scholarly journals Serum vitamin A, E & C in cortical & nuclear cataract patients.

2021 ◽  
Vol 28 (08) ◽  
pp. 1137-1141
Author(s):  
Ghazala - ◽  
◽  
Jamil Ahmed Siddiqui ◽  
Syed Naqeeb Ali ◽  
Syed Liaquat Ali ◽  
...  
Keyword(s):  
Blood Level ◽  
Demographic Data ◽  
Serum Vitamin ◽  
Sampling Technique ◽  
Antioxidant Vitamins ◽  
Nuclear Cataract ◽  
Control Subjects ◽  
Significant Difference ◽  
The Status ◽  
Cataract Patients

Objective: To assess the status of antioxidant vitamins (A, E & C) in cortical and nuclear cataracts patients. Study Design: Prospective Comparative study. Setting: Al-Ibrahim Eye Hospital and Biochemistry Department of Al-Tibri Medical College, Karachi. Period: Sept 2016 to Aug 2017. Material & Methods: A non-probability random sampling technique was used on 80 pre-diagnosed cataracts (cortical and nuclear) patients, and 40 control subjects were selected for the study. The demographic data were collected, and the blood sample of control and cataract patients were analyzed for random blood sugar and antioxidant vitamins (A, E, and C) by Elisa Method. Results: The Blood level of vitamins E was low in cataract patients as compared to control subjects. Conclusions: The blood level of vitamin E is less in cortical and nuclear cataract patients as compared to control but had shown no significant difference between cortical and nuclear cataract patients.

scholarly journals Oxidative stress and antioxidant vitamins in cataract patients

2019 ◽  
Vol 7 (5) ◽  
pp. 1568
Author(s):  
Ghazala . ◽  
Syed Liaquat Ali ◽  
Jamil Ahmed Siddiqui ◽  
Aziza Khanam ◽  
Saleh Memon
Keyword(s):  
Oxidative Stress ◽  
Demographic Data ◽  
Antioxidant Vitamins ◽  
Blood Levels ◽  
Contributory Factor ◽  
Antioxidant Vitamin ◽  
Diabetic Cataract ◽  
Age Related ◽  
Significant Difference ◽  
Cataract Patients

Background: In Pakistan age related vision disturbances are mainly due to cataract. Various studies have reported relationship of ocular lesion with senile changes and diabetes mellitus resulting in reduced quality of life due to vision. Oxidative stress is an important factor in the process of cataractogenesis. The pathogenesis of the cataract may involve decreased activity of antioxidant scavenging system which includes non-enzymatic natural antioxidants as biomolecules such as carotenoids and vitamins. So, it is planned to investigate the level of serum antioxidant vitamins in diabetic cataract patients and in non-diabetic cataract patients.Methods: The study was conducted at Biochemistry department, Al-Tibri Medical College Karachi from October 2016 to October 2017. Ninety pre diagnosed cataract patients were selected from Al-Ibrahim Eye Hospital Karachi 40 normal control subjects were selected from the same population with same socioeconomic group. The demographic data was analyzed. The random blood sugar, antioxidant vitamins (C, A and E) and malondialdehyde were analyzed in the blood sample of control and cataract patients. The data was analyzed by SPSS version 20.Results: There was no significant difference in the level of vitamin C, A, E and MDA between diabetic and non-diabetic cataract patients, but the blood levels of vitamins of control are higher as compared to the cataract patients. The level of MDA is significantly high in cataract patients as compared to control. Antioxidant vitamin E was negatively correlated with serum malondialdehyde in cataract patients.Conclusions: It is concluded that in diabetic and non-diabetic cataract low level of serum antioxidant vitamins may be a contributory factor for cataractogenesis.

scholarly journals A study to assess the knowledge on weaning practice among postnatal mothers

2020 ◽  
Vol 11 (3) ◽  
pp. 3601-3605
Author(s):  
Beautily V
Keyword(s):  
Demographic Data ◽  
Sampling Technique ◽  
Demographic Variables ◽  
Family Status ◽  
Chi Square ◽  
Number Of Children ◽  
Adequate Knowledge ◽  
Significant Difference ◽  
Level Of Knowledge ◽  
Female Baby

The purpose of the study was to assess the knowledge regarding weaning among the working mothers and to find the association between the level of knowledge regarding weaning among mothers of infant with their selected demographic variables. Descriptive approach will be used to conduct the study. Non experimental descriptive design will be adopted for the study. Study was conducted in selected area at kuthambakkam. The mothers who are having infants and residing in kuthambakkam. The mother who has only one baby, whose age is less than one year, was the study samples. The sample size was 30 mothers of infant. The sampling technique adopted for the study was non probability purposive sampling. Regarding demographic data 25 (83.33%) women are between the age of 24-30 years, most of them are having 1-2 (86.66%) number of children. Family status in that 27 (90%) of the women they are in middle class family and the religious 20(66.66%) of the women they are in Hindu. Out of 30 women in that 21 (70) of the women they are having female baby. Regarding the level of knowledge 22 (73.33%) women’s are having adequate knowledge, 5(16.66%) women’s are having moderate knowledge and then 3(10%) women’s are having inadequate knowledge. The association was done by using chi-square test there is significant association between knowledge with variable education and occupation at p = (0.05) significant levels. There is no significant difference with other demographic variables.

scholarly journals The Relationship between Serum Levels of Vitamin C, Uric Acid and Antioxidant status with Coronary Artery Disease: a Case-Control Study

2020 ◽  
Author(s):  
Aida Torkzaban ◽  
Seyed Amir Mansour Alavi Naeini ◽  
Akbar Hassanzadeh ◽  
Mehrdad Namdari
Keyword(s):  
Uric Acid ◽  
Vitamin C ◽  
Antioxidant Status ◽  
Case Control Study ◽  
Demographic Data ◽  
Serum Vitamin ◽  
Serum Levels ◽  
Case Control ◽  
Significant Difference ◽  
Control Study

Abstract Background: Coronary Heart Disease (CHD) is among the main causes of death in adults. Increase of oxidative stress and defects in antioxidant defense play a major role in endothelium performance and are an effective factor in progress of atherosclerosis. The aim of this study is to measure the serum level of UA and vitamin C as well as the antioxidant status of CHD patients to evaluate their relationship and compare them with the healthy individual.Materials and methods: The present case-control study was performed on 44 cases and 44 controls. Demographic data and anthropometric indices were measured. Food frequency questionnaire (FFQ) and international physical activity questionnaire were also completed. After 12 hours of fasting, 10 ml blood was sampled from the participants. Uric acid (UA), vitamin C, TAC and MDA were also measured. The data were finally analyzed by SPSS Ver 22 software.Results: A significant difference was observed between the two groups in terms of uric acid (P<0.001) and vitamin C (P<0.03). However, mean MDA and TAC showed no significant difference between the two groups. The two groups’ difference in terms of vitamin A, E and beta carotene, zinc and selenium intake was not significant. A significant difference was however detected between the two groups in terms of vitamin C intake (P<0.047). A significant relationship was also observed between the systolic blood pressure and CHD (P<0.028).Conclusion: Our results suggest that increasing of serum uric acid and a decrease in serum vitamin C level can be considered as risk factors for CHD patients. Due to the lack of significant correlation between TAC and CHD in this study, it seems that different results will be obtained with increasing sample size.

scholarly journals Impact of tobacco use on oxidative stress in cataract

2020 ◽  
Vol 11 (3) ◽  
pp. 2942-2947
Author(s):  
Vaishali S Pawar ◽  
Ajit Sontakke
Keyword(s):  
Oxidative Stress ◽  
Risk Factors ◽  
Tobacco Use ◽  
Smokeless Tobacco ◽  
Nuclear Cataract ◽  
User Group ◽  
Tobacco User ◽  
Age Related ◽  
Significant Difference ◽  
Cataract Patients

Even today, the leading cause of visual impairment is age related cataract.  Among the risk factors for cataract, tobacco is one of the modifiable risk factors. Association between smoking and increased oxidative stress among cataract patients has been shown by some studies. But studies related to smokeless tobacco use are not done. The aim of the study was to estimate oxidative stress by markers like enzymatic antioxidant Superoxide Dismutase (SOD) and lipid peroxiation product Malondialdehyde (MDA) in tobacco user age related cataract (ARC) subjects and compare them with tobacco nonuser age related cataract (ARC) subjects. This cross sectional study was performed in 120 subjects divided into 2 groups – 60 tobacco nonuser age related cataract subjects and 60 tobacco user age related cataract subjects. 60 tobacco user cataract subjects divided into 5 groups - tobacco smokers, tobacco chewers, tobacco mishri users, dual tobacco chewers with mishri users and dual smokers with smokeless tobacco users. Oxidative stress was assessed by estimation of erythrocytic SOD and serum MDA. The study showed that in tobacco user group age of cataract patients was significantly less than tobacco nonuser cataract patients (P<0.05).  Serum MDA levels were significantly high and erythrocytic SOD levels were significantly low in tobacco user cataract patients than tobacco nonuser cataract patients (P<0.001).  Nuclear cataract was significantly more in tobacco user group (P<0.05).  On comparison of subtypes of cataract in tobacco user subgroup, no significant difference was found. These results suggested that age related Cataract occurs at an earlier age in tobacco users due to increased oxidative stress. Also nuclear cataract was significantly associated with tobacco use.

scholarly journals Prevalence of Educational Malpractice among University Students as Perceived by Lecturers of Delta State University, Abraka

2018 ◽  
Vol 7 (4) ◽  
pp. 187
Author(s):  
Anna Onoyase
Keyword(s):  
University Students ◽  
Sampling Technique ◽  
State University ◽  
Educational Malpractice ◽  
Significant Difference ◽  
High Prevalence ◽  
The Status ◽  
Research Questions ◽  
Descriptive Survey ◽  
Delta State University

The study examined the prevalence of educational malpractice among University students as perceived by lecturers of Delta State University, Abraka. Three research questions were raised to guide the study. The study is a descriptive survey research. The purposive random sampling technique was used to select a sample of 92 lecturers for the study. The instrument for this study is the questionnaire. The instrument has face and content validity through expert judgement and instrumentation. The Cronbach alpha procedure was used to assess the internal consistency of the items. The value obtained was .73. The results revealed that there is a high prevalence of educational malpractice among undergraduates of Delta State University, Abraka. The findings also revealed that there is no significant difference between lecturers in their perception of the prevalence of educational malpractice among students. Lastly, the result showed that the status of lecturers has no impact on their perception of the prevalence of educational malpractice among students. Implications for counselling practice and education were discussed.

Application of Prechop Technique in Phacoemulsification for Cataract Patients with Highly Liquefied Vitreous: A Retrospective Study

2021 ◽  
Author(s):  
Jing Zhao ◽  
Zhouyue Li ◽  
Yu Liu ◽  
Xiaotong Han ◽  
Shengsong Huang
Keyword(s):  
Retrospective Study ◽  
Intraoperative Complications ◽  
Average Energy ◽  
Good Alternative ◽  
Dissipated Energy ◽  
Control Group ◽  
Nuclear Cataract ◽  
Significant Difference ◽  
Cataract Patients ◽  
Phaco Time

Abstract Background Phacoemulsification using phaco-chop technique has many challenging features in cataract patients with highly liquefied vitreous. This study aimed to compare the intraoperative parameters and safety between prechop technique and traditional phaco-chop in phacoemulsification for these patients. Methods A total of 54 eyes of 54 patients with high myopia-related or post-vitrectomy cataract that underwent phacoemulsification combined with intraocular lens implantation were included in this retrospective study. Of them, 25 eyes that received manual prechop were included in the prechop group, and 29 eyes with best match of age, axial length and nuclear opalescence (NO) that received standardized phaco-chop were included as the control group. The intraoperative complications and surgery parameters were compared between groups. Results No surgical complications were observed in the prechop group, while 2 eyes of posterior capsular rupture and 1 eye with a broken ciliary zonule (10.3%) were found in the control group. There was no significant difference in phaco time, average energy, and cumulative dissipated energy (CDE) between groups (all P > 0.05), but for hard nuclear cataract with NO grading ≥ 5, prechop group had less phaco time (P = 0.008) and CDE (P = 0.029). The correlations between phaco time vs. NO (r = 0.762 vs. 0.581, both P < 0.005) and CDE vs. NO (r = 0.717 vs. 0.668, both P < 0.001) seemed to be weaker in the prechop group as compared to the control group. Conclusions The prechop technique which seemed to have less intraoperative complications, reduced phaco time and CDE compared to standardized phaco-chop might be a good alternative for cataract patients with highly liquefied or vitrectomized vitreous, especially those with hard nuclear cataract.

scholarly journals Vitamin D and Parathyroid Hormone Status in Female Garment Workers: A Case-Control Study in Bangladesh

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Shakil Mahmood ◽  
Matiur Rahman ◽  
Subrata Kumar Biswas ◽  
Shaikh Nazmus Saqueeb ◽  
Shiblee Zaman ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Serum Vitamin ◽  
Control Group ◽  
Case Group ◽  
Serum Vitamin D ◽  
Garment Workers ◽  
Significant Difference ◽  
The Status ◽  
The Mean

Despite the abundant sunlight, vitamin D deficiency is prevalent in South Asian countries including Bangladesh. Information on vitamin D level is insufficient in adults particularly in female garment workers in Bangladesh. This study was designed to evaluate the status of vitamin D, parathormone (PTH), calcium, and alkaline phosphatase (ALP) among the female garment workers in Bangladesh. Blood samples were collected from female garment workers (n=40, case group) and general female workers (n=40, control group) in Dhaka. Serum vitamin D, PTH, calcium, and ALP were measured by chemiluminescence microparticle immunoassay. The mean level of vitamin D was significantly (p<0.001) lower in case (14.2±2.6 ng/mL) than in the control (22.4±2.4 ng/mL) group. No significant difference was found at mean of PTH and calcium between case (33.9±17.2 pg/mL;9.1±0.6 mg/dL, resp.) and control (35.9±16.3 pg/mL;9.3±0.6 mg/dL, resp.) group. The mean ALP in case (117.2±14.4 U/L) group was significantly (p<0.001) higher than the control group (80.5±30.6 U/L). Overall, PTH level did not show significant correlation with vitamin D. However, calcium and ALP levels showed a significant positive (p<0.05) and negative (p<0.001) correlation with vitamin D, respectively. This study indicates a high prevalence of vitamin D deficiency in the female garment workers in Bangladesh.

scholarly journals Association of long term sodium valproate monotherapy and vitamin D3 levels in epileptic children

2021 ◽  
Vol 25 (1) ◽  
pp. 117-121
Author(s):  
Anum Shah ◽  
Imran Mahmood Khan ◽  
Sajid Hussain Sherazi ◽  
Taniah Ashfaq ◽  
Sajid Hussain Shah
Keyword(s):  
Vitamin D ◽  
Sodium Valproate ◽  
Vitamin D3 ◽  
Demographic Data ◽  
Serum Vitamin ◽  
Vitamin D Levels ◽  
Significant Difference ◽  
Epileptic Children ◽  
Vitamin D3 Deficiency

Objective: To determine the association of long term sodium valproate monotherapy and vitamin D3 levels in epileptic children Methods: This cross-sectional study was conducted in the Department of Pediatrics, Children Hospital, Pakistan Institute of Medical Sciences, Islamabad for six months from 15th February 2019 to 14th August 2019. A total of one hundred and thirty (n=130) children and adolescents of either gender between age 3-18 years who had a history of two seizures at least 24 hours apart in their life and were on sodium valproate monotherapy for more than one year were enrolled in this study through non-probability, consecutive sampling. Serum vitamin D3 (25-hydroxy vitamin D) levels were measured in all the patients at the time of enrolment into the study. All the demographic data and laboratory investigations were entered on the predesigned proforma and analyzed through SPSS version 17. Results: Vitamin D3 deficiency was found in 47 (36.2%) children which were significantly higher among patients with older age and longer duration of treatment (P<0.05) while gender and BMI of the patients did not show any significant difference (P>0.05). Conclusion: Significant percentage of epileptic children on sodium valproate monotherapy was found to have vitamin D3 deficiency. Therefore we recommend routine screening of vitamin D3 deficiency in all the epileptic children on long-term sodium valproate therapy followed by vitamin D supplementation in deficient patients.  

scholarly journals Helicobacter pyloriInfection and Anemia in Taiwanese Adults

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Hsiang-Yao Shih ◽  
Fu-Chen Kuo ◽  
Sophie S. W. Wang ◽  
Yi-Chang Liu ◽  
Meng-Chieh Wu ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Serum Iron ◽  
Large Scale ◽  
Binding Capacity ◽  
Statistical Significance ◽  
Demographic Data ◽  
Deficiency Anemia ◽  
Significant Difference ◽  
The Status ◽  
Iron Binding Capacity

Background. ChronicHelicobacter pyloriinfection and iron-deficiency anemia (IDA) are common in adults. Although the most common causes of IDA usually arise from the gastrointestinal tract, the association between chronicHelicobacter pyloriinfection and anemia remains unclear.Aim. To evaluate the association of chronicHelicobacter pyloriinfection and IDA.Materials and Methods. We enrolled 882 patients from January 2010 to April 2013. The status ofHelicobacter pylori(H.p) infection was confirmed and blood samples from the same participants were taken on the same day to check the level of hemoglobin, serum iron, ferritin, and total iron-binding capacity (TIBC).Results. No significant difference was noted from the demographic data. The average level of hemoglobin (Hb) was not different between negative and positive groups, pos 13.57 g/dL versus neg 13.65 g/dL (P=0.699). Although the levels of serum IDA related parameters were expected in positive group (lower serum iron and ferritin and higher TIBC) these differences did not reach statistical significance (P=0.824for iron,P=0.360for ferritin, andP=0.252for TIBC).Conclusion. ChronicHelicobacter pyloriinfection is not attributed to IDA. The levels of hemoglobin, serum iron and ferritin, and TIBC remain unaffected after chronic H.p infection. Large-scale clinical studies are needed to prove the association.

scholarly journals Professionalism among Intern Doctors of Different Medical College Hospitals in Bangladesh

2017 ◽  
Vol 7 (2) ◽  
pp. 17-22
Author(s):  
Syed Golam Samdani ◽  
Tahmina Begum
Keyword(s):  
Professional Competence ◽  
Sampling Technique ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Female Ratio ◽  
Medical College ◽  
Attitude And Practice ◽  
Significant Difference ◽  
Male Female Ratio ◽  
The Status

This descriptive cross-sectional study was conducted to explore the status of professionalism regarding knowledge, attitude and practice among intern doctors of different medical college Hospitals in Bangladesh. Study period was July 2015 June 2016.Sample size was 300 and convenient sampling technique was adopted. Study was carried out among all Bangladeshi intern doctors of 4 governments and 2 non-governments selected medical college Hospitals of Dhaka and outside Dhaka. Total 300 intern doctors responded to a self-administered questionnaire. Male female ratio was almost 1:1. Concept of professionalism and level of knowledge regarding its various aspects are not satisfactory in large extends. But attitude towards most of the major principles of professionalism are as much as positive like USA and UK physicians. However, regarding honesty with patients, one statement like physicians should disclose all significant medical errors to affected patients and/or guardians, only 36.9% agreed with this. Similarly, only 43% agreed the statement of re-certification examination to maintain professional competence. Regarding attitude and practice of major attributes & responsibilities of professionalism there is no significant difference (p>0.05) between male and female intern doctors working in different medical college hospitals; but regarding practice there is a significant difference (p<0.05) among intern doctors working in government and non-government hospitals. This study recommended that institutional agreement should be on a definition, setting expectations & curriculum framework regarding professionalism to increase scope of teaching & learning in our undergraduate & post-graduate students.Bangladesh Journal of Medical Education Vol.7(2) 2016: 17-22

Sign in / Sign up

Export Citation Format

Share Document