scholarly journals The Effect of Coffee on The Quantity of Spermatozoa of Diabetic Wistar Rats Inducted By Aloxan

2021 ◽  
Vol 4 (2) ◽  
pp. 11
Author(s):  
Ahmad Alrizaldi ◽  
Riandini Aisyah ◽  
Safari Wahyu Jatmiko
Keyword(s):  
Normal Control ◽  
Negative Control ◽  
Diabetic Rats ◽  
Control Group ◽  
Test Results ◽  
Control Group Design ◽  
White Rats ◽  
A Value ◽  
Wistar Strain ◽  
Post Test

Hyperglycemia in people with diabetes mellitus causes oxidative stress which can interfere with the provision of nutrients through blood vessels to the tissues that form spermatozoa so that it interferes with the process of spermatogenesis in the testicular organs. Coffee contains caffeine and chlorogenic acid which functions as an antioxidant to improve spermatogenesis abnormalities which causes decreased number of normal spermatozoa. The purpose of this study was to determine the ability of coffee in improving the number of spermatozoa of alloxan induced wistar white rats.. Methods this study uses Post-test only laboratory experimental research with control group design. Submitting 30 rats divided into 5 groups: normal control (given aquades), negative control (induced alloxan + aquades), setting 1 (induced alloxan + coffee 0.054 gram / 200 gramBB), aid 2 (alloxan induced + coffee 0.108 gram / 200 gramBB ) and treatment 3 (alloxan + coffee induced 0.162 gram / 200 gramBB). Provision of coffee carried out for 14 days, rats terminated on the 15th day. Testicles are taken then observed and counted spermatozoa. One-way ANOVA test results show the value of p = 0.000. In the LSD test between the normal control group (aquades) and negative control (diabetic rats without treatment) had a value of p = 0.042, whereas in the treatment group 1.2.3 with a negative control had a value of p = 0.000. Provision of coffee can increase the number of spermatozoa white wistar strain alloxan induced.

scholarly journals UJI EFEKTIFITAS FORMULA SPRAY DARI MINYAK ATSIRI HERBA KEMANGI (Ocimum Sanctum L ) SEBAGAI REPELLENT NYAMUK Aedes aegypti

2017 ◽  
Vol 2 (2) ◽  
pp. 189
Author(s):  
Resmi Aini ◽  
Rina Widiastuti ◽  
Nuha Afra Nadhifa
Keyword(s):  
Essential Oil ◽  
Aedes Aegypti ◽  
Essential Oils ◽  
Negative Control ◽  
Repellent Activity ◽  
Ocimum Sanctum ◽  
Control Group ◽  
Control Group Design ◽  
A Value ◽  
Post Test

Dengue fever is transmitted by the bite of Aedes aegypti mosquitoes infected with denguevirus. Preparations antinyamuk much use of harmful chemicals such as DEET (diethylmetatoluamide) and permethrin that can lead to pollution of the environment, leavingno residue and cause resistance to the drug. To determine the activity of essential oils from herbs basil (Ocimum Sanctum L) in the preparation of spray as a mosquito repellent and determine the effective concentrationof the spray.This type of research is True experiment with design Post Test Only Control Group Design. Repellent activity was observed by means of spray is sprayed on the back of the hand probandus, then tested on female mosquitoes with the introduction into the cage containing20 mosquitoes each treatment. Spray essential oils showed repellent activity of Aedes aegypti with a value of correlation r = 0.964 higher concentration of essential oils the fewer mosquitoes that land. Spray herbal essential oil of basil (Ocimum basilicum L) has a repellent activitycompared to the negative control. The effectiveness of the herb basil essential oil sprayobtainedat 74.131 ppm lC50 and lC90 of  775.711 ppm

EFEK HEPATOPROTEKTOR EKSTRSAK JINTAN HITAM (Nigella sativa) TERHADAP KERUSAKAN HEPAR TIKUS PUTIH (Rattus norvegicus) JANTAN GALUR Sparague Dawley YANG DIINDUKSI ETANOL

2018 ◽  
Vol 6 (1) ◽  
pp. 36-44
Author(s):  
Rizky Rafiqoh Afdin ◽  
Fairuz Quzwain
Keyword(s):  
Normal Control ◽  
Rattus Norvegicus ◽  
Nigella Sativa ◽  
Control Group ◽  
Sprague Dawley ◽  
Control Group Design ◽  
Black Cumin ◽  
Group Design ◽  
White Rats ◽  
Post Test

ABSTRACT Background: Among the various medicinal plants, black cumin (Nigella sativa) appears as an herb with a historical and religious background due to a lot of research. One of the most important effects on Nigella sativa is the hepatoprotective that has been shed in various studies. Thymoquinone which is the content of Nigella sativa has the ability to inhibit lipid peroxidation. Thymoquinone can reduce oxidative stress and increase antioxidants in the body. The objectives of this study were to overcome the effects hepatoprotector of black cumin extract (Nigella sativa) on the damage of hepatic of male white rat (Rattus norvegicus) sparague dawley strain induced by ethanol. Methodology: It is a kind of experimental laboratory research used that uses random controlled design method with the pattern of post test-only control group design. The subject of this research is 25 adult male white rats (Rattus norvegicus) Sparague Dawley strain aged 3-4 months, weight 150-300 grams, that are divided in to five groups. Group one (normal control) is given aquades dose 0,01 ml/grBB/day, group two (pathologic control) is given ethanol with dose o,o1 ml/grBB/day, group three is given 25% concentration of black cumin extract and 50% ethanol, group four is given 37,5% concentration of black cumin extract and 50% ethanol, and group five is given 50% concentration of black cumin extract and 50% ethanol. After 14th days, the treatment was stopped and the rats got dislocation cervical, and then laparotomy for made histopathology preparation. After getting observed, the data that is gotten is analyzed with Kruskal-Wallis test and then Mann-Whitney test. Result: The result of Kruskal-Wallis test showed that there was an effect of black cumin extract (Nigella sativa) on the damage of hepatic of male white rat (Rattus norvegicus) sparague dawley strain induced by ethanol with p = 0,001 (p <0,05) . Mann Whitney test show there is a means difference between group I (normal control) with group II (pathologic control), group III (dose I), group IV (dose II) and group V (dose III). Conclusion: There is a hepatoprotector effect of black cumin (Nigella sativa) extract to liver’s damage of white rats (Rattus norvegicus) sparague dawley strain induced by ethanol. Key words: Black cumin extract, ethanol, fatty degeneration of liver rats.   ABSTRAK Latar Belakang: Di antara berbagai tanaman obat, jintan hitam (Nigella sativa) muncul sebagai ramuan dengan latar belakang sejarah dan agama karena banyak penelitian mengungkapkan potensi farmakologis dari tanaman tesebut. Salah satu efek yang paling penting pada Nigella sativa adalah hepatoprotektif yang ditelah dijelaskan dalam berbagai penelitian. Thymoquinone yang merupakan kandungan jintan hitam memiliki kemampuan untuk menghambat peroksidasi lipid. Thymoquinone dapat mengurangi stress oksidatif dan meningkatkan pertahanan antioksidan dalam tubuh.  Tujuan penelitian ini untuk meneliti efek hepatoprotektor jintan hitam (Nigella sativa) terhadap kerusakan hepar tikus putih (Rattus norvegicus) jantan galur Sprague Dawley yang diinduksi etanol. Metode: Jenis penelitian ini adalah eksperimental laboratorik menggunakan metode rancangan acak terkontrol dengan pola post test-only control group design. Subjek penelitian adalah 25 ekor tikus putih (Rattus norvegicus) jantan galur sparague dawley berumur 3-4 bulan, berat badan 150-300 gram, yang dibagi menjadi 5 kelompok. Kelompok I (kontrol normal) diberi aquades dosis 0,01 ml/grBB/hari, kelompok II (kontrol patologis) diberi etanol 50% dosis 0,01 ml/grBB/hari, kelompok III diberi ekstrak jintan hitam konsentrasi 25% dan etanol 50%, kelompok IV diberi ekstrak jintan hitam konsentrasi 37,5% dan etanol 50%, serta kelompok V diberi ekstrak jintan hitam konsentrasi 50% dan etanol 50%. Setelah hari ke-14, perlakuan dihentikan, dilakukan dislokasi pada leher tikus kemudian dilakukan laparotomi untuk pengambilan hepar tikus untuk dibuat preparat histopatologis. Setelah diamati, data dianalisis dengan uji Kruskal-Wallis dan dilanjutkan dengan uji Mann Whitney. Hasil: Hasil uji Kruskal-Wallis menunjukkan terdapat pengaruh ekstrak jintan hitam (Nigella sativa) terhadap kerusakan hepar tikus putih (Rattus norvegicus) jantan galur sparague dawley yang diinduksi etanol, dengan nilai p = 0,001 (p<0,05). Uji Mann Whitney menunjukkan perbandingan yang bermakna didapatkan pada kelompok I (kontrol normal) dengan kelompok II (kontrol patologis), kelompok III (dosis I), kelompok IV (dosis II) dan kelompok V (dosis III). Kesimpulan: Terdapat efek hepatoprotektor ekstrak jintan hitam (Nigella sativa) terhadap kerusakan hepar tikus putih (Rattus norvegicus) jantan galur Sprague Dawley yang diinduksi etanol.   Kata kunci: ekstrak jintan hitam, etanol, degenerasi lemak hepar tikus.

scholarly journals The Effect of Medroxy Progesterone Acetate Hormone Administration to Endometrial Thickness of the Female Rattus norvegicus Wistar strain

2020 ◽  
Vol 4 (2) ◽  
pp. 94
Author(s):  
Devi Yulita
Keyword(s):  
Rattus Norvegicus ◽  
Endometrial Thickness ◽  
Female Rats ◽  
Control Group ◽  
Gonadotropin Secretion ◽  
Control Group Design ◽  
White Rats ◽  
Wistar Strain ◽  
Post Test

Many alternative contraceptives can be used as needed. The most effective type of contraception is injection contraception because it is relatively safe, effective, simple and inexpensive. Contraceptive users must be selective in choosing contraception because there is no method of contraception that is safe and effective for all acceptors. The side effects of Medroxy Progesterone Acetat injection include bleeding disorders such as amenorrhoea, weight gain, high blood pressure, acne, spotting. Medroxy Progesterone Acetat is a progestin contraceptive regimen that is often used and works long-term. The mechanism of action of Medroxy Progesterone Acetate injection is to inhibit gonadotropin secretion so that it will prevent the maturation of primary follicles in the ovary and also prevent ovulation and cause endometrial depletion.The research design is the post test only control group design. The population in this research  are the white rats species Rattus norvegicus Wistar strain. The samples are taken randomly from all populations that met the following sample criteria: Female rats, Aged 12-14 weeks, having a body weight of 150 - 200 grams.The results showed that Medroxy Progesterone Acetate hormone affects the thickness of the endometrium, and there is a difference in the histological picture of endometrial thickness due to the administration of the Medroxy Progesterone Acetate hormone and without the administration of the Medroxy Progesterone Acetate hormone

scholarly journals Potential of Cocoa Ethanol Extract Toward Nematocyst Tubul Firing Inhibition of Physalia Utriculus Toxin In Vitro

2019 ◽  
Vol 5 (2) ◽  
pp. 30
Author(s):  
Sarwendah Siswi Winasis ◽  
Al Munawir ◽  
Adelia Handoko
Keyword(s):  
Normal Control ◽  
Ethanol Extract ◽  
Negative Control Group ◽  
Positive Control ◽  
Negative Control ◽  
Control Group ◽  
Control Group Design ◽  
Average Percentage ◽  
Post Test

There was estimated 150 million envenomation cases due to jellyfish stings occur globally every year. 100 from 10,000 jellyfish species in the world known to be dangerous, one them is Physalia utriculus. The aim of this study was to determine the potential of cocoa (Theobroma cacao L.) ethanol extract toward nematocyst tubul firing inhibition of jellyfish (Physalia utriculus) toxin in vitro. The method was true experimental design with post test only control group design. The study divided into 8 groups: 1 normal control, 1 positive control, 1 negative control, and 5 treatments grups by giving cocoa ethanol extract with concentration 20%, 2%, 0.2%, 0.02%, 0.002%. The observation was made by calculating the percentage number of firing nematocysts. The result showed average percentage of firing nematocyst in the normal control group was 42.50 ± 3.18, positive control group was 37.97 ± 5.57, negative control group was 52.44 ± 2.98, and treatment group which given with cocoa ethanol extract 20%, 2%, 0.2%, 0.02%, 0.002% were 48.24 ± 5.37; 40.62 ± 7.10; 29.45 ± 5.39; 37.60 ± 9.78; 41.11 ± 3.92, respectively. The One Way Annova statistical results test show significance value 0.001 (p≤0.05). The conclusion of this study was the cocoa ethanol extract with concentration 0.2% has most potential to inhibit the jellyfish (P. utriculus) nematocyst tubule firing in vitro. Keywords: Physalia utriculus, cocoa, toxin, jellyfish

scholarly journals The effect of e-cigarette and a conventional cigarette to the alveolus on Wistar male rats

2019 ◽  
Vol 8 (4) ◽  
pp. 251
Author(s):  
Budian Nurpangestu ◽  
Yusrotun Kharimah ◽  
Fita Linggasati ◽  
Moch Bahrudin
Keyword(s):  
Negative Control Group ◽  
Negative Control ◽  
Male Rats ◽  
Cigarette Smoke Exposure ◽  
Control Group ◽  
Control Group Design ◽  
Group Design ◽  
Wistar Strain ◽  
Post Test ◽  
Wistar Male Rats

Smoking can cause a variety of diseases one of them on pulmonary organs, e-cigarettes are also considered to be safer than conventional cigarettes and the number of smokers in Indonesia is increasing every year. The purpose of this study to determine differences in pulmonary alveolar damage in male rats (Rattus norvegicus Wistar strain) on electric cigarette smoke exposure and conventional cigarettes. This research is true experimental with post-test only control group design. Male rats were used as many as 25 rats were divided into 5 groups, namely the group P0 as a negative control group; P1 group was exposed to clove cigarettes; P2 group is exposed to a filter cigarette; P3 group was exposed to e-cigarette 0mg; P4 group exposed the e-cigarette 3mg. Samples were treated for 30 days. Data were analyzed using Kruskal Wallis with p &lt;0.05. The results showed that there were significant differences in alveolar damage in the fifth group (p = 0.003). With Mann Whitney shows that groups P1, P2, P3, and P4 there are no significant differences. The conclusion of this study is there is no difference in alveolar damage on Wistar male rats by e-cigarettes and conventional cigarettes exposure.

scholarly journals Glutamine Supplementation Effects on Reducing Inflammation in The Ileum of Acute and Chronic Diarrhea Rats Induced by Enteropathogenic Escherichia coli

2020 ◽  
Vol 12 (3) ◽  
pp. 275-82
Author(s):  
Deddy Satriya Putra ◽  
Fadil Oenzil ◽  
Eryati Darwin ◽  
Hafni Bachtiar ◽  
Tofrizal Tofrizal
Keyword(s):  
Escherichia Coli ◽  
Chronic Diarrhea ◽  
Negative Control Group ◽  
Negative Control ◽  
Glutamine Supplementation ◽  
Control Group ◽  
Enteropathogenic Escherichia Coli ◽  
Control Group Design ◽  
Wistar Strain ◽  
Post Test

BACKGROUND: Glutamine, a non-essential amino acid, is the main fuel in the gastrointestinal mucosa. It is thought to protect the intestinal mucosa against local or systemic injury from diarrhea. This study aimed to determine the relationship between glutamine supplementation and ileum histopathology in acute and chronic diarrhea rats induced by enteropathogenic Escherichia coli (EPEC).METHODS: A randomized post-test only control group design was conducted. Thirty Rattus norvegicus Wistar strain were divided into 5 groups: one negative control group, two acute, and two chronic diarrhea groups. All four diarrhea groups were induced by EPEC at a dose of 108 CFU/mL. One acute and one chronic groups were supplemented with glutamine at a dose of 810 mg/200 g body weight for 14 days. While the other two diarrhea groups were not treated. The intestinal histopathology of each group was assessed and the level of inflammation was classified.RESULTS: Significant differences in inflammation levels were found among the groups (p<0.05). The highest inflammation level was observed in the acute diarrhea group without glutamine supplementation. Inflammation levels of both acute and chronic diarrhea with glutamine supplementation groups were significantly lower than the inflammation levels of acute and chronic diarrhea without glutamine supplementation groups.CONCLUSION: Supplementation of glutamine reduces the level of inflammation and leads to the histopathological improvement of the rat’s ileum.KEYWORDS: enteropathogenic Escherichia coli, glutamine, gastrointestinal tract, histopathology, ileum

scholarly journals Pengaruh Metode Pembelajaran Mind Mapping terhadap Hasil Belajar pada Pokok Bahasan Hukum-Hukum Dasar Kimia Siswa Kelas X Semester Ganjil di SMA Negeri 2 Langowan

2019 ◽  
Vol 1 (2) ◽  
pp. 107
Author(s):  
Frindly Makarawung ◽  
I Dewe Ketut Anom ◽  
John Lombok
Keyword(s):  
Student Learning ◽  
Learning Outcomes ◽  
Student Learning Outcomes ◽  
Control Group ◽  
Test Results ◽  
Mind Mapping ◽  
Learning Methods ◽  
Control Group Design ◽  
Average Value ◽  
Post Test

This research aims to determine the effect of mind mapping learning methods on the basic laws of chemistry toward learning outcomes of students of class X MIPA in SMA Negeri 2 Langowan. The sample used in this study were all students of class X MIPA of SMA Negeri 2 Langowan. This research uses an experimental method, with the research method used is Quasi Experiment  with Nonequivalent Control Group Design design. The research data were obtained from post-test results. Obtained the average value of student learning outcomes Experiment class is 85. The results showed the value of tcount = 15.7> ttable = 2.21, so H0 was rejected and H1 was accepted. Based on the results of the research it can be concluded that there is an influence on student learning outcomes on the basic laws of chemistry using mind mapping learning methods.

scholarly journals PENGARUH PELATIHAN THREE CORNER DRILL TERHADAP PENINGKATAN KELINCAHAN DAN POWER

2018 ◽  
Vol 6 (3) ◽  
Author(s):  
I Gede Agunk Teddy Pratama ◽  
Made Budiawan ◽  
I Nyoman Sudarmada
Keyword(s):  
Treatment Group ◽  
Muscle Power ◽  
T Test ◽  
Training Effect ◽  
Control Group ◽  
Test Results ◽  
Control Group Design ◽  
Group Design ◽  
Post Test ◽  
Quasi Experimental

Penelitian ini bertujuan untuk mengetahui pengaruh pelatihan three corner drill terhadap kelincahan dan power otot tungkai. Jenis penelitian adalah quasi experimental dengan rancangan the non-randomized pretest-posttest control group design. Subjek penelitian yang digunakan siswa putra peserta ektrakurikuler sepak bola SMPN 2 Pekutatan. Data post-test kelincahan dan power otot tungkai pada kelompok perlakuan dan kelompok kontrol dianalisis dengan uji-t independent pada taraf signifikansi (α) 0,05 dengan bantuan program SPSS 16.0. Berdasarkan hasil uji-t independent didapatkan hasil : (1) untuk variabel kelincahan, hasil perbandingan kelompok perlakuan dan kontrol didapatkan nilai thitung = -2,948 , dengan nilai signifikansi 0,009, (2) untuk variabel power, hasil perbandingan kelompok perlakuan dan kontrol didapatkan nilai thitung = 3,176, dengan nilai signifikansi 0,005. Nilai signifikansi hitung lebih kecil dari nilai α (Sig < 0,05), dengan demikian hipotesis penelitian “pelatihan three corner drill berpengaruh terhadap peningkatan kelincahan dan power otot tungkai pada siswa putra peserta ektrakurikuler sepak bola SMPN 2 Pekutatan” diterima. Dari hasil analisis data dan pembahasan disimpulkan bahwa : (1) Pelatihan three corner drill berpengaruh terhadap peningkatan kelincahan pada siswa putra peserta ektrakurikuler sepak bola SMP Negeri 2 Pekutatan (2) Pelatihan three corner drill berpengaruh terhadap peningkatan power otot tungkai pada siswa putra peserta ektrakurikuler sepak bola SMP Negeri 2 Pekutatan. Kata Kunci : kelincahan, daya ledak, three corner drill The purpose of this research was to find out the effect of three corner drill training toward the increased agility and power muscle of legs. The type of research was a quasi-experimental and the design of research was the non-randomized pretest-posttest control group design. The subjects were man’s student football extracurricular participants of SMPN 2 Pekutatan. Agility and muscle power of legs posttest to the treatment group and the control group were analyzed by independent t-test at significance 0,05 with SPSS 16.0. Based on independent t-test results were showed : (1) to the agility variable, the comparison of the treatment and the control group values obtained t = -2,948, with a significance value of 0,009, (2) to muscle power of legs variable, the comparison of the treatment and the control group values obtained t = 3,176, with a significance value of 0,005. Calculated significance value smaller than the value of 0,05 (Sig < 0.05), thus the research hypothesis "three corner drill training affect the increased agility and muscle power of legs in football extracurricular participants of SMPN 2 Pekutatan " was received. From the analyzed and discussion were concluded that : (1) three corner drill training effect the increased agility in football extracurricular participants of SMPN 2 Pekutatan, (2) three corner drill training effect the increased muscle power of legs in football extracurricular participants of SMPN 2 Pekutatan. keyword : Agility, power, three corner drill

scholarly journals PENGENDALIAN NYAMUK AEDES SPP MENGGUNAKAN PERANGKAP ALAMIAH

2018 ◽  
Vol 7 (1) ◽  
pp. 95-99
Author(s):  
Deri Kermelita
Keyword(s):  
Control Group ◽  
Sugar Solution ◽  
Test Results ◽  
Control Group Design ◽  
Mosquito Trap ◽  
Post Test ◽  
Observation Cage ◽  
Palm Sugar ◽  
Primary Vector ◽  
One Way Anova

Aedes spp mosquito is the primary vector  or the main transmitter of dengue fever. it’s existence cause public health disturbing. Many research are being done to find ways of controlling mosquitoes, one of them by using a mosquito trap attractants. The purpose of this study was to determine the effectiveness of the addition of attractants to modified mosquito trap to the Aedes aegypti mosquitoes control. The study design using analytical methods with a "post-test only control group design". The number of mosquitoes that are used at each observation cage was 30, with 9 times  repetition.  One way ANOVA used to analized the data then followed by LSD test. Results modifications mosquito trap attractants addition of palm sugar solution mixed with yeast bread is more effective (ρ = 0.000) of the yeast mixed tape.

scholarly journals Jumlah Sel Neuron Cerebrum pada Paparan Musik Mozart Lebih Tinggi Dibandingkan Dengan Paparan Musik Indonesia

2019 ◽  
Vol 11 (1) ◽  
pp. 18
Author(s):  
Agustina Mar'atus Sholichah ◽  
Hermanto Tri Joewono ◽  
Widjiati Widjiati
Keyword(s):  
Fetal Brain ◽  
Control Group ◽  
Pop Music ◽  
Test Results ◽  
Control Group Design ◽  
Religious Music ◽  
Group Design ◽  
Post Test ◽  
Music Stimulus ◽  
Hematoxylin Eosin

Background: Intelligence management can produce superior human resources with integrated brain. Mozart music stimulus during pregnancy has been shown to increase the number of neuron of the fetal brain. The study of pop and religious music needs to be improve because they are more popular in Indonesia. Objective: To analyze the differences of number of Neuron in the Cerebrum Rattus norvegicusoffspring that exposed to Mozart, Indonesian pop music and Indonesian religious music during pregnancy. Methods: An experimental study with a post-test only control group design. Groups divide into treatment music groups: Mozart, pop and religious. Treatment in a soundproof room for 1 hour, starting the 10th-day of pregnancy, intensity of 65 dB with a distance of 25 cm from the cage. The number of neuron was counted from HE brain preparations of the head Rattus norvegicusoffspring and analyzed using appropriate statistics test. Results: There were significant differences in the number of neuron of Rattus norvegicusoffspring in cerebrum between groups with p = 0,000 (mean Mozart music group 28.14 ± 3.02, Indonesian pop music 19.71 ± 1.80, Indonesian religious music 24.14 ± 2.91) and Mozart gave a higher number of neuron than Indonesia religious music and Indonesian pop music. Conclusion: Mozart music gave a higher number of neuron in the Cerebrum than Indonesian religious music and Indonesian pop music. Keywords: neuron; cerebrum; Mozart music; Indonesian music ABSTRAK Latar belakang: Pengelolaan kecerdasan otak yang terintegrasi akan menghasilkan SDM yang unggul. Stimulus musik Mozart selama kehamilan terbukti meningkatkan jumlah sel neuron di otak janin. Musik pop dan religi perlu dilakukan penelitian karena lebih populer di Indonesia. Tujuan: Menganalisis perbedaan jumlah sel neuron di Cerebrum Rattus norvegicusbaru lahir antara yang mendapat paparan musik Mozart, musik pop Indonesia dan musik religi Indonesia selama kebuntingan. Metode: Studi eksperimental dengan desain post test only control group. Kelompok perlakuan dibagi menjadi kelompok musik Mozart, musik pop Indonesia dan musik religi Indonesia. Perlakuan di ruang kedap suara selama 1 jam pada malam hari mulai hari ke-10 kebuntingan, intensitas 65 dB dengan jarak 25 cm antara kandang dan speaker. Jumlah sel neuron dihitung dari preparat pewarnaan Hematoxylin-Eosin otak anak Rattus norvegicusdan dianalisis dengan statistik yang sesuai. Hasil: Terdapat perbedaan yang signifikan pada jumlah sel neuron cerebrum Rattus norvegicus baru lahir antar kelompok dengan nilai p=0,000 (rerata kelompok musik Mozart 28,14±3,02, musik pop Indonesia 19,71±1,80 dan musik religi Indonesia 24,14±2,91) dan musik Mozart memiliki jumlah sel neuron lebih tinggi daripada musik religi Indonesia dan musik pop Indonesia. Kesimpulan: Kelompok musik Mozart memiliki jumlah sel neuron di cerebrum yang lebih tinggi dibandingkan kelompok musik Indonesia. Kata kunci: neuron; cerebrum; musik Mozart; musik Indonesia

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