scholarly journals ЛОГІСТИЧНА ДІЯЛЬНІСТЬ ПІДПРИЄМСТВА В УМОВАХ ГЛОБАЛІЗАЦІЇ

Author(s):  
Олена М. Сохацька

The paper provides insights into logistics specifics and its key elements at a modern enterprise in the context of globalization along with discussing the interrelation of modern marketing tools and possibilities of its implementation within enterprise logistics activities. It is argued that consumer logistics is the most critical element in the enterprise logistics system. In contemporary market environment, consumer demands in the industrial market are not limited to meeting the manufacturers’ needs for raw materials and high quality materials and products but also involve efforts to ensure timely delivery as well as the access to flexible pricing plans for logistics services at a minimum total cost. It is emphasized that responding to the above requirements and meeting the consumer expectations challenge the design and implementation of relevant marketing activities and policies. The modern marketing and logistics concept seeks to address the following objectives: developing and planning product assortment; information flows management; product turnover and sales management; advertising and sales promotion, etc. The findings demonstrate that the company effective e-marketing management strategy in the logistics frameworks will boost its long-term competitiveness compared to other companies operating in the market. It is argued that a competitive e-sales management strategy should be based on a thorough analysis of the company's current competitive position in order to improve it. In this context, the company's competitive position is determined by its competitive advantages in the Internet and this market attractiveness to manufacturing and business activities of the enterprise. The best practice from the countries with developed economies shows that in modern realia the company succeeds if it focuses on the customer, provides high quality products and services, and promotes up-to-date management methods. Effective communication with a customer is a crucial and integral part of the company tender procurement process, being a starting and a final stage of product output. By the results of the study it is concluded that meeting the customer expectations is a key goal for modern enterprises.

Author(s):  
Elena Lytvynenko ◽  
◽  
Taisiya Kozlova ◽  

The changeable and unpredictable development of the enterprises’ external environment is one of the appearance causes of various types of business activities' risks, including logistics. The purpose of this article is to develop recommendations on improving the risk management of enterprises’ logistics activities in the context of instability. Achieving this goal requires consideration of the main stages of this process regarding the logistics activities' risks, providing advices on improving the process of risk management of logistics orientation. The article explores the process of analyzing the logistics activities' risks of the enterprise. Proceeding from the theoretical provisions of management and summarizing the practical experience of research in the field of systematic analysis of the enterprises' logistics activities risks, there are traced the organization's peculiarities of such analysis, and the main directions of its further improvement are proposed. All actions in the article, which are related to the analysis of the risk of enterprise logistics activity, are proposed to carry out in a certain sequence in the article. This sequence is given in the form of a structural scheme of systematic analysis of the risks of the enterprise logistics activities. Based on the objectivity of the existence of logistics activities' risks and the need to ensure the rational management of them, the algorithm of the risk management in the enterprise logistics system covers the stages of risks' identification, their qualitative and quantitative assessment, diagnostics, assessment of risk acceptability and application of neutralization measures to unacceptable logistical risks. It is concluded that the logistics activities risks combine different types of risks of all components and elements both in the process of changing material, financial and information flows, as well as in the process of managing the risks arising in the logistics system


Author(s):  
I. A. Ilina ◽  
I. A. Machneva ◽  
E. S. Bakun

  The article is devoted to the study of the chemical composition, physical and thermal-pfysical characteristics of damp apple pomaces and the identifying patterns of influence of drying temperature the functional composition and gel-forming ability of pectin. The research is aimed at obtaining initial data for the subsequent calculation of the main technological, hydro-mechanical, thermal, structural and economic characteristics of devices for drying the plant raw materials, ensuring the environmental safety and high quality of pectin-containing raw materials, the reducing heat and energy costs. As a result of the study of the thermal characteristics of apple pomaces, the critical points (temperature conductivity – 16.5 x 10-8 m2/s, thermal conductivity – 0.28 W/m K, heat capacity – 1627 j/(kg K)) at a humidity of 56 % are determined, which characterizing the transition from the extraction of weakly bound moisture to the extraction of moisture with strong bonds (colloidal, adsorption). It was found that the pomaces obtained from apples of late ripening have a higher content of solids (21-23 %), soluble pectin and protopectin (2.5-4.5 %). Dried pomaces obtained from apple varieties of late ripening contain up to 25 % pectin, which allow us to recommend them as a source of raw materials for the production of pectin. The optimum modes of preliminary washing of raw materials are offered, allowing to the remove the ballast substances as much as possible. It is established that when the drying temperature increases, the destructive processes are catalyzed: the strength of the pectin jelly and the uronide component and the degree of pectin esterification are reduced. The optimum drying temperature of damp apple pomaces is 80 0C, at which the quality of pectin extracted from the dried raw materials is maintained as much as possible. It is shown that the most effective for the pectin production is a fraction with a particle size of 3-5 mm, which allow us to extract up to 71 % of pectin from raw materials.


Cancers ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1424
Author(s):  
Antonio Lopez-Beltran ◽  
Fernando López-Rios ◽  
Rodolfo Montironi ◽  
Sophie Wildsmith ◽  
Markus Eckstein

Immuno-oncology (IO) agents (anti–programmed cell death 1 (PD-1) and anti–programmed cell death-ligand 1 (PD-L1)) are approved as first- and second-line treatments for metastatic UC. PD-L1 expression levels in UC tumors help clinicians determine which patients are more likely to respond to IO therapies. Assays for approved IO agents use different antibodies, immunohistochemical protocols, cutoffs (defining “high” vs. “low” PD-L1 expression), and scoring algorithms. The robust control of pre-analytical and analytical standards is needed to obtain high-quality PD-L1 results. To better understand the status and perspectives of biomarker-guided patient selection for anti–PD-1 and anti–PD-L1 agents in UC, three workshops were held from December 2018 to December 2019 in Italy, Malaysia, and Spain. The primary goal was to develop recommendations for best practice approaches to PD-L1 testing in UC. Recommendations pertaining to the interpretation and reporting of the results of PD-L1 assays from experienced pathologists and oncologists from around the globe are included. A test request form for pathology laboratories was developed as a critical first step for oncologists/urologists to encourage communication between clinicians and pathologists, ensuring fast and high-quality test results. In this era of personalized medicine, we briefly discuss novel biomarkers being evaluated for IO agents in UC.


Physics ◽  
2021 ◽  
Vol 3 (2) ◽  
pp. 320-351
Author(s):  
Serge Nagorny

Recent progress in Cs2HfCl6 (CHC) crystal production achieved within the last five years is presented. Various aspects have been analyzed, including the chemical purity of raw materials, purification methods, optimization of the growth and thermal conditions, crystal characterization, defect structure, and internal radioactive background. Large volume, crack-free, and high quality CHC crystals with an ultimate scintillating performance were produced as a result of such extensive research and development (R & D) program. For example, the CHC crystal sample with dimensions ∅23 × 30 mm3 demonstrates energy resolution of 3.2% FWHM at 662 keV, the relative light output at the level of 30,000 ph/MeV and excellent linearity down to 20 keV. Additionally, this material exhibits excellent pulse shape discrimination ability and low internal background of less than 1 Bq/kg. Furthermore, attempts to produce a high quality CHC crystal resulted in research on this material optimization by constitution of either alkali ions (Cs to Tl), or main element (Hf to Zr), or halogen ions (Cl to Br, I, or their mixture in different ratio), as well as doping with various active ions (Te4+, Ce3+, Eu3+, etc.). This leads to a range of new established scintillating materials, such as Tl2HfCl6, Tl2ZrCl6, Cs2HfCl4Br2, Cs2HfCl3Br3, Cs2ZrCl6, and Cs2HfI6. To exploit the whole potential of these compounds, detailed studies of the material’s fundamental properties, and understanding of the variety of the luminescence mechanisms are required. This will help to understand the origin of the high light yield and possible paths to further extend it. Perspectives of CHC crystals and related materials as detectors for rare nuclear processes are also discussed.


2021 ◽  
Author(s):  
Shi-Hyun Seok ◽  
Seungjun Choo ◽  
Jinsung Kwak ◽  
Hyejin Ju ◽  
Ju-Hyoung Han ◽  
...  

A method of pelletizing raw materials was used to tackle unwarranted variations in MXene products depending on the parent MAX phases, manufacturing techniques, and preparation parameters, enabling a direct painting process on various surfaces for ink applications.


2013 ◽  
Vol 734-737 ◽  
pp. 3320-3323
Author(s):  
Kai Wang

With the expansion of consumer market and production scale, the effect of logistics in the enterprise management is also becoming increasingly prominent. But the individual enterprise's logistics system capacity is limited, can not meet the needs of production and consumption timely and the waste of resources in the operation process are the prominent problems in logistics management. This paper explored the logistics system integration ideas and workable solutions of production enterprise from integrated logistics system point of view.


2013 ◽  
Vol 787 ◽  
pp. 382-387
Author(s):  
Li Zhou ◽  
Yuan Kui Ding ◽  
Pai Feng Luo

A facile low-cost non-vacuum process for fabrication of high quality CuInSe2(CIS) films is described, which indicates a promising way for the application in thin film solar cells. First, citrate-capped Cu11In9alloy nanoparticles are synthesized by hot-injection method after a system research on the different reaction time and Cu-In ratio of the raw materials. From the TEM and XRD results, we can see that uniform spherical nanoparticles with dominant Cu11In9phase and less particle-to-particle agglomeration are successfully achieved in this study. Then, employing spray and RTP selenization process, high quality CIS films with dense and big grains are obtained, which show the single chalcopyrite structure and the preferred (112) orientation. An energy band gap about 1.01 eV is measured through the absorption spectroscopy measurement in our work.


2021 ◽  
Vol 1028 ◽  
pp. 365-370
Author(s):  
Diba G Auliya ◽  
Soni Setiadji ◽  
Zulfi Mofa Agasa ◽  
Fitrilawati ◽  
Norman Syakir ◽  
...  

Polydimethylsiloxane (PDMS) has been widely used as a vitreous humour substitution in vitreoretinal surgery. Due to its limited availability and increasing domestic needs, the price of PDMS in Indonesia became very expensive. Previously, we reported the synthesized of PDMS from a high grade of monomer of 98% of Octamethylcyclotetrasiloxane (D4) and found that all PDMS samples produced high quality samples similar to that of commercial one. However, by considering the ease of obtaining raw materials and also the production costs, the synthesis of PDMS using monomer which easy to be found in Indonesia and low production costs is needed to be developed. Here, we reported the synthesis of PDMS using low grade of 96% of D4 in order to produce high quality of PDMS with low viscosity that can be used for vitreous humous substitution in vitreoretinal surgery. PDMS samples with low viscosity value of 0.94-1.35 Pa.s have been successfully synthesized from low grade of D4 and MM using ring-opening polymerization method. The yields of PDMS resulted in this research were in the range between 67.27% and 76.26%. From FTIR spectroscopy, it is found that all synthesized samples have structure and functional groups similar to PDMS using high grade of monomer of 98% Octamethylcyclotetrasiloxane (D4). From refractometer and surfgauge measurements, all samples have refractive index in the range of 1,4034-1,4040 and the value surface tension was 21 m.N/m.


2021 ◽  
pp. 88-96
Author(s):  
N. Spodyniuk ◽  
◽  
L. Horbachenko ◽  

The constant development of the country's agricultural sector allows the production of biofuels, such as fuel pellets, from agricultural waste - straw, corn and sunflower husks. However, the transportation of fuel pellets is quite energy consuming. The process of loading and unloading, transportation over long distances requires complex mechanized equipment. The use of a pneumatic conveyor for grain reloading will allow to provide high-quality transportation of fuel pellets. The aim of the article was to investigate the operation of the pneumatic conveyor for overloading fuel pellets, to determine the optimal indicators that affect the productivity of the pneumatic conveyor. Since fuel pellets, as raw materials, are structurally similar to cereals, a study of the pneumatic grain conveyor PTZ-25 was conducted. The dependence of the productivity of the pneumatic conveyor on the lifting height h, m and the length of the pipelines L, m was obtained. The obtained results showed that by reducing the length of the pipelines by four times and the lifting height by half, the productivity of the pneumatic conveyor will increase by 1.15 times. Key words: fuel pellets, pneumatic conveyor, productivity


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