scholarly journals Prevalensi Dengue Pada Mahasiswa Universitas Surabaya

2018 ◽  
Vol 6 (1) ◽  
pp. 45
Author(s):  
Dina Chamidah
Keyword(s):  
Socioeconomic Status ◽  
Abdominal Pain ◽  
Dengue Fever ◽  
Muscle Pain ◽  
Clinical Signs ◽  
Virus Transmission ◽  
Hemorrhagic Fever ◽  
Age Group ◽  
Life Threatening ◽  
The University

In Indonesia, dengue fever is still common. This has caused many troubled people in Indonesia including Surabaya, East Java. Clinical signs of dengue start from mild illness to life-threatening shock syndrome. So it takes a development of a treatment to combat dengue fever. The purpose of this study is to see the prevalence of dengue fever in students. The prevalence of dengue fever at the University of Surabaya accounted for 17%, as we approached 81 people among them 14 were infected with dengue hemorrhagic fever. There were 42 (65%) people suffering from headaches, 19 (29%) joints, 26 (40%) muscle pain and 16 (25%) had abdominal pain, and from 64 among the 18-23 age group. The data obtained is helpful in determining the therapeutic approach to infections that appear. Furthermore, demographic factors such as age, gender, socioeconomic status with dengue virus transmission are also being considered.

scholarly journals Clinico-epidemiological profile of paediatric dengue patients in a tertiary care hospital: a retrospective study in Visakhapatnam, Andhra Pradesh, India

2020 ◽  
Vol 7 (11) ◽  
pp. 4424
Author(s):  
Chilakala Padmavathy ◽  
B. Devi Madhavi ◽  
S. Suneetha ◽  
Suresh Babu Chaduvula
Keyword(s):  
Abdominal Pain ◽  
Dengue Fever ◽  
Tertiary Care ◽  
Dengue Shock Syndrome ◽  
Hemorrhagic Fever ◽  
Viral Disease ◽  
Care Hospital ◽  
Age Group ◽  
Hospital Data ◽  
Cross Sectional

Background: Dengue is a mosquito borne viral disease in the world with unpredictable clinical course and outcome. Though it is self-limiting in most of patients, the dengue hemorrhagic stage and dengue shock syndrome are life threatening.Methods: It is a retrospective cross-sectional observational record-based study conducted in King George Hospital in Andhra Medical College, Visakhapatnam, AP, India. Upon clinical suspicion, Dengue fever was confirmed by NS 1 antigen and/or Dengue antibody IgM, IgG in KGH laboratory in patients who were admitted in the hospital data was collected from records after ethical committee approval. Data of pediatric dengue positive cases in the age group ranging between 0-14 years from January 2018 - November 2018 were reviewed.Results: In this study the highest percentage of age group was found between 0-5 years. Fever was present in 100% cases, abdominal pain in 47% cases, rash, nausea/vomiting were found in 37%, headache in 12.35%, myalgia/ arthralgia or backache in 13.48%, retro orbital pain in <1% cases. Dengue fever (DF) was found in 46 % cases, dengue hemorrhagic fever (DHF) in 50% and dengue shock syndrome (DSS) in 3.9 cases.Conclusions: The study found among these 50% developed DHF and 46% DF and 3.9% DSS. Early admissions of pediatric cases can prevent major complications like DHF and DSS. The predominant complaints found were fever, vomiting and abdominal pain in paediatric group.

scholarly journals Factors associated with shock in children with dengue hemorrhagic fever

2016 ◽  
Vol 44 (5) ◽  
pp. 171 ◽  
Author(s):  
Erick F Kan ◽  
T H Rampengan
Keyword(s):  
Platelet Count ◽  
Abdominal Pain ◽  
Dengue Hemorrhagic Fever ◽  
Prospective Observational Study ◽  
Hemorrhagic Fever ◽  
Age Group ◽  
Hematocrit Level ◽  
Factors Associated ◽  
Independent Variables ◽  
Good Nutrition

Background Shock in dengue hemorrhagic fever (DHF) still con-stitutes an important problem in children. Predicting DHF patientswho will develop shock is difficult.Objective The aim of this study was to find out factors associatedwith shock in DHF.Methods This was a prospective observational study. Subjectswere children hospitalized from April to July 2000 who met theWHO criteria for DHF and had positive serological confirmation.Association between independent variables (age, gender, dura-tion of fever, abdominal pain, vomiting, hepatomegaly, plateletcount, hematocrit level, and nutritional status) and the dependentvariable (shock) was analyzed by logistic regression model..Results There were 85 children who met the eligibility criteriaconsisting of 50 (59%) boys and 35 (41%) girls with an averageage of 7.1 years (SD 2.88). Shock occurred in 42 (49%) children.Of the 42 children with shock, the age group of 5-9 years madeup the biggest group (57%) consisting of 23 (55%) boys and 19(45%) girls. Hepatomegaly was found in 32 (76%) children, ab-dominal pain and vomiting in 30 (71%) and 36 (86%) children,respectively, and good nutrition in 22 (52%) children. Shock oc-curred mainly on the fourth and fifth days (76%). Almost half ofthe patients (45% and 52%) had hematocrit level of 46-50% andplatelet count of 20,000-50,000/ml, respectively. By logistic re-gression analysis, it was found that duration of fever, abdominalpain, hematocrit level, and platelet count constituted indepen-dent factors correlating with shock in DHF.Conclusion Abdominal pain, fever lasting four to five days, hema-tocrit level of >46%, and platelet count of <50,000/μl were associ-ated with shock in DHF

scholarly journals Emphysematous pyelonephritis with Dengue hemorrhagic fever: A successful medical management of a fatal scenario

2017 ◽  
Vol 8 (5) ◽  
pp. 101-103
Author(s):  
Robin George Manappallil ◽  
Prathap Reddy Muthyala
Keyword(s):  
Dengue Fever ◽  
Hemorrhagic Fever ◽  
Severe Form ◽  
Medical Sciences ◽  
Emphysematous Pyelonephritis ◽  
Associated Gas ◽  
Acute Necrotizing ◽  
Life Threatening ◽  
History Of ◽  
Plasma Leakage

Emphysematous pyelonephritis is a life threatening acute necrotizing infection with associated gas formation involving the renal parenchyma and perinephric tissues. Dengue fever, according to the WHO, is the most rapidly spreading mosquito borne viral infection in the world. Dengue Hemorrgahic Fever is a more severe form of dengue fever and is characterized by fever, bleeding manifestations, plasma leakage and thrombocytopenia. This is a case of a 56 year old female, who presented with history of fever, headache, myalgia and dysuria; and was diagnosed to have emphysematous pyelonephritis with Dengue Hemorrgahic Fever. She was successfully managed with intravenous antibiotics and platelet transfusions, without any urological interventions. Asian Journal of Medical Sciences Vol.8(5) 2017 101-103

scholarly journals Dengue virus: A review

2022 ◽  
Vol 8 (4) ◽  
pp. 243-247
Author(s):  
Narinder Singh ◽  
Ajeet Pal Singh ◽  
Amar Pal Singh
Keyword(s):  
Public Health ◽  
Dengue Virus ◽  
Dengue Fever ◽  
Rna Virus ◽  
Hemorrhagic Fever ◽  
Health Concern ◽  
Virus Infections ◽  
Public Health Concern ◽  
Viral Illness ◽  
Life Threatening

Dengue fever is a mosquito-borne viral illness that is quickly spreading over the globe, with significant death and morbidity rates. Dengue fever is an acute viral infection transmitted by Aedes mosquitos and caused by an RNA virus from the Flaviviridae family. The symptoms might vary from asymptomatic fever to life-threatening complications including hemorrhagic fever and shock. Although dengue virus infections are normally self-limiting, the disease has become a public health concern in tropical and subtropical countries. Dengue fever is a major public health concern owing to its rapid worldwide spread, and its burdens are now unmet due to a lack of accurate therapy and a simple diagnostic approach for the early stages of illness.

scholarly journals Profile of Dengue High Fever in Blitar City at 2015-2017

2018 ◽  
Vol 6 (3) ◽  
pp. 260 ◽  
Author(s):  
Endah Tri Suryani
Keyword(s):  
Dengue Fever ◽  
Case Series ◽  
Hemorrhagic Fever ◽  
Age Group ◽  
Health Profile ◽  
Fever Case ◽  
Total Death ◽  
Group 5 ◽  
The City ◽  
Observational Descriptive Study

Background: Dengue Hemorrhagic Fever (DHF) remains a health problem in Indonesia where the number of cases reported in 2015 was 129,650 cases with a total death toll of 1,071 people. The city of Blitar is the region with the 13th highest dengue fever case in East Java Province. Purpose: This study aims to describe cases of dengue fever in the city of Blitar. Methods: This study is an observational descriptive study with a case series approach. The data used in this study is dengue fever data in the East Java Health Profile for 2015-2017. Results: The majority of dengue fever occurred in the age group 5-14 years (46.72%). Most cases of dengue fever occur in men (51.19%). The city of Blitar is an area with cases of dengue fever which is high each year with the Incidence Rate (IR) in 2016 reaching 189 per 100,000 population. The increase in cases of dengue fever is not in line with the increase in rainfall in the city of Blitar. Jumantik has 166 people spread across 21 regions, but the free larvae (ABJ) from Blitar is still 79%, far from the success indicator of 95%. Conclusion: Blitar City is an endemic area of DHF that has stratification of 20 hamlets. The pattern of dengue fever in Blitar City in 2015-2017 was the highest in men and in the age group of 5-14 years.

scholarly journals Description of Extraordinary Events of Dengue Hemorrhagic Fever In Belu Regency, East Nusa Tenggara Province 2020

2021 ◽  
Vol 9 (3) ◽  
pp. 172
Author(s):  
Werenfridus Leonardo Nando Luan
Keyword(s):  
Dengue Fever ◽  
Dengue Hemorrhagic Fever ◽  
Endemic Area ◽  
Case Series ◽  
Secondary Data ◽  
Hemorrhagic Fever ◽  
Age Group ◽  
District Health ◽  
Series Design ◽  
Group 5

Belu Regency is located in the province of East Nusa Tenggara (NTT), Indonesia and is an endemic area for dengue fever. Nationally, until June 2020, there were 16,320 cases of dengue fever with a CFR of 0.009%, while in Belu Regency there were 820 cases recorded until June 2020 with a CFR of 0.97%. This study aims to describe the outbreak of DHF by person, place and time as well as the distribution of cases in Belu Regency. this research is descriptive observational with case series design. The source of research data is secondary data on dengue cases obtained from the 2016-2019 Dengue Hemorrhagic Fever (DHF) Report and the DHF outbreak report in January-June 2020, the Belu District Health O ce. DHF cases in Belu Regency until June 2020 were 820 cases with symptoms of fever 2-7 days by 100% and supported by laboratory platelet examinations of 73%. The highest IR rate until June 2020 is 367 per 100. 000 residents with a CFR of 0.97% spread over 12 sub-districts of Belu Regency. The highest IRs (>20 per 10,000 population) are Atambua city, South Atambua, East Tasifeto, West Atambua, Kakuluk Mesak and West Tasifeto subdistricts. The majority of DHF in the age group 5-14 years 521 cases (27.1%) with female sex as many as 495 cases (51.51%). DHF cases were found since the first epidemiological week at the beginning of the year with peak cases at the 13th week. Belu Regency Is a dengue endemic area with an IR of 367/100,000 population with a CFR of 0.97%. The highest cases were in the 5-14 year age group and spread across 12 sub-districts of Belu Regency. 

CASE REPORT ON DENGUE ASSOCIATED HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS- A RARE PRESENTATION.

2021 ◽  
pp. 7-8
Author(s):  
K. Shivaraju ◽  
Manideepa Pogaku ◽  
Mandhala Saikrishna
Keyword(s):  
Dengue Fever ◽  
Hemophagocytic Lymphohistiocytosis ◽  
Supportive Therapy ◽  
Hemorrhagic Fever ◽  
Severe Form ◽  
High Grade Fever ◽  
Rare Presentation ◽  
Life Threatening ◽  
The Common

Dengue fever in its severe form has signicant morbidity and mortality worldwide. Apart from the common complication of dengue fever, infection induced HLH is a rare and life-threatening complication associated with the viral infection. Here we are presenting a case of 28 years old male with no comorbidities and complains of high-grade fever, myalgia, nausea and vomiting, black stools from 5 days. Based on all investigations patient was diagnosed with hemophagocytic lymphohistiocytosis secondary to dengue hemorrhagic fever. Then treated with appropriate medications and supportive therapy, discharged, and advised follow-up on OPD basis.

scholarly journals Selection for Virulent Dengue Viruses Occurs in Humans and Mosquitoes

2005 ◽  
Vol 79 (2) ◽  
pp. 853-859 ◽  
Author(s):  
Raymond Cologna ◽  
Philip M. Armstrong ◽  
Rebeca Rico-Hesse
Keyword(s):  
Dengue Fever ◽  
Dengue Hemorrhagic Fever ◽  
Virus Transmission ◽  
Indirect Evidence ◽  
Hemorrhagic Fever ◽  
Viral Disease ◽  
Southeast Asian ◽  
Severe Dengue ◽  
Dengue Viruses ◽  
Dengue Disease

ABSTRACT Dengue is the most common mosquito-borne viral disease in humans. The spread of both mosquito vectors and viruses has led to the resurgence of epidemic dengue fever (a self-limited flu-like syndrome) and the emergence of dengue hemorrhagic fever (severe dengue with bleeding abnormalities) in urban centers of the tropics. There are no animal or laboratory models of dengue disease; indirect evidence suggests that dengue viruses differ in virulence, including their pathogenicities for humans and epidemic potential. We developed two assay systems (using human dendritic cells and Aedes aegypti mosquitoes) for measuring differences in virus replication that correlate with the potential to cause hemorrhagic dengue and increased virus transmission. Infection and growth experiments showed that dengue serotype 2 viruses causing dengue hemorrhagic fever epidemics (Southeast Asian genotype) can outcompete viruses that cause dengue fever only (American genotype). This fact implies that Southeast Asian genotype viruses will continue to displace other viruses, causing more hemorrhagic dengue epidemics.

scholarly journals Blood glucose promotes dengue virus infection in the mosquito Aedes aegypti

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Shih-Che Weng ◽  
Po-Nien Tsao ◽  
Shin-Hong Shiao
Keyword(s):  
Blood Glucose ◽  
Aedes Aegypti ◽  
Dengue Virus ◽  
Viral Replication ◽  
Dengue Fever ◽  
Virus Transmission ◽  
Hemorrhagic Fever ◽  
Co Morbidity ◽  
The Impact ◽  
Blood Meals

Abstract Background Dengue fever is the most rapidly spreading mosquito-borne viral disease globally. More than 2.5 billion people live in dengue-endemic areas. Previous studies suggested an interrelationship between diabetes mellitus (DM) and dengue hemorrhagic fever (DHF). Conversely, glycolysis is a critical metabolic pathway for optimal dengue virus (DENV) replication. However, little is known concerning the effect of glucose on DENV replication in mosquitoes. In this study, we investigated the impact of glucose on DENV replication in mosquitoes Aedes aegypti. Methods Mosquitoes (Ae. aegypti UGAL/Rockefeller strain) were orally infected with DENV (serotype 2, 16681 strain) through infectious blood feeding. The DENV infection and transmission rates were determined by examining mosquito bodies and saliva, respectively, for DENV positivity at different time points after infection. In addition, a reverse genetic approach was applied by introducing double-stranded RNA against genes of interest into the mosquitoes to inhibit gene expression. Results Our data revealed a significant increase of DENV genome levels in mosquitoes consuming an infectious blood meal supplemented with glucose, suggesting that blood glucose is an important factor for viral replication. Interestingly, a significant increase of DENV E protein levels was detected in the saliva 4 days faster in mosquitoes that consumed infectious blood meals supplemented with glucose than in those consuming infectious blood meals alone. Furthermore, we perform RNAi to silence AKT or TOR and investigate the molecular mechanism regulating the glucose-mediated enhancement of viral replication. Silencing of AKT or TOR significantly reduced DENV titers in mosquitoes. Conclusions This study suggested that blood glucose is beneficial to DENV replication and that it facilitates virus transmission in mosquitoes via AKT and TOR signaling. Therefore, our results strengthen our understanding of dengue fever and DM co-morbidity and possibly reveal new targets for specific antiviral therapies. Graphical abstract

scholarly journals Knowledge, awareness and attitude towards dengue fever outbreaks in the summer

2018 ◽  
Vol 5 (4) ◽  
pp. 772
Author(s):  
Rawan Almuhanna ◽  
Abdulrahman Alobudi ◽  
Saud Alazdi ◽  
Hammam Alghamdi ◽  
Muhab Hindi ◽  
...  
Keyword(s):  
Dengue Fever ◽  
Computer Literacy ◽  
Public Health Problem ◽  
Dengue Shock Syndrome ◽  
Hemorrhagic Fever ◽  
World Population ◽  
Healthcare Education ◽  
Life Threatening ◽  
The Impact ◽  
Status Level

Dengue fever is a life-threatening viral infection that has been a public health problem. It is estimated that almost more than one half of the world population live in countries where dengue fever is endemic. Among affected individuals, about 5% develop the fatal dengue shock syndrome and dengue hemorrhagic fever, and almost 20,000 patients die annually with these conditions. Despite the magnitude of the problem, dengue fever is a preventable disease. Prevention can be carried out by elimination of inhabitant mosquitoes, vaccination of vulnerable individuals, and regular health education particularly during outbreaks. Many literatures studies were conducted to evaluate the impact of healthcare education on dengue fever prevention, and many researchers studied the population awareness and attitudes about the disease. Knowledge and awareness varied among different studies, and some factors were reported to influence this knowledge such as gender, socioeconomic status, level of education, and computer literacy. The attitudes also differed among the studies and did not seem to be correlated with the population knowledge about the disease. This article will review the knowledge, awareness, and attitudes among different countries towards dengue fever outbreaks in the summer.

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