scholarly journals Factors Associated to Growth Disorder in Children with Thalassemia Major

2021 ◽  
Vol 9 (2) ◽  
Author(s):  
Nurbaiti Annisaa Soegiharto ◽  
Meiyanti Meiyanti
Keyword(s):  
Data Analysis ◽  
Medication Adherence ◽  
Parental Education ◽  
Iron Chelation ◽  
Thalassemia Major ◽  
Growth Disorders ◽  
Chi Square ◽  
Cross Sectional ◽  
Factors Associated ◽  
Adherence Scale

Growth disorders in short stature are often found in patients with β-thalassemia major. It is caused by several factors such as hypoxia, hemosiderosis, deficiency of nutritional intake, and micronutrient. Disorder in growth will affect the patient's quality of life. This study aims to determine the prevalence of growth disorders and analyze the factors associated with thalassemia child growth disorders. This study used an observational analytic study with a cross-sectional design on 167 patients with β-thalassemia major at the Palang Merah Indonesia Hospital, Bogor, West Java, in October–December 2018. Data was collected using a transfusion compliance questionnaire and the Morisky Medication Adherence Scale (MMAS-8), while growth was assessed using the CDC 2000 height/age curve. Data analysis used SPSS for Windows version 21.0. Of 167 subjects, 86 subjects (51.5%) were not adherent to transfusion, 97 subjects (58.1%) had low consumption of chelation iron, and 146 subjects (87.4%) had growth problems. The results of bivariate data analysis using the chi-square test for transfusion compliance and parental education on growth obtained p=0.000 and p=0.032. Likewise, for compliance with iron chelation consumption and parents' income to growth, the p value=0.000 was obtained. It was concluded that the prevalence of growth disorders was 87.4%, and there was a relationship between transfusion compliance, parental education level, parents' income, and compliance with iron chelation consumption on growth disorders in thalassemia children. FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN GANGGUAN PERTUMBUHAN PADA ANAK TALASEMIA MAYORGangguan pertumbuhan berupa perawakan pendek sering ditemukan pada penderita talasemia β mayor. Hal ini disebabkan oleh beberapa faktor seperti hipoksia, hemosiderosis, kekurangan asupan nutrisi, dan mikonutrien. Gangguan pertumbuhan akan memengaruhi kualitas hidup pasien. Penelitian ini bertujuan mengetahui prevalensi gangguan tumbuh kembang dan menganalisis faktor-faktor yang berhubungan dengan gangguan tumbuh kembang anak talasemia. Penelitian ini menggunakan jenis penelitian observasional analitik dengan desain cross-sectional pada 167 pasien talasemia β mayor di RS Palang Merah Indonesia, Bogor, Jawa Barat pada bulan Oktober–Desember 2018. Pengumpulan data dilakukan dengan menggunakan kuesioner kepatuhan transfusi dan Morisky Medication Adherence Scale (MMAS-8), sedangkan pertumbuhan dinilai menggunakan kurva tinggi/usia CDC 2000. Analisis data menggunakan SPSS for Windows versi 21.0. Dari 167 subjek, 86 subjek (51,5%) tidak patuh pada transfusi, 97 subjek (58,1%) memiliki konsumsi kelasi besi rendah, dan 146 subjek (87,4%) mengalami gangguan pertumbuhan. Hasil analisis data bivariat menggunakan uji chi-square untuk kepatuhan transfusi dan pendidikan orangtua tentang pertumbuhan diperoleh p=0,000 dan p=0,032. Begitu pula untuk kepatuhan konsumsi kelasi besi dan pendapatan orangtua terhadap pertumbuhan diperoleh p=0,000. Disimpulkan bahwa prevalensi gangguan tumbuh kembang sebesar 87,4% dan terdapat hubungan kepatuhan transfusi, tingkat pendidikan orangtua, pendapatan orangtua, dan kepatuhan konsumsi kelasi besi dengan gangguan tumbuh kembang anak talasemia.

scholarly journals Medication Adherence Status and its related Factors among Older Adults in Yazd, Iran

2020 ◽  
Author(s):  
Sara Jambarsang ◽  
Aliakbar Vaezi ◽  
Tayebeh Sanati
Keyword(s):  
Older Adults ◽  
Medication Adherence ◽  
Population Aging ◽  
Cross Sectional Study ◽  
Demographic Variables ◽  
Age Group ◽  
Chi Square ◽  
Related Factors ◽  
Cross Sectional ◽  
Adherence Scale

Introduction: One of the main problems facing different societies in the world, including Iran, is population aging and its consequences. With individuals entering old age, the possibility of being afflicted with one or more chronic diseases increases, which in turn results in more use of medications and medication adherence. This study has examined medication adherence status and its related factors among older adults in Yazd, Iran. Methods: Totally 196 individuals aged 60 years old and higher in Yazd were entered randomly in this cross-sectional study. The data were collected using Morisky Medication Adherence Scale. Chi-square and Gamma tests were used for data analysis. Results: The medication adherence was weak in 79.1%, average in 19.9%, and high in only 1% of the participants. There was not a significant relationship between demographic variables and medication adherence. Conclusion: As most of the participants were weak in medication adherence, the necessary actions for the identification of other factors that lead to the reduction of medication adherence can pave the way for providing solutions for increasing medication adherence in this age group.  

scholarly journals Kepatuhan Konsumsi Obat Kelasi Besi dan Kadar Serum Feritin Pasien Talasemia Beta-Mayor di RSUD Al-Ihsan Bandung

2020 ◽  
Vol 2 (1) ◽  
pp. 26-30
Author(s):  
Hutari Gustiana ◽  
Tito Gunantara ◽  
Hilmi Sulaiman Rathomi
Keyword(s):  
Medication Adherence ◽  
Chi Square ◽  
Cross Sectional ◽  
Morisky Medication Adherence Scale ◽  
Adherence Scale ◽  
Scale 8

Kadar serum feritin yang tinggi pada pasien talasemia menimbulkan berbagai komplikasi yang menurunkan kualitas hidup pasien. Kadar tersebut dipengaruhi berbagai hal, salah satunya kepatuhan pasien dalam mengkonsumsi obat kelasi besi. Penelitian ini bertujuan untuk mengetahui tingkat kepatuhan konsumsi obat kelasi besi dan kadar serum feritin pada penderita talasemia beta-mayor di RSUD Al-Ihsan Bandung serta hubungan antara keduanya. Penelitian ini merupakan studi cross sectional dengan melibatkan 50 pasien talasemia di RSUD Al-Ihsan Bandung yang dipilih secara consecutive. Data tingkat kepatuhan diukur dengan kuesioner Morisky Medication Adherence Scale-8 (MMAS-8) yang diisi dengan dipandu oleh peneliti, sedangkan data kadar feritin didapatkan dari rekam medis pasien. Pengambilan data dilakukan pada bulan Juli-September 2019, data dianalisis menggunakan uji Chi square dengan bantuan piranti lunak STATA versi 13. Hasil penelitian menunjukan mayoritas penderita talasemia beta-mayor di RSUD Al-Ihsan Bandung (60%, IK 45.4% - 72.9%) memiliki tingkat kepatuhan rendah dalam konsumsi obat kelasi besi dan sebagian besar memiliki kadar serum feritin >2500 ng/ml (58%, IK 43.5% - 71.2%). Terdapat hubungan bermakna secara statistik antara tingkat kepatuhan konsumsi obat kelasi besi dengan kadar serum feritin pada penderita talasemia beta-mayor di RSUD Al-Ihsan Bandung p=0.00( p<0.05).

scholarly journals Factors Related To The Needs Of Parents Having School Age Thalassemic Children

2019 ◽  
Vol 7 (2) ◽  
Author(s):  
Henny Suzana Mediani ◽  
Anita Tiara ◽  
Ai Mardhiyah
Keyword(s):  
Parental Education ◽  
Thalassemia Major ◽  
School Age Children ◽  
School Age ◽  
Chi Square ◽  
Cross Sectional ◽  
Blood Disorder ◽  
Negative Impacts ◽  
Mental And Physical Health

Thalassemia is a major genetic blood disorder that has negative impacts on thalassemic children and their family. The needs of parents while caring for thalassemia children are important matters because the failure of meeting needs of parents may affect their mental and physical health. Yet, litle is known about factors that meeting the needs of thalasemic child parents. The study aim was to identify factors that correlate with the needs of parents having a school age thalassemic child in west jave province. This research used correlational analytic with cross sectional approach. The population in this study were parents of school-age children with thalassemia major totaling 136 people using the total sampling method. Data were analyzed with bivariate using chi square and biserial points. Then a multivariate analysis used logistic regression. The results showed the age of parents related to information (p = 0.005) and professional (p = 0.004), parent gender related to information (p = 0,000), professional (p = 0.017), social (p = 0.035), financial (p = 0.023) and spiritual (p = 0.009). Parental education is related to information (p = 0,000), social (p = 0,005), emotional (p = 0,000), financial (p = 0,016) and spiritual (p = 0,001). Parent income is related to information (0,000), social (p = 0,006), emotional (p = 0,000), financial (p = 0,003) and spiritual (p = 0,004). The number of thalassemia major children is related to emotional (p = 0.015) and financial (p = 0.013). Parental needs are related to several factors. The importance of increasing the role of nurses as educators and consultants and helping parents find sources of spiritual, emotional and financial support for parents of school-age children with thalassemia. 

ADOLESCENT BEHAVIOR IN UNWANTED PREGNANCY PREVENTION

2019 ◽  
Vol 1 (1) ◽  
pp. 41-46
Author(s):  
Arip Ambulan Panjaitan
Keyword(s):  
Sexual Behavior ◽  
Reproductive Health ◽  
Risky Sexual Behavior ◽  
Parental Education ◽  
Unwanted Pregnancy ◽  
Sampling Technique ◽  
Adolescent Behavior ◽  
Cluster Sampling ◽  
Chi Square ◽  
Cross Sectional

Introduction: Adolescent are at high risk of unwanted pragnency, including abortion, STIs, HIV/AIDS. Risky sexual behavior is one of the entrance transmissions of unwanted pregnancy. Such behavior can be influenced by various factors, beyond and within the individual factors. Teens need the support and motivation in deciding not to do risky sexual behavior. The purpose of this study was to investigate the determinants of adolescent behavior in the prevention of unwanted pregnancy.Methods: This research used cross-sectional design. The populations were students of senior high school in District Sintang. The were 123 respondents chosen by cluster sampling technique for this study. All data were collected using questionnaires and then analysed using bivariate (chi square) and multivariate analysis (logistic regression).Results: The results showed that the majority of respondents did not have good knowledge about the prevention of unwanted pregnancy. Related variable is the level of parental education (p=0.001), the support of parents/guardians (p=0.009), support teachers (p=0.005), peer support (p=0.039), residency (p=0.009), a pastime activity (p=0.000), knowledge of adolescents about reproductive health (p=0.016), perception ability of adolescents (p=0.006) and attitude of adolescents (p=0.049). Adolescent self-perception abilities are variables that most influence on the behavior of adolescents in the prevention of unwanted pregnancy.Conclusions: Efforts to improve reproductive health programs should be early and adolescent have responsibilities as well as healthy behaviors.

Characteristics and risk factors associated with stroke subtypes among adult patients admitted to stroke unit of JUMC

2019 ◽  
Vol 15 ◽  
Author(s):  
Bekalu Getachew Gebreegziabher ◽  
Tesema Etefa Birhanu ◽  
Diriba Dereje Olana ◽  
Behailu Terefe Tesfaye
Keyword(s):  
Risk Factors ◽  
Stroke Unit ◽  
Medical Center ◽  
Data Entry ◽  
Public Health Problem ◽  
Cross Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Factors Associated ◽  
Stroke Subtypes

Background: Stroke is a great public health problem in Ethiopia. According to reports, in-hospital stroke mortality was estimated to be 14.7% in Ethiopia. Despite this, in this country researches done on factors associated with stroke sub-types were inadequate. Objective: To assess the Characteristics and risk factors associated with stroke sub-types among patients admitted to JUMC. Methods and materials: A retrospective cross sectional study was conducted from May 2017 to May 2018 in stroke unit of Jimma University Medical Center. A total of 106 medical charts of patients diagnosed with stroke were reviewed. Checklist comprising of relevant variables was used to collect data. SPSS version 21 was employed for data entry and analysis. Chi-square test was used to point-out association and difference among stroke sub-types. The data was presented using text, tables and figures. Result: From a total of 106 patients, 67(63.2%) were men. The mean ± SD of age was 52.67±12.46 years, and no significant association was found. Of all the patients, 59(55.6%) had ischemic strokes and 47(44.4%) had hemorrhagic strokes. The most common risk factor in the patients was alcohol use with a prevalence of 69.9%. Of all the risk factors, only sex, cigarettes smoking and dyslipidemia were significantly associated to sub-types of stroke. Conclusion: Ischemic stroke was the most common subtype of stroke. Sex of patient, cigarette smoking and dyslipidemia are significantly associated with the two stroke subtypes.

Relationship of Workload and Double Role With Work Fatigue on Batik Craftsmen

2019 ◽  
Vol 4 (2) ◽  
pp. 293
Author(s):  
Herdianti Herdianti ◽  
Tatik Maryana
Keyword(s):  
Data Analysis ◽  
Quantitative Research ◽  
Sampling Technique ◽  
Work Load ◽  
Dual Role ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test ◽  
Almost All

<p><em><em>Background: In Batik Mawar, almost all work is done manually using the hands and upper arms on a continuous basis combined with the rigor of work and the use of traditional tools. The work has a heavy workload because all the work process is done by the same craftsman causing fatigue besides that the worker also have double role. The purpose of this study is to determine the relationship between workload and dual role with feelings of fatigue on craftsmen batik roses.Method: This research is Quantitative research with Cross Sectional research design. The population in this study are all artisans in Batik Mawar. Sampling in this study using total sampling technique with the number of research samples as many as 40 respondents. Data analysis used by Univariat and Bivariat.Result: Result of data analysis using Chi-Square test for work load got value p-Value = 0,001. The result of data analysis using Chi-square test for double role got p-value = 0,031. Thus it is concluded that there is a meaningful relationship between workload and dual role with feeling tired. We recommend that craftsmen wash clothes 2 times a day, cook ready meals, other than together in completing the work at home</em></em></p><p><em><br /></em></p><p><em>Di Batik Mawar, hampir semua pekerjaan dikerjakan secara manual menggunakan tangan dan lengan atas secara berkesinambungan yang dikombinasi dengan ketelitian kerja dan penggunaan alat-alat tradisional. Pekerjaan mempunyai beban kerja yang berat dikarenakan semua proses kerja dilakukan oleh pengrajin yang sama sehingga menimbulkan kelelahan</em><em> disamping itu pekerjanya juga memiliki peran ganda</em><em>.</em><em> Tujuan penelitian ini adalah untuk mengetahui hubungan beban kerja dan peran ganda dengan perasaan lelah pada pengrajin batik mawar.Metode: </em><em>Penelitian ini merupakan penelitian Kuantitatif dengan desain penelitian Cross Sectional. Populasi dalam penelitian ini adalah semua pengrajin di Batik Mawar. Pengambilan sampel pada penelitian ini menggunakan teknik total sampling dengan jumlah sampel penelitian sebanyak 40 responden. Analisis data yang digunakan Univariat dan Bivariat.</em><em>Hasil: </em><em>Hasil analisis data yang menggunakan uji Chi-Square untuk beban kerja didapatkan nilai p-Value = 0,001. Hasil analisis data yang menggunakan uji Chi-square untuk peran ganda didapatkan nilai p-value= 0,031. Dengan demikian  disimpulkan bahwa ada hubungan yang bermakna antara beban kerja dan peran ganda dengan perasaan lelah.Sebaiknya pengrajin mencuci pakaian 2 kali sehari, memasak makanan siap saji, selain itu dengan cara bersama-sama dalam menyelesaikan pekerjaan dirumah.</em><em></em></p><strong><em></em></strong>

scholarly journals Prevalence of Insomnia and Factors Associated with it Among the Elderly People of Sarangdanda VDC in Panchthar District

1970 ◽  
Vol 4 ◽  
pp. 129-142 ◽  
Author(s):  
Raj Kumar Subedi
Keyword(s):  
Elderly People ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Interview Schedule ◽  
Chi Square ◽  
Cross Sectional ◽  
Factors Associated ◽  
Keywords Alcohol ◽  
Chi Square Test ◽  
Restorative Sleep

Insomnia is one of the major and unsolved problems in older people. Most of the sleep studies report that the different forms of insomnia like Difficulty Initiating Sleep (DIS), Difficulty Maintaining Sleep (DMS) and Non-Restorative Sleep (NRS) are common among the elderly that are associated to many factors. The objective of the study was to measure the prevalence of insomnia and the factors associated to it among the elderly people. A cross-sectional study was conducted among 142 elderly people of and above 60 years of age in Sarangdanda VDC of Panchthar District of Eastern Nepal. The presence or absence of insomnia and the associated factors were assessed on them by the help of interview schedule. The results were analyzed using chi-square test in SPSS (version 11.5). DMS was the most common reported form of insomnia among the elderly followed by DIS and NRS. Association between insomnia and each of factors like use of tobacco before sleeping hours, eating too close to bedtime, use of tea/coffee before sleeping hours and use of alcohol before sleeping hours were statistically significant at 95% level of confidence. Insomnia affects a large proportion of elderly and is triggered by many factors like use of tobacco before sleeping hours, use of tea/coffee before sleeping hours, eating too close to bedtime and use of alcohol before sleeping hours. Keywords: Alcohol; tea/coffee; difficulty initiating sleep (DIS); difficulty maintaining sleep (DMS); non-restorative sleep (NRS); tobacco DOI: 10.3126/dsaj.v4i0.4517 Dhaulagiri Journal of Sociology and Anthropology Vol.4 2010 pp.129-142

scholarly journals Exploration of COVID-19-Based Changes to Caregiver Burden and Caregiving Intensity among Informal Caregivers

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 945-945
Author(s):  
Steven Cohen ◽  
Zachary Kunicki ◽  
Megan Drohan ◽  
Mary Greaney
Keyword(s):  
Caregiver Burden ◽  
Informal Caregivers ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Multinomial Regression ◽  
Chi Square ◽  
Cross Sectional ◽  
Unpaid Care ◽  
Factors Associated ◽  
Amazon's Mechanical Turk

Abstract Individuals providing unpaid care of assistance to family members and friends (e.g. informal caregivers), may have been uniquely impacted by the COVID-19 pandemic. Research is needed to examine the pandemic’s effect on informal caregivers’ caregiving intensity and burden. Therefore, this cross-sectional study was conducted to explore self-reported changes in caregiver intensity (CI) and caregiver burden (CB) due to the pandemic to identify factors associated with changes in responsibilities and burdens. In June 2020, informal caregivers providing care to someone aged 50+ (n=835) reported their current and pre-pandemic caregiving intensity and burden. Data were collected via Amazon’s Mechanical Turk. Chi-square tests were used to examine bivariate associations between pandemic time (pre vs. post) differences in CI and CB. Multinomial regression was used to assess multivariate predictors of changes to CI and CB due to COVID-19. Results showed a significant U-shaped association between initial CB and CB change due to COVID-19. Higher levels of initial CB were associated with both a significant decrease in CB during COVID-19 (OR 1.33, 95%CI 1.06-1.67), and a significant increase in CB during COVID-19 (OR 1.22, 95%CI 1.05-1.43). There were no significant associations between initial CB and changes in CI due to COVID-19, although older caregivers were more likely to experience a decrease in CB due to caregiving (OR 1.02, 95%CI 1.00-1.05). These mixed results suggest that caregivers with high initial CB experienced the most extreme changes to CB due to COVID-19. Future planned analyses will focus on understanding the potential drivers behind these unexpected results.

scholarly journals MRI evaluation of hepatic and cardiac iron burden in pediatric thalassemia major patients: spectrum of findings by T2*

2019 ◽  
Vol 50 (1) ◽  
Author(s):  
Samar M. Shehata ◽  
Mohamed I. Amin ◽  
El Sayed H. Zidan
Keyword(s):  
Chelation Therapy ◽  
Statistical Significance ◽  
Iron Chelation ◽  
Good Method ◽  
Thalassemia Major ◽  
Local Magnetic Field ◽  
Cardiac Complications ◽  
Liver Iron ◽  
Cross Sectional ◽  
Signal Decay

Abstract Background Iron deposition distorts the local magnetic field exerting T2* signal decay. Biopsy, serum ferritin, echocardiography are not reliable to adjust iron chelation therapy. Quantified MRI signal decay can replace biopsy to diagnose iron burden, guide treatment, and follow up. The objective of this study is to evaluate the role of T2* in quantification of the liver and heart iron burden in thalassemia major patients. This cross-sectional study included 44 thalassemia patients who were referred to MRI unit, underwent T2* MRI. Results Twenty-one male (47.7%) and 23 female (52.3%) were included (age range 6–15 years, mean age 10.9 ± 2.9 years). Patients with excess hepatic iron show the following: 11/40 (27.5%) mild, (13/40) 32.5% moderate, and (14/40) 35% severe liver iron overload. High statistical significance regarding association between LIC and liver T2* (p = 0.000) encountered. Cardiac T2* values showed no relationship with age (p = 0.6). Conclusion T2* is a good method to quantify, monitor hepatic and myocardial iron burden, guiding chelation therapy and prevent iron-induced cardiac complications.

Abstract P347: Sex Differences in Barriers to Antihypertensive Medication Adherence: Findings from the Cohort Study of Medication Adherence among Older Adults (CoSMO)

Circulation ◽  
2013 ◽  
Vol 127 (suppl_12) ◽  
Author(s):  
Elizabeth W Holt ◽  
Cara Joyce ◽  
Adriana Dornelles ◽  
Donald E Morisky ◽  
Larry S Webber ◽  
...  
Keyword(s):  
Older Adults ◽  
Cohort Study ◽  
Medication Adherence ◽  
Antihypertensive Medication ◽  
Administrative Databases ◽  
Medication Cost ◽  
Lifestyle Modifications ◽  
Cross Sectional ◽  
Men And Women ◽  
Factors Associated

Objectives: We assessed whether socio-demographic, clinical, health care system, psychosocial, and behavioral factors are differentially associated with low antihypertensive medication adherence scores among older men and women. Methods: We conducted a cross-sectional analysis using baseline data from the Cohort Study of Medication Adherence in Older Adults (CoSMO, n=2,194). Low antihypertensive medication adherence was defined as a score <6 on the 8-item Morisky Medication Adherence Scale. Risk factors for low adherence were collected using telephone surveys and administrative databases. Results: The prevalence of low medication adherence scores did not differ by sex [15.0% (193 of 1,283) in women and 13.1% (119 of 911) in men p=0.208]. In sex-specific multivariable models, having issues with medication cost and practicing fewer lifestyle modifications for blood pressure control were associated with low adherence scores among both men and women. Factors associated with low adherence scores in men but not women included reduced sexual functioning (OR = 2.03; 95% CI: 1.31, 3.16 for men and OR = 1.28; 95% CI: 0.90, 1.82 for women), and BMI ≥25 (OR = 3.23; 95% CI: 1.59, 6.59 for men and 1.23; 95% CI: 0.82, 1.85 for women). Factors associated with low adherence scores in women but not men included dissatisfaction with communication with their healthcare provider (OR = 1.75; 95% CI: 1.16, 2.65 for women and OR =1.16 95% CI: 0.57, 2.34 for men) and depressive symptoms (OR = 2.29; 95% CI: 1.55, 3.38 for women and OR = 0.93; 95% CI: 0.48, 1.80 for men). Conclusion: Factors associated with low antihypertensive medication adherence scores differed by sex. Interventions designed to improve adherence in older adults should be tailored to account for the sex of the target population.

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