scholarly journals 20% Citric Acid its effectiveness as a chelator in endodontic treatment of temporary teeth

2021 ◽  
Vol 31 (1) ◽  
pp. 4-9
Author(s):  
JE Orellana-Centeno ◽  
Keyword(s):  
Informed Consent ◽  
Citric Acid ◽  
Antimicrobial Effect ◽  
Pediatric Dentistry ◽  
Endodontic Treatment ◽  
Periapical Lesion ◽  
Colony Forming Units ◽  
Oxygenated Water ◽  
Study Population ◽  
Age Range

In endodontics, the use of a final irrigantthat has properties such as antimicrobial effect, tissue dissolution and biocompatibility is essential, since toxins are the main cause of the development and persistence of a pulp and periapical lesion. Objective: To evaluate the antimicrobial capacity of 20% citric acid as a chelating solution used during the treatment of pulpectomies in temporary dental organs. Materials and methods: The study population included 30 patients from the Pediatric Dentistry Clinical of the Facultad de Estomatologia of the Universidad Autonoma de San Luis Potosí (UASLP). The participants had an age range between 3 to 9 years of age and in terms of gender 15 male and 15 female, after information consent of the minors and signature of the informed consent of the parents. Results: Citric acid at 20% showed a reduction of microorganisms from 2.5 to 6.0 CFU (Colony Forming Units) while oxygenated water, although presenting a reduction for colony forming units, was only 1 to 2 UFC. Conclusion: Citric acid is a good irrigant, but it should continue studies.

Outcome of Patch Test on Crack Sole among Bangladeshi Population

2020 ◽  
Vol 7 (2) ◽  
pp. 64-67
Author(s):  
Abu Sayeed Mohammad ◽  
Shahadat Hossain ◽  
Zulfiqur Hossain Khan
Keyword(s):  
Patch Test ◽  
Clinical History ◽  
Significant Morbidity ◽  
Exclusion Criteria ◽  
Study Population ◽  
Bangladeshi Population ◽  
One Year ◽  
Medical University ◽  
Age Range ◽  
Test Result

Background: Crack sole may produce significant morbidity among the physical labourer. Objective: The purpose of this study was to find out the patch test result in crack sole which was due to allergic contactants. Methodology: This test was conducted in the Department at Dermatology and Venereology of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from July 2001 to June 2002 for a period of one year. Patients with crack sole were selected as study population. All patients were asked about the details clinical history. Patch test was done by individually prepared alminium Finn Chamber mounted on scanpore tape. Result: A total number of 15 patients were recruited for this study after fulfilling the inclusion and exclusion criteria. The age range was 8 years to 70 years. Among 15 patients 3 patients were patch test positive remaining 12 patients were patch test negative. Two patient were female and one was male. Conclusion: In conclusion patch test is positive among the crack sole patients. Journal of Current and Advance Medical Research 2020;7(2): 64-67

scholarly journals In Vitro Effect of Photodynamic Therapy with Different Lights and Combined or Uncombined with Chlorhexidine on Candida spp.

Pharmaceutics ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1176
Author(s):  
Vanesa Pérez-Laguna ◽  
Yolanda Barrena-López ◽  
Yolanda Gilaberte ◽  
Antonio Rezusta
Keyword(s):  
Photodynamic Therapy ◽  
Light Emitting Diode ◽  
Antimicrobial Effect ◽  
Photodynamic Treatment ◽  
Candida Spp ◽  
Promising Alternative ◽  
Light Emitting ◽  
Colony Forming Units ◽  
Vitro Effect

Candidiasis is very common and complicated to treat in some cases due to increased resistance to antifungals. Antimicrobial photodynamic therapy (aPDT) is a promising alternative treatment. It is based on the principle that light of a specific wavelength activates a photosensitizer molecule resulting in the generation of reactive oxygen species that are able to kill pathogens. The aim here is the in vitro photoinactivation of three strains of Candida spp., Candida albicans ATCC 10231, Candida parapsilosis ATCC 22019 and Candida krusei ATCC 6258, using aPDT with different sources of irradiation and the photosensitizer methylene blue (MB), alone or in combination with chlorhexidine (CHX). Irradiation was carried out at a fluence of 18 J/cm2 with a light-emitting diode (LED) lamp emitting in red (625 nm) or a white metal halide lamp (WMH) that emits at broad-spectrum white light (420–700 nm). After the photodynamic treatment, the antimicrobial effect is evaluated by counting colony forming units (CFU). MB-aPDT produces a 6 log10 reduction in the number of CFU/100 μL of Candida spp., and the combination with CHX enhances the effect of photoinactivation (effect achieved with lower concentration of MB). Both lamps have similar efficiencies, but the WMH lamp is slightly more efficient. This work opens the doors to a possible clinical application of the combination for resistant or persistent forms of Candida infections.

scholarly journals Quantitative and functional evaluation of endothelial progenitor cells in patients with cardiac amyloidosis

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
O Itzhaki Ben Zadok ◽  
D Leshem-Lev ◽  
T Ben-Gal ◽  
A Hamdan ◽  
N Schamroth-Pravda ◽  
...  
Keyword(s):  
Progenitor Cells ◽  
Endothelial Progenitor Cells ◽  
Mtt Assay ◽  
Cardiac Amyloidosis ◽  
Microvascular Dysfunction ◽  
Functional Evaluation ◽  
Endothelial Progenitor ◽  
Colony Forming Units ◽  
Study Population ◽  
And Function

Abstract Background Endothelial microvascular dysfunction is a known mechanism of injury in cardiac amyloidosis (CA), but evidence regarding the level and function of endothelial progenitor cells (EPCs) in patients with CA is lacking. Methods Study population included patients with light-chain or transthyretin (ATTR) CA. Patients with diagnosed heart failure and preserved ejection fraction (HFpEF) without monoclonal gammopathy and a 99mTc-DPD scan incompatible with TTR were used as controls. Blood circulating EPCs were assessed quantitatively by the expression of VEGFR-2(+), CD34(+) and CD133(+) using flow cytometry, and functionally by the formation of colony forming units (CFUs). MTT assay was used to demonstrate cell viability. Tests were repeated 3 months following the initiation of amyloid-suppressive therapies (either ATTR-stabilizer or targeted chemotherapy) in CA patients. Results Our preliminary cohort included 14 CA patients (median age 74 years, 62% ATTR CA). Patients with CA vs. patients with HFpEF (n=8) demonstrated lower expression of CD34(+)/VEGFR-2(+) cells [0.51% (IQR 0.4, 0.7) vs. 1.03% (IQR 0.6, 1.4), P=0.043] and CD133(+)/VEGFR-2(+) cells [0.35% (IQR 0.23, 0.52) to 1.07% (IQR 0.6, 1.5), P=0.003]. Functionally, no differences were noted between groups. Following the initiation of amyloid-suppressive therapies in CA patients, we observed the up-regulation of CD34(+)/VEGFR-2(+) cells [2.47% (IQR 2.1, 2.7), P<0.001] and CD133(+)/VEGFR-2(+) cells [1.38% (IQR 1.1, 1.7), P=0.003]. Moreover, functionally, active EPCs were evident microscopically by their ability to form colonies (from 0.5 CFUs [IQR 0, 1.5) to 2 CFUs (IQR 1, 3.5), P=0.023]. EPCs' viability was demonstrated by an MTT assay [0.12 (IQR 0.04, 0.12) to 0.24 (IQR 0.16, 0.3), p=0.014]. Conclusions These preliminary results demonstrate reduced EPCs levels in CA patients indicating significant microvascular impairment. Amyloid-targeted therapies induce the activation of EPCs, thus possibly promoting endothelial regeneration. These findings may represent a novel mechanism of action of amyloid-suppressive therapies EPCs in CA patients and during therapy Funding Acknowledgement Type of funding source: None

scholarly journals Awareness and Attitudes toward Corneal Donations among Applicants and Staff of a Driver, Vehicle and Licensing Authority (DVLA) in Ghana

2019 ◽  
Author(s):  
Seth Lartey ◽  
ELLEN KONADU ANTWI-ADJEI ◽  
Solomon Agyapong ◽  
Abdul-Kabir Mohammed ◽  
Derrick N.O. Mensah ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Corneal Transplant ◽  
Cross Sectional ◽  
Willingness To Donate ◽  
Drivers License ◽  
Study Population ◽  
Good Potential ◽  
Potential Mode ◽  
Corneal Donation ◽  
Age Range

Abstract Background: Corneal transplantations are surgeries performed for irreparable corneal diseases and damage. However, there is a gap between the number of potential recipients and the number of donor corneas available. The main aim of the study was to determine the awareness and attitudes toward corneal donation among applicants and staff of DVLA, Kumasi-Ghana. Methods: A descriptive cross-sectional study was conducted. 100 participants were selected using convenient sampling method. A structured questionnaire was used to elicit responses from participants concerning awareness and attitudes toward corneal transplant. Results: The mean ± SD age of the participants was 32.05 ± 11.48years and age range, 18-67years. Males were 66% whilst females constituted 34%. 32.7% of the participants were aware of corneal donation. Majority of the participants were Christians (83.1%) and Singles (63%). Television was the source of information with the highest preponderance (49.4%). 67.3% were willing to donate their corneas after death. 63.9% were willing to indicate their donor statuses on drivers’ license form which had a significant association with willingness to donate cornea after death (p<0.05, ᵪ 2 = 12.187). Conclusion: There is a poor level of awareness (32.7%) of transplant and donation amongst the study population but a good level of willingness to donate organs (67%). Consent via driving license would seem to be a good potential mode of obtaining consent to supplement the harvesting of adequate tissues for transplant if adequate awareness is created.

scholarly journals Frequency of familial short stature identified in children presenting with short stature at a Tertiary Care Hospital in Multan, Pakistan.

2021 ◽  
Vol 28 (7) ◽  
pp. 993-996
Author(s):  
Waqas Imran Khan ◽  
◽  
Asia Noreen ◽  
Summera Tabasum ◽  
◽  
...  
Keyword(s):  
Short Stature ◽  
Tertiary Care ◽  
Female Gender ◽  
P Value ◽  
Care Hospital ◽  
Pediatric Endocrinology ◽  
Multicenter Studies ◽  
Study Population ◽  
Age Range ◽  
Study Setting

Objectives: The objective of my study was to determine the frequency of familial short height in children aged 3 to 14 years with short height. Study Design: Descriptive study. Setting: Department of Pediatric Endocrinology at The Children Hospital & Institute of Child health Multan (CH& ICH). Period: 1st November 2018 to 31st October 2019. Material & Methods: Eighty four patients were enrolled after taking informed consent from parents/guardians. Heights of all patients, parental heights, mid parental heights were plotted on CDC growth charts. Patients having familial short stature were noted down. Results: Out of 84 patients, 59 (70.2%) were males and 25 (29.85%) were females. Age range was 3-14 years. Mean age of the population was 8.68 ± 3.42 years and mean height and weight were 114.29 ± 24.62cm and 28.95±10.01 kg, respectively. Mean height for mother and father of the patients were 154.39 ±4.56cm and 171.10 ± 3.52cm, respectively. Out of 84 children, 21 (25%) patients had FSS. In our study population FSS was more seen in children < 8 years of age, female gender and families with income of > 20K/months with p value of 0.879, 0.129 and 0.592 respectively. Conclusion: Majority of children presenting with short stature have FSS and CDG and do not have an endocrine disorder. In our study, frequency of familial short stature in children aged 3 to 14 years was 25%. The results should be validated in multicenter studies.

scholarly journals The Prevalence of Root Fractures among Patients Visiting a Specialised Tertiary Care Dental Care Clinic

2018 ◽  
Vol 1 (12) ◽  
pp. 377-381
Author(s):  
Savita Sharma ◽  
Abhey Chowdhry
Keyword(s):  
Dental Care ◽  
Tertiary Care ◽  
T Test ◽  
Endodontic Treatment ◽  
Endodontically Treated Teeth ◽  
Care Clinic ◽  
Root Fracture ◽  
Vertical Fracture ◽  
Study Population ◽  
Root Fractures

INTRODUCTION: Following endodontic therapy, the development of root fracture(s) is considered to be a risk factor. It can be diagnosed accurately with the help of various radiographic aids.AIM: To assess the prevalence of horizontal and vertical root fractures among endodontically treated teeth among patients visiting a specialised tertiary care dental care clinic.METHODOLOGY: Patients suspected of having root fracture (due to endodontic treatment or non-endodontic treatment) were confirmed with the help of radiographic aids (IOPAR, OPG and occlusal radiographs). Root fractures due to endodontic treatment were then classified as horizontal and vertical root factures and analysed using the student’s t-test, ANOVA and odd’s ratio (OR). Data was analysed using SPSS version 21.0RESULTS: The study population comprised of 383 subjects. Males (207, 54%) formed a majority of the study population. Majority of fractures were seen in females [(162, 58.5%), endodontically treated teeth], while a slightly increased prevalence was seen among males (92, 86.8%) in non-endodontically treated teeth. A total of 277(72.3%) teeth were endodontically treated [155(55.9%) horizontal and 122(44.1%) vertical fracture], while 106(27.7%) were 155 non-endodontically treated teeth [63(59.4%) horizontal and 43(40.6%) vertical fracture]. A significance difference between horizontal and vertical root fractures [p=.005(t-test), p=.0025(ANOVA)] was seen. Odd’s ratio analysis revealed that horizontal fractures (OR=2.2) were more prone to develop as compared to vertical fractures.CONCLUSION: Owing to the fact that endodontically treated teeth are more brittle as compared to non-endodontically treated teeth, it is advised that the dental clinician should closely routinely follow- up endodontically treated teeth for signs of root fracture and confirm with a radiographical aid when such fractures are suspected.

scholarly journals Awareness and Attitudes toward Corneal Transplants among Applicants and Staff of a Driver, Vehicle and Licensing Authority (DVLA) in Ghana

2019 ◽  
Author(s):  
Seth Lartey ◽  
ELLEN KONADU ANTWI-ADJEI ◽  
Solomon Agyapong ◽  
Abdul-Kabir Mohammed ◽  
Derrick N.O. Mensah ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Corneal Transplant ◽  
Cross Sectional ◽  
Willingness To Donate ◽  
Corneal Transplants ◽  
Drivers License ◽  
Study Population ◽  
Good Potential ◽  
Potential Mode ◽  
Age Range

Abstract Introduction: Corneal transplantations are surgeries performed for irreparable corneal diseases and damage. However, there is a gap between the number of potential recipients and the number of donor corneas available. The main aim of the study was to determine the awareness and attitudes towards corneal transplants among applicants and staff of DVLA, Kumasi-Ghana. Materials and Methods: A descriptive cross-sectional study was conducted. 100 participants were selected using convenient sampling method. A structured questionnaire was used to elicit responses from participants concerning awareness and attitudes toward corneal transplant. Results: The mean ± SD age of the participants was 32.05 ± 11.48years and age range, 18-67years. Males were 66% whilst females constituted 34%. 32.7% of the participants were aware of corneal transplant. Majority of the participants were Christians (83.1%) and Singles (63%). Television was the source of information with the highest preponderance (49.4%). 67.3% were willing to donate their corneas after death. 63.9% were willing to indicate their donor statuses on drivers’ license form which had a significant association with willingness to donate cornea after death (p<0.05, ᵪ2= 12.187). Conclusion: There is a poor level of awareness (32.7%) of transplant donation amongst the study population but and a good level of willingness to donate organs (67%). Consent via driving license would seem to be a good potential mode of obtaining consent to supplement the harvesting of adequate tissues for transplant if adequate awareness is created. Keywords: Knowledge, Willingness, Unwillingness, Cornea, DVLA

scholarly journals GAMBARAN GLUKOSA DARAH DAN KOLESTEROL PADA PEDAGANG DI OBYEK WISATA SANGEH KECAMATAN ABIANSEMAL KABUPATEN BADUNG

2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Ida Arjani
Keyword(s):  
Blood Glucose ◽  
Negative Impact ◽  
Tourist Attraction ◽  
Glucose Levels ◽  
Female Sex ◽  
Cholesterol Levels ◽  
Blood Glucose Levels ◽  
Study Population ◽  
Age Range ◽  
Sufficient Concentration

Bacground The level of glucose in the blood must be kept in a sufficient concentration to provide nutrition for body organs. But on the contrary, the concentration of glucose that is too high can have a negative impact as osmotic diuresis and cellsdehydration. Therefore, blood glucose should be maintained in a constant concentration. Objective The purpose of this study is to describe the levels of blood glucose and cholesterol in traders at Sangeh tourist attraction, Abiansema, District of Badung. Methods This study is a descriptive study. Population of this research was all traders at Sangeh Tourist attraction or about 132 traders. 50 sample was selected by random sampling. Results showed blood glucose levels at any of the 50 samples, 84% normal and 16% higher. Blood glucose levels> 140 mg / dL by age group most in the age range 55 years and over is 12%, the blood glucose levels 140 mg / dL by gender be obtained at most in the female sex is as much as 10%. Test results cholesterol levels of 50 samples of 24% normal and 76% high cholesterol levels> 200 mg / dL based on age in range 55 years and over 36% whereas cholesterol levels 200 mg / dL highs also in the female sex is as much as 60%. Keywords : Blood glucose, cholesterol, traders

scholarly journals Knowledge regarding prevention of child abuse among parents at selected rural area of Western Rajasthan

2020 ◽  
Vol 8 (1) ◽  
pp. 212
Author(s):  
Nisha Yadav ◽  
Nirmala Kumari ◽  
Parmeshwari . ◽  
Pooja . ◽  
Pooja . ◽  
...  
Keyword(s):  
Domestic Violence ◽  
Child Abuse ◽  
Informed Consent ◽  
Survey Design ◽  
Sampling Technique ◽  
The People ◽  
Study Population ◽  
Level Of Knowledge ◽  
Descriptive Survey ◽  
Structured Questionnaire

Background: Child abuse is a kind of domestic violence that involves all forms of physical, emotional and sexual maltreatment and negligence of children under the age of 18 years which potentially or actually damages all aspects of their health. Child abuse is a global problem with serious lifelong consequences. In India the child abuse has not received enough attention. There have been few and irregular efforts to understand and address the problem. Aim was to assess the level of knowledge regarding prevention of child abuse among parents.Methods: Descriptive Survey design was used. The study population comprised of parents of children less than 18 years of age. A sample of 60 parents were selected by non-probability purposive sampling technique. A self-structured questionnaire was used to assess the knowledge regarding child abuse among parents. Informed consent was taken from each participant prior to data collection and descriptive and inferential statistics were used to analyse the data.Results: Majority of parents 60% had poor or fair level of knowledge, 39% had good knowledge whereas only 1.6% had excellent knowledge. There was a significant association between knowledge and age of mother at 0.02 level of significance.Conclusions: The finding of the study concluded that the knowledge regarding child abuse among parents was inadequate.  Considering this aspects further awareness drives can be conducted to make the people alert about child abuse and its prevention.

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