scholarly journals The effect of phytoextract containing ecdysteroids and flavonoids on the metabolic parameters of pigs and white mice

2020 ◽  
Vol 21 (5) ◽  
pp. 597-604
Author(s):  
A. A. Ivanovsky ◽  
N. A. Latushkina ◽  
E. Yu. Timkina
Keyword(s):  
Total Protein ◽  
Blood Parameters ◽  
Daily Weight Gain ◽  
Control Group ◽  
Average Weight ◽  
Laboratory Mice ◽  
Daily Growth ◽  
Extractive Substances ◽  
Calcium Phosphorus ◽  
Negative Effect

The purpose of the research is to study the effect of extractive substances from a complex of herbs (R. Carthamoides, S. Coronate, F. ulmaria )on individual indicators of the metabolism of laboratory mice, pregnant sows and piglets obtained from them. A phytoextract containing ecdysteroids and flavonoids was orally administered to white mice ( three experimental and one control group of 15 mice) in doses of 0.1; 0.2 and 0.3 ml during 14 days that provided an increase in the average daily weight gain by 20.8-48.5% (P <0.05) in comparison with the control. The introduction into the diet of pregnant sows (three experimental groups and one control group of 10 sows) of an additive containing a phytoextract once a day at doses 3, 5 and 10 grams per head within 30 days before farrowing did not cause deviations from the norm of the studied biochemical blood parameters (total protein, albumin, cholesterol, calcium, phosphorus, magnesium, urea, creatinine, ALT, AST). The blood parameters of sows in the experimental groups characterizing the metabolic status of the organism were within the reference limits: total protein 60.7±0.4-62.0±0.3 g/l; albumin 44.2±0.4-52.7±1.8 g/l; cholesterol 2.14±0.04-2.90±0.01 mmol/l; Ca 2.50±0.05-2.62±0.01 mmol/l; P 2.91±0.0-3.16±0.04 mmol/l; Mg 0.92±0.02-1.28±0.01 mmol/l; AST 27.6±2.4-29.3±0.5 units; ALT 23.7±1.1-26.9±1.3 units; urea 4.8±0.2-7.9±0.5 mmol/l; creatinine 101.2±3.5-110.0±2.1 mkmol/l. The number of newborn piglets obtained from sows in the experimental groups exceeded the indicator in the control (127 heads) by 6.2%, of which live by 10.6% (in the control, 113 heads), the number transferred for weaning by 11.2% (in control 107 heads), gross growth by 9.8% (control 887 kg). The rest of the studied parameters of piglets (average weight of a piglet during transfer, average daily growth, survivability) did not differ significantly from the control (P> 0.05). It has been established that the phytoextract had an anabolic effect on white mice, did not cause a negative effect on the studied biochemical parameters of metabolism in pregnant sows, and contributed to an increase in the number of live newborns in comparison with the control.

scholarly journals The influence of different amounts of zinc citrate on blood biochemical indices and productivity of rabbit organism

2019 ◽  
Vol 21 (96) ◽  
pp. 65-70
Author(s):  
Ya. V. Lesyk ◽  
M. M. Khomyn ◽  
I. V. Luchka ◽  
N. O. Bosanevich
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Total Protein ◽  
Body Weight Gain ◽  
Cholesterol Content ◽  
Daily Weight Gain ◽  
Control Group ◽  
Mineral Supplement ◽  
Daily Growth ◽  
Experimental Group

Deficiency of micro- and macronutrients in the organism of young rabbits causes disorders of metabolism and decreased productivity. Inclusion of essential micronutrients made by nanotechnology to the rabbit diet can eliminate this problem. Therefore, the purpose of our research was to investigate the influence of different amounts of zinc citrate in combination with cobalt and chromium citrates on the biochemical processes in the organism and the productivity of rabbits from 62 to 86 days of age. Researches were performed on rabbits 40 days of age, weighing 1.2–1.4 kg. The animals of the experimental groups were fed with fodder ration of the control group and during the day were fed with cobalt citrate in the amount of 40 μg Co/kg of body weight, chromium citrate – 40 mcg Cr/kg of body weight and zinc citrate, calculated respectively in I, II and III of experimental groups 0.25; 0.50 and 0.75 mg Zn/kg of body weight. In the preparatory period – on the 10th day and in the experimental on the 12th, 24th and 36th days of drinking the supplements in 4 animals from the group blood samples were taken for biochemical researches. Body weight gain was also determined by weighing. It was found that in the blood of animals of the first experimental group on the 12th day of drinking mineral additives increased the cholesterol content on 28.8%, on 24th day – decrease by 39.1% and increase – creatinine by 11.6%, and on 36th day – increase in blood of total protein on 12.3%, increase of alkaline phosphatase activity by 23.0%, creatinine content by 15.5% and average daily growth by 9.4%. A similar additive containing zinc citrate of 0.50 mg Zn/kg of body weight in the blood of rabbits of the second experimental group increased the activity of ACAT by 12 and 24 days, respectively, by 37.3 and 22.1%, respectively, and reduced their cholesterol content by 33.9 and 63.1% compared to the control. Whereas in the same group the growth of ALT activity was noted by 23.7%, and the average daily increase was higher than the control indicator by 7.9% 36 days of the research in comparison with the control group. The high content of zinc citrate in the mineral supplement (0.75 mg Zn/kg) in the blood of rabbits of the third experimental group contributed to the increase of the total protein concentration in all periods of the research, AST activity increased by 26.1% on the 24th day, AAT by 34.9% and the content of triacylglycerols and cholesterol was decreased, while on the 36th day the AAT activity increased by 20.3%, under these conditions, the average daily weight gain of rabbits was the highest and amounted to 38.4 g, which was 12.9% higher than the control. Therefore, the additive in the content of citrates of Co and Cr in the amount of 40 μg/kg of body weight and Zn citrate in the amount of 0.75 mg Zn/kg of body weight contributed to the improvement of metabolic processes and increase of growth indices, which may indicate the dose-dependent influence of the additives used in the rabbit young body.

scholarly journals Efficiency of zeolite basis preparation in fattening lambs diet

2012 ◽  
Vol 28 (3) ◽  
pp. 545-552 ◽  
Author(s):  
J. Stojkovic ◽  
Z. Ilic ◽  
S. Ciric ◽  
B. Ristanovic ◽  
M.P. Petrovic ◽  
...  
Keyword(s):  
Natural Zeolite ◽  
Dry Matter ◽  
Test Group ◽  
Daily Weight Gain ◽  
Control Group ◽  
Average Weight ◽  
Sheep Milk ◽  
The Impact ◽  
Experimental Group ◽  
At Will

The paper presents the results of a research on the impact of products based on natural zeolite on the production results of fattening lambs. The experiment involved two groups of lambs (the control - C and experimental - E groups), each consisting of 15 heads, for a period of 90 days. The meal was made from sheep milk, feed mixtures for fattening lambs and meadow hay. The test group lambs, unlike the ones from the control group, were given mixtures based on natural zeolite. Min-a-Zel S mixture (in the form of 25% composite) was fed to lambs from birth till their 14th day of life, directly into the mouth, once a day (before the morning feed), in the amount of 10 ml. Min-a-Zel Plus was given to them from their 15th day of life, together with the feed mixture (0.5%). Feeding was at will. The average weight of lambs at the end of the experiment, in accordance with the sequence of treatments (C:E) was 24.40:26.94 kg (P <0.01). Daily weight gain of lambs, during the experiment, was 229:256 g and in the experimental group it was by 27g or 11.79% higher (P <0.01). The test group lambs had a better utilization of dry matter, protein and energy, which justifies the use of products based on natural zeolite in fattening lambs.

EVALUATION OF MEAT IN THE INFANT DIET

PEDIATRICS ◽  
1952 ◽  
Vol 10 (4) ◽  
pp. 463-473
Author(s):  
HOWARD M. JACOBS ◽  
GEORGE S. GEORGE
Keyword(s):  
Total Protein ◽  
Infant Nutrition ◽  
Physical Growth ◽  
Morbidity Rate ◽  
Control Group ◽  
Average Weight ◽  
Protein Requirements ◽  
Protein Levels ◽  
Young Infants ◽  
Significant Difference

A commercially prepared lean meat was fed to young infants as a supplement to a diet already adequate in all food factors. In those infants first fed meat under 2 months of age, there was improvement in physical growth as determined by weight and height measurements. The same group demonstrated an improvement in hemoglobin levels; the elimination of the physiologic drop in total protein levels of the serum, with a prompt sustained rise in values, the greater part of which was composed of the globulin fraction. In those infants first fed meat after 2 months of age, there was a slight improvement in average weight gain, but no significant difference was noted in other body measurements, total protein, albumin or globulin fractions, or hemoglobin levels. Illness rates for the two years of the study demonstrated a 40% lower morbidity rate in the meat-fed group as compared to the control group. In striving for the optimum in infant nutrition protein requirements should be evaluated both quantitatively and qualitatively.

scholarly journals Plasma Calcium Levels in Pregnant Asian Women

1976 ◽  
Vol 13 (1-6) ◽  
pp. 339-344 ◽  
Author(s):  
Nina Polanska ◽  
R. A. Dale ◽  
M. R. Wills
Keyword(s):  
Vitamin D ◽  
Alkaline Phosphatase ◽  
Dietary Intake ◽  
Total Protein ◽  
Plasma Calcium ◽  
Asian Women ◽  
Control Group ◽  
Calcium Phosphorus ◽  
And Control ◽  
Endogenous Synthesis

Plasma calcium, phosphorus, alkaline phosphatase, total protein, and albumin were measured during pregnancy in a group of Asian women living in the south of England and in a control group. The Asian women had slightly lower mean plasma calcium concentrations than the control group. Exposure of Asian women to sunshine appeared to be low, and it was inferred that they probably had little endogenous synthesis of cholecalciferol as a result. Both Asian and control subjects ingested similarly low amounts of vitamin D. The Asian women consumed greater amounts of phytate and vegetable fibres than the controls, and it is suggested that these substances may reduce absorption of insoluble lipids (including cholecalciferol) and calcium in a setting where the dietary intake and endogenous synthesis of vitamin D are already borderline for the subjects' requirements.

scholarly journals Ferric citrate is a safe and digestible source of iron in broilers and piglets

PeerJ ◽  
2021 ◽  
Vol 9 ◽  
pp. e12636
Author(s):  
Klaus Männer ◽  
Hannah Lester ◽  
Eliana Henriquez-Rodriguez
Keyword(s):  
Adverse Effects ◽  
Dose Group ◽  
Block Design ◽  
Blood Parameters ◽  
Negative Control ◽  
Ferric Citrate ◽  
Daily Weight Gain ◽  
Control Group ◽  
Weaned Piglets ◽  
Inclusion Rate

Background Iron (Fe) is traditionally supplemented in poultry and swine diets using inorganic forms (e.g. sulfates, oxides). However, research suggests that organic sources are more beneficial due to greater bioavailability. In this paper, we present results from four studies aimed at assessing ferric citrate (CI-FER™, Akeso Biomedical Inc., Burlington, MA, USA) as a safe and effective source of Fe for broilers and piglets. Methods A total of four studies were performed in Germany following standard farming practices for each species. One study in day-old broiler chicks and one study in weaned piglets were designed as target animal safety studies where animals were randomly allocated to one of three treatment groups: a negative control group, the proposed dose group and a multifold dose group. Broilers and pigs were fed the experimental diets for 35 and 42 days, respectively. In each study, average daily feed intake, average daily weight gain and feed conversion ratio were measured, and blood samples were taken at study end for routine biochemistry and haematology. The other two studies were designed to evaluate different sources of dietary Fe for weaned piglets bred and managed under standard farm conditions. All piglets received routine Fe injections (200 mg Fe dextran, intramuscular) on day 3 of age, as well as the experimental diets for 42 days. In both studies, performance parameters were measured. In one study, Fe digestibility and serum Fe, superoxide dismutase and haptoglobin were also measured. In all studies, the general health status of the animals was monitored daily and all culls and mortality recorded. Each study followed a complete randomised block design. Results In broilers, ferric citrate was well tolerated up to 2,000 mg/kg feed (×10 the recommended inclusion rate) and no adverse effects on growth, blood parameters or mortality were observed. In piglets, ferric citrate was well tolerated up to 5,000 mg/kg feed (×10 the recommended inclusion rate) with no adverse effects on growth, blood parameters or mortality. In addition, piglets fed ferric citrate performed significantly better than animals fed the negative control diet (containing only endogenous Fe) and those fed inorganic forms of Fe. Moreover, piglets fed ferric citrate demonstrated improved Fe digestibility and improved oxidative status. Altogether, these findings show that ferric citrate is a safe and easily digestible source of dietary Fe for broilers and piglets.

scholarly journals Effects of probiotic dietary supplementation on diarrhoea patterns, faecal microbiota and performance of early weaned calves

2010 ◽  
Vol 55 (No. 10) ◽  
pp. 494-503 ◽  
Author(s):  
J. Jatkauskas ◽  
V. Vrotniakiene
Keyword(s):  
Weight Gain ◽  
Enterococcus Faecium ◽  
Control Diet ◽  
Dietary Supplementation ◽  
Daily Weight Gain ◽  
Control Group ◽  
Average Weight ◽  
Probiotic Supplementation ◽  
Positive Effects ◽  
Probiotic Product

Twenty Lithuanian Black-and-White calves (10 bulls, 10 heifers) were used to evaluate the effects of the supplemental probiotic product, Enterococcus faecium M74 (2.4 g/day/calve), added to fresh milk and skimmed milk in a 56 day-study. The probiotic was administered by dietary supplementation to first group of calves and their respective pens (probiotic group), whereas the second group (control group) received no probiotic supplementation. The results of this trial indicate positive effects of the probiotic product Enterococcus faecium M74. The actual percentage of calves with diarrhoea was reduced from 50 % to 20% among the calves fed the pre-and probiotic diet. Probiotic supplementation reduced the faecal count of clostridia and enterococci. The calves fed Enterococcus faecium M74 weighed more at 20, 40 and 62 days of age by 4.9%, by 9.7% (P &lt; 0.05) and by 9.4% (P &lt; 0.01), respectively, than the control calves. The calves fed Enterococcus faecium M74 had increased daily weight gains compared with the calves not fed a probiotic product. The average weight gain and the daily weight gain of the probiotic-supplemented calves were by 7.8 kg (P &lt; 0.01) and by 0.14 kg higher (P &lt; 0.01) compared with the control calves. The calves given the Enterococcus faecium M74 also had forage and total DM intakes that were numerically higher than those fed the control diet, without any additive. During the 56 days experimental period, the average feed conversion rate was improved by 12.9% in the probiotic-treated group.

scholarly journals The influence of hempseed cake on production traits, metabolic profile and antioxidant status of Merinolandschaf lambs

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Zvonko Antunović ◽  
Željka Klir Šalavardić ◽  
Zvonimir Steiner ◽  
Mislav Đidara ◽  
Suzana Ćavar ◽  
...  
Keyword(s):  
Metabolic Profile ◽  
Antioxidant Status ◽  
Blood Parameters ◽  
Daily Weight Gain ◽  
Control Group ◽  
Production Traits ◽  
Blood Concentrations ◽  
Live Body Weight ◽  
Main Protein ◽  
Experimental Group

AbstractThe aim of this study was to investigate the effect of hempseed cake on production traits, metabolic profile and antioxidant status of lambs. The research was conducted on 20 Merinolandschaf lambs of similar live body weight (24.03 kg ± 2.22 and 24.06 ± 1.84 kg in control and experimental group, respectively). The experiment started after the weaning of lambs at their average age of 70 days. Lambs were divided by gender (50% male: 50% female) and then allocated in two groups. The research lasted for 30 days during the fattening period. Lambs in the control group were fed with feed mixtures, where main protein source was soybean meal and extruded soybean (SB), while lambs in the experimental group were fed feed mixtures in which soybean was replaced by hempseed cake (HSC) at 12% of dry matter. Higher values of daily weight gain (P<0.05) compared to SB lambs were observed from the 15th to 30th day. HSC lambs showed no significant differences in hematology and biochemical blood parameters, except for lower (P<0.001) urea concentrations on days 15th and 30th, as well as higher (P<0.05) Mg concentrations in serum on the 30th day. Hempseed cake in lambs′ diets did not influence (P>0.05) activity of the enzymes, like AST, ALT, ALP, GGT and CK, as well as SOD and GPx enzymes, thus not affecting the antioxidant status of lambs′ blood. Concentrations of DHA and n-3 fatty acids were higher (P<0.05) in HSC group than in SB group. The present study confirmed that the inclusion of HSC as soybean replacement up to 12% in the lambs’ diet is justified when considering production traits, metabolic profile and antioxidant status of Merinolandschaf lambs.

scholarly journals Infection of sheep with Strongyloides papillosus: The effect of intensity of parasitic infection as well as therapy with albendazole on certain biochemical parameters in the blood of sheep

2015 ◽  
Vol 69 (1-2) ◽  
pp. 41-61
Author(s):  
Blagoje Dimitrijevic ◽  
Slavoljub Jovic ◽  
Milanka Jezdimirovic ◽  
Dragan Bacic ◽  
Mila Savic ◽  
...  
Keyword(s):  
Lactate Dehydrogenase ◽  
Total Protein ◽  
Biochemical Parameters ◽  
Total Bilirubin ◽  
Parasitic Infection ◽  
Infection Intensity ◽  
Total Activity ◽  
Control Group ◽  
Growth Trend ◽  
Calcium Phosphorus

The objective of this work was to investigate certain biochemical parameters in the blood of sheep in conditions of different intensity of parasitic infection with Strongyloides papillosus, and also after the therapy with albendazole. The research was carried out on the sheep of Wurtemberg breed (n = 30) in which there was determined low, medium and high intensity of parasitic infection with S. papillosus. The control group (n = 10) consisted of the sheep that were negative to the presence of the parasitic infection. The degree and type of changes were monitored by determining the concentration of glucose, total protein, albumin, Albumin/Globulin ratio, AST, urea, total bilirubin, calcium, phosphorus, lactate dehydrogenase (LDH) total activity and isoenzyme distribution LDH1-5. On the basis of the obtained results it was concluded, through isoenzyme distribution of lactate dehydrogenase, that parasitic infection with S. papillosus can cause damage to the liver, heart muscle and lungs, while after the therapy with albendazole, the most affected organ is the liver. The concentration of glucose, total protein and albumin linearly decreased with the increase of intensity of the parasitic infection (p < 0,05), and after the therapy with albendazole, a drop in concentration of these parameters was at a statistically significantly higher level (p< 0,01). AST activity as well as the concentration of urea and total bilirubin grew linearly along with the intensity of the parasitic infection (p < 0,05). After the therapy with ABZ, AST activity and concentration of total bilirubin were at a statistically significantly higher level (p < 0,001), while urea concentration kept the same level as in the case of the parasitic infection. The values of calcium concentration (p > 0,05) as well as phosphorus (p < 0,05) linearly decreased with the parasitic infection intensity growth. Trend towards the decline of the concentration of these macroelements continues even after the therapy with albendazole (p < 0,001). Considering our previous research in the field of oxidative stress, a phenomenon that is fundamentally related to the changes determined in this work, we strongly recommend that besides antihelmintics, preparations with antioxidative properties should be used in antiparasitic protocols as well. <br><font color="red"><b> This article has been retracted. Link to the retraction <u><a href="http://dx.doi.org/10.2298/VETGL190125001E">10.2298/VETGL190125001E</a><u></b></font>

scholarly journals Use of probiotics instead of antibiotics in broiler production

2019 ◽  
Vol 29 (4) ◽  
pp. 359-370
Author(s):  
MJ Alam ◽  
Z Ferdaushi
Keyword(s):  
Body Weight ◽  
Uric Acid ◽  
Growth Performance ◽  
Total Protein ◽  
Blood Parameters ◽  
Abdominal Fat ◽  
Control Group ◽  
Broiler Chicks ◽  
Feed Conversion ◽  
Finisher Diets

Effects of different available commercial probiotics on growth performance and blood parameters were evaluated. To achieve the objectives, a total of 198 one-day-old Hubbard Isa Starbro broiler chicks were raised over 28 days. Chicks were wing-banded, weighed individually and randomly allocated into six equally major groups each having three replicates. Broilers of group T1 (control group) were fed the starter and finisher diets. The broilers of groups T2 was fed the control starter and finisher diets supplemented with antibiotic and groups T3-T5 were fed 4 different commercially available probiotics (T3-Guardizen-M, T4-Protexin and T5-Poultry star sol in drinking water. Weekly body weight, feed consumption and feed conversion were recorded during experimental period. Blood parameters at 4 weeks of age including packed cell volume (PCV), haemoglobin (Hb), total protein, albumin, triglycerides, high density lipoprotein (HDL), uric acid, cholesterol, glucose, intestinal microflora, pH and color properties of meat were determined. All birds were kept under similar environmental, managerial and hygienic conditions. Probiotic supplementation significantly increased the body weight and daily weight gain of broiler chicks at 28 days (p<0.05). Improved feed conversion was noticed in birds fed a diet supplemented with probiotic. The effects of probiotics on carcass and some internal organs were measured and results shows that feeding broilers with probiotics have significant effects (P < 0.05) on dressed carcass weight, abdominal fat, breast, thigh and liver while it appeared insignificant on gizzard (P> 0.05). The lower percent of abdominal fat and the higher percent of dressed carcass, breast and thigh were observed in experimental probiotic(s) groups. pH and meat color did not affect among treatments. There was lower mortality rate in probiotics among groups. Moreover, there was no significant change for Hb, PCV, total protein and albumin concentrations among different groups. Also, total protein, lipids and albumin concentrations were not affected by probiotic(s) supplementation. In addition, different probiotics showed a significant decrease (p<0.05) in triglycerides, cholesterol and uric acid concentration compared to control group. Birds supplemented with probiotics had higher number of lactobacilli but lower number of colibacilli compared to the control. It can be concluded that use of selected commercial probiotic(s) resulted in improved growth performance and carcass yields, and reduced serum cholesterol and uric acid in broiler chickens. Moreover, supplementation of the probiotic(s) to broilers had no detrimental effect on their growth performance and blood parameters. Therefore, usage of these probiotic(s) bacteria as antibiotic alternatives in poultry nutrition can be recommended. Progressive Agriculture 29 (4): 359-370, 2018

scholarly journals Effect of Sublethal Dose of Dichlorvos on the Biochemical Parameters of African Catfish

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Achikanu CE ◽  
Ani ON
Keyword(s):  
Total Protein ◽  
Biochemical Parameters ◽  
Liver Enzymes ◽  
Clarias Gariepinus ◽  
Sublethal Dose ◽  
Control Group ◽  
Average Weight ◽  
African Catfish ◽  
Serum Total Protein ◽  
Sublethal Concentrations

The present study investigated the effects of sublethal concentrations of dichlorvos on liver marker enzymes (aspartate aminotransferase, alanine aminotransferase and alkaline phosphatase), acid phosphatase (ACP), serum total protein (STP), bilirubin, urea and creatinine in African Catfish (Clarias gariepinus) juveniles at sub acute period under laboratory conditions. A total of 90 juveniles of Clarias gariepinus with average weight and length of 200.15 ± 0.09g and 26.00 ± 0.00cm respectively were kept in three experimental groups of 30 per group in triplicate of 10 fishes. Groups 1 and 2 were exposed to dichlorvos at dosages of 21 and 43mg/l respectively and group 3 served as control for 15 experimental days. Analyses were carried out on days 1, 5, 10 and 15. From the results, there was no significant changes in the biochemical parameters tested on day 1 of the experiment but levels of the liver enzymes, ACP and bilirubin increased significantly (p<0.05) on other experimental days when compared with the control group. However, there was insignificant increase in the urea level and also a non-significant decrease in the creatinine and Serum total protein (STP) levels of the experimental groups when compared with the control group. From the analyses and observations made, we conclude that the administration of sublethal concentrations of dichlorvos to African catfish induced some damages to the liver which affected the levels of the liver enzymes and the increase in ACP level is indicative of carcinogenicity.

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