon (Cinnamomum burmanii) were used.Keywords : Acrylic resin, Candida albicans, cinnamon extract.


Materials ◽  
2021 ◽  
Vol 14 (5) ◽  
pp. 1067
Author(s):  
Salwa O. Bajunaid ◽  
Bashayer H. Baras ◽  
Abdulrahman A. Balhaddad ◽  
Michael D. Weir ◽  
Hockin H. K. Xu

Candida albicans (C. albicans) biofilm is a common etiological factor in denture stomatitis. The purpose of this study was to investigate the effects of incorporating 2-methacryloyloxyethyl phosphorylcholine (MPC) as a protein repellent into a new high-impact denture acrylic (HIPA) resin on the surface roughness, solution pH, and C. albicans biofilm adhesion to the denture base. The new acrylic denture resin base was formulated by mixing MPC into HIPA resin at mass fractions of 1.5%, 3%, and 4.5%. Surface roughness was measured using a Mitutoyo surface roughness tester. C. albicans biofilm growth and viability were assessed via colony forming unit counts. The pH of the biofilm growth medium was measured using a digital pH meter. Adding MPC to the HIPA resin at percentages of 1.5% and 3% increased the roughness values significantly (p < 0.05), while adding 4.5% MPC resulted in no difference in roughness values to that of the control group (p > 0.05). All experimental groups demonstrated neutral pH values (pH ≅ 7) and were not significantly different from each other (p > 0.05). Incorporating 2-methacryloyloxyethyl phosphorylcholine at 4.5% resulted in a significant (≅1 log) colony-forming unit reduction compared with the control group with 0% MPC (p < 0.05). A fungal-retarding denture acrylic resin was developed through the incorporation of MPC for its protein-repelling properties. This newly developed denture acrylic material has the potential to prevent oral microbial infections, such as denture stomatitis.


2021 ◽  
Vol 11 ◽  
Author(s):  
Ming Feng ◽  
Huanhuan Wang ◽  
Zhiyuan Zhu ◽  
Bowen Yao ◽  
Yongfei Li ◽  
...  

Long-term endocrine treatment which results in estrogen deprivation causes chronic stress associated with a series of uncomfortable symptoms leading not only to a decrease in quality of life but also to cancer recurrence, which may be mediated primarily through the enhanced expression of angiogenic factors, as well as a series of inflammatory microenvironmental changes that favor tumor progression. In this study, we designed a clinical trial and aimed to explore the effects of Sanhuang Decoction (SHD) treatment on chronic stress, inflammatory factors, and breast cancer recovery. A total of 90 patients with breast cancer who met the inclusion/exclusion criteria were randomly allocated to a treatment or control group. The treatment group received the standard endocrine treatment and the traditional Chinese medicine decoction known as SHD. The control group received the standard endocrine treatment only. The treatment period was 6 months. The modified Kupperman Menopausal Index, the self-rating anxiety scale, and the self-rating depression scale were evaluated once per month. The body microenvironment plasma indices related to chronic stress, such as oxidative and antioxidative stress markers, inflammatory factors, hemorheology, coagulation, lipid and D-dimer, immunologic functions, tumor biomarkers, and angiogenic factors of the vascular endothelial growth factor (VEGF) were measured before and after 6 months of treatment. After treatment for 5 months, the scores in the treatment group decreased to nearly normal levels and the control group showed no significant improvement. After treatment for 6 months, all indices related to the body microenvironment, as well as the tumor biomarkers and carcinoembryonic antigen, carbohydrate antigen 153, and angiogenic factor VEGF levels improved significantly to normal levels in the treatment group. Our primary research showed that treatment with SHD effectively improved the quality of life of breast cancer patients by facilitating a change in the body microenvironment that controlled tumor growth and prevented drug resistance.Clinical Trial RegistrationChinese Clinical Trial Registry, identifier ChiCTR-IIR-2000041413. Date of registration: 2017-06-07 (retrospective registration).


1998 ◽  
Vol 20 (3) ◽  
pp. 300-310 ◽  
Author(s):  
Vicki Ebbeck ◽  
Sandra L. Gibbons

This study investigated the effectiveness of a Team Building Through Physical Challenges (TBPC; Glover and Midura, 1992) program on the self-conceptions of physical education students in Grades 6 and 7. The treatment group was exposed to one TBPC activity every second week for 8 months, while the second group completed the regular physical education curriculum without any TBPC activities. Data were analyzed using 2 (treatment/control) x 2 (preintervention/postintervention) x 2 (male/female) repeated measures analysis. Results at postintervention revealed that both male and female students in the treatment group were significantly higher on perceptions of global self-worth, athletic competence, physical appearance, and social acceptance than the control group. Female students in the treatment group were also significantly higher on perceptions of scholastic competence and behavioral conduct than female students in the control group. Effect sizes indicated that meaningful as well as significant differences in self-conceptions were created by the TBPC program.


2020 ◽  
Vol 5 (2) ◽  
pp. 86
Author(s):  
Ardhianing Hardita ◽  
Titik Ismiyati ◽  
Endang Wahyuningtyas

Denture base material should have a good level of biocompatibility. Acrylic resin is frequently used as a denture base material, however it has a disadvantage of producing residual monomer. Residual monomer is known to have a cytotoxicity effect. Titanium dioxide (TiO2) nanoparticles are used as fillers due to their biocompatibility and ability to enhance the mechanical properties of acrylic resin. The addition of the material to acrylic resin could affect the amount of residual monomer. The aim of this study was to examine the effect of the addition of TiO2 nanoparticles as acrylic resin denture base filler on the cytotoxicity in fibroblast cells. The samples consisted of 24 heat cured acrylic resins in disc shape (5 mm in diameter and 2 mm in thickness), divided into 4 groups (n = 6): three groups given treatment with0.5%, 1%, 2% TiO2, respectively and one control group. Cell viability was measured with MTT assay. The results were tested with one way ANOVA with 95% confidence level followed by LSD post hoc test. The results showed that the highest percentage of cell viability was found in the treatment group of 0.5% TiO2 with value of 91.83 ± 1.75%, while the lowest value was seen in the treatment group of 2% TiO2 with value of 79.38 ± 3.34%. Significant differences were shown between the treatment groups of 0.5% and 2% TiO2, as well as between the control and treatment group with 2% TiO2. The conclusions of this research are the addition of TiO2 nanoparticles as acrylic resin denture base filler has an effect on cytotoxicity; the addition of 0.5% TiO2 nanoparticles filler results in lower cytotoxicity on fibroblast cells compared to the addition of 1% and 2% TiO2.  


2017 ◽  
Vol 24 (8) ◽  
pp. 1096-1104 ◽  
Author(s):  
Yael Goverover ◽  
Nancy Chiaravalloti ◽  
Helen Genova ◽  
John DeLuca

Background: Difficulties in learning and memory are among the most persistent and frequently reported cognitive symptoms in individuals with multiple sclerosis (MS). Objective: To examine the efficacy of the self-generation learning program ( self-GEN trial) that consist of behavioral intervention sessions, teaching self-generation technique while using metacognitive strategies to improve learning and memory abilities in persons with MS. Additionally, the treatment aimed to address generalization of the treatment to activities of daily living. Methods: This double-blind, placebo-controlled, randomized clinical trial included 35 participants with clinically definite MS, 19 in the treatment group and 16 in the placebo control group. Participants completed a baseline neuropsychological assessment, including questionnaires assessing everyday memory and a repeat assessment immediately post-treatment. Results: The treatment group showed significantly improved learning and memory, self-regulation, and metacognition relative to the placebo post-treatment. Similar results were noted on measures of depression, functional status, and quality of life (QOL). Conclusion: This study provides initial Class I evidence that the self-GEN behavioral intervention improves memory, self-regulation, functional status, affective symptomatology, and QOL in patients with MS.


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