scholarly journals Hemogram components and platelets count variation in anemic patients attending Birat Medical College and Teaching Hospital, Morang, Nepal

2021 ◽  
Vol 11 (1) ◽  
pp. 1825-1829
Author(s):  
Santosh Upadhyaya Kafle ◽  
Mrinalini Singh ◽  
Neeta Kafle ◽  
Amrita Sinha

Background: Anemia being the expression of the underlying disease is a global public health problemaffecting both developing as well as developed countries. The RBC indices and platelet count variationamong anemic patients are important to know their association for clinical implications.Materials and Methods: A hospital-based cross-sectional study among anemic patients with hemoglobin<10 gm%, attending Birat Medical College Teaching Hospital, Nepal from 15 May to 15 July 2020 wereanalyzed for RBC indices and platelet count variation. Demographic data, RBC indices, platelet countvariation, and types of anemia were evaluated. Pearson’s correlation coefficient was used for correlatingthe platelet count with RBC indices. A Chi-square test was used to know about the association betweenthe types of anemia and platelet count variation.Results: Out of 150 anemic patients, the female to male ratio was 1.5:1, with the most common agegroup between 40-49 years. There exist high differences between minimum and maximum individualRBC indices (Hb, MCV, MCH, MCH) and platelet count values. The platelet count variation with RBCvalues and MCV had a statistically significant positive and negative correlation respectively. However,the correlation between platelet count variation with hemoglobin concentration level and type of anemiawas positive but statistically not significant.Conclusion: Findings suggest that platelet count variation with RBC indices and types of anemiacorrelated well among anemic patients. Such association will enable the clinicians for diagnosing andtreatment purposes.  

2020 ◽  
Vol 5 (2) ◽  
pp. 1104-1109
Author(s):  
Santosh Upadhyaya Kafle ◽  
Mrinalini Singh ◽  
Neeta Kafle ◽  
Amrita Sinha

Introduction: The histopathological examination of appendectomy specimens is the gold standard method for diagnosis. The presence of eosinophil besides other inflammatory cells like neutrophils and mature lymphocytes within different histological layers of appendectomy specimens are common findings for labeling it under various groups. This finding supports the assumption that appendicitis is triggered by Type 1 hypersensitivity reaction.  Objective: To evaluate the eosinophil count variation in appendectomy specimens in patients with the clinical diagnosis of appendicitis.  Methodology: This is a cross sectional hospital based study of 144 appendectomy specimens obtained in Department of Pathology, Birat Medical College Teaching Hospital from January 2019 to December 2019. Socio-demographic data, association of histopathological patterns with age groups, gender and eosinophil count in various histopathological groups was compared and cross-tabulated using SPSS version 16.  Result: Among 144 appendectomy specimens, male gender (50.70%) of 15-24 years age group (36.80%) was predominant. The commonest histopathological diagnosis was acute appendicitis (31.25%) with highest eosinophil count in all of its histological layers. The association of various histopathological patterns with age groups and gender were not statistically significant, whereas it revealed statistically significant correlation between eosinophil counts in all histological layers.  Conclusion: Findings suggest that the eosinophil count variation in the entire histological layers correlate well among different histopathological patterns of appendectomy specimens. This reflects the high diagnostic value of evaluating the eosinophil count in appendectomy specimens. 


Med Phoenix ◽  
2021 ◽  
Vol 6 (1) ◽  
pp. 14-18
Author(s):  
Smita Singh ◽  
Deependra Prasad Sarraf ◽  
Prabin Singh ◽  
Pragati Poudyel

Introduction: Pharmacovigilance helps in the detection and prevention of adverse effects of drugs. For the effectiveness of this program, health care professionals should report adverse drug reactions (ADRs) considering it as their moral and professional obligation. The objective of the study was to assess the knowledge, attitude, and practices (KAP) of the doctors towards ADRs and pharmacovigilance in  National Medical College Teaching Hospital (NMCTH), a tertiary care teaching hospital situated in the Narayani zone. Materials and Methods: A cross-sectional study was carried out using a self-administered questionnaire consisting of four parts; first part included a demographic profile of participants, the second part consisted of ten questions for the assessment of the knowledge about pharmacovigilance, third part comprised of six questions on attitude and fourth part consisted of five questions on practice. The results were depicted in the form of percentages for each KAPs questionnaire.   Results: The response rate of participants was 85.16%. Pharmacovigilance was correctly defined by 52%. Department of drug administration was responsible for monitoring ADRs in Nepal was correctly given by 80%. Only 8% had reported ADRs, although 62% had encountered an ADR in their clinical practice. Conclusion: The doctors at NMCTH had a poor KAP towards pharmacovigilance and educational intervention is needed for the proper functioning of this program.


2018 ◽  
Vol 7 (1) ◽  
pp. 45-49
Author(s):  
Manish Pradhan ◽  
Chandra Bhal Jha ◽  
Dipa Rai

Background: Acne is a very common distressing skin condition that affects multiple aspects of quality of life of an individual. It has been illustrated that acne have tremendous effect on an individual’s self-image and impacts his or her quality of life. The extent of burden of the disease experienced by the patients seems to be underestimated by the whole medical fraternity. The aim of the study is to determine the health related quality of life impairment in acne patients using CADI and to identify various variables that increase the patients’ susceptibility for quality of life impairment. Subjects and Methods: This is a hospital based, cross sectional study conducted in the Department of Dermatology, Nobel Medical College Teaching Hospital from Jan 2017 to December 2017.A total of 202 acne patients were evaluated with CADI. Clinical characteristics were recorded after history and clinical examination. Results: Out of total 202 patients enrolled, 56.4% of patient scored a CADI score of (5-9) indicating moderate quality of life impairment and 15.3% of patient scored a CADI score of 10 or more indicating severe quality of life impairment. The mean CADI score was 6.82 ± 2.75. There was positive correlation between the CADI score and impact on quality of life with grade of acne, which was statistically significant (p<0.001). Conclusion: Acne is a common skin disease with tremendous adverse effect on the patient’s health related quality of life. Patients are affected both physically and mentally with this condition. Journal of Nobel Medical College Volume 7, Number 1, Issue 12, January-June 2018, Page: 45-49 


2018 ◽  
Vol 8 (1) ◽  
pp. 1285-1288
Author(s):  
Sailesh Bahadur Pradhan ◽  
Binita Pradhan ◽  
Sailuja Maharjan ◽  
Prabin Bikram Thapa

Background: Gastrointestinal tract tumour is responsible for more cancers and death than any other cancers.  The tumour in GIT include the tumour of the Oral cavity, Esophagus, Stomach, Colon, Rectum, Liver, Gallbladder, Pancreas and Biliary tree.Materials and methods: A cross sectional study was carried out among all the gastrointestinal tract tumours specimens received for histopathological examination in between January 2016 to June 2017 in Department of Pathology, Kathmandu Medical College Teaching Hospital. All tumors diagnosed either benign or malignant were included in this study. Ethical clearance was obtained from the Institutional Review Committee in KMCTH.Results: Colorectum was found to be the most commonly involved site for malignant lesion comprising 40.2% among all malignant lesions followed by stomach comprising 28.6%. Malignancy was found to be more prevalent among male with M:F ratio of 1.6:1 in colorectal region and 1.4:1 in stomach cancers. Regarding benign lesions (polyps), rectum was found to be the commonest site (57.5%), followed by colon (20.0%) and stomach, the least common site.Malignant lesions were more common among the age group of 51-60 years (37.66%) with 70.13% above 50 years. Benign lesions were also found to be the most common above 50 years comprising 40.0 percent.Conclusion: Rectum & colon was found to be the most commonly involved site for both malignant and benign lesion. Malignancy is more prevalent among male and common above 50 years of age. However, malignant cases noted in the adult age group are a matter of great concern.


2020 ◽  
Vol 11 (3) ◽  
pp. 62-66
Author(s):  
Renu Yadav ◽  
Nisha Ghimire ◽  
Soumitra Mukhopadhyay ◽  
Subodh Kumar Yadav

Background: Studies have concluded that the medical students of hostels are at high risk of anemia due to inappropriate diet and their long schedules that indirectly affect their performance. Thus, concerning for the long duration of medical studies, it has become a serious medical issue. Aims and Objective: Thus, our objective is to determine the prevalence of anemia among medical students in Nobel Medical College and Teaching Hospital, Nepal. Materials and Methods: This is a descriptive cross-sectional study which was conducted and Teaching Hospital from January 2017 to December 2017 where all the subjects were selected with convenient sampling technique. The total of 150 MBBS students (male=95, female=55), age 18-25 years were included in the study who were clinically healthy. The demographic data (name, age, sex, address) and anthropometric variables (height, weight, body mass index) were recorded and hemoglobin was estimated by Sahli’s acid hematin method. Results: Only 42.1% of total were mild anemic and 11.6 % were moderately anemic. Among female, 1.8% were severely anemic, 9.1% were moderately anemic and 41.8% were mild anemic. Compared to male, anemia in female medical students was found to be more extensive. Conclusions: It has been concluded from the above study that the mild anemia is highly prevalent among medical students regardless of gender. Though the subjects are not severely affected, it is a concerned issue since the cause might be inappropriate food habit or the food facilities available at hostels.


2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Ishwori Khatri Chhetri ◽  
Bedantakala Thulung

Background. Critical care units’ nurses should seek to develop collaborative relationships with patients’ family members based on their needs and help them to cope with their distress. The objective of this study was to find out the perception of nurses on needs of family members of patients admitted to critical care units.Methods. A descriptive cross-sectional study was conducted in Chitwan Medical College Teaching Hospital among all 65 nurses working in critical care units. Ethical clearance was obtained from Chitwan Medical College Institutional Review Committee. Data were collected from March 27 to April 25, 2016, using Critical Care Family Needs Inventory (CCFNI). Obtained data were analyzed using descriptive and inferential statistics.Results. This study found that mean age of the nurses was 23.98 ± 4.05 years. More than half of the nurses had completed PCL in nursing (52.3%) and had 1-5 years of experience in critical care units (58.5%). Nurses ranked the needs for assurance as most important needs with mean percent (86.25%) followed by needs for information (78.58%), need for comfort (69.59%), needs for closeness (69%), and needs for support (64.13%). Out of 45 family needs, 81.5% of nurses perceived that knowing about patient treatment is very important for family members. Married nurses perceived the needs for support to be more important than unmarried nurses (p=0.04) whereas unmarried nurses perceived the needs for information to be more important than married (p=<0.01). There was significant difference on perception of nurses on needs of assurance with ethnicity (p=0.009) and critical care experience (p=0.04).


2019 ◽  
Vol 57 (219) ◽  
Author(s):  
Sunil Raja Manandhar ◽  
Rydam Basnet

  Introduction: Perinatal asphyxia is one of the major causes of perinatal and early neonatal mortality in developing countries. The main objective of this study was to observe the prevalence of perinatal asphyxia in babies born at Kathmandu Medical College Teaching Hospital. Methods: This was a descriptive cross-sectional study conducted at Kathmandu Medical College Teaching Hospital over six month period (January to June 2019). All preterm, term and post term babies delivered at Kathmandu Medical College Teaching Hospital were included. Ethical clearance was received from Institutional Review Committee of Kathmandu Medical College (Ref.:2812201808). Convenient sampling method was applied. Data analysis was done in Statistical Package for Social Sciences (SPSS 18), point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data. Results: A total of 1284 babies delivered over six months period were enrolled in this study and 47 (3.66 %) babies were asphyxiated, at 95% Confidence Interval (2.64%-4.68%). The mean birth weight of asphyxiated babies was 2759.75±65 grams and gestational age was 37.57±2 weeks. Among asphyxiated babies, 15 (32%) babies were normal, 15 (32%) babies were in Hypoxic Ischemic Encephalopathy stage I, 14 (30%) were in stage II and 3 (6%) were in stage III. Twenty Three (49%) asphyxiated babies had antenatal risk factors and all 47 babies had intrapartum risk factors leading to asphyxia. Conclusions: Prevalence of perinatal asphyxia was lower compared to that of other similar tertiary care hospitals. Perinatal asphyxia remains a major cause of neonatal morbidity and mortality.


2020 ◽  
Vol 6 (1) ◽  
pp. 3-19 ◽  
Author(s):  
Susmita Shrestha ◽  
Bibek Khadka

Correction: The page numbers on this article were changed from 4-20 to 3-19 on 31/08/2020. Introduction: We presume that the knowledge of patients about Magnetic Resonance imaging (MRI) scan is of utmost importance for smooth workflow, patient comfort, patients’ safety and to mitigate patients’ compliance and save valuable scan time. Therefore, the purpose ofthis study was to determine the awareness of patients undergoing MRI scan regarding Knowledge, Perception and Safety. Methods: This descriptive cross-sectional study was carried out in Chitwan Medical College Teaching Hospital from April to September, 2018. Total of 310 patients referred to undergo MRI scan were assessed by a questionnaire form covering 4 parts: Part 1- aimed to gather the socio demographic data such as age, sex, occupation and educational status of patients, Part 2- included the knowledge regarding MRI and its safety, Part 3- comprised the patient perception before MRI scan and Part 4 constituted the patient perception after MRI scan.The form was filled by an investigator oneself in a face to face interview with the patients. Results: Among 310 patients, 35.2% were illiterate and 19.4% graduated from high school. Majority of 85.5% patients answered that MRI uses harmful ionizing radiation like CT scan and radiography. Almost 43 patients who answered MRI functions in disease treatment also answered decreased in pain after MRI scan (Male = 15 and Female = 28) were in age group between 25 years and 50 years. This study also revealed that majority of 26.8% (i.e. n = 83) patients faced problem as claustrophobia along with anxiety during the scan, out of which 13 patients have history of previous MRI scan. Conclusions: In our study decrease in pain was higher in diagnosis and treatment answer. Majority of the patients faced anxiety along with claustrophobia during the MRI scan. Assessment of patient knowledge, perception and safety regarding MRI scan can be the key to increase patient compliance and save valuable scan time.


2020 ◽  
Vol 6 (1) ◽  
pp. 39-49
Author(s):  
Indira Adhikari Poudel ◽  
B Bhattarai ◽  
P Dhakal

Correction: The page numbers were changed from 57-67 to 39-49 on 31/08/2020. Background: Cesarean section (CS) rate has increased rapidly over the past two decades in world. It is serious concern for public health experts globally. Various medical and non-medical factors, such as maternal socio-demographics, are found to be responsible for this upsurge. Like in other countries, the rate of caesarean sections has increased in Nepal as well. Therefore, there is a need to investigate the factors behind this increase. Objectives: To identify the factors associate for caesarean section among mothers attending at teaching hospital, Chitwan Methods: A cross sectional analytical study was conducted using total enumerative sampling technique in the maternity ward of Chitwan Medical College Teaching Hospital. Interview was done with closed ended Questionnaire for data collection, a total number of 139 mothers after 24 hours cesarean section (CS). Results: The study shows that, nearly three- quarters (71.2%) of CS were performed as an emergency. There are mainly fetal, maternal and placental indication for cesarean section. The most frequent indications were: previous cesarean section (22.3%), thick Meconium stained liquor (12.2%), fetal distress (10.6%) and oligohydramnios (7.2%).


2015 ◽  
Vol 4 (3) ◽  
pp. 34-37 ◽  
Author(s):  
H K Subba ◽  
R Subba

Chronic obstructive pulmonary disease is a major cause of morbidity and mortality worldwide and global health concern. COPD self care knowledge is a cornerstone for self-management of chronic illness. The objective of this study was to find out the level of knowledge on self care among COPD patients. A descriptive, cross sectional design and purposive sampling was applied in which 182 patients were interviewed by using semi-structure interviews schedule at Chitwan Medical College, Teaching Hospital, Bharatpur. Data was analyzed by using SPSS and descriptive and inferential test was applied. The study findings revealed that 36.8% of the respondents were between age group 61-70 years, 54.4% respondents were male, 59.9% were from Chitwan district, majority of the respondents (62.1%) were outpatient, 48.4% had a history of COPD more than 5 years, 83.2%were hospitalized 1-2 times in last year, 63.2% had no history of COPD in family members and all respondents got information from health personnel. Highest percentage (75) of mean score on smoking cessation and lowest (10) on weight monitoring. Most of all respondents (90.7%) had poor level of knowledge on self care of COPD. The respondents’ level of knowledge on self care is statistically significant with family history (p=0.048), educational status (p=0.000), and types of patient (p=0.017).So, there should be need of health education program for COPD patients about self care to improve knowledge. DOI: http://dx.doi.org/10.3126/jcmc.v4i3.11938Journal of Chitwan Medical College 2014; 4(3):34-37 


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